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221por Kumaki, Yohichi, Day, Craig W., Wandersee, Miles K., Madsen, Jason R., Woolcott, John D., Hoopes, Justin D., Bailey, Kevin W., Wong, Min-Hui, Smee, Donald F., Morrey, John D., Barnard, Dale L.Enlace del recurso
Publicado 2009
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222por Men, Yanjuan, Wang, Yonghui, Wang, Hui, Zhang, Maoyin, Liu, Jing, Chen, Yang, Han, Xufeng, Chen, Renjin, Chen, Quangang, Hu, Ankang“…The host innate immune response to viral infection often involves the activation of type I interferons. Not surprisingly, many viruses have evolved various mechanisms to disable the interferon pathway and evade the antiviral response involving innate immunity. …”
Publicado 2022
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223Enterovirus D68 VP3 Targets the Interferon Regulatory Factor 7 To Inhibit Type I Interferon Responsepor Kang, Jun, Huang, Mengqian, Li, Jinyu, Zhang, Keke, Zhu, Cheng, Liu, Sihua, Zhou, Zhenwei, Wang, Tao, Wang, Zhiyun“…The protease from EV-D68 could impair type I interferon (IFN-I) production. However, the role of the EV-D68 structural protein in antagonizing host antiviral responses remains largely unknown. …”
Publicado 2023
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224por Günther, Claudia, Wolf, Christine, Fennen, Louisa, Rösing, Sarah, Beissert, Stefan, Aringer, Martin, Lee-Kirsch, Min Ae“…Cutaneous lupus erythematosus (CLE), the main manifestation of systemic lupus erythematosus (SLE), is driven by type I interferons (IFNs) and often only partially responds to conventional therapies. …”
Publicado 2023
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225Publicado 1985“…Because antigenic typing of the antiviral activity of these LK and MK preparations revealed that LK contained mainly gamma interferon (IFN- gamma), and MK, primarily IFN-beta, we investigated if any of the fibroblast-inhibiting activities could be attributed to human IFN. …”
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227por Miknis, Zachary J., Magracheva, Eugenia, Li, Wei, Zdanov, Alexander, Kotenko, Sergei V., Wlodawer, Alexander“…Interferon (IFN)-λ1 [also known as interleukin (IL)-29] belongs to the recently discovered group of type III IFNs. …”
Publicado 2010
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228“…BACKGROUND: A functional interferon regulatory element (IRE) has been found in the EnhI/X promoter region of hepatitis B virus (HBV) genome. …”
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229por Yang, Wei, Tan, Juan, Liu, Ruikang, Cui, Xiaoxu, Ma, Qinglin, Geng, Yunqi, Qiao, Wentao“…BACKGROUND: Interferon-induced 35-kDa protein (IFP35) plays important roles in antiviral defense and the progression of some skin cancer diseases. …”
Publicado 2012
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230“…Interferon (IFN)-gamma is an important component of the immune response to viral infections that can have a role both in controlling virus replication and inducing inflammatory damage. …”
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231por Abbas, Zaigham, Tayyab, Ghiasun Nabi, Qureshi, Mustafa, Memon, Mohammad Sadik, Subhan, Amna, Shakir, Tanzila, Jafri, Wasim, Hamid, Saeed“…BACKGROUND: Not enough data are available about the effectiveness of consensus interferon (CIFN) among HCV genotype 3 patients who failed to respond to pegylated interferon and ribavirin. …”
Publicado 2013
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232por Booy, Stephanie, van Eijck, Casper H J, Dogan, Fadime, van Koetsveld, Peter M, Hofland, Leo J“…Pancreatic cancer is a highly aggressive malignancy with limited treatment options. Type-I interferons (e.g. IFN-α/-β) have several anti-tumour activities. …”
Publicado 2014
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233por Motawi, Tarek Kamal, Shaker, Olfat Gamil, El-Maraghy, Shohda Assem, Senousy, Mahmoud Ahmed“…MicroRNAs are messengers during interferon-virus interplay and are involved in antiviral immunity, however, little is known about interferon-related microRNAs regarding their detection in serum and their potential use as non-invasive diagnostic and prognostic biomarkers in chronic hepatitis C (CHC). …”
Publicado 2015
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234por Perot, Brieuc P., Boussier, Jeremy, Yatim, Nader, Rossman, Jeremy S., Ingersoll, Molly A., Albert, Matthew L.“…Notably, the induction of interferon-stimulated genes (ISGs) by IAV was diminished when cells were autophagy competent. …”
Publicado 2018
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235por Weiss, Christopher M., Trobaugh, Derek W., Sun, Chengqun, Lucas, Tiffany M., Diamond, Michael S., Ryman, Kate D., Klimstra, William B.“…Type I interferon (IFN)-stimulated genes (ISGs) have critical roles in inhibiting virus replication and dissemination. …”
Publicado 2018
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236por Yu, Jung-Sheng, Tseng, Chin-Kai, Lin, Chun-Kuang, Hsu, Yao-Chin, Wu, Yu-Hsuan, Hsieh, Ching-Liang, Lee, Jin-Ching“…This antiviral effect of celastrol was associated with celastrol-induced interferon-α (IFN-α) expression and was attenuated by a specific inhibitor of the JAK–STAT signaling pathway downstream of IFN-α or specific shRNA. …”
Publicado 2017
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237por Hellwig, Kerstin, Geissbuehler, Yvonne, Sabidó, Meritxell, Popescu, Catrinel, Adamo, Alessandra, Klinger, Joachim, Ornoy, Asher, Huppke, Peter“…Currently, limited data are available on pregnancy outcomes in patients exposed to interferon-beta (IFN-beta) before or during pregnancy. …”
Publicado 2020
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238por Dowran, Razieh, Nabavi, Seyed Fazel, Habtemariam, Solomon, Banach, Maciej, Shahmohamadnejad, Shiva, Cismaru, Cosmin Andrei, Berindan-Neagoe, Ioana, Sahebnasagh, Adeleh, Nabavi, Seyed Mohammad“…Various interferon (IFN)-inducible transmembrane (IFITM) proteins are known to be expressed in human tissues though only IFITM 1–3 are inducible by IFN. …”
Publicado 2020
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239por Hasselbalch, H.C., Skov, V., Kjær, L., Ellervik, C., Poulsen, A., Poulsen, T.D., Nielsen, C.H.“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits an interferon (IFN) deficiency state, which aggravates the type I interferon deficiency and slow IFN responses, which associate with e.g. aging and obesity. …”
Publicado 2021
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240por Kuriyama, Yuko, Shimizu, Akira, Kanai, Saki, Oikawa, Daisuke, Motegi, Sei-ichiro, Tokunaga, Fuminori, Ishikawa, Osamu“…Type I interferon (IFN) plays a crucial role in innate and adaptive immunity, and aberrant IFN responses are involved in systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) and dermatomyositis (DM). …”
Publicado 2021
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