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  1. 29621
    “…Based on the maximum nontoxic concentration (TC(0)), half-maximal toxic concentration (TC(50)), half-maximal inhibitory concentration (IC(50)), and therapeutic index (TI), interferon-β (IFN-β) and interleukin-6 (IL-6) levels were measured using enzyme-linked immunosorbent assay (ELISA), and the gene expression of TLR7, MyD88, tumor necrosis factor receptor-associated factor 6 (TRAF6), c-Jun amino terminal kinase (JNK), p38 mitogen-activated protein kinase (p38 MAPK), and p65 nuclear transcription factor-kappa B (p65 NF-κB) was quantified using reverse transcription-polymerase chain reaction (RT-PCR). …”
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    Screening of Antiviral Components of Yinhuapinggan Granule and Protective Effects of Yinhuapinggan Granule on MDCK Cells with Influenza A/H1N1 Virus
  2. 29622
    por Mogensen, Trine H.
    Publicado 2022
    “…BACKGROUND: During the past 2 years, studies on patients with SARS-CoV-2 infection have revealed rare inborn errors of immunity (IEIs) in type interferon (IFN) pathways underlying critical COVID-19 pneumonia. …”
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    Human genetics of SARS-CoV-2 infection and critical COVID-19
  3. 29623
    “…In addition, the activity of natural killer (NK) cells decreased significantly, the levels of regulatory T cells (Tregs), interleukin-10 (IL-10) and transforming growth factor-β (TGF-β) increased significantly and the levels of interleukin-2 (IL-2), interleukin-6 (IL-6), interleukin-17 (IL-17), interleukin-23 (IL-23), tumour necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) decreased significantly in the HO-1/BMMSC group compared with the BMMSC group. …”
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    Effect of HO-1-modified BMMSCs on immune function in liver transplantation
  4. 29624
    por Pekayvaz, Kami, Leunig, Alexander, Kaiser, Rainer, Joppich, Markus, Brambs, Sophia, Janjic, Aleksandar, Popp, Oliver, Nixdorf, Daniel, Fumagalli, Valeria, Schmidt, Nora, Polewka, Vivien, Anjum, Afra, Knottenberg, Viktoria, Eivers, Luke, Wange, Lucas E., Gold, Christoph, Kirchner, Marieluise, Muenchhoff, Maximilian, Hellmuth, Johannes C., Scherer, Clemens, Rubio-Acero, Raquel, Eser, Tabea, Deák, Flora, Puchinger, Kerstin, Kuhl, Niklas, Linder, Andreas, Saar, Kathrin, Tomas, Lukas, Schulz, Christian, Wieser, Andreas, Enard, Wolfgang, Kroidl, Inge, Geldmacher, Christof, von Bergwelt-Baildon, Michael, Keppler, Oliver T., Munschauer, Mathias, Iannacone, Matteo, Zimmer, Ralf, Mertins, Philipp, Hubner, Norbert, Hoelscher, Michael, Massberg, Steffen, Stark, Konstantin, Nicolai, Leo
    Publicado 2022
    “…We see a distinct systemic rather than local immune state associated with viral containment, characterized by interferon stimulated gene (ISG) upregulation across circulating immune cell subsets in non-pneumonic SARS-CoV2 infection. …”
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    Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection
  5. 29625
    “…IgG and IgM SARS-CoV-2 antibodies, Interleukin 1b (IL1b), Interleukin 6 (IL6), and gamma-Interferon (IFN-γ), have been studied in the UCB samples. …”
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    Transmitted Fetal Immune Response in Cases of SARS-CoV-2 Infections during Pregnancy
  6. 29626
    “…Rhesus macaques immunized with a ΔE4(1) Ad that expressed rhFLSC (HIV-1(BaL) gp120 linked to rhesus CD4 D1 and D2), exhibited higher levels of rhFLSC-specific interferon γ-producing memory T-cells, higher titers of rhFLSC-specific IgG1 binding antibody in serum, and antibodies able to mediate antibody-dependent cellular cytotoxicity (ADCC) with greater killing capacity than the ΔE1B Ad. …”
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    E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses
  7. 29627
    “…Background and Objectives: Assessment of RANTES level and concentrations of inflammatory cytokines: programmed death ligand 1 (PD-L1), interferon gamma IFN-γ, tumor necrosis factor alpha (TNF-α), transforming growht factor β (TGF-β) (and angiogenesis factors: vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor C (VEGF C) in tumor and margin tissues of colorectal cancer (CRC,) and evaluation of RANTES influence on histopathological parameters (microvessel density (MVD), budding, tumor-infiltrating lymphocytes (TILs)), in relation to patients’ clinical features. …”
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    Assessment of the RANTES Level Correlation and Selected Inflammatory and Pro-Angiogenic Molecules Evaluation of Their Influence on CRC Clinical Features: A Preliminary Observational Study
  8. 29628
    “…Latest molecular-based diagnostic modalities such as GeneXpert, interferon-gamma (IFN-γ) release assays (IGRA), polymerase chain reaction (PCR), multiplex-PCR, and immunological markers are expected to help diagnose intestinal tuberculosis. …”
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    Recent advances in the diagnosis of intestinal tuberculosis
  9. 29629
    “…COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung pathology and extrapulmonary complications(1,2). Type I interferons (IFNs) have an essential role in the pathogenesis of COVID-19 (refs (3–5)). …”
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    The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
