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29781por van der Made, Caspar I., Netea, Mihai G., van der Veerdonk, Frank L., Hoischen, Alexander“…The current genetic findings point towards a convergence of common and rare genetic variants that impact the interferon signalling pathways in patients with severe or critical COVID-19. …”
Publicado 2022
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29782“…The current study intended to assess the relationship of Th1 cells, Th17 cells, interferon‐gamma (IFN‐γ), and interleukin (IL)‐17A with cognitive function in stroke patients. …”
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29783por Nishimura, Yuki, Iwashita, Misaki, Hayashi, Masato, Shinjo, Takanori, Watanabe, Yukari, Zeze, Tatsuro, Yamashita, Akiko, Fukuda, Takao, Sanui, Terukazu, Sano, Tomomi, Asano, Tomoichiro, Nishimura, Fusanori“…We previously demonstrated that macrophage-derived interferon (IFN) β induced X-linked inhibitor of apoptosis–associated factor 1 (XAF1) expression in β-cells and accelerated β-cell apoptosis in vitro. …”
Publicado 2022
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29784por Lamberti, María Julia, Montico, Barbara, Ravo, Maria, Nigro, Annunziata, Giurato, Giorgio, Iorio, Roberta, Tarallo, Roberta, Weisz, Alessandro, Stellato, Cristiana, Steffan, Agostino, Dolcetti, Riccardo, Casolaro, Vincenzo, Faè, Damiana Antonia, Dal Col, Jessica“…To this end, B cell lymphoma (Mino) and breast cancer (MDA-MB-231) cell lines were exposed to two different ICD inducers, the combination of retinoic acid (RA) and interferon-alpha (IFN-α) and doxorubicin, and to non ICD inducers such as gamma irradiation. …”
Publicado 2022
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29785por Campanati, Anna, Orciani, Monia, Marani, Andrea, Di Vincenzo, Mariangela, Magi, Simona, Gregoriou, Stamatios, Diotallevi, Federico, Martina, Emanuela, Radi, Giulia, Offidani, Annamaria“…C- and AD-MSCs (T0, T16) were isolated from skin specimens and characterized; the expression/secretion of IL4 and IL13 was evaluated using immuno-cytochemistry (ICC), indirect immune-fluorescence (IIF) and an ELISA test; secretion of IL2, IL4, IL5, IL6, IL10, IL12, IL13, IL17A, Interferon gamma (IFNγ), Tumor necrosis factor alpha (TNFα), Granulocyte Colony-Stimulating Factor (G-CSF), and Transforming Growth Factor beta1 (TGFβ1) were measured with ELISA. …”
Publicado 2022
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29786por Fuchs, Claudia D., Dixon, Emmanuel D., Hendrikx, Tim, Mlitz, Veronika, Wahlström, Annika, Ståhlman, Marcus, Scharnagl, Hubert, Stojakovic, Tatjana, Binder, Christoph J., Marschall, Hanns‐Ulrich, Trauner, Michael“…In vitro, the THBA effect on chenodeoxycholic acid (CDCA)–induced inflammatory signaling in hepatocyte and cholangiocytes as well as lipopolysaccharide (LPS)/interferon‐γ (IFN‐γ)–induced macrophage activation was analyzed. …”
Publicado 2022
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29787“…LIST OF ABBREVIATIONS: EMBL-EBI The European Bioinformatics Institute; E. coli Escherichia coli; E. faecalis Enterobacter faecalis; B. fragilis Bacteroides fragilis; B. vulgatus Bacteroides vulgatus; SaPIs Staphylococcus aureus pathogenicity islands; ARGs Antibiotic resistance genes; STEC Shiga toxigenic E. coli; Stx Shiga toxin; BLAST Basic Local Alignment Search Tool; TSST-1 Toxic shock toxin 1; RBPs Receptor-binding proteins; LPS lipopolysaccharide; OMVs Outer membrane vesicles; PT Phosphorothioate; BREX Bacteriophage exclusion; OCR Overcome classical restriction; Pgl Phage growth limitation; DISARM Defense island system associated with restrictionmodification; R-M