“…Eligible patients were 18 to 89 years of age, had a diagnosis of type 2 diabetes, hemoglobin A1c (HbA1c) ≥8% and <12% in the past 3 months, an active online patient portal account (tied to the electronic health record), and access to an iOS or Android smartphone. Interested patients were emailed a baseline survey, and once this was completed, were sent instructions for downloading the Time2Focus app. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MAIN OUTCOMES AND MEASURES: The outcomes of interests were quarterly state-level mortality from drug overdoses, known indicators for prescription opioid abuse and doctor shopping, MAT, and prevalence of drug overdose and opioid use disorder. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These can include the presence of larger polyps or the location of a polyp in an area that makes removal technically challenging or high risk.A particularly challenging situation arises when after extensive effort there is still polyp tissue remaining that cannot be removed using routine techniques. We are interested in exploring a technique which involves the placement of a rubber band after sucking a small area of the colon lining into a cap loaded onto the tip of the colonoscope. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We used group-based trajectory modelling to identify latent trajectory groups for eGFR. We were interested in the group with deteriorating kidney function (the high-risk group). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As expected, we observed lower total fat mass in FPLD2 patients compared to nFPLD (15.8±9.3 kg vs. 28.5±12.4 kg, p=0.001), as well as lower fat mass in regions of arms, legs and trunk. Interestingly, patients with FPLD2 showed lower bone mineral density (BMD) compared to nFPLD 1.0±0.2 g/cm(3) vs 1.2±0.1 g/cm(3), p=0.01) and lower t-score (0.2±1.8 vs.1.5±1.2). …”
Enlace del recurso
Enlace del recurso

“…Newly formed spongy fibrovascular cartilaginous tissue (with viable chondrocytes within the lacunae) was also noted in processed cartilage-filled 3D-P4HB groups. Interestingly, 3D-P4HB (rebar) scaffolds demonstrated the fastest material absorption overtime, as demonstrated by biomechanical testing and SEM analysis which verified widespread pitting on the material surface. …”
Enlace del recurso
Enlace del recurso

“…To provide mechanistic insight into lncRNA regulation by TGFβ signaling, SMAD2/3 ChIp-Seq data from BT-549 TNBC model retrieved from Gene Expression Omnibus (GEO) revealed direct binding of SMAD2/SMAD3 to the promoter of AC112721.1, AC112721.2, MALAT1, HHIP-AS1, LINC00472, and SLC7A11, suggesting their direct regulation by TGFβ1/SMAD2/SMAD3 pathway. Interestingly, AC112721.1, AC112721.2 exhibited higher expression in TNBC compared to normal breast tissue suggesting a possible role for those lncRNA in TNBC biology. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As observed in prior reports of patients from the general population, the presence of comorbidities, age, BUN and hypoxia at presentation are highly predictive of mortality in this setting. Interestingly, serum albumin appears to be an important predictor in patients with cancer, as are cancer-specific covariates including tumor type and metastatic status. …”
Enlace del recurso
Enlace del recurso

“…Exclusively through web registration, Stomp Out Stroke participants (aged >18 years) detailed sociodemographic characteristics, family history of stroke, and stroke survivorship. Participant health interests were compared by race or ethnicity using Kruskal-Wallis or chi-square test at an α=.05. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All PET-positive patients were previously treated with a high dose of steroids and intravenous immunoglobulin prior to PET/CT had elevated serum cTnI except for one patient for whom PET/CT was delayed several days. Interestingly, in 5/6 (83%) patients who presented with concomitant myositis, pathological uptake was seen on whole-body (68)Ga-DOTATOC PET/CT images in the skeletal muscles, suggesting an additional advantage of this method to assess the full extent of the disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A Bayesian molecular clock analysis established the most recent common ancestor in 1964 (95% HPD interval=1961.975-1966.218) and corroborated a CC5 expansion event starting in Chile in 1999 (Fig. 3). Interestingly, our analyses revealed two branches within the ST5-SCCmecI lineage: one predominating in 1999-2006, and a more recent branch (related to the ST105-SCCmecII clone) that emerged around 2008. …”
Enlace del recurso
Enlace del recurso

“…Moreover, the FWLS/SLS ratio was significantly lower in the SF subgroup (0.92±0.09 vs 0.97±0.08, p<0.01). Interestingly, P-CA athletes with SF experienced fatigue (17 vs 34%, p<0.05) or chest pain (0 vs 15%, p=N/A) less frequently during the course of the infection; however, the presence of a mild pericardial effusion was more common (41 vs 12%, p<0.01). …”
Enlace del recurso
Enlace del recurso

“…When compared to uninjured side, DTFS area and volumetric measurements were significantly increased in injured sides of patients with suspected SSI, including medial gutter volumes, consistent with associated deltoid ligament instability. However, interestingly, we observed a diagnostic accuracy for WBCT area and volumetric measurements to be lower than initially expected. …”
Enlace del recurso
Enlace del recurso

“…We felt this case was interesting as the patient described demonstrated a good response to colchicine and highlighted the difficulties that can present in making the diagnosis. …”
Enlace del recurso
Enlace del recurso

“…CASE REPORT - INTRODUCTION: An interesting case of an 11-year recurrent isolated lateral rectus myositis. …”
Enlace del recurso
Enlace del recurso

“…CASE REPORT - CASE DESCRIPTION: Interestingly he first presented with fever and cervical lymphadenopathy at 13 years of age to local hospital, when a biopsy had revealed lymphoma but the diagnosis was changed to SLE following review at tertiary hospital. …”
Enlace del recurso
Enlace del recurso

“…No significant difference was found between PD-L1 expression, Mayo stages, and histological type, manifesting that checkpoint inhibitors might be effective for tumors of both early and late stages, as well as with different histological types. Interestingly, we found that the average number of tertiary lymphoid structures (TLS) per slide tended to be higher in tumors with deficient mismatch repair (dMMR) that are promising candidates for immunotherapy, and tumors with higher number of TLS tended to have longer OS and DFS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, it is well-known that in the active-site cavities of enzymes the dielectric constant, compared with bulk water, is reduced; therefore, we have summarized and discussed the effect of a change in solvent polarity on the stability and structure of binary and ternary complexes: Opposite effects on charged O sites and neutral N sites are observed, and this leads to interesting insights.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Principal coordinate analysis indicated converging phyllomicrobiome profiles on rice genotypes sharing the same agroclimatic zone. Interestingly, the rice genotype grown in the contrasting zones displayed divergent phyllomicrobiomes suggestive of the role of environment on phyllomicrobiome assembly. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Morphological changes in 3D cultures were observed as cell stretching, cell–cell, and cell–ECM interactions associated with a loss of polarity and reorganization on bulk structures. Interestingly, we found prolongations of the cytoplasmic membrane of Hs578T cells similar to tunneled nanotubes contacting between neighboring cells, suggesting the existence of cellular intercommunication processes and the possibility of fusion between spheroids. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso