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30101por Lee, Nancy, Woodrum, Chelsey L, Nobil, Alison M, Rauktys, Aubrey E, Messina, Michael P, Dabora, Sandra L“…Cohorts were treated with rapamycin alone or in combination with interferon-gamma (IFN-g). The schedule of rapamycin included one month of daily doses before and after five months of weekly doses. …”
Publicado 2009
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30102por Tsui, Sam-Mui, Lam, Wai-Man, Lam, Tin-Lun, Chong, Hiu-Chi, So, Pui-Kin, Kwok, Sui-Yi, Arnold, Simon, Cheng, Paul Ning-Man, Wheatley, Denys N, Lo, Wai-Hung, Leung, Yun-Chung“…BACKGROUND: Protein used in medicine, e.g. interferon, are immunogenic and quickly broken down by the body. …”
Publicado 2009
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30103por Stefani, Mariane M, Guerra, Jackeline G, Sousa, Ana Lucia M, Costa, Mauricio B, Oliveira, Maria Leide W, Martelli, Celina T, Scollard, David M“…Multiplex bead based technique provided profiles of 27 plasma factors including 16 pro inflammatory cytokines: tumor necrosis factor-α (TNF-α), Interferon-γ (IFN-γ), interleukin (IL)- IL12p70, IL2, IL17, IL1 β, IL6, IL15, IL5, IL8, macrophage inflammatory protein (MIP)-1 alpha (MIP1α), 1 beta (MIP1β), regulated upon activation normal T-cell expressed and secreted (RANTES), monocyte chemoattractrant protein 1 (MCP1), CC-chemokine 11 (CCL11/Eotaxin), CXC-chemokine 10 (CXCL10/IP10); 4 anti inflammatory interleukins: IL4, IL10, IL13, IL1Rα and 7 growth factors: IL7, IL9, granulocyte-colony stimulating factor (G-CSF), granulocyte macrophage-colony stimulating factor (GM-CSF), platelet-derived growth factor BB (PDGF BB), basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF). …”
Publicado 2009
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30104por Böhler, Thomas, Mrosek, Vanessa, Müller, Kerstin, Schnitzler, Paul, Hartmann, Martin, Ouedraogo, Thierry, Coulibaly, Boubacar, Sié, Ali, Bartonova, Vanda, Tebit, Denis M, Kräusslich, Hans-Georg“…Amino acid sequences of CAp24 were assessed in blood samples from 10 HIV-1-infected patients in Nouna, Burkina Faso. Production of interferon-gamma (IFN-γ) in peripheral blood CD4(+) lymphocytes in response to recombinant HIV-1 proteins derived from clade B (including CAp24(NL4-3)) was measured using a modified flow-cytometry-based whole blood short term activation assay (FASTimmune, BDBiosciences). …”
Publicado 2009
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30105por Liu, Tongzheng, Schneider, Ryan A, Shah, Vaibhav, Huang, Yongcheng, Likhotvorik, Rostislav I, Keshvara, Lakhu, Hoyt, Dale G“…BACKGROUND: The peptidyl-proline isomerase, Protein Never in Mitosis Gene A Interacting-1 (PIN1), regulates turnover of inducible nitric oxide synthase (iNOS) in murine aortic endothelial cells (MAEC) stimulated with E. coli endotoxin (LPS) and interferon-γ (IFN). Degradation of iNOS was reduced by a calpain inhibitor, suggesting that PIN1 may affect induction of other calpain-sensitive inflammatory proteins, such as cyclooxygenase (COX)-2, in MAEC. …”
Publicado 2009
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30106por Fletcher, Mary Ann, Zeng, Xiao Rong, Barnes, Zachary, Levis, Silvina, Klimas, Nancy G“…Multiplex technology provided profiles of 16 plasma factors including the pro -inflammatory cytokines: tumor necrosis factor α (TNFα), lymphotoxin α (LTα), interleukin (IL) - IL-Iα, IL-1β, IL-6; T(H)1 cytokines: interferon γ (IFNγ), IL-12p70, IL-2, IL-15; T(H)2: IL-4, IL-5; T(H)17 cytokines, IL-17 and IL-23; anti-inflammatory cytokines IL-10, IL-13; the inflammatory mediator and neutrophil attracting chemokine IL-8 (CXCL8). …”
Publicado 2009
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30107New tools for detecting latent tuberculosis infection: evaluation of RD1-specific long-term responsepor Butera, Ornella, Chiacchio, Teresa, Carrara, Stefania, Casetti, Rita, Vanini, Valentina, Meraviglia, Serena, Guggino, Giuliana, Dieli, Francesco, Vecchi, Marco, Lauria, Francesco N, Marruchella, Almerico, Laurenti, Patrizia, Singh, Mahavir, Caccamo, Nadia, Girardi, Enrico, Goletti, Delia“…BACKGROUND: Interferon-gamma (IFN-γ) release assays (IGRAs) were designed to detect latent tuberculosis infection (LTBI). …”
Publicado 2009
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30108por Yang, Hua-xia, Zhang, Wen, Zhao, Li-dan, Li, Yang, Zhang, Feng-chun, Tang, Fu-lin, He, Wei, Zhang, Xuan“…Moreover, unlike CD4(+)CD25(+)Foxp3(+ )T cells, CD4(+)CD25(-)Foxp3(+ )T cells also synthesized interferon-gamma, interleukin (IL)-4, IL-2, and IL-17 (P < 0.05), though less than CD4(+)CD25(+)Foxp3(- )T cells. …”
Publicado 2009
