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29721por Han, Dae Hee, Kim, Woon-ki, Lee, Cheonghoon, Park, SungJun, Lee, Kiuk, Jang, Sung Jae, Ko, GwangPyo“…Additionally, pro-inflammatory cytokines, such as interferon-gamma, interleukin (IL)-2, IL-6, IL-17A, and TNF were significantly decreased, while IL-10, an anti-inflammatory cytokine, was increased. …”
Publicado 2022
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29722“…Inflammatory cytokines, tumor necrosis factor α (TNF-α), interleukin 1β (IL-1β), IL-6, IL-8, IL-10, interferon γ (IFN-γ), were analyzed in serum. DNA was extracted from fecal samples to perform a 16S rRNA metagenomics analysis. …”
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29723por Cook, Joselle, Peng, Kah-Whye, Witzig, Thomas E., Broski, Stephen M., Villasboas, Jose C., Paludo, Jonas, Patnaik, Mrinal, Rajkumar, Vincent, Dispenzieri, Angela, Leung, Nelson, Buadi, Francis, Bennani, Nora, Ansell, Stephen M., Zhang, Lianwen, Packiriswamy, Nandakumar, Balakrishnan, Baskar, Brunton, Bethany, Giers, Marissa, Ginos, Brenda, Dueck, Amylou C., Geyer, Susan, Gertz, Morie A., Warsame, Rahma, Go, Ronald S., Hayman, Suzanne R., Dingli, David, Kumar, Shaji, Bergsagel, Leif, Munoz, Javier L., Gonsalves, Wilson, Kourelis, Taxiarchis, Muchtar, Eli, Kapoor, Prashant, Kyle, Robert A., Lin, Yi, Siddiqui, Mustaqeem, Fonder, Amie, Hobbs, Miriam, Hwa, Lisa, Naik, Shruthi, Russell, Stephen J., Lacy, Martha Q.“…A single IV dose of vesicular stomatitis virus (VSV) interferon-β (IFN-β) with sodium iodide symporter (NIS) was administered to patients with relapsed/refractory hematologic malignancies to determine safety and efficacy across 4 dose levels (DLs). …”
Publicado 2022
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29724por Ortega, Marina Mazzilli, da Silva, Laís Teodoro, Candido, Érika Donizetti, Zheng, Yingying, Tiyo, Bruna Tiaki, Ferreira, Arthur Eduardo Fernandes, Corrêa-Silva, Simone, Scagion, Guilherme Pereira, Leal, Fabyano Bruno, Chalup, Vanessa Nascimento, Valério, Camila Araújo, Schmitz, Gabriela Justamante Händel, Ceneviva, Carina, Corá, Aline Pivetta, de Almeida, Alexandre, Durigon, Edison Luiz, Oliveira, Danielle Bruna Leal, Palmeira, Patricia, da Silva Duarte, Alberto José, Carneiro-Sampaio, Magda, Oshiro, Telma Miyuki“…IgA and IgG antibodies directed at the spike protein were analysed in samples of saliva and/or serum by ELISA and/or chemiluminescence assays; the neutralizing activity of serum antibodies against reference strain B, Gamma and Delta SARS-CoV-2 variants were evaluated using a virus neutralization test and SARS-CoV-2 reactive interferon-gamma T-cell were analysed by flow cytometry. …”
Publicado 2022
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29725por Shi, Xuan, Wang, Sheng, Wu, Yutong, Li, Quanfu, Zhang, Tong, Min, Keting, Feng, Di, Liu, Meiyun, Wei, Juan, Zhu, Lina, Mo, Wei, Xiao, Zhuoran, Yang, Hao, Chen, Yuanli, Lv, Xin“…BACKGROUND AND AIMS: Cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) (cGAMP) synthase (cGAS) and stimulator of interferon genes (STING) are key components of the innate immune system. …”
Publicado 2022
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29726por van de Merbel, Arjanneke F., van der Horst, Geertje, van der Mark, Maaike H., Bots, Selas T. F., van den Wollenberg, Diana J. M., de Ridder, Corrina M. A., Stuurman, Debra, Aalders, Tilly, Erkens-Schulz, Sigrun, van Montfoort, Nadine, Karthaus, Wouter R., Mehra, Niven, Smits, Minke, Schalken, Jack A., van Weerden, Wytske M., Hoeben, Rob C., van der Pluijm, Gabri“…The infection induced the expression of mediators of immunogenic cell death, interferon-stimulated genes, and inflammatory cytokines. …”