  10. 29630
    “…Additionally, we validated that these DCs retain their specific characteristics, both at the level of phenotype and interferon gamma secretion. Evaluating their functional characteristics, we demonstrate that PD-L silencing does not affect the capacity to induce allogeneic proliferation. …”
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    Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by In Situ Silencing of Programmed-Death Ligands
  11. 29631
    “…All c-Met CARs were stably expressed on T cell membrane, and c-Met CAR-T cells aggregated around c-Met-positive HCC cells and specifically killed them in vitro. c-Met-28-137-3ζ CAR-T cells secreted more interferon-gamma (IFN-γ) and interleukin 2 (IL-2) than c-Met-28-3ζ CAR-T cells and c-Met-137-3ζ CAR-T cells. …”
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    c-Met-targeted chimeric antigen receptor T cells inhibit hepatocellular carcinoma cells in vitro and in vivo
  12. 29632
    “…The levels of colony-stimulating factor (CSF)-1, interleukin (IL)-34, tumour necrosis factor (TNF)-α, interferon-γ-induced protein (IP)-10, monocyte chemoattractant protein (MCP)-1, calprotectin, macrophage inflammatory protein (MIP)-1α and MIP-1β were analysed by immunoassays and related to DA. …”
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    Inflammatory markers in saliva and urine reflect disease activity in patients with systemic lupus erythematosus
  13. 29633
    “…Different kinds of inflammatory and immune cells such as macrophages, fibroblasts, and T cells play key roles in the development of RILI, and transforming growth factor-β (TGF-β), interleukin-4 (IL-4), IL-13, and interferon-γ (IFN-γ) are also participants in this process. …”
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    Exploration of radiation-induced lung injury, from mechanism to treatment: a narrative review
  14. 29634
    “…The FSS treatment also enhanced the expression of the cytokines tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), and interferon gamma (IFN-γ), which are necessary for sustained T cell activation and function. …”
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    Fluid shear stress enhances T cell activation through Piezo1
  15. 29635
    “…For pediatric AR patients only, serum interferon‐gamma (IFN‐γ) and interleukin (IL)‐10 were measured by enzyme linked immunosorbent assay; meanwhile, T helper (Th) 1 and Th2 cells in CD4(+) T cells were analyzed by flow cytometry. …”
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    Aberrant expressions of circulating lncRNA NEAT1 and microRNA‐125a are linked with Th2 cells and symptom severity in pediatric allergic rhinitis
  16. 29636
    “…Treatment with budigalimab was associated with increases in multiple soluble biomarkers including interferon gamma-induced chemokines. Expanded overall T-cell counts, total CD8 T-cell counts, and percentages of CD8(+)CD45RA(–)CD62L(–) effector memory T cells were observed at cycle 1, day 15 in responders. …”
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    Association of Baseline and Pharmacodynamic Biomarkers With Outcomes in Patients Treated With the PD-1 Inhibitor Budigalimab
  17. 29637
    “…In addition, serum interleukin 4 (IL-4), interferon-γ (IFN-γ), immunoglobulin E (IgE), IL-13, and TSLP levels were measured using enzyme-linked immunosorbent assay (ELISA), while tissue IL-13 and TSLP levels were assessed using ELISA, Western blotting, and immunohistochemical staining, and mast cell infiltration was assessed through toluidine blue (TBO) staining. …”
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    Polyinosinic:polycytidylic acid aggravates calcipotriol-induced atopic dermatitis-like skin lesions in mice by increasing the expression of thymic stromal lymphopoietin
  18. 29638
    “…Surprisingly, gene expression associated with type I and type II interferon activity, critical to the innate response to bacterial and viral infections, differed following supplementation with either vitamin D(2) or vitamin D(3), with only vitamin D(3) having a stimulatory effect. …”
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    Vitamins D(2) and D(3) Have Overlapping But Different Effects on the Human Immune System Revealed Through Analysis of the Blood Transcriptome
  19. 29639
    “…A major advance has been achieved with the discovery of the next generation maturation protocol involving TLR-3 agonist (poly I:C), tumor necrosis factor (TNF)-α, interleukin (IL)-1β, interferon (IFN)-γ, and IFN-α, and has since been known as α-type-1 maturation cocktail. …”
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    Combined TLR-3/TLR-8 Signaling in the Presence of α-Type-1 Cytokines Represents a Novel and Potent Dendritic Cell Type-1, Anti-Cancer Maturation Protocol
  20. 29640
    “…Signal transducer and activator of transcription 1 (STAT1) and 3 (STAT3) are key transcription factors activated by pro-inflammatory cytokines such as interferon-γ (IFN-γ) and interleukin-6 (IL-6). In this study, we combined in vitro cell culture experiments and immunohistochemical analyses of human HCC (N = 124) and CCA (N = 138) specimens. …”
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    STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma
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