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29841por Zaazaa, Ahmed, Mudalal, Samer, Alzuheir, Ibrahim, Samara, Maen, Jalboush, Nasr, Fayyad, Adnan, Petracci, Massimiliano“…The thyme and oregano oil diets showed no significant differences in antibody titers against Newcastle disease or interferon-γ (INF-γ) serum levels. In conclusion, thyme and oregano oils had a positive impact on the growth performance of broiler chickens but increased the incidence of growth-related breast muscle abnormalities.…”
Publicado 2022
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29842por Azzinaro, Paul A., Medina, Gisselle N., Rai, Devendra, Ramirez-Medina, Elizabeth, Spinard, Edward, Rodriguez-Calzada, Monica, Zhu, James, Rieder, Elizabeth, de los Santos, Teresa, Díaz-San Segundo, Fayna“…Western blot analysis on protein extracts from these cells, revealed that while processing of translation initiation factor eIF-4G was slightly delayed, no degradation of innate sensors or effector molecules such as NF-κB or G3BP2 was observed, and higher levels of interferon (IFN) and IFN-stimulated genes (ISGs) were induced after infection with A12-L(H138L) as compared to WT FMDV. …”
Publicado 2022
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29843por de Castro, Mateus V., Silva, Monize V. R., Naslavsky, Michel S., Scliar, Marilia O., Nunes, Kelly, Passos-Bueno, Maria Rita, Castelli, Erick C., Magawa, Jhosiene Y., Adami, Flávia L., Moretti, Ana I. S., de Oliveira, Vivian L., Boscardin, Silvia B., Cunha-Neto, Edecio, Kalil, Jorge, Jouanguy, Emmanuelle, Bastard, Paul, Casanova, Jean-Laurent, Quiñones-Vega, Mauricio, Sosa-Acosta, Patricia, de Guedes, Jéssica S., de Almeida, Natália P., Nogueira, Fábio C. S., Domont, Gilberto B., Santos, Keity S., Zatz, Mayana“…None presented autoantibodies (auto-Abs) to type I interferon (IFN). Furthermore, these supercentenarians do not carry rare variants in genes underlying the known inborn errors of immunity, including particular inborn errors of type I IFN. …”
Publicado 2022
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29844“…Iterative scrutinization lead to the identification of two highly antigenic, virulent, non-allergic, non-toxic, water soluble, and Interferon-gamma inducer epitopes i.e. HYITENYRN and TTSPVRENY. …”
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29845por Mattiesing, Rozemarijn M., Gentile, Giordano, Brouwer, Iman, van Schijndel, Ronald A., Uitdehaag, Bernard M.J., Twisk, Jos W.R., Kappos, Ludwig, Freedman, Mark S., Comi, Giancarlo, Jack, Dominic, De Stefano, Nicola, Barkhof, Frederik, Battaglini, Marco, Vrenken, Hugo“…Patients received early treatment (from baseline; N = 262) or delayed treatment (from month-24; N = 130) with subcutaneous interferon beta-1a. Global and central atrophy were assessed using FSL-SIENA to provide yearly percentage volume change of brain and ventricles, respectively. …”
Publicado 2022
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29846por Marín-Prida, Javier, Pavón-Fuentes, Nancy, Lagumersindez-Denis, Nielsen, Camacho-Rodríguez, Hanlet, García-Soca, Ana Margarita, Sarduy-Chávez, Rocío de la Caridad, Vieira, Érica Leandro Marciano, Carvalho-Tavares, Juliana, Falcón-Cama, Viviana, Fernández-Massó, Julio Raúl, Hernández-González, Ignacio, Martínez-Donato, Gillian, Guillén-Nieto, Gerardo, Pentón-Arias, Eduardo, Teixeira, Mauro Martins, Pentón-Rol, Giselle“…Phycocyanobilin (PCB), a chromophore of the biliprotein C-Phycocyanin (C-PC) from Spirulina platensis, has antioxidant, immunoregulatory and anti-inflammatory effects in this disease, and it could complement the effect of other Disease Modifying Treatments (DMT), such as Interferon-β (IFN-β). Here, our main goal was to evaluate the potential PCB benefits and its mechanisms of action to counteract the chronic EAE in mice. …”
