-
29301por Chen, Xiaochen, Liu, Xing, Duan, Song, Tang, Renhai, Zhou, Sujuan, Ye, Runhua, Yang, Yuecheng, Wang, Jibao, Yao, Shitang, He, Na“…FIB-4 ≤ 3.25) had higher plasma levels of interleukin (IL)-1β, IL-6, IL-7, IL-9, IL-12, IL-15, IL-17, granulocyte macrophage colony stimulating factor (GM-CSF), Interferon-γ (IFN-γ), tumor necrosis factor (TNF-α), IL-4, IL-10, IL-13, fibroblast growth factor 2 (FGF-basic), and Monocyte chemoattractant protein-1 (MCP-1). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29302por Garg, Saurabh K., Welsh, Eric A., Fang, Bin, Hernandez, Yuliana I., Rose, Trevor, Gray, Jhanelle, Koomen, John M., Berglund, Anders, Mulé, James J., Markowitz, Joseph“…Pathway analyses showed interferon (IFN)-γ-mediated signaling via NF-κB and JAK/STAT pathways to affect immune processes in a cell-specific manner and to interact with the inducible nitric oxide synthase. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29303por Stebbing, Justin, Sánchez Nievas, Ginés, Falcone, Marco, Youhanna, Sonia, Richardson, Peter, Ottaviani, Silvia, Shen, Joanne X., Sommerauer, Christian, Tiseo, Giusy, Ghiadoni, Lorenzo, Virdis, Agostino, Monzani, Fabio, Rizos, Luis Romero, Forfori, Francesco, Avendaño Céspedes, Almudena, De Marco, Salvatore, Carrozzi, Laura, Lena, Fabio, Sánchez-Jurado, Pedro Manuel, Lacerenza, Leonardo Gianluca, Cesira, Nencioni, Caldevilla Bernardo, David, Perrella, Antonio, Niccoli, Laura, Méndez, Lourdes Sáez, Matarrese, Daniela, Goletti, Delia, Tan, Yee-Joo, Monteil, Vanessa, Dranitsaris, George, Cantini, Fabrizio, Farcomeni, Alessio, Dutta, Shuchismita, Burley, Stephen K., Zhang, Haibo, Pistello, Mauro, Li, William, Romero, Marta Mas, Andrés Pretel, Fernando, Simón-Talero, Rafaela Sánchez, García-Molina, Rafael, Kutter, Claudia, Felce, James H., Nizami, Zehra F., Miklosi, Andras G., Penninger, Josef M., Menichetti, Francesco, Mirazimi, Ali, Abizanda, Pedro, Lauschke, Volker M.“…Using organotypic 3D cultures of primary human liver cells, we demonstrate that interferon-α2 increases ACE2 expression and SARS-CoV-2 infectivity in parenchymal cells by greater than fivefold. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29304por Kuca-Warnawin, Ewa, Janicka, Iwona, Szczęsny, Piotr, Olesińska, Marzena, Bonek, Krzysztof, Głuszko, Piotr, Kontny, Ewa“…Untreated and cytokine (tumor necrosis factor α + interferon γ)-treated ASCs were co-cultured with allogenic, mitogen (phytohemagglutinin)-stimulated peripheral blood mononuclear cells (PBMCs) or purified anti-CD3/CD28-activated CD4(+) T lymphocytes. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29305por Sandling, Johanna K, Pucholt, Pascal, Hultin Rosenberg, Lina, Farias, Fabiana H G, Kozyrev, Sergey V, Eloranta, Maija-Leena, Alexsson, Andrei, Bianchi, Matteo, Padyukov, Leonid, Bengtsson, Christine, Jonsson, Roland, Omdal, Roald, Lie, Benedicte A, Massarenti, Laura, Steffensen, Rudi, Jakobsen, Marianne A, Lillevang, Søren T, Lerang, Karoline, Molberg, Øyvind, Voss, Anne, Troldborg, Anne, Jacobsen, Søren, Syvänen, Ann-Christine, Jönsen, Andreas, Gunnarsson, Iva, Svenungsson, Elisabet, Rantapää-Dahlqvist, Solbritt, Bengtsson, Anders A, Sjöwall, Christopher, Leonard, Dag, Lindblad-Toh, Kerstin, Rönnblom, Lars“…RESULTS: We identified two main independent pathways involved in SLE susceptibility: T lymphocyte differentiation and innate immunity, characterised by HLA and interferon, respectively. Pathway PRS defined pathways in individual patients, who on average were positive for seven pathways. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29306por Guo, Qiang, Chen, Ximiao, Chen, Jiaoxiang, Zheng, Gang, Xie, Chenglong, Wu, Hongqiang, Miao, Zhimin, Lin, Yan, Wang, Xiangyang, Gao, Weiyang, Zheng, Xiangtao, Pan, Zongyou, Zhou, Yifei, Wu, Yaosen, Zhang, Xiaolei“…Previous research demonstrated that the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) participates in DNA damage response. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29307por Schoos, Alexandra, Chantziaras, Ilias, Vandenabeele, Jordy, Biebaut, Evelien, Meyer, Evelyne, Cools, An, Devreese, Mathias, Maes, Dominiek“…Performance and health parameters investigated in sows were gestation length, farrowing duration, litter characteristics, colostrum yield and quality (Immunoglobulin G), litter weight gain, weaning-to-estrus interval, pregnancy rate, rectal temperature, acute phase proteins and inflammatory markers serum amyloid A, haptoglobin, interferon γ, interleukin 1β and 6 backfat, constipation and feed refusal. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29308por Saleh, Haidy A., Ramdan, Eman, Elmazar, Mohey M., Azzazy, Hassan M. E., Abdelnaser, Anwar“…Then, we compared the anti-inflammatory effects of curcumin (CUR), resveratrol (RES) and sulforaphane (SFN) against lipopolysaccharide/interferon-gamma (LPS/IFN-γ)-mediated inflammation in the absence or presence of DOX. