“…Most of the AYA indicated that they were very likely to use the demonstrated game prototype to help with getting tested for HIV (median 3.0, IQR 2.0-3.0, using a scale ranging from 0 to 3, with 3 indicating high likelihood) and strongly agreed that the game was interesting (median 5.0, IQR 5.0-5.0), fun (median 5.0, IQR 4.0-5.0), and easy to learn (median 5.0, IQR 5.0-5.0, using a scale ranging from 1 to 5, with 5 indicating strong agreement). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, for each disease type, 3 patient profiles were identified, which provide interesting insight for improving therapeutic adherence and adjustment strategies specifically according to patient behavior. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Seven patients achieved a complete response (CR) as the best response at any time on study, while 13 patients had a partial response (PR) and 10 patients had stable disease (SD). Interestingly, the response rate was not statistically different between HCL and HCL-V patients, suggesting that ibrutinib could be an option in both entities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The opioid epidemic in the U.S has gotten payers, prescribers, and policymakers alike interested in trends in opioid use. Despite no recognized opioid crisis in Europe, several countries have reported an increase in opioid-related deaths, which has further prompted discussion on the need of monitoring of opioid prescriptions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we have generated single cell-derived clonal cultures of the quasimesenchymal PDAC-derived cell line, PANC-1, and found that these differ strongly with respect to cell morphology and EMT marker expression, allowing for their tentative classification as E, E/M or M. Interestingly, the different EMT phenotypes were found to segregate with differences in tumorigenic potential in vitro, as measured by colony forming and invasive activities, and in circadian clock function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We sampled both physicians who joined the CAPS-CPCA VCoP and those who were interested in providing the novel practice but did not join the VCoP. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…(Arg32Cys) accounted for 25% (n = 11/44 families) of familial cases, of which 80% (n = 12/15) were consanguineous. Interestingly, the previously reported “Ghanaian” founder variant, GJB2: c.427C>T: p.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The results suggest that HIRT can be an interesting approach for improving physical fitness and adjusting the hormonal and antioxidant levels of adult male soccer players. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we report an outbreak caused by sequence type 859-K19 (ST859-K19) CR-hvKP isolates in a teaching hospital in China. Interestingly, K. pneumoniae ST859 was a single-locus variant of ST11 but has never been reported before. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The use of virtual reality exergames combined with a telerehabilitation app (VirTele) may be an interesting alternative to rehabilitate the UE sequelae in survivors of chronic stroke while allowing for ongoing monitoring with a clinician. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both genetic predisposition and environmental factors play a role in disease development which are identical in dogs and humans in contrast to other experimental animals. Interestingly, different dog breeds have been shown to develop distinct DCM phenotypes, and this presents a unique opportunity for modeling as there are multiple breed-specific models for DCM with less genetic variance than human DCM. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…No absorption was detected from the stomach, and the least was from the colon (0.19%). Interestingly, RXn-02 exhibited in vitro antiproliferative activities against hub gene hyper-expressing cell lines; A549 (IC(50) = 48.1 μM), K-562 (IC(50) = 100 μM), and MCF7 (IC(50) = 0.047 μM) and against five cell lines originating from human lungs (IC(50) range of 33.2–69.5 μM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The recent technological advances in genome-wide profiling techniques have allowed the exploration of the molecular heterogeneity of this disease, even though some potentially interesting biomarkers such as conjoined genes have not been deeply investigated yet. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…FEA was applied on an upright cylindrical volume of interests (VOI) with its axis coinciding with the tibial bone axis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVES: Lateral extra-articular tenodesis (LET) reduces ACL graft failure rates two years after surgery when performed as an adjunct to ACL reconstruction (ACLR). Interestingly, previous biomechanical studies have shown that LET may reduce tibial rotation beyond that of the intact knee, while others found no such kinematic overconstraint. …”
Enlace del recurso
Enlace del recurso

“…Eleven (19%) respondents thought that students should not have been on clinical placement during the pandemic but a further 51% (n = 30) were happy with the students on placement and expressed willingness to delegate work to students. Interestingly, 58% (n = 34) of CTs suggested that future graduates may need a longer preceptorship after they graduate due to receiving decreased clinical experience during the pandemic. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In silico modelling of CYP4F3 in complex with POR and Cytb5 suggests that the loss of catalytic activity of the mutant CYP4F3 is explained by a disruption of an α‐helix that is crucial for the electron shuffling between the electron carriers and CYP4F3. Interestingly, zileuton still inhibits ex vivo LTB4 production in patient's whole blood to 2% of control (P < 0.0001), while montelukast and fluticasone do not (99% and 114% of control, respectively). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We were particularly interested in the inclusion of people from marginalized sociodemographic groups, whether the TAMI addressed sociocontextual factors, and how behavioral and health outcomes were reported. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Almost all solutes exhibited the highest S with the tetrabutylammonium acetate system, indicating that weakly ionized anions (such as acetate ions) in ion-pair reagents will improve the S values of sulfonic acid compounds. Interestingly, the CHIs of the solutes were almost the same for solutes with different non-counter ions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, only in OL+ samples there was the accumulation of α-terpineol to which a wide range of interesting biological properties is attributed. The presence of VOCs associated with health status suggests a favorable role of OL in preserving and improving animal welfare.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso