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266261por Drakos, Stefanos, Chatzantonis, Grigorios, Bietenbeck, Michael, Evers, Georg, Schulze, Arik Bernard, Mohr, Michael, Fonfara, Helena, Meier, Claudia, Yilmaz, Ali“…However, SARS-CoV-2 can directly infect vascular endothelium and subsequently cause vascular inflammation, atherosclerotic plaque instability and thereby result in both endothelial dysfunction and myocardial inflammation/infarction. Interestingly, up to 50% of patients suffer from persistent exercise dyspnoea and a post-viral fatigue syndrome (PVFS) after having overcome an acute COVID-19 infection. …”
Publicado 2021
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266262por Kudura, Ken, Dimitriou, Florentia, Basler, Lucas, Förster, Robert, Mihic-Probst, Daniela, Kutzker, Tim, Dummer, Reinhard, Mangana, Joanna, Burger, Irene A., Kreissl, Michael C.“…Age and female sex were also found to be negative predictive biomarkers with lower predictive power. Interestingly, total tumor volume at TP 0 and number of metastases at TP 0 as well as the occurrence of early immune-related adverse events between TP 0 and TP 2 did not have any predictive value for early treatment response. …”
Publicado 2021
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266263por Silvas, Jesus A., Vasquez, Desarey Morales, Park, Jun-Gyu, Chiem, Kevin, Allué-Guardia, Anna, Garcia-Vilanova, Andreu, Platt, Roy Neal, Miorin, Lisa, Kehrer, Thomas, Cupic, Anastasija, Gonzalez-Reiche, Ana S., van Bakel, Harm, García-Sastre, Adolfo, Anderson, Tim, Torrelles, Jordi B., Ye, Chengjin, Martinez-Sobrido, Luis“…However, growth kinetics of ΔORF viruses were like those of rSARS-CoV-2/WT. Interestingly, infection of K18 human angiotensin-converting enzyme 2 (hACE2) transgenic mice with the ΔORF rSARS-CoV-2s identified ORF3a and ORF6 as the major contributors of viral pathogenesis, while ΔORF7a, ΔORF7b, and ΔORF8 rSARS-CoV-2s induced pathology comparable to that of rSARS-CoV-2/WT. …”
Publicado 2021
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266264por El-Raghi, Ali Ali, Hassan, Mahmoud A. E., El-Ratel, Ibrahim T., Hashem, Nesrein M., Abdelnour, Sameh A.“…Likewise, does with dead twins and triplets kids had 2.566 and 2.138 times, respectively higher odds of culling compared to those with singles. Interestingly, culling risk decreased with 74.6% (OR = 0.254), 79.8% (OR = 0.202), and 75.6% (OR = 0.244) in does with TMY, LP, and DMY more than 230 kg, 260 days, and 0.800 kg, respectively compared to their counterparts (less than 185 kg, 240 day, and 0.500 kg, respectively). …”
Publicado 2021
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266265por Zhang, Lu, McLeod, Howard L, Liu, Ke-Ke, Liu, Wen-Hui, Huang, Hang-Xing, Huang, Ya-Min, Sun, Shu-Sen, Chen, Xiao-Ping, Chen, Yao, Liu, Fang-Zhou, Xiao, Jian“…The pain interference on patients' general activity, mood, relationships with others, and interests was reduced, but the difference was not statistically significant compared with the control group (Ps=.10-.76). …”
Publicado 2021
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266266Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritispor Gupta, Vinod K., Cunningham, Kevin Y., Hur, Benjamin, Bakshi, Utpal, Huang, Harvey, Warrington, Kenneth J., Taneja, Veena, Myasoedova, Elena, Davis, John M., Sung, Jaeyun“…RESULTS: We found age to be the largest determinant of the overall compositional variance in the gut microbiome (R(2) = 7.7%, P = 0.001, PERMANOVA). Interestingly, the next factor identified to explain the most variance in the gut microbiome was MCII status (R(2) = 3.8%, P = 0.005). …”
Publicado 2021
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266267por Jalkanen, Kari, Järvenpää, Riia, Tilles-Tirkkonen, Tanja, Martikainen, Janne, Aarnio, Emma, Männikkö, Reija, Rantala, Eeva, Karhunen, Leila, Kolehmainen, Marjukka, Harjumaa, Marja, Poutanen, Kaisa, Ermes, Miikka, Absetz, Pilvikki, Schwab, Ursula, Lakka, Timo, Pihlajamäki, Jussi, Lindström, Jaana“…The communication channel reaching the largest percentage of interested and eligible men (1353/3979, 34%) was relatives or friends. …”
Publicado 2021
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266268“…RESULTS: Therapists responded positively to the visual measures displayed by ARCADE, and how information changed based on proximity. Interestingly, they were able to combine multiple measures to assess patients’ performance and uncover hidden information that is not visible by the human eye (e.g. joint angles and compensation movements). …”
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266269“…Several subpopulations had evidence of LC3-II and contained degenerated mitochondrial components in the S-EV fraction, signaling to the existence of autophagy-related S-EVs. Interestingly, the S-EV fraction contained a MitoTracker-positive subpopulation, which was inhibited by the respiration inhibitor antimycin A, indicating the presence of mitochondria with membrane potential. …”