Publicado 2021
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29727por Liu, Hainan, Bai, Yu, Zhang, Xun, Gao, Ting, Liu, Yue, Li, Entao, Wang, Xuefeng, Cao, Zheng, Zhu, Lin, Dong, Qincai, Hu, Yong, Wang, Guangfei, Song, Caiwei, Niu, Xiayang, Zheng, Tong, Wang, Di, Liu, Zijing, Jin, Yanwen, Li, Ping, Bian, Xiuwu, Cao, Cheng, Liu, Xuan“…Recent studies showed that NP antagonizes interferon (IFN) induction and mediates phase separation. …”
Publicado 2022
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29728por Khalil, Rehab G., Abdel-Moneim, Adel, Arafa, Amany A., Allam, Gamal, El-Senousy, Waled M., Mabrouk, Doaa“…Fasting blood sugar and hemoglobin A1c significantly increased in PD(+) compared to PD(−). Interferon-γ and interleukin (IL)-15 levels significantly increased. …”
Publicado 2022
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29729por Farag, Mayada R., Alagawany, Mahmoud, Khalil, Samah R., El-Hady, Eman W., Elhady, Walaa M., Ismail, Tamer Ahmed, Marini, Carlotta, Di Cerbo, Alessandro, Abdel-Latif, Hany M. R.“…Fish hematobiochemical parameters, serum immunity [nitric oxide, total immunoglobulin M (IgM) levels, and lysozyme activity], transcription of hepatic interferon-γ (IFN-γ), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α), and resistance to Aeromonas hydrophila (A. hydrophila) were assessed. …”
Publicado 2022
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29730“…Malignant phenotypes of HNSCCs are regulated by the pro- and anti-tumoral activities of the immune modulatory cytokines associated with TMEs, i.e., a representative pro-inflammatory cytokine, interferon (IFN)-γ, plays a role as an anti-tumor regulator against HNSCCs; however, IFN-γ also drives programmed death-ligand (PD-L) 1 expression to promote cancer stem cells. …”
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29731por Zhang, Wenjing, Tang, Yunfeng, Guo, Yuxian, Kong, Yujia, Shi, Fuyan, Sheng, Chao, Wang, Suzhen, Wang, Qinghua“…Genomic and immunologic analysis showed that a high mutational burden, increased infiltration of immune-response cells, decreased infiltration of immune-suppressive cells, interferon and cell cycle-related pathways were enriched in patients with FAT1 mutations. …”
Publicado 2022
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29732por Guedes, Diego Lins, da Silva, Elis Dionísio, Castro, Maria Carolina Accioly Brelaz, Júnior, Walter Lins Barbosa, Ibarra-Meneses, Ana Victoria, Tsoumanis, Achilleas, Adriaensen, Wim, van Griensven, Johan, Pereira, Valéria Rêgo Alves, de Medeiros, Zulma Maria“…Serum cytokine levels (interferon-γ, tumor necrosis factor, and interleukins 2, 4, 6, 10, and 17A) were quantified using the Becton Dickinson-BD’s Cytometric Bead Array (CBA) system. …”
Publicado 2022
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29733por Zhang, Yugui, Niu, Jiangtao, Zhang, Shujuan, Si, Xinlei, Bian, Tian-Tian, Wu, Hongwei, Li, Donghui, Sun, Yujing, Jia, Jing, Xin, Erdan, Yan, Xingke, Li, Yuefeng“…Gastrointestinal function including d-xylose, gastrin, amylase vasoactive intestinal peptide, motilin, pepsin, H(+)/K(+)-ATPase, Na(+)/K(+)-ATPase, sodium-glucose cotransporter 1 (SGLT1), glucose transporter 2 (GLUT2) and immune function including spleen and thymus index, blood routine, interleukin (IL)-2, IL-6, interferon-γ (IFN-γ), tumour necrosis factor-α (TNF-α), immunoglobulin (Ig) M, IgA, IgG and delayed-type hypersensitivity (DTH) were detected. …”
Publicado 2022
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29734“…OBJECTIVES: To investigate whether the levels of interleukin 1β (IL-1β), interferon γ (IFN-γ), tumor necrosis factor α (TNF-α) in children with Kawasaki disease (KD) are correlated with coronary artery lesion (CAL) and resistance to intravenous immunoglobulin (IVIG) treatment. …”
