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  1. 265701
    “…Trainees found the tutorial interesting, enjoyable, clearly presented, and useful for professional development. …”
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    A Web-Based Therapist Training Tutorial on Prolonged Grief Disorder Therapy: Pre-Post Assessment Study
  2. 265702
    “…Untargeted metabolomics analysis identified 28 upregulated and 4 downregulated differential metabolites in feces and 11 upregulated and 16 downregulated differential metabolites in serum under AR conditions. Interestingly, one of the significant difference metabolites, α-Linoleic acid (ALA), decreased consistently in feces and serum of AR. …”
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    Fecal and serum metabolomic signatures and gut microbiota characteristics of allergic rhinitis mice model
  3. 265703
    “…In this study, we analysed the effects of early antibiotic exposure on outcomes in almost 4,100 patients with hepatocellular carcinoma treated within nine multicentre clinical trials. Interestingly, early exposure to antibiotic treatment was associated with worse outcomes not only in patients treated with immune checkpoint inhibitors but also in those treated with tyrosine kinase inhibitors and placebo. …”
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    Association between antibiotics and adverse oncological outcomes in patients receiving targeted or immune-based therapy for hepatocellular carcinoma
  4. 265704
    “…RESULTS: The number of Mpox posts and the number of posts with Mpox and 2SLGBTQIAP+ keywords were 85% correlated (P<.001). Interestingly, the number of posts with Mpox and 2SLGBTQIAP+ keywords had a higher correlation with the number of Mpox cases (correlation=0.36, P<.001) than the number of posts on Mpox (correlation=0.24, P<.001). …”
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    Mpox Panic, Infodemic, and Stigmatization of the Two-Spirit, Lesbian, Gay, Bisexual, Transgender, Queer or Questioning, Intersex, Asexual Community: Geospatial Analysis, Topic Modeling, and Sentiment Analysis of a Large, Multilingual Social Media Database
  5. 265705
    “…Two of these four patients as well as two other patients yielded pronounced [(89)Zr]Zr-Df-IAB22M2C uptake within nonmetastatic lymph nodes. Interestingly, cancer progression in ICT patients was associated with a relatively low [(89)Zr]Zr-Df-IAB22M2C uptake in the spleen compared to the liver in 4 out of the 6 patients. …”
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    In vivo imaging of CD8(+) T cells in metastatic cancer patients: first clinical experience with simultaneous [(89)Zr]Zr-Df-IAB22M2C PET/MRI
  6. 265706
    “…Most dominant drivers were located in the upper right atrium or left pulmonary vein region (Figure 2). Interestingly, only 9 of the 130 initially detected drivers (7%) showed an activation pattern in line with a repetitive entrainment of their vicinity. …”
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    Detection of the most dominant drivers of atrial fibrillation based on repetitive activity in sequential electro-anatomical mapping
  7. 265707
    “…Patients with ventricular tachycardias showed significantly more severe left ventricular (LV) hypertrophy, reduced LV ejection fraction (LV-EF) and larger left atrial volumes as well as a trend towards smaller LV cavities (table 1). Interestingly, no significant differences in prevalence of coronary artery disease or cardiac markers such as NTproBNP and troponin were seen between patients with and without ventricular tachycardias (table 1). …”
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    Left ventricular hypertrophy, dilatation and ejection fractions predict ventricular tachycardia in amyloid transthyretin cardiomyopathy
  8. 265708
    “…Another five case reports (between 2018 and 2021) revealed an additional five subjects (one case per paper) diagnosed with LS and ACC (female to male ratio of 4 to 1; aged between 44 and 68). Interesting genetic testing involved children with TP53-positive ACC and further MMR anomalies or an MSH2 gene-positive subject with LS with a concurrent germline RET mutation. …”
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    Pathogenic Insights into DNA Mismatch Repair (MMR) Genes–Proteins and Microsatellite Instability: Focus on Adrenocortical Carcinoma and Beyond
  9. 265709
    “…Also, NLRP3 (rs4612666) TT genotype was more frequent in patients with higher DAS-28 (P < 0.0001) and higher TNF-α and IL- 1β serum levels (P < 0.0001 for both). Interestingly, this study revealed that CARD8 (rs2043211) and NLRP3 (rs4612666) variant genotypes are associated with lower response to anti-TNF-α drugs. …”
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    Effect of NLRP3 inflammasome genes polymorphism on disease susceptibility and response to TNF-α inhibitors in Iraqi patients with rheumatoid arthritis
  10. 265710
    “…A parental questionnaire (SRS-2) was used to measure the incidence of behaviors in two key behavioral domains associated with ASD: Social Communication and Interaction and Restricted Repetitive Behaviors and Interests. At baseline, we assessed children's expressive and receptive language abilities as well as their intellectual functioning with standardized tests. …”
