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2321por Qu, Shuang, Jiao, Zichen, Lu, Geng, Xu, Jiahan, Yao, Bing, Wang, Ting, Wang, Jun, Yao, Yongzhong, Yan, Xin, Wang, Tao, Liang, Hongwei, Zen, Ke“…Here, we report that human lung adenocarcinoma CD47 is upregulated by interferon-γ (IFN-γ), the level in the tumor microenvironment of which is markedly increased after tumor metastasis and chemotherapy. …”
Publicado 2022
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2322por Serrero, Manutea C, Girault, Virginie, Weigang, Sebastian, Greco, Todd M, Ramos-Nascimento, Ana, Anderson, Fenja, Piras, Antonio, Hickford Martinez, Ana, Hertzog, Jonny, Binz, Anne, Pohlmann, Anja, Prank, Ute, Rehwinkel, Jan, Bauerfeind, Rudolf, Cristea, Ileana M, Pichlmair, Andreas, Kochs, Georg, Sodeik, Beate“…Using cell-free assays and quantitative mass spectrometry, we determined the interactome of capsid-host protein complexes of herpes simplex virus and identified the large dynamin-like GTPase myxovirus resistance protein B (MxB) as an interferon-inducible protein interacting with capsids. …”
Publicado 2022
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2323por Dhayal, Shalinee, Leslie, Kaiyven Afi, Baity, Mohammad, Akhbari, Pouria, Richardson, Sarah J, Russell, Mark A, Morgan, Noel G“…During the development of type 1 diabetes, interferons (IFN) are elaborated from islet-infiltrating immune cells and/or from virally infected β-cells. …”
Publicado 2022
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2324por Ferreira, Margarida L., Vieira, Nicole S. M., Oliveira, Ana L. S., Araújo, João M. M., Pereiro, Ana B.“…Interferon-alpha 2b (IFN-α 2b) is a therapeutic protein used for the treatment of cancer, viral infections, and auto-immune diseases. …”
Publicado 2022
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2325por Tang, Jingyu, Tang, Aoxing, Du, Hanyu, Jia, Nannan, Zhu, Jie, Li, Chuanfeng, Meng, Chunchun, Liu, Guangqing“…PPRV proliferated in caprine endometrial epithelial cells (EECs), caprine skin fibroblasts cells (GSFs), and goat fibroblast cells (GFs), and all cells expressed interferon (IFN) by poly (I: C) stimulation. PPRV infection stimulated expression of type I and type III IFN on EECs, and expression of the latter was significantly stronger, but IFN was not stimulated in fibroblasts (GSFs and GFs). …”
Publicado 2022
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2326“…Interferon plays an important role in immune response of ovarian cancer. …”
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2327“…Here, we developed a neonatal mouse model of enterovirus infection by the enteral route using echovirus 5 and used this model to define the differential roles of type I and III interferons (IFNs) in enterovirus replication in the intestinal epithelium and subsequent dissemination to secondary tissues. …”
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2328“…As a critical component of the host antiviral innate immune response, type I interferon production and signaling play a very important role, especially in the initial phase of the antiviral responses. …”
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2329por Chen, Zhao-Ming, Yang, Xiao-Yun, Li, Zheng-Tu, Guan, Wei-Jie, Qiu, Ye, Li, Shao-Qiang, Zhan, Yang-Qing, Lei, Zi-Ying, Liu, Jing, Zhang, Jian-Quan, Wang, Zhong-Fang, Ye, FengEnlace del recurso
Publicado 2022
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2331por Sari, Gulce, Mulders, Claudia E., Zhu, Jingting, van Oord, Gertine W., Feng, Zongdi, Kreeft‐Voermans, Jolanda J.C., Boonstra, Andre, Vanwolleghem, Thomas“…We previously established liver‐humanized mice as a model for chronic HEV infections, which can be cleared by a 2‐week pegylated (peg)‐Interferon(IFN)α treatment course. However, severe side effects may hamper the use of IFNα in immunocompromised transplant recipient patients. …”