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29309por Natoli, Marina, Gallon, John, Lu, Haonan, Amgheib, Ala, Pinato, David J, Mauri, Francesco A, Marafioti, Teresa, Akarca, Ayse U, Ullmo, Ines, Ip, Jacey, Aboagye, Eric O, Brown, Robert, Karadimitris, Anastasios, Ghaem-Maghami, Sadaf“…DNA methyltransferase inhibitors (DNMTi)-induced ERV expression triggers interferon responses in ovarian cancer cells via the viral sensing machinery. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29310por Stringhini, Marco, Mock, Jacqueline, Fontana, Vanessa, Murer, Patrizia, Neri, Dario“…Abbreviations: CTLA-4: Cytotoxic T-lymphocytes-associated protein 4; EGFR: Epidermal growth factor receptor; HVEM: Herpesvirus entry mediator; IFNγ: Interferon-gamma; LIGHT: Lymphotoxin, exhibits inducible expression and competes with HSV glycoprotein D for binding to herpesvirus entry mediator, a receptor expressed on T lymphocytes; LTβR: Lymphotoxin beta receptor; NF-κB: Nuclear factor “kappa-light-chain-enhancer” of activated B cells; NK: Natural killer cells; PD-1: Programmed cell death protein 1; PD-L1: Programmed death-ligand 1; TNF: Tumor necrosis factor.…”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29311“…Tuberculin skin test (TST) and interferon gamma release assays (IGRAs) are the main diagnostic tools for LTBI, however, both present strengths and limitations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29312por Ahmetlic, Fatima, Fauser, Josia, Riedel, Tanja, Bauer, Vera, Flessner, Carolin, Hömberg, Nadine, Hennel, Roman, Brenner, Ellen, Lauber, Kirsten, Röcken, Martin, Mocikat, Ralph“…The proinflammatory cytokines interferon-γ (IFN-γ) and tumor necrosis factor (TNF) were necessary for the survival benefit as well as for senescence induction in the λ-MYC model. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29313por Machahua, Carlos, Buendia-Roldan, Ivette, Ocaña-Guzman, Ranferi, Molina-Molina, María, Pardo, Annie, Chavez-Galan, Leslie, Selman, Moises“…Additionally, a significant increase in the levels of interleukin-6 and interferon gamma was observed in isolated CD4+T cells and plasma of ILA subjects. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29314“…BACKGROUND: Interferon regulatory factor 4 (IRF4) is a transcription factor from the IRF factor family that exerts regulatory functions in the immune system and oncogenesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29315por Baatarkhuu, Oidov, Lee, Jae Seung, Amarsanaa, Jazag, Kim, Do Young, Ahn, Sang Hoon, Naranzul, Nyamsuren, Enkhtuya, Damba, Choijamts, Nagir, Batbayar, Purev, Otgonbayar, Radnaa, Saruul, Bat-Ulzii, Gantuul, Chuluunbaatar, Gegeebadrakh, Baljinnyam, Tuvshinbayar, Narangerel, Badamsuren, Dorjgotov, Ulzmaa, Galsan, Otgonbold, Jamiyandorj, Han, Kwang-Hyub“…METHODS: Between 2015 to 2019, 23 (0.5%) and 5,005 patients (99.5%) with genotype 1a and 1b HCV, respectively, were treated with a fixed-dose tablet containing 90 mg ledipasvir and 400 mg sofosbuvir for 12 weeks, and 81 patients (1.6%) with previous experience of interferon (IFN)-based treatment received additional 1,000 mg ribavirin. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29316Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19“…However, as the anti-viral interferon I signaling is also upregulated in DS, this might increase the initial anti-viral response, inhibiting viral genome release, viral replication and viral assembly. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29317“…Clinical and histopathologic features of pernio are well described, but the pathogenesis is not entirely understood; vasospasm and a type I interferon (IFN-I) immune response are likely involved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29318por Riahi, Insaf, Marquis, Virginie, Pérez-Vendrell, Anna Maria, Brufau, Joaquim, Esteve-Garcia, Enric, Ramos, Antonio J.“…The expression of interleukin 6, interleukin 1β and interferon-γ increased in jejunum tissues of broilers fed 5 mg/kg of DON compared with controls. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29319por Pavelek, Zbyšek, Sobíšek, Lukáš, Šarláková, Jana, Potužník, Pavel, Peterka, Marek, Štětkárová, Ivana, Štourač, Pavel, Mareš, Jan, Hradílek, Pavel, Ampapa, Radek, Grünermelová, Markéta, Vachová, Marta, Recmanová, Eva, Angelucci, Francesco, Halúsková, Simona, Vališ, Martin“…Well-established drugs used for MS patients after the first demyelinating event in the Czech Republic include glatiramer acetate (GA), interferon beta-1a (IFNβ-1a), IFN beta-1b (IFNβ-1b), peginterferon beta-1a (peg-IFNβ-1a), and teriflunomide. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29320por Pitsillou, Eleni, Liang, Julia, Ververis, Katherine, Hung, Andrew, Karagiannis, Tom C.“…Further, the PL(pro) possesses deubiquitinating activity affecting key signalling pathways, including inhibition of interferon and innate immune antagonism. Therefore, inhibition of PL(pro) activity with small molecules is an important research direction. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto