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29281por Klim, S. M., Amerstorfer, F., Glehr, G., Hauer, G., Smolle, M. A., Leitner, L., Leithner, A., Glehr, M.“…The serum leukocyte count, C-reactive protein (CRP), interleukin-6, procalcitonin, interferon alpha, and fibrinogen were assessed 1 day prior to surgery. …”
Publicado 2020
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29282por Naughton, Michelle, Moffat, Jill, Eleftheriadis, George, de la Vega Gallardo, Nira, Young, Andrew, Falconer, John, Hawkins, Kristen, Pearson, Ben, Perbal, Bernard, Hogan, Andrew, Moynagh, Paul, Loveless, Sam, Robertson, Neil P., Gran, Bruno, Kee, Rachael, Hughes, Stella, McDonnell, Gavin, Howell, Owain, Fitzgerald, Denise C.“…RESULTS: Plasma CCN3 levels were comparable between collective MS cohorts and controls but were significantly higher in progressive versus relapsing-remitting MS and between patients on interferon-β versus natalizumab. Higher body mass index was associated with higher CCN3 levels in controls as reported previously, but this correlation was absent in MS patients. …”
Publicado 2020
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29283“…MATERIAL AND METHODS: We pretreated cells and mice with luteolin before infection with RSV, the virus titer, expressions of RSV-F, interferon (IFN)-stimulated genes (ISGs), and production of IFN-α and IFN-β were determined by plaque assay, RT-qPCR, and ELISA, respectively. …”
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29284por Qie, Shuyan, Ran, Yuanyuan, Lu, Xiaosheng, Su, Wei, Li, Wei, Xi, Jianing, Gong, Weijun, Liu, Zongjian“…In this study, the resting microglia were stimulated to M1 microglia with lipopolysaccharide (LPS) and interferon-γ (IFN-γ), and then treated with vehicle or candesartan for 24 h. …”
Publicado 2020
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29285“…We measured levels of total lymphocytes, CD3(+) T cells, CD4(+) T cells, CD8(+) T cells, CD19(+) B cells, and CD56(+) NK cells and the serum concentrations of interleukin- (IL-) 1, IL-4, IL-6, IL-8, IL-10, transforming growth factor beta (TGF-β), tumor necrosis factor alpha (TNF-α), and interferon gamma (IFN-γ) by flow cytometry. We found that in most postrecovery patients, levels of total lymphocytes (66.67%), CD3(+) T cells (54.55%), CD4(+) T cells (54.55%), CD8(+) T cells (81.82%), CD19(+) B cells (69.70%), and CD56(+) NK cells (51.52%) remained lower than normal, whereas most patients showed normal levels of IL-2 (100%), IL-4 (80.88%), IL-6 (79.41%), IL-10 (98.53%), TNF-α (89.71%), IFN-γ (100%), and IL-17 (97.06%). …”
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29286por Fleming, Damarius S., Miller, Laura C., Tian, Yun, Li, Yonghai, Ma, Wenjun, Sang, Yongming“…Interferon (IFN) cytokines induce an autonomous antiviral state in cells of the infected site to restrict virus spreading and critically regulate overall antiviral response. …”
Publicado 2020
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29287por Hachim, Mahmood Yaseen, Hachim, Ibrahim Yaseen, Talaat, Iman M., Yakout, Nada M., Hamoudi, Rifat“…Moreover, the M1 high basal-like breast cancer group showed a higher expression of interferon-gamma induced chemokines and guanylate-binding proteins (GBPs) involved in immunity against microbes. …”
Publicado 2020
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29288“…Similarly, expression of cecal inflammatory cytokines (IL-10, IL-1β, and interferon-γ) was not affected by MSM, DEP, or their combination. …”
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29289por Frimpong, Augustina, Amponsah, Jones, Adjokatseh, Abigail Sena, Agyemang, Dorothy, Bentum-Ennin, Lutterodt, Ofori, Ebenezer Addo, Kyei-Baafour, Eric, Akyea-Mensah, Kwadwo, Adu, Bright, Mensah, Gloria Ivy, Amoah, Linda Eva, Kusi, Kwadwo Asamoah“…We measured and compared the plasma levels of pro-inflammatory mediators including tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), interleukin (IL)-6, IL-12p70, IL-17A, and granzyme B, the anti-inflammatory cytokine IL-4 and the regulatory cytokine IL-10 from children with asymptomatic malaria infections (either microscopic or submicroscopic) and uninfected controls using Luminex. …”
Publicado 2020
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29290por Dai, Hanren, Tong, Chuan, Shi, Daiwei, Chen, Meixia, Guo, Yelei, Chen, Deyun, Han, Xiao, Wang, Hua, Wang, Yao, Shen, Pingping“…Changes in EPC counts, VEGF, SDF-1, sVEGFR2, and interferon (IFN)-γ after cell infusion were associated with survival. …”
Publicado 2020
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29291por Chan, Godfrey Chi-Fung, Liu, Anthony Pak-Yin, Shing, Matthew Ming-Kong, Ku, Dennis Tak-Noi“…For craniopharyngioma, M:F=15:13 and median age was 7.4yrs (2mons-16.5yrs). 12/28 children had surgery alone and 13/28 had focal RT post-surgery with better outcome. 3 underwent intra-cystic interferon-beta also stable. For ATRT, M:F=7:8 and median age was 2.3yrs (4mos-14.2yrs). 2 had metastatic disease and 7/18 patients remained alive. …”
Publicado 2020
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29292por Gruenewald, Analise L., Garcia-Mesa, Yoelvis, Gill, Alexander J, Garza, Rolando, Gelman, Benjamin B., Kolson, Dennis L.“…Several regions, including posterior cingulate cortex, globus pallidus, and cerebellum, showed a distinct pattern of higher type I interferon (IFN)-stimulated gene and immunoproteasome expression. …”
Publicado 2020
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29293por Wang, Ping-Huai, Lin, Shu-Yung, Lee, Susan Shih-Jung, Lin, Shu-Wen, Lee, Chih-Yuan, Wei, Yu-Feng, Shu, Chin-Chung, Wang, Jann-Yuan, Yu, Chong-Jen“…In conclusion, the QFT-Plus provides more reliable positive consistency than does the QFT-GIT. The CD4 interferon-γ response might play a role in maintaining positivity of LTBI.…”
Publicado 2020
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29294por Mostafa, Ahmed, Blaurock, Claudia, Scheibner, David, Müller, Christin, Blohm, Ulrike, Schäfer, Alexander, Gischke, Marcel, Salaheldin, Ahmed H, Nooh, Hanaa Z, Ali, Mohamed A, Breithaupt, Angele, Mettenleiter, Thomas C, Pleschka, Stephan, Abdelwhab, Elsayed M“…Furthermore, exchange of the PB2, PA, and NS segments of H5N8 by those of H9N2 increased replication, polymerase activity and interferon antagonism of the H5N8 reassortants in human cells. …”
Publicado 2020
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29295por Glaser, Nicole, Chu, Steven, Hung, Benjamin, Fernandez, Luis, Wulff, Heike, Tancredi, Daniel, ODonnell, Martha E“…In brain tissue lysates, concentrations of CCL3, CCL5, interferon (IFN)-γ and MMP-9 were significantly elevated during acute DKA. …”
Publicado 2020
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29296por Liu, Kun, Yang, Tong, Peng, Xue‐Fang, Lv, Shou‐Ming, Ye, Xiao‐lei, Zhao, Tian‐Shuo, Li, Jia‐Chen, Shao, Zhong‐Jun, Lu, Qing‐Bin, Li, Jing‐Yun, Liu, Wei“…In contrast, IL‐5, IL‐1β and Interferon (IFN)‐γ did not show significant inter‐group difference. …”
Publicado 2020
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29297por Marra, Fiona, Smolders, Elise J., El-Sherif, Omar, Boyle, Alison, Davidson, Katherine, Sommerville, Andrew J., Marzolini, Catia, Siccardi, Marco, Burger, David, Gibbons, Sara, Khoo, Saye, Back, David“…FINDINGS: Remdesivir, dexamethasone, azithromycin, favipiravir, lopinavir/ritonavir, atazanavir, hydroxychloroquine, interferon beta, ribavirin, tocilizumab, anakinra and sarilumab were identified as experimental drugs being used in COVID-19 trials as of November 2020. …”
Publicado 2020
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29298“…Further, we evaluated its immunopotentiating function by measuring the relative RNA expression levels of splenic immune-related genes such as interleukin 1β (IL-1β) and interferon-γ (IFN-γ), after intramuscular injection of increasing concentrations of the extracted LPS in specific pathogen-free (SPF) chick. …”
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29299por Ahmed, Firoz“…Finally, in-depth analysis and literature mining revealed that Vitamin D binds with its receptor and could work through two different pathways: (i) it inhibits the expression of pro-inflammatory cytokines through blocking the TNF induced NFkB1 signaling pathway; and (ii) it initiates the expression of interferon-stimulating genes (ISGs) for antiviral defense program through activating the IFN-α induced Jak-STAT signaling pathway. …”
Publicado 2020
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29300por Oshi, Masanori, Tokumaru, Yoshihisa, Patel, Ankit, Yan, Li, Matsuyama, Ryusei, Endo, Itaru, Katz, Matthew H.G., Takabe, Kazuaki“…The high score was also significantly associated with reduced CD8(+) T cell infiltration of tumors, but with high levels of interferon-γ and cytolytic activity in tumors. The four-gene score correlated with the area under the curve of irinotecan and sorafenib in primary pancreatic cancer, and with paclitaxel and doxorubicin in metastatic pancreatic cancer. …”
Publicado 2020
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