-
29981por Wright, Matthew L., Goin, Dana E., Smed, Mette Kiel, Jewell, Nicholas P., Nelson, J. Lee, Olsen, Jørn, Hetland, Merete Lund, Zoffmann, Vibeke, Jawaheer, Damini“…Adjusting for cell type proportions in our model revealed that although most of the expression changes were due to changes in cell type proportions in the bloodstream, transcriptional regulation was also involved, especially in down-regulating expression of type I interferon inducible genes. CONCLUSION: Compared to a pre-pregnancy baseline, there were extensive systemic changes in cell type proportions, gene expression and biological pathways associated with different stages of pregnancy and postpartum among healthy women. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29982por Hegdekar, Nivedita, Sarkar, Chinmoy, Bustos, Sabrina, Ritzel, Rodney M., Hanscom, Marie, Ravishankar, Prarthana, Philkana, Deepika, Wu, Junfang, Loane, David J., Lipinski, Marta M.“…In particular, we observed excessive activation of the innate immune responses, including both the type-I interferon and inflammasome pathways. Defects in microglial and macrophage autophagy following injury were associated with decreased phagocytic clearance of danger/damage-associated molecular patterns (DAMP) responsible for activation of the cellular innate immune responses. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29983por de Roquetaillade, Charles, Laouenan, Cédric, Mira, Jean-Paul, Roy, Carine, Thuong, Marie, Azoulay, Élie, Gruson, Didier, Jacobs, Frédéric, Chommeloux, Juliette, Raffi, François, Hocqueloux, Laurent, Imbert, Patrick, Jeantils, Vincent, Delassus, Jean-Luc, Matheron, Sophie, Fitting, Catherine, Timsit, Jean-François, Bruneel, Fabrice“…At hospital admission, eight blood cytokines were assayed in duplicate using Luminex(®) technology: interleukin (IL)-1α, IL-1β, IL-2, IL-4, IL-10, tumor necrosis factor (TNF)α, interferon (IFN)γ, and macrophage migration inhibitory factor (MIF). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29984por Subedi, Prabal, Huber, Katharina, Sterr, Christoph, Dietz, Anne, Strasser, Lukas, Kaestle, Felix, Hauck, Stefanie M., Duchrow, Lukas, Aldrian, Christine, Monroy Ordonez, Elsa Beatriz, Luka, Benedikt, Thomsen, Andreas R., Henke, Michael, Gomolka, Maria, Rößler, Ute, Azimzadeh, Omid, Moertl, Simone, Hornhardt, Sabine“…In silico pathway enrichment analysis predicted interferon (IFN) response and DNA strand elongation pathways as mostly affected pathways in both cell systems. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29985“…SIN significantly reduced the serum concentration of Tumor Necrosis Factor-α (TNF-α), Interleukin 1 Beta (IL-1β), Interleukin 6 (IL-6), Interferon gamma (IFN-γ), and C-X-C Motif Chemokine Ligand 8 (CXCL8), lowered the protein expression of phosphorylated c-Jun N-terminal kinase 1 (JNK1), JAK1, JAK2, STAT3, NF-κB, and decreased the proportion of cleaved-caspase3/caspase3. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29986por Tian, Xinrong, Wei, Yu, Hou, Runsu, Liu, Xinguang, Tian, Yange, Zhao, Peng, Li, Jiansheng“…The anti-inflammatory efficacy and molecular mechanisms of YCF were examined in a lipopolysaccharide (LPS)/interferon (IFN)-γ-induced macrophage inflammation model. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29987por Congrave-Wilson, Zion, Kim, Minjun, Sutherland, Aaron, Jumarang, Jaycee, Lee, Yesun, Del Valle, Jennifer, Cheng, Wesley A., Antunes, Ricardo Da Silva, Pannaraj, Pia S.“…SARS-CoV-2 spike-specific T cells were quantified and characterized via a flow cytometry-based activation induced markers (AIM) assay and an interferon-γ (IFNγ) FluoroSpot assay and responses were compared between processing methods. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29988por Wen, Sara Witting Christensen, Nederby, Line, Andersen, Rikke Fredslund, Hansen, Torben Schjødt, Nyhus, Christa Haugaard, Hilberg, Ole, Jakobsen, Anders, Hansen, Torben Frøstrup“…We used the NK Vue(®) assay to measure the level of interferon gamma (IFNγ) as a surrogate for NKA. Methylated HOXA9 was measured by droplet digital PCR. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29989“…The percentage of regulatory T cells and level of interferon gamma (IFN-γ) and transforming growth factor-beta (TGF-β) were evaluated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29990“…PATIENTS AND METHODS: This prospective cohort study compared laboratory markers (D-dimer, tumor necrosis factor-alpha [TNF-α], interferon-gamma [IFN-γ], C-reactive protein [CRP], lymphocyte and neutrophil counts) between COVID-19 patients and healthy controls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29991“…GO and GSVA analyses revealed that PI3K-Akt-mTOR and type I interferon signaling pathways were enriched in CD8(+) Tem and Trm cells after reinfection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29992por Ahn, So Yeon, Lee, Jueun, Lee, Dong-Ha, Ho, Thi Len, Le, Chau Thuy Tien, Ko, Eun-Ju“…A significant decrease in interferon-γ-producing T-cell populations and an increase in exhausted T-cell populations in the lungs of OVA-induced asthmatic mice were observed. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29993por Kitajima, Hiroshi, Maruyama, Reo, Niinuma, Takeshi, Yamamoto, Eiichiro, Takasawa, Akira, Takasawa, Kumi, Ishiguro, Kazuya, Tsuyada, Akihiro, Suzuki, Ryo, Sudo, Gota, Kubo, Toshiyuki, Mitsuhashi, Kei, Idogawa, Masashi, Tange, Shoichiro, Toyota, Mutsumi, Yoshido, Ayano, Kumegawa, Kohei, Kai, Masahiro, Yanagihara, Kazuyoshi, Tokino, Takashi, Osanai, Makoto, Nakase, Hiroshi, Suzuki, Hiromu“…TM4SF1-AS1 also activates interferon signaling in GC cells, which is dependent on Pur-α and RIG-I. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29994por Chuzho, Neihenuo, Mishra, Neetu, Tandon, Nikhil, Kanga, Uma, Mishra, Gunja, Sharma, Akanksha, Mehra, Narinder K., Kumar, Neeraj“…CD4 T cells' stimulation in terms of interferon‐gamma (IFN‐γ), interleukin (IL)‐17, tumor necrosis factor‐alpha (TNF‐α), and IL‐10 expression was analyzed using flow cytometry. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29995por Li, Wandi, Liu, Zhaopei, Jin, Kaifeng, Shao, Fei, Zeng, Han, Wang, Yiwei, Zhu, Yu, Xu, Le, Wang, Zewei, Chang, Yuan, Zhang, Weijuan“…VISTA(+) ICs infiltration shaped an immunoevasive context featured by regulatory T cells (Tregs), M2 macrophages, mast cells and exhausted CD8(+) T cells infiltration, with increased interleukin 10 (IL-10), transforming growth factor-β (TGF-β) and interferon-γ (IFN-γ), but also elevated T-cell immunoglobulin mucin-3 (TIM-3), lymphocyte activation gene 3 (LAG-3) and T-cell immunoglobulin and ITIM domain (TIGIT), which was also mainly presented in basal-squamous and luminal-infiltrated subtypes of MIBC. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29996por Hershkovich, Leeor, Shekhtman, Louis, Bazinet, Michel, Pântea, Victor, Placinta, Gheorge, Cotler, Scott J., Vaillant, Andrew, Dahari, Harel“…The early triple therapy group (n = 20) next received 48 weeks of TDF+pegylated interferon-α2a (pegIFN)+NAPs. In contrast, the delayed triple therapy group (n = 20) next received 24 weeks of TDF+pegIFN before 48 weeks of triple therapy. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29997“…Elevated serum levels of inflammatory cytokines, including interleukin (IL)-6, interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), confirmed the deranged type I immune responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29998por Wu, Wenxin, Zhang, Wei, Alexandar, Jeremy S., Booth, J. Leland, Miller, Craig A., Xu, Chao, Metcalf, Jordan P.“…RATIONALE: A family of short synthetic, triphosphorylated stem-loop RNAs (SLRs) have been designed to activate the retinoic-acid-inducible gene I (RIG-I) pathway and induce a potent interferon (IFN) response, which may have therapeutic potential. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
29999por Valentine, Gregory C., Seferovic, Maxim D., Fowler, Stephanie W., Major, Angela M., Gorchakov, Rodion, Berry, Rebecca, Swennes, Alton G., Murray, Kristy O., Suter, Melissa A., Aagaard, Kjersti M.“…The antibody was given to prevent the robust type I interferon signaling cascade that make mice inherently resistant to Zika virus infection. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30000por Min, Jin-Young, Kim, Jin Youp, Sung, Chung Man, Kim, Seon Tae, Cho, Hyun-Jin, Mun, Sue Jean, Cho, Sung-Woo, Hong, Sang Duk, Ryu, Gwanghui, Cho, Kyoung Rai, Kim, Young Hyo, Park, Soo Kyoung, Kim, Dong-Kyu, Lee, Dong Hoon, Heo, Sung Jae, Lee, Ki-Il, Kim, Su Jin, Lee, Sangjun, Mo, Ji-Hun, Shin, Seung-Heon, Kim, Dae Woo“…The endotypes of CRS were investigated by measuring interleukin (IL)-5, interferon (IFN)-γ, IL-17A, IL-22, IL-1β, IL-6, IL-8, matrix metalloproteinase-9, eotaxin-3, eosinophil cationic protein, myeloperoxidase (MPO), human neutrophil elastase (HNE), periostin, transforming growth factor-β1, total immunoglobulin E (IgE), and staphylococcal enterotoxin (SE)-specific IgE. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto