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30061por Yu, Shihan, Gu, Jia, Wang, Rui, Lee, Seunghyun, Shan, Yu, Wang, Jiakai, Sun, Yini, Ma, Xiaoxue“…OBJECTIVES: The induction direction of interferon (IFN)-α in T-cell phenotype and function varies depending on the activation state of the cell and the time of stimulation. …”
Publicado 2023
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30062“…Expression of tumor necrosis factor-α (TNF-α), interleukin (IL)-6, IL-1β, and interferon (IFN)-γ in lung tissue was determined by ELISA. q-PCR was used to detect nuclear factor kappa-B P65 (NF-κBP65). …”
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30063por Gaunt, Jessica R., Zainolabidin, Norliyana, Yip, Alaric K. K., Tan, Jia Min, Low, Aloysius Y. T., Chen, Albert I., Ch’ng, Toh Hean“…In WT mice, the expression of interferon-response genes in microglia is higher in the DCN than the EC and this enrichment is confirmed by RNA in situ hybridisation, and measurement of inflammatory cytokines by protein array. …”
Publicado 2023
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30064por Zhao, YiFan, Zhang, Yi, Lu, WenYi, Sun, Rui, Guo, RuiTing, Cao, XinPing, Liu, Xingzhong, Lyu, Cuicui, Zhao, MingFeng“…BACKGROUND: The Interferon-induced protein with tetratricopeptide repeat (IFIT) family, IFIT1/2/3/5, play an important role in different tumors progression. …”
Publicado 2023
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30065por Mairinger, Elena, Wessolly, Michael, Buderath, Paul, Borchert, Sabrina, Henrich, Larissa, Mach, Pawel, Steinborn, Julia, Kimming, Rainer, Jasani, Bharat, Schmid, Kurt Werner, Bankfalvi, Agnes, Mairinger, Fabian Dominik“…Activated downstream signaling cascades resulting in elevated interferon-gamma expression with a shift in the balance between T helper cells (T(H)1 and T(H)2) could be observed in the MT-positive subgroup. …”
Publicado 2023
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30066por Ryan, Eoin, Breslin, Philip, O’Keeffe, James, Byrne, Andrew W., Wrigley, Karina, Barrett, Damien“…Cattle which test inconclusive to the tuberculin skin test have been re-tested using a gamma interferon blood test since April 2021, enabling truly infected cattle to be identified more effectively due to the higher sensitivity of this test. …”
Publicado 2023
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30067por Kim, Seungil, Lee, Sohyeon, Kim, Tae-Young, Lee, Su-Hyun, Seo, Sang-Uk, Kweon, Mi-Na“…RESULTS: In this study, we screened various Lactobacillus (L.) strains for their ability to augment type I interferon (IFN-I) signaling using an IFN-α/β reporter cell line. …”
Publicado 2023
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30068por Zheng, Hui, Guan, Xiaolin, Meng, Xin, Tong, Ying, Wang, Yanchun, Xie, Suhong, Guo, Lin, Lu, Renquan“…BACKGROUND: Inflammation and immunity are two main characteristics of tumor microenvironment (TME). Interferon-gamma (IFN-γ) is generally considered as a pro-inflammatory cytokine which mediates anti-tumor immune response. …”
Publicado 2023
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30069“…In addition, the levels of Transforming growth factor-β, Interferon-gamma (IFN-γ), Interleukin IL-2, IL-10, IL-4, IL-12, and tumor necrosis factor (TNF)-α were determined. …”
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30070“…Furthermore, the concentration of interferon-gamma (IFN-γ), transforming growth factor-beta (TGF-β) and interleukin-10 (IL-10) was measured quantitatively using the enzyme-linked immunosorbent assay technique. …”
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30071por Zhou, Han, Wang, Lei, Lin, Zhiwen, Jiang, Chenwei, Chen, Xingte, Wang, Kai, Liu, Libin, Shao, Lingdong, Pan, Jianji, Li, Jinluan, Zhang, Da, Wu, Junxin“…Additionally, our study demonstrated that MG amplifies the RT-induced activation of the cyclic guanosine monophosphate AMP synthase-stimulator of interferon genes pathway by elevating DNA double-strand breaks. …”
Publicado 2023
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30072por Park, Hi Jung, Choi, Eun Ah, Choi, Sung Min, Choi, Young-Ki, Lee, Jae Il, Jung, Kyeong Cheon“…The relevant cytokines include interleukin-4 (IL-4), type I interferon, and interleukin-15 (IL-15). Moreover, exogenous IL-4 can also induce de novo generation and/or expansion of the virtual-memory CD8 T cell population. …”
Publicado 2023
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30073por Davuluri, Kusuma Sai, Singh, Amit Kumar, Yadav, Vimal Kumar, Singh, Ajay Vir, Singh, Shoor Vir, Chauhan, Devendra Singh“…Throughout the infection and treatment period, we measured the levels of Interleukin-12 subunit alpha (IL-12), Interferon-gamma (IFN-γ), TNF, Tumor growth factor (TGF), and T lymphocytes using ELISA. …”
Publicado 2023