Publicado 2022
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29847por Hui, Xianfeng, Yu, Xiao, Huang, Kun, Xu, Ting, Cao, Lei, Zhang, Yufei, Zhao, Lianzhong, Zhao, Ya, Lv, Changjie, Feng, sheng, Jiang, Yongzhong, Liu, Linlin, Jin, Meilin“…Mechanistically, 3-indoleacetonitrile promoted the host interferon signalling pathway response and inhibited autophagic flux. …”
Publicado 2023
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29848por Zhang, Fangbo, Guo, Feifei, Zhang, Yi, Xu, He, Liu, Yuling, Lin, Longfei, Li, Hui, Yang, Hongjun, Huang, Luqi“…Animal experiments demonstrated that HSBD protected the lung tissue from LPS-induced injury, and inhibited the levels of inflammatory cytokines such as interleukin (IL)-1β, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon (IFN)-γ and tumor necrosis factor (TNF)-α in the serum and IL-1β, IL-5, IL-6, IL-18, GM-CSF, IFN-γ and TNF-α in the lung tissue. …”
Publicado 2023
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29849por Velasco-Arnaiz, Eneritz, Batllori, Marta, Monsonís, Manuel, Valls, Anna, Ríos-Barnes, María, Simó-Nebot, Sílvia, Gamell, Anna, Fortuny, Clàudia, Tebruegge, Marc, Noguera-Julian, Antoni“…Interferon-gamma release assays performance can be impaired by host-related, technical and environmental factors, but data in young children are limited. …”
Publicado 2022
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29850por Wang, Zhaohuan, Tuo, Xiaopeng, Zhang, Junshi, Chai, Keli, Tan, Juan, Qiao, Wentao“…However, the effect of host cytokines on FV replication requires further investigation. Although interferon induced transmembrane (IFITMs) proteins have become the focus of antiviral immune response research due to their broad-spectrum antiviral ability, it remains unclear whether IFITMs can affect FV replication. …”
Publicado 2022
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29851por Ortega, Javier, de Juan, Lucia, Sevilla, Iker A., Garrido, Joseba M., Roy, Álvaro, Velasco, Carlos, Romero, Beatriz, Domínguez, Mercedes, Pérez de Val, Bernat, Nebot, Carolina, Sáez-Llorente, José Luis, Álvarez, Julio, Bezos, Javier“…All the animals were subjected to the single and comparative intradermal tuberculin (SIT and CIT, respectively) tests, interferon-gamma release assay (IGRA) and P22 ELISA. …”
Publicado 2022
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29852por Özcengiz, Erkan, Keser, Duygu, Özcengiz, Gülay, Çelik, Gözde, Özkul, Aykut, İnçeh, Fatma Nur“…These also induced highly neutralizing antibodies and elicited significant cell‐mediated immunity as demonstrated by enhanced antigen‐specific levels of interferon‐γ (INF‐γ) in the splenocytes of immunized mice. …”
Publicado 2022
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29853por Noll, Christina, Hiltensperger, Michael, Aly, Lilian, Wicklein, Rebecca, Afzali, Ali Maisam, Mardin, Christian, Gasperi, Christiane, Berthele, Achim, Hemmer, Bernhard, Korn, Thomas, Knier, Benjamin“…RESULTS: Rarefication of the superficial vascular complex occured during RRMS and was linked to higher frequencies of activated B cells and higher levels of the pro-inflammatory cytokines interferon-γ, tumor necrosis factor α and interleukin-17 in the cerebrospinal fluid. …”
Publicado 2022