system Restriction-modification system; BREX system Bacteriophage exclusion system; CRISPR Clustered regularly interspaced short palindromic repeats; Cas CRISPR-associated; PAMs Prospacer adjacent motifs; crRNA CRISPR RNA; SIE; OMPs; Superinfection exclusion; Outer membrane proteins; Abi Abortive infection; TA Toxin-antitoxin; TLR Toll-like receptor; APCs Antigen-presenting cells; DSS Dextran sulfate sodium; IELs Intraepithelial lymphocytes; FMT Fecal microbiota transfer; IFN-γ Interferon-gamma; IBD Inflammatory bowel disease; AgNPs Silver nanoparticles; MDSC Myeloid-derived suppressor cell; CRC Colorectal cancer; VLPs Virus-like particles; TMP Tape measure protein; PSMB4 Proteasome subunit beta type-4; ALD Alcohol-related liver disease; GVHD Graft-versus-host disease; ROS Reactive oxygen species; RA Rheumatoid arthritis; CCP Cyclic citrullinated protein; AMGs Accessory metabolic genes; T1DM Type 1 diabetes mellitus; T2DM Type 2 diabetes mellitus; SCFAs Short-chain fatty acids; GLP-1 Glucagon-like peptide-1; A. baumannii Acinetobacter baumannii; CpG Deoxycytidylinate-phosphodeoxyguanosine; PEG Polyethylene glycol; MetS Metabolic syndrome; OprM Outer membrane porin M.…”
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29788por Feng, Bo, Yang, Rui-Feng, Zhang, Hai-Ying, Luo, Bi-Fen, Kong, Fan-Yun, Rao, Hui-Ying, Jin, Qian, Cong, Xu, Wei, Lai“…We evaluated early predictive efficacy of serum hepatitis C virus core antigen kinetics on sustained virologic response in patients with genotype 1 hepatitis C virus during pegylated interferon plus ribavirin treatment. For 478 patients recruited, hepatitis C virus RNAs were detected at baseline, and at weeks 4, 12, 24, 48, and 72 using Cobas TaqMan. …”
Publicado 2015
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29789por Yu, Zhenfeng, Vepris, Olena, Eich, Christina, Feng, Yansong, Que, Ivo, Camps, Marcel G. M., Zhang, Hong, Ossendorp, Ferry A., Cruz, Luis J.“…In vitro experiments demonstrated that OVA24-Pam3CSK4-UCNPs induced a strong immune response, including DC maturation, T cell activation, and proliferation, as well as interferon gamma (IFN-γ) production. In vivo, highly sensitive upconversion luminescence (UCL) imaging of OVA24-Pam3CSK4-UCNPs allowed tracking of UCNPs from the periphery to lymph nodes. …”
Publicado 2022
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29790por García-Abellán, Javier, Fernández, Marta, Padilla, Sergio, García, José Alberto, Agulló, Vanesa, Lozano, Valle, Ena, Nuria, García-Sánchez, Lidia, Gutiérrez, Félix, Masiá, Mar“…T-cell immune response measured with a SARS-CoV-2-interferon-γ release assay was not different between groups. …”
Publicado 2022
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29791“…Broilers fed a PAL-supplemented diet exerted decreased contents of interferon-γ (IFN-γ) and interleukin-1β in serum, and the same reduction was found in jejunal IFN-γ level, when compared to the CON group (P < 0.05). …”
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29792por Ferrante, Nicole D, Newcomb, Craig W, Forde, Kimberly A, Leonard, Charles E, Torgersen, Jessie, Linas, Benjamin P, Rowan, Sarah E, Wyles, David L, Kostman, Jay, Trooskin, Stacey B, Lo Re, Vincent“…In the pre-direct-acting antiviral (DAA) era, it was estimated that 50% of HCV-infected individuals were diagnosed and that 16% had been prescribed interferon-based therapy. Since then, few studies utilizing nationally representative data from the DAA era have been conducted in the United States. …”
Publicado 2022
