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  1. 29981
    “…Adjusting for cell type proportions in our model revealed that although most of the expression changes were due to changes in cell type proportions in the bloodstream, transcriptional regulation was also involved, especially in down-regulating expression of type I interferon inducible genes. CONCLUSION: Compared to a pre-pregnancy baseline, there were extensive systemic changes in cell type proportions, gene expression and biological pathways associated with different stages of pregnancy and postpartum among healthy women. …”
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    Pregnancy-associated systemic gene expression compared to a pre-pregnancy baseline, among healthy women with term pregnancies
  2. 29982
    “…In particular, we observed excessive activation of the innate immune responses, including both the type-I interferon and inflammasome pathways. Defects in microglial and macrophage autophagy following injury were associated with decreased phagocytic clearance of danger/damage-associated molecular patterns (DAMP) responsible for activation of the cellular innate immune responses. …”
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    Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes
  3. 29983
    “…At hospital admission, eight blood cytokines were assayed in duplicate using Luminex(®) technology: interleukin (IL)-1α, IL-1β, IL-2, IL-4, IL-10, tumor necrosis factor (TNF)α, interferon (IFN)γ, and macrophage migration inhibitory factor (MIF). …”
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    Cytokine profiles in adults with imported malaria
  4. 29984
    “…In silico pathway enrichment analysis predicted interferon (IFN) response and DNA strand elongation pathways as mostly affected pathways in both cell systems. …”
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    Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics
  5. 29985
    “…SIN significantly reduced the serum concentration of Tumor Necrosis Factor-α (TNF-α), Interleukin 1 Beta (IL-1β), Interleukin 6 (IL-6), Interferon gamma (IFN-γ), and C-X-C Motif Chemokine Ligand 8 (CXCL8), lowered the protein expression of phosphorylated c-Jun N-terminal kinase 1 (JNK1), JAK1, JAK2, STAT3, NF-κB, and decreased the proportion of cleaved-caspase3/caspase3. …”
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    Network pharmacology-based approach to explore the underlying mechanism of sinomenine on sepsis-induced myocardial injury in rats
  6. 29986
    “…The anti-inflammatory efficacy and molecular mechanisms of YCF were examined in a lipopolysaccharide (LPS)/interferon (IFN)-γ-induced macrophage inflammation model. …”
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    Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization
  7. 29987
    “…SARS-CoV-2 spike-specific T cells were quantified and characterized via a flow cytometry-based activation induced markers (AIM) assay and an interferon-γ (IFNγ) FluoroSpot assay and responses were compared between processing methods. …”
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    Effect of wash media type during PBMC isolation on downstream characterization of SARS-CoV-2-specific T cells
  8. 29988
    “…We used the NK Vue(®) assay to measure the level of interferon gamma (IFNγ) as a surrogate for NKA. Methylated HOXA9 was measured by droplet digital PCR. …”
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    NK cell activity and methylated HOXA9 ctDNA as prognostic biomarkers in patients with non-small cell lung cancer treated with PD-1/PD-L1 inhibitors
  9. 29989
    “…The percentage of regulatory T cells and level of interferon gamma (IFN-γ) and transforming growth factor-beta (TGF-β) were evaluated. …”
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    The effect of the anti-leukemia inhibitory factor on the immune system in the Balb/c mice bearing breast cancer induced with 4T1 cells
  10. 29990
    “…PATIENTS AND METHODS: This prospective cohort study compared laboratory markers (D-dimer, tumor necrosis factor-alpha [TNF-α], interferon-gamma [IFN-γ], C-reactive protein [CRP], lymphocyte and neutrophil counts) between COVID-19 patients and healthy controls. …”
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    Demographic, clinical and genetic factors associated with COVID-19 disease susceptibility and mortality in a Kurdish population
  11. 29991
    “…GO and GSVA analyses revealed that PI3K-Akt-mTOR and type I interferon signaling pathways were enriched in CD8(+) Tem and Trm cells after reinfection. …”
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    Comprehensive immune landscape of lung-resident memory CD8(+) T cells after influenza infection and reinfection in a mouse model
  12. 29992
    “…A significant decrease in interferon-γ-producing T-cell populations and an increase in exhausted T-cell populations in the lungs of OVA-induced asthmatic mice were observed. …”
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    Chronic allergic asthma induces T-cell exhaustion and impairs virus clearance in mice
  13. 29993
    “…TM4SF1-AS1 also activates interferon signaling in GC cells, which is dependent on Pur-α and RIG-I. …”
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    TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells
  14. 29994
    “…CD4 T cells' stimulation in terms of interferon‐gamma (IFN‐γ), interleukin (IL)‐17, tumor necrosis factor‐alpha (TNF‐α), and IL‐10 expression was analyzed using flow cytometry. …”
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    HLA‐DR3 mediated CD4 T cell response against GAD65 in type 1 diabetes patients
  15. 29995
    “…VISTA(+) ICs infiltration shaped an immunoevasive context featured by regulatory T cells (Tregs), M2 macrophages, mast cells and exhausted CD8(+) T cells infiltration, with increased interleukin 10 (IL-10), transforming growth factor-β (TGF-β) and interferon-γ (IFN-γ), but also elevated T-cell immunoglobulin mucin-3 (TIM-3), lymphocyte activation gene 3 (LAG-3) and T-cell immunoglobulin and ITIM domain (TIGIT), which was also mainly presented in basal-squamous and luminal-infiltrated subtypes of MIBC. …”
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    Immune inactivation by VISTA predicts clinical outcome and therapeutic benefit in muscle-invasive bladder cancer
  16. 29996
    “…The early triple therapy group (n = 20) next received 48 weeks of TDF+pegylated interferon-α2a (pegIFN)+NAPs. In contrast, the delayed triple therapy group (n = 20) next received 24 weeks of TDF+pegIFN before 48 weeks of triple therapy. …”
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    Rapid monophasic HBsAg decline during nucleic-acid polymer–based therapy predicts functional cure
  17. 29997
    “…Elevated serum levels of inflammatory cytokines, including interleukin (IL)-6, interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), confirmed the deranged type I immune responses. …”
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    Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome: A case report and review of literature
  18. 29998
    “…RATIONALE: A family of short synthetic, triphosphorylated stem-loop RNAs (SLRs) have been designed to activate the retinoic-acid-inducible gene I (RIG-I) pathway and induce a potent interferon (IFN) response, which may have therapeutic potential. …”
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    RIG-I agonist SLR10 promotes macrophage M1 polarization during influenza virus infection
  19. 29999
    “…The antibody was given to prevent the robust type I interferon signaling cascade that make mice inherently resistant to Zika virus infection. …”
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    Timing of gestational exposure to Zika virus is associated with postnatal growth restriction in a murine model
  20. 30000
    “…The endotypes of CRS were investigated by measuring interleukin (IL)-5, interferon (IFN)-γ, IL-17A, IL-22, IL-1β, IL-6, IL-8, matrix metalloproteinase-9, eotaxin-3, eosinophil cationic protein, myeloperoxidase (MPO), human neutrophil elastase (HNE), periostin, transforming growth factor-β1, total immunoglobulin E (IgE), and staphylococcal enterotoxin (SE)-specific IgE. …”
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    Inflammatory Endotypes of Chronic Rhinosinusitis in the Korean Population: Distinct Expression of Type 3 Inflammation
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