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  1. 2301
    “…BACKGROUND: Pancreatic cancer (PC) is a highly lethal disease and an increasing cause of cancer-associated mortality worldwide. Interferon regulatory factors (IRFs) play vital roles in immune response and tumor cellular biological processes. …”
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    Comprehensive analysis of expression profile and prognostic significance of interferon regulatory factors in pancreatic cancer
  2. 2302
    “…Recent studies have identified an association between perturbed type I interferon (IFN) responses and the severity of coronavirus disease 2019 (COVID-19). …”
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    Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review
  3. 2303
    “…Our data suggest that astrocytes can resist ZIKV both in an interferon type I- and III-independent manner and suggest that an early and more diverse antiviral response may be more effective in controlling Zika infection. …”
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    Astrocyte Control of Zika Infection Is Independent of Interferon Type I and Type III Expression
  4. 2304
    “…BACKGROUND:  Interferon α-2b is a vital biotherapeutic produced through the recombinant DNA technology in E. coli. …”
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    A Simplified Process for Purification and Refolding of Recombinant Human Interferon-α2b
  5. 2305
    por Kim, Na-Eun, Song, Yoon-Jae
    Publicado 2022
    “…Type I and III interferons (IFNs) and the nucleotide-binding domain (NBD) leucine-rich repeat (LRR)-containing receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome play pivotal roles in the pathogenesis of SARS-CoV-2. …”
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    Coordinated regulation of interferon and inflammasome signaling pathways by SARS-CoV-2 proteins
  6. 2306
    “…The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). …”
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    In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype
  7. 2307
    “…Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote alloimmunization in mice, we hypothesized that IFNα/β may contribute to the increased frequency of alloimmunization in patients with SCD. …”
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    Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease
  8. 2308
    “…Human phospholipid scramblase 1 (PLSCR1) is strongly expressed in response to interferon (IFN) treatment and viral infection, and it has been suggested to play an important role in IFN-dependent antiviral responses. …”
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    The Interferon-Inducible Human PLSCR1 Protein Is a Restriction Factor of Human Cytomegalovirus
  9. 2309
    “…BACKGROUND: The interferon (IFN)-γ release assay (IGRA) has recently been established as a method to evaluate the infection status of tuberculosis instead of the tuberculin skin test. …”
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    In-hospital blood collection increases the rate of indeterminate results in interferon-gamma release assays
  10. 2310
    “…Macrophages are critical components of atherosclerotic lesions and their pro- and anti-inflammatory responses influence atherogenesis. Type-I interferons (IFNs) are cytokines that play an essential role in antiviral responses and inflammatory activation and have been shown to promote atherosclerosis. …”
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    Monocyte and Macrophage Lipid Accumulation Results in Down-Regulated Type-I Interferon Responses
  11. 2311
    “…Standard treatment of hepatitis delta virus (HDV) infection remains pegylated‐interferon alfa (peg‐IFNα) in most centers, which is not only associated with rather low efficacy but several adverse events. …”
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    HBcrAg Levels Are Associated With Virological Response to Treatment With Interferon in Patients With Hepatitis Delta
  12. 2312
    “…We demonstrate that SAgs contribute to S. aureus bacteremia by massively increasing bacterial burden in the liver, and this was mediated by CD4(+) T cells that produced interferon gamma (IFN-γ) to high levels in a SAg-dependent manner. …”
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    Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
  13. 2313
    “…Innate immune response, especially type 1 interferon (IFN) response is considered to play a substantial role in the outcome of SARS-CoV-2 infection. …”
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    Low Serum Levels of Interferon Alpha in COVID-19 Patients Are Associated with Older Age
  14. 2314
    “…Here, we show that, although modulating FEZ1 expression also impacts infection by large DNA viruses in human microglia, macrophages, and fibroblasts, this broad antiviral phenotype is associated with the pre-induction of interferon-stimulated genes (ISGs) in a STING-independent manner. …”
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    FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression
  15. 2315
    “…Damage- or stress-mediated activation of nucleic acid-sensing pathways triggers type I interferon (IFN-I) responses that activate innate immune cells and natural killer cells, promote maturation of dendritic cells, and stimulate adaptive immunity. …”
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    Modulation of Type I Interferon Responses to Influence Tumor-Immune Cross Talk in PDAC
  16. 2316
    “…Dysregulation of type I interferons (IFNs) has been implicated in the pathogenesis of systemic lupus erythematosus (SLE) since the late 1970s. …”
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    Type I Interferons in Systemic Lupus Erythematosus: A Journey from Bench to Bedside
  17. 2317
    “…Here we show that type 1 interferon (IFN-I) regulates co-inhibitory receptor expression on human T cells, inducing PD-1/TIM-3/LAG-3 while inhibiting TIGIT expression. …”
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    Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells
  18. 2318
    “…TF viruses are more resistant to interferon-alpha (IFN-α)-mediated antiviral effects than CC virus, however, its virological relevance in infected individuals remains unclear. …”
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    Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection
  19. 2319
    “…Interferon-beta-1a (IFN-β-1a) can diminish the symptoms of relapsing-remitting multiple sclerosis. …”
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    Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
  20. 2320
    “…While the role of type I interferons (IFNs) in early control of viral replication is clear, less is known about how IFNs can regulate the development of immunopathology and affect disease outcomes. …”
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    Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection
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