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2021por Peng, Li, Oganesyan, Vaheh, Wu, Herren, Dall’Acqua, William F, Damschroder, Melissa M“…Anifrolumab (anifrolumab) is an antagonist human monoclonal antibody that targets interferon α receptor 1 (IFNAR1). Anifrolumab has been developed to treat autoimmune diseases and is currently in clinical trials. …”
Publicado 2015
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2022
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2023por Hartung, Hans-Peter, Kappos, Ludwig, Goodin, Douglas S., O’Connor, Paul, Filippi, Massimo, Arnason, Barry, Comi, Giancarlo, Cook, Stuart, Jeffery, Douglas, Petkau, John, White, Richard, Bogumil, Timon, Beckmann, Karola, Stemper, Brigitte, Suarez, Gustavo, Sandbrink, Rupert, Pohl, Christoph“…This regression analysis of patients with relapsing–remitting MS from BEYOND examined the predictive value of patient characteristics at baseline and after 1 year of treatment with interferon beta-1b 250 μg every other day for clinical and MRI outcomes after year 1 of the study. 857 and 765 patients were included in the analyses of clinical and MRI outcomes, respectively. …”
Publicado 2015
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2024por Woods, Katherine, Schittenhelm, Ralf B, Heesterbeek, Dani, Knights, Ashley, Anaka, Matthew, Purcell, Anthony W, Behren, Andreas, Cebon, JonathanEnlace del recurso
Publicado 2015
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2025“…We orally administered P. ginseng extracts or ginsenosides to wild-type (WT) C57BL/6 (B6) and BALB/c mice and to B6 mice deficient in either recombination activating gene 2 (RAG-2) or interferon-γ (IFN-γ). We then tested the cytotoxic activity of NK cells (of spleen and liver mononuclear cells) against NK-sensitive YAC-1 cells. …”
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2026
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2027por Li, Jian, Chen, Jin-Na, Zeng, Ting-Ting, He, Fan, Chen, Shu-Peng, Ma, Stephanie, Bi, Jiong, Zhu, Xiao-Feng, Guan, Xin-Yuan“…CD133(+) CSCs have been reported to resist conventional chemo- and radiotherapy, but little is known about their response to immune surveillance. Interferon-gamma (IFN-γ) is one of key cytokines that the immune system produce to eradicate cancer cells, so we investigated the function of IFN-γ on CD133+ HCC CSCs in this study. …”
Publicado 2016
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2028por Eldar-Yedidia, Yifat, Bar-Meir, Maskit, Hillel, Miriam, Abitbol, Guila, Broide, Eti, Falk, Roni, Assous, Marc, Schlesinger, YechielEnlace del recurso
Publicado 2016
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2029
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2030por Oji, Satoru, Nicolussi, Eva-Maria, Kaufmann, Nathalie, Zeka, Bleranda, Schanda, Kathrin, Fujihara, Kazuo, Illes, Zsolt, Dahle, Charlotte, Reindl, Markus, Lassmann, Hans, Bradl, Monika“…In contrast to multiple sclerosis (MS) patients who benefit from therapies involving type I interferons (I-IFN), NMO patients typically do not profit from such treatments. …”
Publicado 2016
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2031por Donovan, JeffEnlace del recurso
Publicado 2015
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2032por Bourgeois-Daigneault, Marie-Claude, Roy, Dominic Guy, Falls, Theresa, Twumasi-Boateng, Kwame, St-Germain, Lauren Elizabeth, Marguerie, Monique, Garcia, Vanessa, Selman, Mohammed, Jennings, Victoria Ann, Pettigrew, Jessica, Amos, Sally, Diallo, Jean-Simon, Nelson, Brad, Bell, John Cameron“…From a therapeutic point of view, the interferon-γ virus slowed tumor growth, minimized lung tumors, and prolonged survival in several murine tumor models. …”
Publicado 2016
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2033“…Here, we show that type I interferon (IFN) induction but not its downstream signaling is blocked by HBV replication in HepG2.2.15 cells. …”
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2034por Körber, Inken, Katayama, Shintaro, Einarsdottir, Elisabet, Krjutškov, Kaarel, Hakala, Paula, Kere, Juha, Lehesjoki, Anna-Elina, Joensuu, Tarja“…Of these, 33 genes were identified by both methods. Several interferon-regulated genes were weaker expressed in Cstb(-/-) microglia compared to control. …”
Publicado 2016
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2035por Jung, Hye Jin, Kim, Young-Ho, Kim, You Sun, Jeong, Seong Yeon, Park, Sung Won, Seo, Ji Yeon, Jung, Hyemi, Im, Jong Pil, Kim, Ji Won, Hong, Sung Noh, Lee, Kuk Lae“…Intestinal tuberculosis (ITB) remains prevalent in Asia. An interferon-γ assay (QuantiFERON-TB gold test [QFT]) is considered to be an effective supplementary tool for diagnosing ITB. …”
Publicado 2016
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2036por Ratinier, Maxime, Shaw, Andrew E., Barry, Gerald, Gu, Quan, Di Gialleonardo, Luigina, Janowicz, Anna, Varela, Mariana, Randall, Richard E., Caporale, Marco, Palmarini, Massimo“…In addition, NS4 confers a replication advantage on the virus in interferon (IFN)-competent primary sheep endothelial cells and immortalized cell lines. …”
Publicado 2016
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2037por Pruetpongpun, Nattapol, Khawcharoenporn, Thana, Damronglerd, Pansachee, Suthiwartnarueput, Worapop, Apisarnthanarak, Anucha, Rujanavej, Sasinuch, Suwantarat, Nuntra“…Anti-interferon (IFN)-γ autoantibodies are increasingly recognized as a cause of adult-onset immunodeficiency and increased risk for infections with intracellular pathogens. …”
Publicado 2016
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2038“…There are limited data on interferon-γ release assay (IGRA) performance in young children, which our research aims to address by investigating the usefulness of IGRA for the diagnosis of LTBI. …”
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2039por Afarid, Mehrdad, Lashkarizadeh, Hamid, Ashraf, Mohammad J, Nowroozzadeh, Mohammad Hossein, Shafiee, Sayed M“…PURPOSE: To study the efficacy of intravitreal interferon alpha-2b for endotoxin-induced uveitis. MATERIALS AND METHODS: A total of 36 rabbits were randomly allocated to one of the three groups: (1) received interferon plus balanced-salt solution; (2) received lipopolysaccharide (LPS) plus interferon; and (3) received LPS plus balanced-salt solution. …”
Publicado 2016
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2040por Cook, Bradley W. M., Ranadheera, Charlene, Nikiforuk, Aidan M., Cutts, Todd A., Kobasa, Darwyn, Court, Deborah A., Theriault, Steven S.Enlace del recurso
Publicado 2016
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