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29735por Tsai, Syun-Hui, Tseng, Yu-Hwei, Chiou, Wen-Fei, Chen, Shih-Ming, Chung, Yi, Wei, Wen-Chi, Huang, Wen-Ching“…The WBV intervention combined with the HFrD model significantly ameliorated weight gain, glucose intolerance, total cholesterol, and inflammatory cytokines (interferon gamma [IFN-γ], interleukin [IL]-17, and IL-4) in the OVX mice, although osteoporosis and liver steatosis were not affected compared to the negative control group. …”
Publicado 2022
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29736por Salama, Iman Ibrahim, Raslan, Hala M, Abdel-Latif, Ghada A, Salama, Somaia I, Sami, Samia M, Shaaban, Fatma A, Abdelmohsen, Aida M, Fouad, Walaa A“…The higher rate of hepatocellular carcinoma (HCC) after DAA therapy may be related to the fact that DAA regimens are offered to patients with advanced liver fibrosis and cirrhosis, where interferon was contraindicated to those patients. The change in the growth of pre-existing subclinical, undetectable HCC upon DAA treatment might be also a cause. …”
Publicado 2022
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29737por Davidovic, Tamara, Schimpf, Judith, Abbassi-Nik, Armin, Stockinger, Richard, Sprenger-Mähr, Hannelore, Lhotta, Karl, Zitt, Emanuel“…The cellular immune response was evaluated via SARS-CoV-2 spike protein-specific interferon-γ release assay. RESULTS: The seroconversion rate was 47.2%, 100%, 69.4% and 100% one month after the 1(st) dose, one and six months after the 2(nd) dose and four months after the heterologous 3(rd) dose. …”
Publicado 2022
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29738“…In current contact investigations, immunologic tests (the tuberculin skin test and interferon-gamma release assay) and chest X-ray examinations are used to dichotomize contacts with Mycobacterium tuberculosis infections into those with active (X-ray abnormalities) versus latent tuberculosis (normal radiographs). …”
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29739por Mick, Eran, Tsitsiklis, Alexandra, Spottiswoode, Natasha, Caldera, Saharai, Serpa, Paula Hayakawa, Detweiler, Angela M., Neff, Norma, Pisco, Angela Oliveira, Li, Lucy M., Retallack, Hanna, Ratnasiri, Kalani, Williamson, Kayla M., Soesanto, Victoria, Simões, Eric A. F., Smith, Christiana, Abuogi, Lisa, Kistler, Amy, Wagner, Brandie D., DeRisi, Joseph L., Ambroggio, Lilliam, Mourani, Peter M., Langelier, Charles R.“…To investigate whether differences in the upper airway immune response may contribute to this disparity, we compare nasopharyngeal gene expression in 83 children (<19-years-old; 38 with SARS-CoV-2, 11 with other respiratory viruses, 34 with no virus) and 154 older adults (>40-years-old; 45 with SARS-CoV-2, 28 with other respiratory viruses, 81 with no virus). Expression of interferon-stimulated genes is robustly activated in both children and adults with SARS-CoV-2 infection compared to the respective non-viral groups, with only subtle distinctions. …”
Publicado 2022
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29740por Adhikari, Bindu, Lee, Chin N., Khadka, Vedbar S., Deng, Youping, Fukumoto, Glen, Thorne, Mark, Caires, Kyle, Odani, Jenee, Mishra, Birendra“…The most highly up-regulated genes in the pregnant endometrium were MRS2, CST6, FOS, VLDLR, ISG15, IFI6, MX2, C15H11ORF34, EIF3M, PRSS22, MS4A8, and TINAGL1. Interferon signaling, immune response, nutrient transporter, synthesis, and secretion of proteins are crucial pathways during the maternal recognition of pregnancy. …”
Publicado 2022
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