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  1. 2201
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    Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone
  2. 2202
    “…We investigated whether HCQ in association with interferon-ω (IFN-ω) is effective for FIPV in vitro. …”
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    Antiviral Effects of Hydroxychloroquine and Type I Interferon on In Vitro Fatal Feline Coronavirus Infection
  3. 2203
    “…OBJECTIVE: To investigate the possibility of combining tuberculosis (TB)-interferon (IFN)-γ release assays (IGRAs) with lymphocyte enumeration for diagnosis of Mycobacterium tuberculosis infection. …”
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    Combining interferon-γ release assays with lymphocyte enumeration for diagnosis of Mycobacterium tuberculosis infection
  4. 2204
    “…The pathogenesis underlying AHF is poorly understood; however, a prolonged, elevated interferon-α (IFN-α) response is associated with a negative disease outcome. …”
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    Type I interferon underlies severe disease associated with Junín virus infection in mice
  5. 2205
    “…Our findings show the anti-JEV activities of swine interferon-inducible transmembrane proteins and broaden the antiviral spectrum of IFITM protein family. …”
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    S-palmitoylation of swine interferon-inducible transmembrane protein is essential for its anti-JEV activity
  6. 2206
    “…[Image: see text] Interferons are commonly utilized in the treatment of chronic hepatitis B virus (HBV) infection but are not effective for all patients. …”
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    Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line
  7. 2207
    “…The ubiquitin-like modifier ISG15 (interferon-stimulated gene 15) is induced by interferons, bacterial and viral infection, and DNA damage, but it is also constitutively expressed in many types of cancer, although its role in tumorigenesis is still largely elusive. …”
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    Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage
  8. 2208
    “…A distinct phenotype was observed in severe and critical patients, consisting of a highly impaired interferon (IFN) type I response (characterized by no IFN-β and low IFN-α production and activity), which was associated with a persistent blood viral load and an exacerbated inflammatory response. …”
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    Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
  9. 2209
    “…Recurrent somatic mutations in host genes have exposed the T-cell receptor pathway through nuclear factor κB to interferon regulatory factor 4 (IRF4) as an essential driver for this malignancy. …”
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    Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma
  10. 2210
    por Enc, Feruze, Ulasoglu, Celal
    Publicado 2020
    “…In this report, we present a 44 years old man who was diagnosed as autoimmune hepatitis (AIH) following the treatment of HBV+HDV hepatitis with pegylated interferon (PegIFN). He presented with complaint of fatigue. …”
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    A case of autoimmune hepatitis following pegylated interferon treatment of chronic hepatitis delta
  11. 2211
    “…PURPOSE: We aimed to analyze and evaluate the safety signals of ribavirin-interferon combination through data mining of the US Food and Drug Administration Adverse Event Reporting System (FAERS), so as to provide reference for the rationale use of these agents in the management of relevant toxicities emerging in patients with novel coronavirus pneumonia (COVID-19). …”
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    Assessment of the Potential Adverse Events Related to Ribavirin-Interferon Combination for Novel Coronavirus Therapy
  12. 2212
    “…Type 1 interferons plays a major role in the CD8 T-cell response to viral infection. …”
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    Evolutionary Pattern of Interferon Alpha Genes in Bovidae and Genetic Diversity of IFNAA in the Bovine Genome
  13. 2213
    “…Nebulized gamma interferon (IFN-γ) protein has been studied for clinical safety and efficacy against pulmonary tuberculosis (TB). …”
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    Transient Transfection of the Respiratory Epithelium with Gamma Interferon for Host-Directed Therapy in Pulmonary Tuberculosis
  14. 2214
    “…BACKGROUND: Neutralizing anti-drug antibodies (NAbs) to interferon beta (IFNβ) develop in up to 47% of multiple sclerosis (MS) treated patients inhibiting treatment effect of IFNβ. …”
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    Long-Term Consequences of High Titer Neutralizing Antibodies to Interferon-β in Multiple Sclerosis
  15. 2215
    “…The results showed that prior to vaccination, IL-8 was expressed at the highest levels, with at least 200-fold greater expression compared to other cytokines, while CD8 mRNA expression was significantly higher than CD4 mRNA expression level. Interferon-γ was up-regulated at both 4- and 8-weeks post-vaccination while IL-8 was down-regulated at 8-weeks post-vaccination.…”
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    Koalas vaccinated against Koala retrovirus respond by producing increased levels of interferon-gamma
  16. 2216
    “…While inhibition of T cell co-inhibitory receptors has revolutionized cancer therapy, the mechanisms governing their expression on human T cells have not been elucidated. Type 1 interferon (IFN-I) modulates T cell immunity in viral infection, autoimmunity, and cancer, and may facilitate induction of T cell exhaustion in chronic viral infection(1,2). …”
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    Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
  17. 2217
    por Ma, Yuanlin, Su, Xin-zhuan, Lu, Fangli
    Publicado 2020
    “…Many parasite infections, including infections of protozoa and helminths, can inhibit inflammatory responses and impact disease outcomes caused by viral, bacterial, or other parasitic infections. Type I interferon (IFN-I) has been recognized as an essential immune effector in the host defense against various pathogens. …”
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    The Roles of Type I Interferon in Co-infections With Parasites and Viruses, Bacteria, or Other Parasites
  18. 2218
    “…OBJECTIVES: Anti-type I interferon (IFN) autoantibodies have been reported in patients with systemic lupus erythematosus (SLE). …”
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    Association between anti-interferon-alpha autoantibodies and COVID-19 in systemic lupus erythematosus
  19. 2219
    “…BACKGROUND: Colon adenocarcinoma (COAD) is one of the most common malignant tumors and has high incidence and mortality rates. The interferon regulatory factor (IRF) family is known as a key transcription factor in the IFN signaling pathway and cellular immunity. …”
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    Identification of the Prognostic Value and Clinical Significance of Interferon Regulatory Factors (IRFs) in Colon Adenocarcinoma
  20. 2220
    “…Mammalian first line of defense against viruses is accomplished by the interferon (IFN) system. Viruses have evolved numerous mechanisms to reduce the IFN action allowing them to invade the host and/or to establish latency. …”
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    Synthetic rewiring and boosting type I interferon responses for visualization and counteracting viral infections
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