Publicado 2021
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2332por Chuang, Huai‐Chia, Chen, Ming‐Han, Chen, Yi‐Ming, Ciou, Yi‐Ru, Hsueh, Chia‐Hsin, Tsai, Ching‐Yi, Tan, Tse‐Hua“…T cell–specific ECP–transgenic mice (n = 5 per group) displayed early induction of serum interferon‐γ (IFNγ) levels (P = 0.062) and inflammation of multiple tissue types. …”
Publicado 2021
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2333por Hu, Song‐Qun, Xu, Hui‐Min, Qian, Fu‐Ping, Chen, Chang‐Sheng, Wang, Xin, Liu, Dong, Cheng, Lei“…Interferon regulatory factor‐7 (IRF7) is an essential regulator of both innate and adaptive immunity. …”
Publicado 2021
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2334por Simpson-Yap, Steve, Pirmani, Ashkan, De Brouwer, Edward, Peeters, Liesbet M., Geys, Lotte, Parciak, Tina, Helme, Anne, Hillert, Jan, Moreau, Yves, Edan, Gilles, Spelman, Tim, Sharmin, Sifat, McBurney, Robert, Schmidt, Hollie, Bergmann, Arnfin, Braune, Stefan, Stahmann, Alexander, Middleton, Rodden, Salter, Amber, Bebo, Bruce, van der Walt, Anneke, Butzkueven, Helmut, Ozakbas, Serkan, Karabudak, Rana, Boz, Cavit, Alroughani, Raed, Rojas, Juan I, van der Mei, Ingrid, Sciascia do Olival, Guilherme, Magyari, Melinda, Alonso, Ricardo, Nicholas, Richard, Chertcoff, Anibal, Zabalza, Ana, Arrambide, Georgina, Nag, Nupur, Descamps, Annabel, Costers, Lars, Dobson, Ruth, Miller, Aleisha, Rodrigues, Paulo, Prčkovska, Vesna, Comi, Giancarlo, Kalincik, Tomas“…BACKGROUND: Interferon-β, a disease-modifying therapy (DMT) for MS, may be associated with less severe COVID-19 in people with MS. …”
Publicado 2022
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2335por Bojkova, Denisa, Stack, Richard, Rothenburger, Tamara, Kandler, Joshua D., Ciesek, Sandra, Wass, Mark N., Michaelis, Martin, Cinatl, JindrichEnlace del recurso
Publicado 2022
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2336por Maulani, Chaerita, Auerkari, Elza Ibrahim, Masulili, Sri Lelyati C., Kusdhany, Lindawati S., Soeroso, Yuniarti, Soedarsono, Nurtami“…Objectives Interferon-gamma (IFNg) is an immune-regulatory cytokine with a role in host responses to periodontitis. …”
Publicado 2021
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2337“…Owing to the advantage of ultrasound in tissue penetration, an acoustic remote control of bacterial gene expression can be realized by designing a temperature-actuated genetic switch. Cytokine interferon-γ (IFN-γ), an important immune regulatory molecule that plays a significant role in tumor immunotherapy, is used to test the system. …”
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2338“…Although initially little was understood about this virus, recent research has significantly advanced and landed interferons (IFNs) in the spotlight. While Type I and III IFN have long been known as central to antiviral immunity, in the case of COVID‐19 their role was initially controversial. …”
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2339por Shen, Mengjia, Duan, Congcong, Xie, Changhao, Wang, Hongtao, Li, Zhijun, Li, Baiqing, Wang, TaoEnlace del recurso
Publicado 2022
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2340por Cooles, Faye A H, Tarn, Jessica, Lendrem, Dennis W, Naamane, Najib, Lin, Chung MA, Millar, Ben, Maney, Nicola J, Anderson, Amy E, Thalayasingam, Nishanthi, Diboll, Julie, Bondet, Vincent, Duffy, Darragh, Barnes, Michael R, Smith, Graham R, Ng, Sandra, Watson, David, Henkin, Rafael, Cope, Andrew P, Reynard, Louise N, Pratt, Arthur G, Isaacs, John D“…OBJECTIVES: An interferon (IFN) gene signature (IGS) is present in approximately 50% of early, treatment naive rheumatoid arthritis (eRA) patients where it has been shown to negatively impact initial response to treatment. …”
Publicado 2022
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