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29854por Muñiz-Banciella, María G., Albaiceta, Guillermo M., Amado-Rodríguez, Laura, del Riego, Estefanía Salgado, Alonso, Inés López, López-Martínez, Cecilia, Martín-Vicente, Paula, García-Clemente, Marta, Hermida-Valverde, Tamara, Enríquez-Rodriguez, Ana I., Hernández-González, Cristina, Cuesta-Llavona, Elías, Alvarez, Victoria, Gómez, Juan, Coto, Eliecer“…MDA5, encoded by the IFIH1gene, is a cytoplasmic sensor of viral RNAs that triggers interferon (IFN) antiviral responses. Common and rare IFIH1 variants have been associated with the risk of type 1 diabetes and other immune-mediated disorders, and with the outcome of viral diseases. …”
Publicado 2022
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29855por Zhao, Xin, Cohen, Ezra E. W., William, William N., Bianchi, Joy J., Abraham, Jim P., Magee, Daniel, Spetzler, David B., Gutkind, J. Silvio, Alexandrov, Ludmil B., Cavenee, Webster K., Lippman, Scott M., Davoli, Teresa“…Somatic copy number alterations (SCNAs), generally (1) losses containing interferons and interferon-pathway genes, many on chromosome 9p, predict immune-cold, immune checkpoint therapy (ICT)-resistant tumors (2); however, genomic regions mediating these effects are unclear and probably tissue specific. …”
Publicado 2022
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29856por Michalak-Stoma, Anna, Bartosińska, Joanna, Raczkiewicz, Dorota, Kowal, Małgorzata, Kozak, Joanna, Gujski, Mariusz, Krasowska, Dorota, Chodorowska, Grażyna“…Granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon gamma (IFN-gamma), interleukin (IL)-1 beta, IL-2, Il-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-13, IL-17A, IL-18, IL-21, IL-22, IL-23, IL-27, and tumor necrosis factor (TNF)-alpha were measured in patients’ serum with a Th1/Th2/Th9/Th17/Th22/Treg Cytokine 18-Plex Human ProcartaPlex Panel, based on Luminex xMAP technology. …”
Publicado 2022
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29857por Wang, Zuo, Zhao, Yuan, Lan, Xinyi, He, Jianhua, Wan, Fachun, Shen, Weijun, Tang, Shaoxun, Zhou, Chuanshe, Tan, Zhiliang, Yang, Yanming“…Besides, the 0.9% TA inclusion lessened (P < 0.05) the concentrations of glucagon and TNF-α, but enhanced (P < 0.05) the interferon gamma (IFN-γ) level and Simpson index of ruminal bacteria. …”
Publicado 2022
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29858por Waleczek, F. J. G., Sansonetti, M., Xiao, K., Jung, M., Mitzka, S., Dendorfer, A., Weber, N., Perbellini, F., Thum, T.“…Such conditions were generated by applying interferon-gamma (IFN-γ) or interleukine-4 (IL-4) and altering the preload of cultured LMS, respectively. …”
Publicado 2022
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29859por Pernaa, Nora, Keskitalo, Salla, Chowdhury, Iftekhar, Nissinen, Antti, Glumoff, Virpi, Keski-Filppula, Riikka, Junttila, Juhani, Eklund, Kari K., Santaniemi, Wenny, Siitonen, Sanna, Seppänen, Mikko RJ., Vähäsalo, Paula, Varjosalo, Markku, Åström, Pirjo, Hautala, Timo“…Inflammasome activity, transcription of genes related with JAK/STAT pathway and interferon signature were also comparable to controls. …”
Publicado 2022
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29860por Sánchez-Zapardiel, Elena, Alós, María, Nozal, Pilar, González-Muñoz, Miguel, Frauca-Remacha, Esteban, Gavilán, Lucía Blanca, Quiles, María José, Hierro, Loreto, López-Granados, Eduardo“…Humoral responses were measured by fluoroenzyme-immunoassay and T-cell responses by interferon-γ-release assay. Post-vaccine coronavirus disease (COVID-19) events were recorded by a survey. …”
Publicado 2022
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