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2181“…Interferon gamma (IFN-γ) is a pleiotropic lymphokine produced by T-lymphocytes which acts as a soluble mediator in immunological reactions. …”
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2182por Yi, Yue, Wang, Chengdong, Xu, Zhiwen, Li, Desheng, Zhu, Ling, Li, Fengqin, Qi, Xinqiao, Guo, WanzhuEnlace del recurso
Publicado 2012
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2183por Hoegen, Bärbel, Saalmüller, Armin, Röttgen, Marlene, Rziha, Hanns-Joachim, Geldermann, Hermann, Reiner, Gerald, Pfaff, Eberhard, Büttner, Mathias“…In Chinese Meishan/German Landrace cross-bred swine F(2) generation interferon gamma (IFN-γ) production by peripheral blood mononuclear cells (PBMC) was determined directly ex vivo at different time points after survival of a virulent pseudorabies virus (PRV) infection. …”
Publicado 2004
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2184
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2185por Spiegel, Martin, Pichlmair, Andreas, Mühlberger, Elke, Haller, Otto, Weber, Friedemann“…In this study, we demonstrated that multiplication of SARS-CoV in cell culture can be strongly inhibited by pretreatment with interferon-beta. Interferon-alpha and interferon-gamma, by contrast, were less effective. …”
Publicado 2004
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2186
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2187“…Mouse hepatitis viruses (MHV) of different virulence for mice were studied with respect to interferon (IFN) sensitivity. The growth of low-virulent MHV-S and intermediately virulent MHV-JHM was significantly suppressed in IFN-treated L cells compared with untreated cells. …”
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2188“…In a double-blind, placebo-controlled study, self-administered intranasal interferonα-2a or placebo was given both before and after challenge with respiratory syncytial virus. …”
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2189por Rocha-de-Lossada, Carlos, Alba-Linero, Carmen, Borroni, Davide, Rachwani-Anil, Rahul, Zamorano-Martín, Francisco, Rodríguez-Calvo-de-Mora, MarinaEnlace del recurso
Publicado 2020
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2190
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2191por Terczynska-Dyla, Ewa, Bibert, Stephanie, Duong, Francois H.T., Lauber, Chris, Gad, Hans Henrik, Kaderali, Lars, Heim, Markus H., Bochud, Pierre-Yves, Hartmann, Rune“…IFNL4, a recently discovered member of the interferon λ family (IFNλs or type III IFNs), is a pseudogene in a significant fraction of the human population. …”
Publicado 2015
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2192por Selvaggi, Carla, Pierangeli, Alessandra, Fabiani, Marco, Spano, Lucia, Nicolai, Ambra, Papoff, Paola, Moretti, Corrado, Midulla, Fabio, Antonelli, Guido, Scagnolari, Carolina“…OBJECTIVES: The airway expression of type III interferons (IFNs) was evaluated in infants hospitalized for respiratory syncytial virus (RSV) or rhinovirus (HRV) bronchiolitis. …”
Publicado 2014
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2193“…Interference of interferon response was confirmed by reporter assays involving different interferon inducible promoters, qRT PCR, ELISA, and immunofluorescence microscopy. …”
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2194por Li, Yuanyuan, Song, Yueqi, Zhu, Leqing, Wang, Xiao, Richers, Brittany, Leung, Donald Y. M., Bin, Lianghua“…Type I interferon kappa (IFNκ) is selectively expressed in human keratinocytes. …”
Publicado 2020
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2195por Lee, Cheryl Yi‐Pin, Carissimo, Guillaume, Chen, Zheyuan, Lum, Fok‐Moon, Abu Bakar, Farhana, Rajarethinam, Ravisankar, Teo, Teck‐Hui, Torres‐Ruesta, Anthony, Renia, Laurent, Ng, Lisa FP“…Transient inhibition of the type I interferon (IFN) pathway through the use of an IFNAR1‐blocking antibody, MAR1‐5A3, could efficiently permit active virus replication in immunocompetent animals. …”
Publicado 2020
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2196por Schögler, Aline, Stokes, Andrea B., Casaulta, Carmen, Regamey, Nicolas, Edwards, Michael R., Johnston, Sebastian L., Jung, Andreas, Moeller, Alexander, Geiser, Thomas, Alves, Marco P.“…There is growing evidence suggesting the involvement of the interferon (IFN) pathway in RV-associated morbidity in asthma and COPD. …”
Publicado 2016
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2197“…Results: Our findings showed the acidic pH in the range of 2-3 is more suitable than alkaline pH >12 for solubilization and achieving higher content of interferon β-1beta and pure recombinant protein. We have also demonstrated that 1% SDS acts better than 2M urea to solubilize Inclusion body proteins of interferon β-1b at pH of 2-3. …”
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2198“…Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. …”
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2199por Mantlo, Emily, Bukreyeva, Natalya, Maruyama, Junki, Paessler, Slobodan, Huang, Cheng“…Herein, we report the remarkable sensitivity of SARS-CoV-2 to recombinant human interferons α and β (IFNα/β). Treatment with IFN-α or IFN-β at a concentration of 50 international units (IU) per milliliter drastically reduce viral titers by 3.4 log or 4.5 log, respectively in Vero cells. …”
Publicado 2020
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2200“…The objective of this study was to determine the long-term effects of fetal alcohol exposure on the production of interferon-ϒ (IFN-ϒ), a cytokine known to regulate both innate and adaptive immunity. …”
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