“…ES in tibia decreased from 78.6(3.2) N/mm to 65.0(2.3) N/mm (p = .01) and 53.1(2.9) N/mm to 44.0(1.7) N/mm (p = .02) from 6 to 22 months in males and females respectively. Interestingly, ES in ulna increased from 8.2(0.8) N/mm to 10.9(1.0) N/mm (p = .051) from 6 to 22 months of age in females only. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Performance of pantomime gestures was poorer compared to imitative gestures. Interestingly, this pattern was also observed during the re-test time point (p<0.0001), though gesture performance for imitative gestures significantly declined compared to baseline in patients (p<0.05). …”
Enlace del recurso
Enlace del recurso

“…Each CRASH factor was associated with different outcome, which is why it can be interesting to analyze the total CRASH score and each factor separately. …”
Enlace del recurso
Enlace del recurso

“…DISCUSSION: According to previous research, our preliminary findings indicated theory of mind deficits in patients with FESz. Interestingly, in our study the alterations on the interpretation and recognition of facial expressions were shown only of negative and neutral, but not of positive facial expressions. …”
Enlace del recurso
Enlace del recurso

“…In addition, beta receptors have unique localization in cortical regions (i.e., hippocampus), and improve social behaviors and cognition in some animal models, which has led to interests in these compounds for testing in schizophrenia. …”
Enlace del recurso
Enlace del recurso

“…From a neuroanatomical perspective, VM relies on a network of brain regions, including the hippocampus (HC) as an important hub in the acquisition of new information. Interestingly, many of the brain regions that differ between males and females, including the HC, show structural abnormalities in psychosis. …”
Enlace del recurso
Enlace del recurso

“…The Family Environment Scale (FES) evaluated family emotional climate in different categories: COHESION (C) for mutual reliance; EXPRESSIVITY (EX), the extent to which family members express their feelings directly; CONFLICTS (CON) for open expression of anger, aggressiveness and conflict; INDEPENDENCE (IND), the extent to which family members are independent in their decisions; ACHIEVEMENT ORIENTATION (AO) for an achievement-orientated environment; INTELLECTUAL–CULTURAL ORIENTATION (ICO) for political, intellectual, cultural interests; ACTIVE–RECREATIONAL ORIENTATION (ARO) for participation in social activities; MORAL–RELIGIOUS EMPHASIS (MRE) for the importance given to ethical and religious practices and values; ORGANIZATION (ORG) for the organization in activities and responsibilities; and CONTROL (CTL), the extent to which the family considers rules and established procedures. …”
Enlace del recurso
Enlace del recurso

“…Neuropsychopharmacology 2015). Interestingly, prediction accuracy in first-episode psychosis is lower compared to older and probably more chronic patients. …”
Enlace del recurso
Enlace del recurso

“…Out of these, 14 were located in gene-coding regions. Interestingly, 9 of these genes are implicated in neuronal development/function or metabolite transport/transformation. …”
Enlace del recurso
Enlace del recurso

“…There were no differences between treatment groups in the Matsuda index or HBA1c or any secondary outcome measures. Interestingly, weight loss in both groups correlated significantly with decreases in subcutaneous, but not visceral adipose tissue measured by MRI. …”
Enlace del recurso
Enlace del recurso

“…DISCUSSION: Environmental features seem to be more accurate than GMV in predicting both social and occupational outcomes in CHR. Interestingly, the predictions of follow up social and occupational outcomes rely on different patterns of occurrence of specific environmental adverse events, thus providing novel insights about how environmental adjustment disabilities, bullying and traumatic premorbid experiences may impact on different bad outcomes associated with the CHR status.…”
Enlace del recurso
Enlace del recurso

“…To help verify the potential latch for the Down state protomer, we conducted some preliminary molecular dynamic simulations that effectively turn off this specific latch glue point via a single point mutation of GLN564. Interestingly, the single point mutation lead to the latch releasing in less than a few nanoseconds, but the latch remained fixed in the wild state protomer for up to 0.1 microseconds that were simulated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The expression of PD-L1 was significantly higher on IC versus TC (p < 0.0001) and was clinicopathologic-independent (p > 0.05) except higher level of PD-L1(+)TC in the endometrioid versus mucinous tumours. Interestingly, blood-circulating sPD-L1 positively correlated with PD-L1(+)M-MDSCs (p = 0.03) and PD-L1(+)MO/MA (p = 0.02) in the blood but not with these cells in the ascites and tumours nor with PD-L1(+)TC/IC (each p > 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…High Aurora A expression was remarkably and significantly associated with overall survival (OS) (8-year OS ratio: 69.5% vs 81.1%, OR=1.76, 95% CI: 1.03~3.02, P=0.041) in obesity cohort. Interestingly, higher expression of Aurora A was not associated with a shorter overall survival time among the non-obesity breast cancer (8-year OS ratio: 81.4% vs 85.8%, OR=1.40, 95% CI: 0.79~2.45, P=0.229). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, via its proline rich domain, RIN3 recruited BIN1(bridging integrator 1) and CD2AP (CD2 associated protein), two other AD risk factors, to early endosomes. Interestingly, overexpression of RIN3 or CD2AP promoted APP cleavage to increase its carboxyl terminal fragments (CTFs) in PC12 cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To foster its mission, NAMDC has implemented a comprehensive Mitochondrial Disease Clinical Registry (hereafter NAMDC Registry), collected biosamples deposited into the NAMDC Biorepository, defined phenotypes and genotypes of specific disorders, collected natural history data, identified outcome measures, characterized safety and long-term toxicity and efficacy of promising therapies, and trained young investigators interested in patient-oriented research in mitochondrial disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cancer in general was detected in 10/271, prevalence of 0.7% (95% CI: 0.3–1.2) over the same period. Interestingly, diabetes was not noted in the study group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The volumetric PET parameters whole-body MTV and whole-body TLG as well as the standard uptake value (SUV) peak were quantified using 50%-isocontour volumes of interests (VOIs) and then correlated with the serologic parameters lactate dehydrogenase (LDH), S-100 protein, c-reactive protein (CRP) and alkaline phosphatase (AP). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the intermediate and favorable groups, CR rates was 76.5% (163/213), 86.9% (506/582) and 86.1% (68/79) in different doses of IDA (P=0.007). Interestingly, IA regimen with IDA 10 mg/m(2) was the only beneficial factor affecting CR in this group after adjusted for age, blast ratio of bone marrow and FAB classification[OR=0.47 (95% CI 0.31–0.71), P<0.001]. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our ultra-deep CSF profiling of 20 cases uncovered the majority of previously reported AD biomarker candidates, most of which, however, displayed no statistical significance except SMOC1 and TGFB2. Interestingly, the AD CSF showed evident decrease of a large number of mitochondria proteins that were only detectable in our ultra-deep analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso