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266121por Anderson-Bill, Eileen Smith, Winett, Richard A, Wojcik, Janet R, Winett, Sheila G“…High initial levels of self-efficacy may be characteristic of Web-health users interested in online interventions and may alter the function of SCT in these programs. …”
Publicado 2011
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266122por Shatunov, Aleksey, Mok, Kin, Newhouse, Stephen, Weale, Michael E, Smith, Bradley, Vance, Caroline, Johnson, Lauren, Veldink, Jan H, van Es, Michael A, van den Berg, Leonard H, Robberecht, Wim, Van Damme, Philip, Hardiman, Orla, Farmer, Anne E, Lewis, Cathryn M, Butler, Amy W, Abel, Olubunmi, Andersen, Peter M, Fogh, Isabella, Silani, Vincenzo, Chiò, Adriano, Traynor, Bryan J, Melki, Judith, Meininger, Vincent, Landers, John E, McGuffin, Peter, Glass, Jonathan D, Pall, Hardev, Leigh, P Nigel, Hardy, John, Brown, Robert H, Powell, John F, Orrell, Richard W, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Al-Chalabi, Ammar“…The threshold for significance was p=0·05 in the independent analysis, because we were interested in replicating a small number of previously reported associations, whereas the Bonferroni-corrected threshold for significance in the joint analysis was p=2·20×10(−7) FINDINGS: After quality control, samples were available from 599 patients and 4144 control individuals in the independent set. …”
Publicado 2010
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266123por Tatsi, Aikaterini, Maina, Theodosia, Cescato, Renzo, Waser, Beatrice, Krenning, Eric P, de Jong, Marion, Cordopatis, Paul, Reubi, Jean Claude, Nock, Berthold A“…BACKGROUND: In this study, we report on the synthesis, radiolabeling, and biological evaluation of two new somatostatin-14 (SS14) analogs, modified with the universal chelator DOTA. We were interested to investigate if and to what extent such radiotracer prototypes may be useful for targeting sst(1-5)-expressing tumors in man but, most importantly, to outline potential drawbacks and benefits associated with their use. …”
Publicado 2012
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266124por Hemmings, K.E., Maruthini, D., Vyjayanthi, S., Hogg, J.E., Balen, A.H., Campbell, B.K., Leese, H.J., Picton, H.M.“…STUDY FUNDING/COMPETING INTERESTS: This project was funded by the UK Biology and Biotechnology Research Council (BB/C007395/1) and the Medical Research Council (G 0800250). …”
Publicado 2013
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266125“…Discussions with hospital personnel regarding specific trends, characteristics and interests helped to strengthen the relationship the DOHMH has with the hospital ED staff. …”
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266126por Yuasa-Sunagawa, Mayumi, Zhang, Ye, Yeshitla, Samrawit A., Kadhim, Munira A., Wilson, Bobby L., Wu, Honglu“…Increasing doses of exposure resulted in less fraction of chromosome break ends involved in intra-chromosomal exchange induced by either gamma rays or Fe ions in the first mitosis. Interestingly, simple inversions in chromosome 3 were found in only the 7 and 14-day samples after 4 Gy gamma irradiation. …”
Publicado 2014
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266127por Mao, Chen, Wu, Xin-Yin, Fu, Xiao-Hong, Di, Meng-Yang, Yu, Yuan-Yuan, Yuan, Jin-Qiu, Yang, Zu-Yao, Tang, Jin-Ling“…Importantly, publicly available Internet data are open to any interested researchers and can thus greatly facilitate the investigation and control of such outbreaks. …”
Publicado 2014
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266128por DeDiego, Marta L., Nieto-Torres, Jose L., Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Castaño-Rodriguez, Carlos, Fernandez-Delgado, Raul, Usera, Fernando, Enjuanes, Luis“…The modification or deletion of different motifs within E protein, including the transmembrane domain that harbors an ion channel activity, small sequences within the middle region of the carboxy-terminus of E protein, and its most carboxy-terminal end, which contains a PDZ domain-binding motif (PBM), is sufficient to attenuate the virus. Interestingly, a comprehensive collection of SARS-CoVs in which these motifs have been modified elicited full and long-term protection even in old mice, making those deletion mutants promising vaccine candidates. …”
Publicado 2014
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266129por Irvine, A Blair, Russell, Holly, Manocchia, Michael, Mino, David E, Cox Glassen, Terri, Morgan, Rebecca, Gau, Jeff M, Birney, Amelia J, Ary, Dennis V“…CONCLUSIONS: This research demonstrated that a theoretically based stand-alone mobile-Web intervention that tailors content to users’ preferences and interests can be an effective tool in self-management of low back pain. …”