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30074por Fang, Peng, Liu, Xiaozhou, Qiu, Yang, Wang, Yang, Wang, Dongsheng, Zhao, Jianning, Ding, Hao, Bao, Nirong“…RESULTS: The results suggest a genetically predicted potential association between beta-nerve growth factor (βNGF), Interleukin-1-beta (IL-1β), and TNF-related apoptosis inducing ligand (TRAIL) with the risk of AS (OR: 2.17, 95% CI: 1.13-4.16; OR: 0.41, 95% CI: 0.18-0.95,; OR: 1.47, 95% CI: 1.02-2.13).Additionally, Interleukin-12p70 (IL-12p70), Interleukin-17 (IL-17), Interleukin-6 (IL-6), Interleukin-4 (IL-4), Stromal-cell-derived factor 1 alpha (SDF−1α), Macrophage inflammatory protein 1β (MIP1β), Monocyte chemoattractant protein-3 (MCP-3), Platelet-derived growth factor bb (PDGFbb), Granulocyte-colony stimulating factor (GCSF), Fibroblast growth factor basic (bFGF), TNF-related apoptosis inducing ligand (TRAIL), and Interferon-gamma (IFN -γ) are suggested as consequences of AS in genetically prediction.No evidence of horizontal pleiotropy or heterogeneity between the genetic variants was found (P>0.05), and a leave-one-out test confirmed the stability and robustness of this association. …”
Publicado 2023
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30075por Luhm, Juergen, Langenkamp, Ulrich, Hensel, Jenny, Frohn, Christoph, Brand, Joerg M, Hennig, Holger, Rink, Lothar, Koritke, Petra, Wittkopf, Nadine, Williams, David L, Mueller, Antje“…RESULTS: Despite an activation of nuclear factor (NF)κB, NFinterleukin(IL)-6 and NFAT similar to LPS or TSST-1, we observed no significant production of IL-1β, IL-6, tumor necrosis factor α or interferon γ induced by glucan phosphate. Glucan phosphate-treated leukocytes induced a substantial amount of IL-8 (peak at 18 h: 5000 pg/ml), likely due to binding of NFκB to a consensus site in the IL-8 promoter. …”
Publicado 2006
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30076por Chorley, Brian N, Crews, Anne L, Li, Yuehua, Adler, Kenneth B, Minnicozzi, Michael, Martin, Linda D“…These antibodies were then used to analyze expression of Muc2 and another mucin subtype (likely Muc5ac) in guinea pig tracheal epithelial (GPTE) cells stimulated with a mixture of pro-inflammatory cytokines [tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1β), and interferon- γ (IFN-γ)]. RESULTS: The anti-Muc2 (C4) and anti-MUC5AC (45M1) monoclonal antibodies specifically recognized proteins located in Muc2-dominant small intestinal and Muc5ac-dominant stomach mucosae, respectively, in both Western and ELISA experimental protocols. …”
Publicado 2006
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30077por Jongbloed, Sarah L, Lebre, M Cristina, Fraser, Alasdair R, Gracie, J Alastair, Sturrock, Roger D, Tak, Paul P, McInnes, Iain B“…Functional analysis revealed that both SF DC subsets matured following toll-like receptor stimulation. pDCs from PB and SF produced interferon alpha and tumour necrosis factor alpha on TLR9 stimulation, but only SF pDCs produced IL-10. …”
Publicado 2006
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30078por Radwanska, Magdalena, Cutler, Antony J, Hoving, J. Claire, Magez, Stefan, Holscher, Christoph, Bohms, Andreas, Arendse, Berenice, Kirsch, Richard, Hunig, Thomas, Alexander, James, Kaye, Paul, Brombacher, Frank“…Resistance to L. major in Lck(cre)IL-4Rα(−/lox) mice correlated with reduced numbers of IL-10–secreting cells and early IL-12p35 mRNA induction, leading to increased delayed type hypersensitivity responses, interferon-γ production, and elevated ratios of inducible nitric oxide synthase mRNA/parasite, similar to C57BL/6 mice. …”
Publicado 2007
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30079“…To substitute the autocrine activity by a single physiological component, 28 cytokines, growth factors and biomodulators were tested [interleukin 1alpha (IL-1alpha), IL-1beta, IL-2, IL-3, IL-4, IL-6, IL-10, IL-11, stem cell factor (SCF), platelet-derived growth factor (PDGF), acid fibroblast growth factor (aFGF), basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF-1), IGF-2, insulin, macrophage colony-stimulating factor (M-CSF), granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), oncostatin, RANTES (regulated on activation normal T cell expressed and secreted), angiogenin, leukaemia inhibitory factor (LIF), erythropoietin (EPO), interferon alpha (INF-alpha), INF-gamma, transferrin, tumour necrosis factor alpha (TNF-alpha, TNF-beta and bovine serum albumin for control reasons]. …”
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30080por Hajri, A., Metzger, E., Vallat, F., Coffy, S., Flatter, E., Evrard, S., Marescaux, J., Aprahamian, M.“…Macrophages were activated by HA-hpc2 cells as well as by LPS plus cytokines [interleukin (IL)-1beta plus tumour necrosis factor (TNF)-alpha and interferon (IFN)-gamma]. In HA-hpc2/macrophage co-cultures, NOS activity and inducible NOS (iNOS) transcription were stimulated, whereas an antiproliferative response was observed. …”
Publicado 1998
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