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241por Lai, Yalan, Xia, Xiaoyan, Cheng, Anchun, Wang, Mingshu, Ou, Xumin, Mao, Sai, Sun, Di, Zhang, Shaqiu, Yang, Qiao, Wu, Ying, Zhu, Dekang, Jia, Renyong, Chen, Shun, Liu, Mafeng, Zhao, Xin-Xin, Huang, Juan, Gao, Qun, Tian, Bin, Liu, Yunya, Yu, Yanling, Zhang, Ling, Pan, Leichang“…The results indicate that the DHAV-1 3C protein inhibits the pathway upstream of interferon (IFN)-β by targeting the interferon regulatory factor 7 (IRF7) protein. …”
Publicado 2021
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242“…The phleboviral NSs protein is an established virulence factor, acting as antagonist of the antiviral interferon (IFN) system. Consistently, we previously reported that SFSV NSs targets the induction of IFN mRNA synthesis by specifically binding to the DNA-binding domain of the IFN transcription factor IRF3. …”
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243“…HHV-8 encodes four viral interferon regulatory factors (vIRFs) that are believed to contribute to viral latency (in PEL cells, at least) and/or to productive replication via suppression of cellular antiviral and stress signaling. …”
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244“…Pestiviruses are a class of viruses that in some cases can cause persistent infection of the host, thus posing a threat to the livestock industry. Interferons (IFNs) are a group of secreted proteins that play a crucial role in antiviral defense. …”
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245“…In this issue of EMBO Molecular Medicine, Carvajal Ibanez et al (2023) reveal that IFN‐β, a type‐I interferon, induces cell‐type‐specific interferon‐stimulated genes (ISGs) and regulates global protein synthesis by orchestrating mTOR1 activity and stem cell cycle that retain NSCs at the G(0) phase and repress Sox2 expression. …”
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246“…Interferons are a group of immunomodulatory substances produced by the human immune system in response to the presence of pathogens, especially during viral and bacterial infections. …”
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247por Shajari, Rasoul, Adeli, Seyed Hasan, Bagherzadeh, Mohammad, Asghari, Akram, Tabaraii, Reihane, Alikhani, Aliakbar, Jabbari, Amir, Razavinia, Fateme, Shakeri, Mansoureh, Jafari, Saeede, Ahmadpour, Sajjad, Vafaeimanesh, Jamshid“…In this study, we aimed to study the effect of interferon on the treatment of hypoxemia caused by COVID-19. …”
Publicado 2023
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248“…The interferon pathway is the first line of defense in viral infection in all mammals, and its induction stimulates broad expression of interferon-stimulated genes (ISGs). …”
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249por Pasquesi, Giulia Irene Maria, Allen, Holly, Ivancevic, Atma, Barbachano-Guerrero, Arturo, Joyner, Olivia, Guo, Kejun, Simpson, David M., Gapin, Keala, Horton, Isabella, Nguyen, Lily, Yang, Qing, Warren, Cody J., Florea, Liliana D., Bitler, Benjamin G., Santiago, Mario L., Sawyer, Sara L., Chuong, Edward B.“…Our findings uncover a primate-specific axis controlling interferon signaling and show how a transposon exonization event can be co-opted for immune regulation.…”
Publicado 2023
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250“…In this review, we summarize the stimulator of interferon genes (STING) pathway, its specific role in the pathogenesis of DNA damage and skin cancer, and STING-specific therapies that may fight both melanoma and non-melanoma skin (NMSC) cancers. …”
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251“…Interferons (IFN) are an assemblage of signaling proteins made and released by various host cells in response to stimuli, including viruses. …”
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252“…With this in mind, search of the target genes for interferon (IFN) induction appears of interest. IFNs are multi-functional cytokines. …”
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253Publicado 1987“…The mitogenic effects of ECGF are inhibited by the lymphokine gamma-interferon (gamma-IFN) in a dose- dependent manner. …”
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254“…Leukocytes infected with vaccinia virus produce a substance with the properties of interferon. The evidence presented suggests that leukocytes also produce interferon in vivo and that this interferon is related to the observed protective effect on the outcome of intracerebral vesicular stomatitis virus challenge in mice. …”
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255Publicado 1980“…Evidence is presented that interferon (IF) is a major mediator of the human concanavalin A (Con A) suppressor cell. …”
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256Publicado 1980“…Interferon treatment impairs the ability of cells to redistribute cell surface receptors for concanavalin A (Con A). …”
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257Publicado 1982“…The effect of human interferon alpha on the differentiation of functional populations of lymphocytes during the human allogeneic response in vitro was studied. …”
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259por Youngner, Julius S.Materias: “…Interferon Induction ⋅ I…”
Publicado 1970
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