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29793por Al-Ansari, Mysoon M., Aleidi, Shereen M., Masood, Afshan, Alnehmi, Eman A., Abdel Jabar, Mai, Almogren, Maha, Alshaker, Mohammed, Benabdelkamel, Hicham, Abdel Rahman, Anas M.“…A network pathway analysis of the differentially abundant proteins demonstrated dysregulation of inflammatory signaling pathways in the LBMD patients, including the tumor necrosis factor (TNF), toll-like receptor (TL4), and interferon-γ (IFNG) signaling pathways. These results reveal the existence of potentially sensitive protein biomarkers that could be used in further investigations of bone health and OP progression.…”
Publicado 2022
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29794por Liu, Mingjiang, Liu, Tengwen, Wang, Xuerui, Yu, Chenglong, Qin, Tao, Li, Jingui, Zhang, Mina, Li, Zhenxuan, Cui, Xuran, Xu, Xiaolong, Liu, Qingquan“…We revealed that the oral administration of CMHD granules protects mice against higher mortality, enhanced weight loss, overwhelmed interferon-γ concentration, lung viral titers, and severe lung pathological injury in PR8-infected mice. …”
Publicado 2022
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29795por Renaudineau, Yves, Sailler, Laurent, Abravanel, Florence, Izopet, Jacques, Delourme, Adrien, Biotti, Damien, Ciron, Jonathan, Treiner, Emmanuel, Congy-Jolivet, Nicolas, Bost, Chloé, Blancher, Antoine“…We performed a whole blood interferon gamma release assay using SARS-Cov2 Spike and Nucleocapsid recombinant proteins in order to evaluate T-cell memory response, and an IgG anti-Spike ELISA to evaluate humoral response. …”
Publicado 2022
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29796por Huisman, Wesley, Gille, Ilse, van der Maarel, Lieve E, Hageman, Lois, Morton, Laura T, de Jong, Rob C M, Heemskerk, Mirjam H M, Amsen, Derk, Falkenburg, J H Frederik, Jedema, Inge“…Functionality was assessed by production of interferon gamma (IFN-γ) and cytotoxicity when stimulated with EBV-LMP2–expressing cell lines. …”
Publicado 2020
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29797por Gragnani, Laura, Visentini, Marcella, Lorini, Serena, La Gualana, Francesca, Santini, Stefano Angelo, Cacciapaglia, Fabio, Tavoni, Antonio, Cuomo, Giovanna, Fallahi, Poupak, Iannone, Florenzo, Antonelli, Alessandro, Casato, Milvia, Zignego, Anna Linda, Ferri, Clodoveo“…PATIENTS AND METHODS: Serum NAb titer and T-cell response (measuring interferon gamma –IFN–γ- release) were evaluated 3 weeks after the COVID-19 vaccine booster dose, in 17 patients (12 F, mean age 68.8 ± 15.3 SD yrs) with different ASDs, compared to 17 healthy controls (HCs). …”
Publicado 2022
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29798por Woodburn, Blaide M., Kanchi, Krishna, Zhou, Shuntai, Colaianni, Nicholas, Joseph, Sarah B., Swanstrom, Ronald“…In this study, we utilize macrophage-tropic and T cell-tropic HIV-1 Env proteins to establish accurate infection profiles for multiple CNS cells under basal and interferon alpha (IFN-α) or lipopolysaccharide (LPS)-induced inflammatory states. …”
Publicado 2022
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29799por Han, Yu, Bai, Xue, Liu, Siying, Zhu, Jingfei, Zhang, Fan, Xie, Lifen, Liu, Guodi, Jiang, Xiaohui, Zhang, Mingchao, Huang, Yingkang, Wang, Jingfeng, Li, Dapei, Zhang, Huiying, He, Yuanqing, He, Sudan, Xia, Yu, Xu, Xiulong, Xu, Feng, Ma, Feng“…XIAP-associated factor 1 (XAF1) is an interferon (IFN)-stimulated gene (ISG) that enhances IFN-induced apoptosis. …”
Publicado 2022
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29800“…Cells exhibiting strong interferon/cytokine responses were found to be associated with the severity of COVID-19. …”
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