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266270por Cimba, M.J., Giannakopoulos, H., Day, S.T., Rose, M.J., Lee, K.C., Chuang, S-K., Ford, B.P.“…This was largely driven by parallel decreases in the number of unintentional injury mechanisms, such as motor vehicle collisions. Interestingly, there was a paradoxical increase in the number of intentional interpersonal injuries [1]. …”
Publicado 2021
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266271por Liu, Dengying, Chen, Zhenliang, Zhao, Wei, Guo, Longyu, Sun, Hao, Zhu, Kai, Liu, Guanglei, Shen, Xiuping, Zhao, Xiaoduo, Wang, Qishan, Ma, Peipei, Pan, Yuchun“…Annotation of the regions harbouring clustered |iHS| signals and candidate regions for ROH revealed a panel of interesting candidate genes associated with adaptation and economic traits, such as IL22RA1, CALHM3, ITGA9, NDUFB3, RGS3, SOD2, SNRPA1, ST3GAL4, ALAD, EXOSC10, and MASP2. …”
Publicado 2021
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266272por Trimmel, Helmut, Egger, Alexander, Doppler, Reinhard, Beywinkler, Christoph, Voelckel, Wolfgang G., Kreutziger, Janett“…Thus, inhaled analgesics could represent an interesting alternative. A mixture of 50% nitrous oxide and 50% oxygen (N(2)O, Livopan®) has been available in Germany and Austria for several years; however, prehospital use of Livopan has been merely realized and only one trial has been published. …”
Publicado 2021
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266273por Gitlin, Laura N., Marx, Katherine, Piersol, Catherine Verrier, Hodgson, Nancy A., Huang, Jin, Roth, David L., Lyketsos, Constantine“…TAP assessed PLWD abilities/interests, instructed caregivers in using prescribed activities, and provided dementia education and stress reduction techniques. …”
Publicado 2021
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266274por Ivankova, Nataliya V, Rogers, Laura Q, Herbey, Ivan I, Martin, Michelle Y, Pisu, Maria, Pekmezi, Dorothy, Thompson, Lieu, Schoenberger-Godwin, Yu-Mei M, Oster, Robert A, Fontaine, Kevin, Anderson, Jami L, Kenzik, Kelly, Farrell, David, Demark-Wahnefried, Wendy“…The receipt of regular feedback about progress was noted as encouragement toward goal achievement, whereas women were particularly interested in receiving immediate feedback to stay motivated. …”
Publicado 2021
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266275por Shrestha, Shakti, Poudel, Arjun, Cardona, Magnolia, Steadman, Kathryn J., Nissen, Lisa M.“…Literature was searched on PubMed, EMBASE, CINAHL, PsycINFO and Google Scholar until December 2019 for studies on deprescribing intervention with a control group (with or without randomisation); targeting ⩾65-year olds, at EOL, with at least one life-limiting illness and at least one potentially inappropriate DPM. We were interested in any patient-related outcomes. Studies with similar outcome assessment criteria were subjected to meta-analysis and narrative synthesis otherwise. …”
Publicado 2021
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266276por Ramakrishna, Satish“…The calculation in this paper has interesting implications for the interpretation of the Wigner’s friend experiment, as well as the Mott experiment, which is explored in “Connection to some general theoretical results” and “Recurrence times” (especially the enumerated points in “Recurrence times”). …”
Publicado 2021
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266277por Cuchillo-Ibañez, Inmaculada, Lennol, Matthew P., Escamilla, Sergio, Mata-Balaguer, Trinidad, Valverde-Vozmediano, Lucía, Lopez-Font, Inmaculada, Ferrer, Isidro, Sáez-Valero, Javier“…In extracts from subjects with AD-related pathology, the levels of LRP3 mRNA and protein were lower than those in MA subjects. Interestingly, LRP3 transfection in CHO-PS70 cells induced a decrease of full-length APP levels and APP-CTF, particularly in the membrane fraction. …”
Publicado 2021
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266278por Lücht, Jana, Rolfs, Nele, Wowro, Sylvia J., Berger, Felix, Schmitt, Katharina R. L., Tong, Giang“…In the reperfusion phase, TNF-α and MCP-1 gene expressions were increased, and cooling was associated with significantly lower TGFβ gene expression. Interestingly, cooled Normoxia groups had significant upregulations of microglial activation marker, Iba1, IL-1β, and TNF-α gene expressions. …”
Publicado 2021
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266279por Herbemont, C., Labrosse, J., Bennani-Smires, B., Cedrin-Durnerin, I., Peigne, M., Sermondade, N., Sarandi, S., Vivot, A., Vicaut, E., Talib, Z., Grynberg, M., Sifer, C.“…Furthermore, recent meta-analyses concluded with low evidence to a superiority of hypoxia on IVF/ICSI outcomes. Interestingly, a study on mice embryos suggested that oxidative stress (OS) might only have an adverse impact on embryos at cleavage stage. …”
Publicado 2021
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266280“…The overexpression of STAT3 could reverse miR-365a-3p or circNOLC1 depletion-inhibited proliferation and cancer stem cell properties of breast cancer. Interestingly, the expression of circNOLC1 and STAT3 was repressed by the treatment of propofol. …”
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