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2201por Owen, Katie L, Gearing, Linden J, Zanker, Damien J, Brockwell, Natasha K, Khoo, Weng Hua, Roden, Daniel L, Cmero, Marek, Mangiola, Stefano, Hong, Matthew K, Spurling, Alex J, McDonald, Michelle, Chan, Chia‐Ling, Pasam, Anupama, Lyons, Ruth J, Duivenvoorden, Hendrika M, Ryan, Andrew, Butler, Lisa M, Mariadason, John M, Giang Phan, Tri, Hayes, Vanessa M, Sandhu, Shahneen, Swarbrick, Alexander, Corcoran, Niall M, Hertzog, Paul J, Croucher, Peter I, Hovens, Chris, Parker, Belinda SEnlace del recurso
Publicado 2020
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2202“…We investigated whether HCQ in association with interferon-ω (IFN-ω) is effective for FIPV in vitro. …”
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2203por Lv, Dingfeng, Liu, Yanqing, Guo, Fei, Wu, Aihua, Mo, Yijun, Wang, Shanshan, Chu, Jinguo“…OBJECTIVE: To investigate the possibility of combining tuberculosis (TB)-interferon (IFN)-γ release assays (IGRAs) with lymphocyte enumeration for diagnosis of Mycobacterium tuberculosis infection. …”
Publicado 2020
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2204por Hickerson, Brady T, Sefing, Eric J, Bailey, Kevin W, Van Wettere, Arnaud J, Penichet, Manuel L, Gowen, Brian B“…The pathogenesis underlying AHF is poorly understood; however, a prolonged, elevated interferon-α (IFN-α) response is associated with a negative disease outcome. …”
Publicado 2020
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2205por Xu, Zhao, Li, Xiaoling, Xue, Jichu, Shen, Lingyi, Zheng, Wenming, Yin, Sugai, Xu, Jun“…Our findings show the anti-JEV activities of swine interferon-inducible transmembrane proteins and broaden the antiviral spectrum of IFITM protein family. …”
Publicado 2020
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2206por Hodge, Kenneth, Makjaroen, Jiradej, Robinson, Jonathan, Khoomrung, Sakda, Pisitkun, Trairak“…[Image: see text] Interferons are commonly utilized in the treatment of chronic hepatitis B virus (HBV) infection but are not effective for all patients. …”
Publicado 2020
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2207Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakagepor Raso, Maria Chiara, Djoric, Nikola, Walser, Franziska, Hess, Sandra, Schmid, Fabian Marc, Burger, Sibylle, Knobeloch, Klaus-Peter, Penengo, Lorenza“…The ubiquitin-like modifier ISG15 (interferon-stimulated gene 15) is induced by interferons, bacterial and viral infection, and DNA damage, but it is also constitutively expressed in many types of cancer, although its role in tumorigenesis is still largely elusive. …”
Publicado 2020
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2208por Hadjadj, Jérôme, Yatim, Nader, Barnabei, Laura, Corneau, Aurélien, Boussier, Jeremy, Smith, Nikaïa, Péré, Hélène, Charbit, Bruno, Bondet, Vincent, Chenevier-Gobeaux, Camille, Breillat, Paul, Carlier, Nicolas, Gauzit, Rémy, Morbieu, Caroline, Pène, Frédéric, Marin, Nathalie, Roche, Nicolas, Szwebel, Tali-Anne, Merkling, Sarah H., Treluyer, Jean-Marc, Veyer, David, Mouthon, Luc, Blanc, Catherine, Tharaux, Pierre-Louis, Rozenberg, Flore, Fischer, Alain, Duffy, Darragh, Rieux-Laucat, Frédéric, Kernéis, Solen, Terrier, Benjamin“…A distinct phenotype was observed in severe and critical patients, consisting of a highly impaired interferon (IFN) type I response (characterized by no IFN-β and low IFN-α production and activity), which was associated with a persistent blood viral load and an exacerbated inflammatory response. …”
Publicado 2020
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2209por Rauch, Daniel A., Olson, Sydney L., Harding, John C., Sundaramoorthi, Hemalatha, Kim, Youngsoo, Zhou, Tianyuan, MacLeod, A. Robert, Challen, Grant, Ratner, Lee“…Recurrent somatic mutations in host genes have exposed the T-cell receptor pathway through nuclear factor κB to interferon regulatory factor 4 (IRF4) as an essential driver for this malignancy. …”
Publicado 2020
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2210“…In this report, we present a 44 years old man who was diagnosed as autoimmune hepatitis (AIH) following the treatment of HBV+HDV hepatitis with pegylated interferon (PegIFN). He presented with complaint of fatigue. …”