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    Behaviors related to autism spectrum disorder in children with developmental language disorder and children with 22q11.2 deletion syndrome
  11. 265711
    “…BACKGROUND: The [(177)Lu]Lu-DOTA-TATE mediated peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs) is sometimes leading to treatment resistance and disease recurrence. An interesting alternative could be the somatostatin antagonist, [(177)Lu]Lu-DOTA-JR11, that demonstrated better biodistribution profile and higher tumor uptake than [(177)Lu]Lu-DOTA-TATE. …”
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    First preclinical evaluation of [(225)Ac]Ac-DOTA-JR11 and comparison with [(177)Lu]Lu-DOTA-JR11, alpha versus beta radionuclide therapy of NETs
  12. 265712
    “…Similarly, there was no significant difference in the relationships between the inflammatory biomarkers (IL-6, IL-8, IL-10, TNF-α and CRP) and the CSI, BSI, and ISI in the femoral neck. Interestingly, in concomitant inflammation-related chronic diseases, only arthritis affected the soluble IL-6 receptor and the CIS (interaction P = 0.030) and SIS (interaction P = 0.050) in the femoral neck. …”
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    Associations between blood inflammatory markers and bone mineral density and strength in the femoral neck: findings from the MIDUS II study
  13. 265713
    “…NH(2) conjugates in comparison to free (134)CeCl(3) confirmed high in vivo stability. An interesting observation during the radiolabeling of tumor-targeting vectors PSMA-617 and MACROPA-PEG(4)-YS5—that the daughter (134)La was expelled from the chelate after the decay of parent (134)Ce—was confirmed through radio–thin-layer chromatography and reverse-phase high-performance liquid chromatography. …”
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    Evaluation of (134)Ce/(134)La as a PET Imaging Theranostic Pair for (225)Ac α-Radiotherapeutics
  14. 265714
    “…The growth of xenografts from RKO cells overexpressing miR663AHG was slower than that of xenografts from vector control cells in BALB/c nude mice (P = 0.007). Interestingly, either RNA-interfering or resveratrol-inducing expression changes of miR663AHG or miR663a can trigger negative feedback regulation of transcription of the MIR663AHG gene. …”
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    LncRNA miR663AHG represses the development of colon cancer in a miR663a-dependent manner
  15. 265715
    “…CONCLUSION: While over the past decade aesthetic surgery costs have changed, certain procedure costs such as the rhytidectomy have greatly increased, while others have modestly increased, and liposuction has even decreased. Interestingly, the cost for the majority of the most performed aesthetic procedures are not greatly impacted by inflation. …”
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    A Temporal Analysis of the Cost of Aesthetic Surgical Procedures Over the Past Decade in Relation to Consumer Price Indices and the Stock Market
  16. 265716
    “…Input from a multidisciplinary team of experts and stakeholders can ensure the program’s success. Those interested in adapting programs should have a realistic estimate of the budget and staffing requirements.…”
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    Adapting a Telephone-Based, Dyadic Self-management Program to Be Delivered Over the Web: Methodology and Usability Testing
  17. 265717
    “…Next, we probed the role of OGA inhibition in regulating ERK activation using mice brain-tissue samples. Interestingly, 6-month intra-peritoneal TMG injection in C57BL/6J mice showed an increase in amplitude of p-ERK and APP protein levels, indicating long-term OGA inhibition potentially contributes to AD progression. …”
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    O-GlcNAcylation regulates extracellular signal-regulated kinase (ERK) activation in Alzheimer’s disease
  18. 265718
    “…Therefore, we visualized an interesting research opportunity based on the circular economy approach. …”
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    A Circular Economy Approach to Integrate Divergent Ruminant Production Systems: Using Dairy Cow Feed Leftovers to Enhance the Out-of-Season Reproductive Performance in Goats
  19. 265719
    “…Results: Comparing postoperative expression of G1 and G3, there was a significantly higher PD-L1 expression (p = 0.015) in G1 compared to G3 and a significantly lower IL-6 (p = 0.001) and FOXP3 (p = 0.016) expression. Interestingly, IL-10 expression was higher pre- (0.05) and postoperative (p < 0.001) in G1 compared to G3. …”
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    Postoperative Changes in Systemic Immune Tolerance Following Major Oncologic versus Minor Maxillofacial Surgery
  20. 265720
    “…Using these techniques, it is shown how competitive pathways at operating conditions can be discovered and how broad transition state regions can be explored. Interestingly, such simulations can also be used to study hindered diffusion under operating conditions. …”
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    Operando Modeling of Zeolite-Catalyzed Reactions Using First-Principles Molecular Dynamics Simulations
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