Publicado 2015
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266130por Pechmann, Cornelia, Pan, Li, Delucchi, Kevin, Lakon, Cynthia M, Prochaska, Judith J“…Participants were adult smokers who were interested in quitting and were recruited using Google AdWords. …”
Publicado 2015
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266131“…CONCLUSIONS: Physician-rating websites are an interesting new source of information about the quality of health care from the patient’s perspective. …”
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266132“…With this availability of information, one can now address interesting questions, such as: what chemical fragments are known today? …”
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266133por Rai, Himanshu, Sinha, Nakul, Kumar, Sudeep, Sharma, Ajay Kumar, Agrawal, Suraksha“…Subgroup analysis, however, yielded interesting results, where significant differences in association statuses were seen for IL1A +4845 G>T, IL1B -511 C>T, IL1RN 86bp VNTR and IL1RN +8006 T>C for select ancestral subgroups. …”
Publicado 2016
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266134por Bottorff, Joan L, Oliffe, John L, Sarbit, Gayl, Sharp, Paul, Caperchione, Cristina M, Currie, Leanne M, Schmid, Jonathan, Mackay, Martha H, Stolp, Sean“…METHODS: A one-group, pretest-posttest study design was used. Men who were interested in quitting were recruited and invited to use the website over a 6-month period. …”
Publicado 2016
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266135“…The expressions of metastasis-related proteins of MMP-2, MMP-9 were decreased, whereas the expression of E-cadherin protein was increased by quercetin in a dose-dependent manner. Interestingly, the anti-TLR4 (2 μg) antibody or pyrrolidine dithiocarbamate (PDTC; 1 μM) could affect the inhibition of quercetin on cell migration and invasion, as well as the protein expressions of MMP-2, MMP-9, E-cadherin, TLR4, and NF-κB p65. …”
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266136por Wright, Rick W.“…Meniscal and AC pathology was not found to be a significant risk factor for 2 year activity levels. Interestingly, previous AC pathology and current meniscal pathology were not found to be significant risk factors for 2 year outcomes in this revision cohort. …”
Publicado 2015
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266137por Ribeiro-Romão, Raquel Peralva, Saavedra, Andrea Franco, Da-Cruz, Alda Maria, Pinto, Eduardo Fonseca, Moreira, Otacilio C.“…(V.) braziliensis, an increase in the expression of all immunological markers evaluated was observed, ranging from 2.7 ± 0.2 for TGF-β to 1018.5 ± 809.0 for iNOS in skin lesions, and 2.4 ± 1.6 for TGF-β to 600.2 ± 666.4 for iNOS in popliteal lymph nodes. Interestingly, significantly higher levels of IFN-ɣ, TNF and IL-10 mRNA were observed in skin in comparison to lymph nodes, while a lower significant level of arginase mRNA was observed in skin. …”
Publicado 2016
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266138“…More tailored offerings are needed which consider the preferences and interests of adolescents as well as a cooperation between public health actors to reduce barriers to OS. …”
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266139por Sampaio, Vanderson S., Beltrán, Tatiana P., Kobylinski, Kevin C., Melo, Gisely C., Lima, José B. P., Silva, Sara G. M., Rodriguez, Íria C., Silveira, Henrique, Guerra, Maria G. V. B., Bassat, Quique, Pimenta, Paulo F. P., Lacerda, Marcus V. G., Monteiro, Wuelton M.“…Ivermectin, an endectocide drug efficacious against a range of Anopheles species, could be added to other drug-based interventions. Interestingly, ivermectin could also be useful to target outdoor feeding and resting vectors, something not possible with current vector control tools, such as impregnated bed nets or indoor residual spraying (IRS). …”
Publicado 2016
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266140por Wang, Yuan, Lieberman, Rachel, Pan, Jing, Zhang, Qi, Du, Meijun, Zhang, Peng, Nevalainen, Marja, Kohli, Manish, Shenoy, Niraj K., Meng, Hui, You, Ming, Wang, Liang“…Docetaxel treatment induced higher expression of miR-375 with 5.83- and 3.02-fold increases in DU145 and PC-3 cells, respectively. Interestingly, miR-375 appeared to play a dual role in prostate cancer proliferation. …”
Publicado 2016
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