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  1. 29321
    “…We also found that cytokines, including interferon-gamma (IFNγ) and tumor necrosis factor-alpha (TNFα) secreted by activated T cells, damaged tumor cells in a cell contact-independent manner. …”
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    Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation
  2. 29322
    “…TB screening prior to IFX was performed with chest X‐ray and/or computed tomography [CT] and immune reactivity testing (interferon‐γ release assay and/or tuberculin skin test). …”
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    Targeted versus universal tuberculosis chemoprophylaxis in 1968 patients with inflammatory bowel disease receiving anti‐TNF therapy in a tuberculosis endemic region
  3. 29323
    “…PURPOSE: MicroRNA-21 (miR-21) influences the Th2 immune pathway by suppressing the expressions of interleukin (IL)-12 and interferon (IFN)-γ. The effects of miR-21 suppression on alveolar macrophage polarization and airway inflammation are not known. …”
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    MicroRNA-21 Inhibition Suppresses Alveolar M2 Macrophages in an Ovalbumin-Induced Allergic Asthma Mice Model
  4. 29324
    “…As IDO is key for maternal immune tolerance and induced in response to interferon tau (IFNT, ruminant maternal recognition of pregnancy factor), we examined the responsiveness to IFNT on peripheral blood mononuclear cells (PBMC) isolated from healthy and repeat breeder cows. …”
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    Metabolomic profiles of plasma and uterine luminal fluids from healthy and repeat breeder Holstein cows
  5. 29325
    “…However, all vaccinated mice developed comparable interferon gamma T cell responses to the VEEV E2 peptide pools. …”
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    A Monovalent and Trivalent MVA-Based Vaccine Completely Protects Mice Against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenge
  6. 29326
    “…Through single cell transcriptomic analyses, we found that the maternal-fetal interface of SARS-CoV-2-infected women exhibited markers associated with pregnancy complications, such as preeclampsia, and robust immune responses, including increased activation of placental NK and T cells and increased expression of interferon-related genes. Overall, this study suggests that SARS-CoV-2 is associated with immune activation at the maternal-fetal interface even in the absence of detectable local viral invasion. …”
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    SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface
  7. 29327
    “…Knockdown of TSPAN5 also influenced the expression of genes associated with interferon signaling pathways. Finally, we determined that TSPAN5 SNPs were associated with acamprosate treatment outcomes in AUD patients. …”
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    TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response
  8. 29328
    “…After discontinuing interferon therapy, he was followed up at his request without anticancer treatment. …”
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    Jejunal limb obstruction by a tumor thrombus from pancreatic metastasis of renal cell carcinoma: a case report
  9. 29329
    “…Lipopolysaccharide (LPS) and interferon gamma (IFN-γ) were used to stimulate human monocytic cell lines (THP-1) and rat alveolar macrophage-derived cell lines (NR8383) to induce M1 phenotype macrophages. …”
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    Macrophage-derived netrin-1 contributes to endometriosis-associated pain
  10. 29330
    “…We also observed a decrease in CD20(+) T-cell numbers (p < 0.0001) and percentages (p < 0.0001), and a clear remodeling of the T-cell compartment characterized by relative increases of the naive/effector ratios in CD4(+) (p = 0.002) and CD8(+) (p = 0.002) T cells and relative decreases of CD4(+) (p = 0.03) and CD8(+) (p = 0.004) T cells producing interferon-gamma. Total monocyte numbers increased (p = 0.002), but no changes were observed in those producing inflammatory cytokines. …”
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    Effect of Ocrelizumab in Blood Leukocytes of Patients With Primary Progressive MS
  11. 29331
    “…A lentivirus was used to overexpress SAMHD1 and stimulator of interferon genes (STING) in A549 cells; and RT-qPCR and western blot analysis were performed to verify their levels. …”
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    SAMHD1 can suppress lung adenocarcinoma progression through the negative regulation of STING
  12. 29332
    “…LTBI status was assessed by interferon gamma release assay. Plasma was used to measure systemic inflammation markers using immunoassays: IFNβ, CRP, AGP, I-FABP, IFNγ, IL-1β, soluble CD14 (sCD14), sCD163, TNF, IL-6, IL-17a and IL-13. …”
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    Systemic Inflammation in Pregnant Women With Latent Tuberculosis Infection
  13. 29333
    “…In addition, therapies based on the use of hydroxychloroquine, chloroquine, remdesvir, ribavirin, interferon or lopinavir-ritonavir were also initially used. …”
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    Medical progress: Stem cells as a new therapeutic strategy for COVID-19
  14. 29334
    “…METHODS: Single-cell analysis, metabolic flux and confocal analysis of NK cells from patients with metastatic breast cancer and healthy controls RESULTS: In addition to reduced interferon-γ production and cytotoxicity, peripheral blood NK cells from patients had clear metabolic deficits including reduced glycolysis and oxidative phosphorylation. …”
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    TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer
  15. 29335
    “…Anti-HIV effect was monitored by a p24 antigen enzyme-linked immunosorbent assay kit. interferon (IFN)-α, IFN-β, or IFN-λ production was quantified using each subtype-specific enzyme-linked immunosorbent assay kit. …”
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    Profiles of MicroRNAs in Interleukin–27-Induced HIV-Resistant T Cells: Identification of a Novel Antiviral MicroRNA
  16. 29336
    “…Routine biochemistry, serum levels of interleukin-6, tumor necrosis factor-α, interferon-γ, 8-isoprostaglandin F2α and nitrates were determined. …”
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    Vitamin D receptor gene ApaI and FokI polymorphisms and its association with inflammation and oxidative stress in vitamin D sufficient Caucasian Spanish children
  17. 29337
    “…Notably, monocytes exhibited bifurcated genomic states, with expression of a cytokine gene module exemplified by CCL4 (MIP-1β) associated with survival and an interferon signaling module associated with death. These gene modules were correlated with higher levels of MIP-1β and CXCL10 levels in plasma, respectively. …”
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    Bifurcated monocyte states are predictive of mortality in severe COVID-19
  18. 29338
    “…Primary outcomes are BCG-specific interferon-γ ELISpot responses 8 weeks after BCG immunisation and for other vaccines, antibody responses to key vaccine antigens at 4 weeks after immunisation. …”
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    Effect of intensive treatment for schistosomiasis on immune responses to vaccines among rural Ugandan island adolescents: randomised controlled trial protocol A for the ‘POPulation differences in VACcine responses’ (POPVAC) programme
  19. 29339
    “…In menstrual blood plasma, C5/C5a, interleukin‐6 (IL‐6), IL‐1β, and CXCL8 were detected in high concentrations, whereas IL‐2, IL‐12p70, XCL1/Lymphotactin, and interferon‐γ were low. The most pronounced median differences between menstrual and peripheral blood plasma were found for IL‐6, IL‐1β, and CXCL8. …”
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    The cytokine profile of menstrual blood
  20. 29340
    “…OBJECTIVE: In phase II and III trials, anifrolumab, a human monoclonal antibody that binds type I interferon receptor subunit 1, has shown efficacy in adults with moderate to severe SLE. …”
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    Safety profile of anifrolumab in patients with active SLE: an integrated analysis of phase II and III trials
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