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  1. 2281
    “…Interferon (IFN) induction of IFN‐stimulated genes (ISGs) creates a formidable protective antiviral state. …”
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    BRD9 is a druggable component of interferon‐stimulated gene expression and antiviral activity
  2. 2282
    “…Growing evidence supports the inflammation-driven calcification model, mediated by cytokines such as interferons (IFNs) and tumor necrosis factor (TNF)-α. …”
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    Interferons Are Pro-Inflammatory Cytokines in Sheared-Stressed Human Aortic Valve Endothelial Cells
  3. 2283
    “…Complement-opsonized HIV-1 triggers efficient antiviral type I interferon (IFN) responses in dendritic cells (DCs), which play an important role in protective responses at the earliest stages in retroviral infection. …”
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    Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses
  4. 2284
    “…Defects in the interleukin-12/interferon-gamma (IFN-γ) pathway and anti-IFN-γ antibodies have been associated with severe nontuberculous mycobacteria (NTM) infections. …”
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    Disseminated Mycobacterium avium complex infection in a woman with anti-interferon-γ autoantibodies
  5. 2285
    por Wilkinson, Tom
    Publicado 2021
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    Subcutaneous interferon beta-1a in COVID-19: raking the ashes of an intervention trial
  6. 2286
    “…BACKGROUND: Interferon gamma release assays (IGRAs) are used to detect latent Mycobacterium tuberculosis (M.tb) infection (LTBI) in adults, but their performance in older people is not well-established. …”
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    Interferon gamma release assays for detection of latent Mycobacterium tuberculosis in older Hispanic people
  7. 2287
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    Corrigendum: Type I Interferon Regulates the Survival and Functionality of B Cells in Rainbow Trout
  8. 2288
    “…PURPOSE: To investigate the effects of topical and perilesional interferon alpha-2b as primary treatment for ocular surface squamous neoplasia (OSSN). …”
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    Recombinant Interferon Alpha-2b as Primary Treatment for Ocular Surface Squamous Neoplasia
  9. 2289
    “…SIMPLE SUMMARY: Interferon signaling is mostly studied in the context of immune cells. …”
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    Intrinsic Interferon Signaling Regulates the Cell Death and Mesenchymal Phenotype of Glioblastoma Stem Cells
  10. 2290
    “…Rnaset2(−/−) mice demonstrate upregulation of interferon-stimulated genes and concurrent IFNAR1-dependent neuroinflammation, with infiltration of CD8(+) effector memory T cells and inflammatory monocytes into the grey and white matter. …”
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    Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy
  11. 2291
    por van der Wijst, Monique G. P., Vazquez, Sara E., Hartoularos, George C., Bastard, Paul, Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Mann, Sabrina A., Lynch, Kara L., Yun, Cassandra, Havlir, Diane V., Chamie, Gabriel, Marquez, Carina, Greenhouse, Bryan, Lionakis, Michail S., Norris, Philip J., Dumont, Larry J., Kelly, Kathleen, Zhang, Peng, Zhang, Qian, Gervais, Adrian, Le Voyer, Tom, Whatley, Alexander, Si, Yichen, Byrne, Ashley, Combes, Alexis J., Rao, Arjun Arkal, Song, Yun S., Fragiadakis, Gabriela K., Kangelaris, Kirsten, Calfee, Carolyn S., Erle, David J., Hendrickson, Carolyn, Krummel, Matthew F., Woodruff, Prescott G., Langelier, Charles R., Casanova, Jean-Laurent, Derisi, Joseph L., Anderson, Mark S., Ye, Chun Jimmie
    Publicado 2021
    “…Neutralizing autoantibodies against type I interferons (IFNs) have been found in some patients with critical coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …”
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    Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
  12. 2292
    “…Type 1 interferons, especially interferon-beta, has been reported to be effective in COVID-19 patients in multiple randomized controlled trials. …”
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    Efficacy of subcutaneous interferon-beta in COVID-19: a meta-analysis and systematic review
  13. 2293
    “…Nous avons identifié que des défauts génétiques de l’immunité lié aux interférons de type 1, TLR3 et IRF7-dépendants, peuvent être la cause de formes sévères de pneumopathie à COVID-19. …”
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    Auto-anticorps anti-interférons de type I et COVID-19 sévère
  14. 2294
    “…Recently, non-tuberculosis Mycobacterium-related bone infections among patients with anti-interferon-gamma autoantibody-induced adult-onset immunodeficiency has raised concerns in Southeast Asia, with the common presentations including osteomyelitis. …”
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    Pathological humerus fracture due to anti-interferon-gamma autoantibodies: A case report
  15. 2295
    “…BACKGROUND: In recent years, numerous studies have reported the development or exacerbation of sarcoidosis due to interferon therapy. However, ocular lesions rarely present as initial symptoms. …”
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    Interferon-induced sarcoidosis with uveitis as the initial symptom: a case report and review of the literature
  16. 2296
    “…Interferon lambdas (IFNλ) (also known as type III IFNs) are critical cytokines that combat infection predominantly at barrier tissues, such as the lung, liver, and gastrointestinal tract. …”
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    Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins
  17. 2297
    “…Binding levels and neutralization activity of anti–type 1 interferon autoantibodies peaked during acute coronavirus disease 2019 and markedly decreased thereafter. …”
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    Temporal Dynamics of Anti–Type 1 Interferon Autoantibodies in Patients With Coronavirus Disease 2019
  18. 2298
    “…OBJECTIVE: Adenosine deaminase acting on RNA-1 (ADAR1) enzyme is a type I interferon (IFN)-stimulated gene (ISG) catalyzing the deamination of adenosine-to-inosine, a process called A-to-I RNA editing. …”
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    Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis
  19. 2299
    “…Adult-onset immunodeficiency syndrome due to anti-interferon (IFN)-γ autoantibodies has attracted much attention in recent years. …”
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    Anti-Interferon Autoantibodies in Adult-Onset Immunodeficiency Syndrome and Severe COVID-19 Infection
  20. 2300
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    Sick sinus syndrome associated with Erdheim-Chester disease was reversed by interferon-alpha treatment
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