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2211“…PURPOSE: We aimed to analyze and evaluate the safety signals of ribavirin-interferon combination through data mining of the US Food and Drug Administration Adverse Event Reporting System (FAERS), so as to provide reference for the rationale use of these agents in the management of relevant toxicities emerging in patients with novel coronavirus pneumonia (COVID-19). …”
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2212por Peters, Sunday O., Hussain, Tanveer, Adenaike, Adeyemi S., Hazzard, Jordan, Morenikeji, Olanrewaju B., De Donato, Marcos, Paul, Sujay, Babar, Masroor, Yakubu, Abdulmojeed, Imumorin, Ikhide G.“…Type 1 interferons plays a major role in the CD8 T-cell response to viral infection. …”
Publicado 2020
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2213por Bharti, Reena, Srivastava, Ashish, Roy, Trisha, Verma, Khushboo, Reddy, D.V. Siva, Shafi, Hasham, Verma, Sonia, Raman, Sunil K., Singh, Amit K., Singh, Jyotsna, Ray, Lipika, Misra, Amit“…Nebulized gamma interferon (IFN-γ) protein has been studied for clinical safety and efficacy against pulmonary tuberculosis (TB). …”
Publicado 2020
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2214“…BACKGROUND: Neutralizing anti-drug antibodies (NAbs) to interferon beta (IFNβ) develop in up to 47% of multiple sclerosis (MS) treated patients inhibiting treatment effect of IFNβ. …”
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2215Koalas vaccinated against Koala retrovirus respond by producing increased levels of interferon-gamma“…The results showed that prior to vaccination, IL-8 was expressed at the highest levels, with at least 200-fold greater expression compared to other cytokines, while CD8 mRNA expression was significantly higher than CD4 mRNA expression level. Interferon-γ was up-regulated at both 4- and 8-weeks post-vaccination while IL-8 was down-regulated at 8-weeks post-vaccination.…”
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2216por Sumida, Tomokazu S., Dulberg, Shai, Schupp, Jonas, Stillwell, Helen A., Axisa, Pierre-Paul, Comi, Michela, Lincoln, Matthew, Unterman, Avraham, Kaminski, Naftali, Madi, Asaf, Kuchroo, Vijay K., Hafler, David A.“…While inhibition of T cell co-inhibitory receptors has revolutionized cancer therapy, the mechanisms governing their expression on human T cells have not been elucidated. Type 1 interferon (IFN-I) modulates T cell immunity in viral infection, autoimmunity, and cancer, and may facilitate induction of T cell exhaustion in chronic viral infection(1,2). …”
Publicado 2020
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2217“…Many parasite infections, including infections of protozoa and helminths, can inhibit inflammatory responses and impact disease outcomes caused by viral, bacterial, or other parasitic infections. Type I interferon (IFN-I) has been recognized as an essential immune effector in the host defense against various pathogens. …”
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2218“…OBJECTIVES: Anti-type I interferon (IFN) autoantibodies have been reported in patients with systemic lupus erythematosus (SLE). …”
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2219por Yuemaier, Munire, Zhou, Zhiqiang, Zhou, Youxu, Wu, Chengwen, Li, Fei, Liang, Xiaodan, Kang, Haihan, Shen, Dongfang, Gao, Fei, Lin, Jinxi“…BACKGROUND: Colon adenocarcinoma (COAD) is one of the most common malignant tumors and has high incidence and mortality rates. The interferon regulatory factor (IRF) family is known as a key transcription factor in the IFN signaling pathway and cellular immunity. …”
Publicado 2020
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2220por Gödecke, Natascha, Riedel, Jan, Herrmann, Sabrina, Behme, Sara, Rand, Ulfert, Kubsch, Tobias, Cicin-Sain, Luka, Hauser, Hansjörg, Köster, Mario, Wirth, Dagmar“…Mammalian first line of defense against viruses is accomplished by the interferon (IFN) system. Viruses have evolved numerous mechanisms to reduce the IFN action allowing them to invade the host and/or to establish latency. …”
Publicado 2020
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