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30109por del Corral, Helena, París, Sara C., Marín, Nancy D., Marín, Diana M., López, Lucelly, Henao, Hanna M., Martínez, Teresita, Villa, Liliana, Barrera, Luis F., Ortiz, Blanca L., Ramírez, María E., Montes, Carlos J., Oquendo, María C., Arango, Lisandra M., Riaño, Felipe, Aguirre, Carlos, Bustamante, Alberto, Belisle, John T., Dobos, Karen, Mejía, Gloria I., Giraldo, Margarita R., Brennan, Patrick J., Robledo, Jaime, Arbeláez, María P., Rojas, Carlos A., García, Luis F.“…Identification of individuals at risk of tuberculosis disease is a desirable goal for tuberculosis control. Interferon-gamma release assays (IGRAs) using specific M. tuberculosis antigens provide an alternative to tuberculin skin testing (TST) for infection detection. …”
Publicado 2009
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30110por Penna-Martinez, Marissa, Ramos-Lopez, Elizabeth, Robbers, Inka, Kahles, Heinrich, Hahner, Stefanie, Willenberg, Holger, Reisch, Nicole, Seidl, Christian, Segni, Maria, Badenhoop, Klaus“…Recent studies showed that a genetic variation within the interferon induced helicase domain 1 (IFIH1) locus (rs1990760 polymorphism) is an additional risk factor in type 1 diabetes and Graves' disease (GD). …”
Publicado 2009
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30111por Wang, Sophia S., Gonzalez, Paula, Yu, Kai, Porras, Carolina, Li, Qizhai, Safaeian, Mahboobeh, Rodriguez, Ana Cecilia, Sherman, Mark E., Bratti, Concepcion, Schiffman, Mark, Wacholder, Sholom, Burk, Robert D., Herrero, Rolando, Chanock, Stephen J., Hildesheim, Allan“…Genes/regions statistically significantly associated with CIN3/cancer included the viral infection and cell entry genes 2′,5′ oligoadenylate synthetase gene 3 (OAS3), sulfatase 1 (SULF1), and interferon gamma (IFNG); the DNA repair genes deoxyuridine triphosphate (DUT), dosage suppressor of mck 1 homolog (DMC1), and general transcription factor IIH, polypeptide 3 (GTF2H4); and the EVER1 and EVER2 genes (p<0.01). …”
Publicado 2010
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30112por Eton, Omar, Ross, Merrick I, East, Mary Jo, Mansfield, Paul F, Papadopoulos, Nicholas, Ellerhorst, Julie A, Bedikian, Agop Y, Lee, Jeffrey E“…In vivo induction of immunity was evaluated using delayed-type hypersensitivity (DTH) to HSPPC-96, irradiated tumor, and dinitrochlorobenzene (DNCB). The γ-interferon (IFNγ) ELISPOT assay was used to measure induction of a peripheral blood mononuclear cell response against autologous tumor cells at baseline and at the beginning of weeks 3, 4, and 8. …”
Publicado 2010
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30113por Pooran, Anil, Booth, Helen, Miller, Robert F, Scott, Geoff, Badri, Motasim, Huggett, Jim F, Rook, Graham, Zumla, Alimuddin, Dheda, Keertan“…BACKGROUND: Previous health economic studies recommend either a dual screening strategy [tuberculin skin test (TST) followed by interferon-γ-release assay (IGRA)] or a single one [IGRA only] for latent tuberculosis infection (LTBI), the former largely based on claims that it is more cost-effective. …”
Publicado 2010
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30114por Mardani, Masoud, Tabarsi, Payam, Mohammadtaheri, Zohre, Chitsaz, Ehsan, Farokhzad, Banafsheh, Hadavand, Fatemeh, Gachkar, Latif, Nemati, Kambiz, Masjedi, Mohammad R.“…A TST with purified protein derivative (PPD) and whole-blood interferon-gamma release assay (IGRA) in reaction to ESAT-6 and CFP-10 antigens was performed and measured by enzyme-linked immuno-sorbent assay (ELISA). …”
Publicado 2010
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30115por Shah, Kamini, Lee, Won-Woo, Lee, Seung-Hyun, Kim, Sang Hyun, Kang, Seong Wook, Craft, Joe, Kang, Insoo“…The development of Th17 cells is suppressed by interferon (IFN)-γ produced by Th1 cells, suggesting cross-regulation between Th17 and Th1 cells. …”
Publicado 2010
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30116por Feng, Xuebing, Li, Rongliang, Huang, Jing, Zhang, Huayong, Zhu, Lina, Hua, Bingzhu, Tsao, Betty P, Sun, Lingyun“…Co-culturing with OAZ siRNAs reduced mRNA levels of OAZ by 74.6 ± 6.4% as compared to those co-cultured with non-targeting siRNA and OAZ silencing resulted in reduced total IgG, ANA, interferon (IFN)-γ, interleukin (IL)-10, IL-12 and IL-21, but elevated CCL2 levels in culture supernatants (P < 0.05). …”
Publicado 2010
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30117por Joimel, Ulrich, Gest, Caroline, Soria, Jeannette, Pritchard, Linda-Louise, Alexandre, Jérôme, Laurent, Marc, Blot, Emmanuel, Cazin, Lionel, Vannier, Jean-Pierre, Varin, Rémi, Li, Hong, Soria, Claudine“…Mφ phenotype was evaluated by 1) expression of the M1 marker CD80, and secretion of interleukin 10 (IL-10), an M2 marker; 2) capacity to secrete Tumour Necrosis Factor α (TNFα) when stimulated by lipopolysaccharide/interferon γ (LPS/IFNγ); 3) ability to induce MDA-MB-231 apoptosis. …”
Publicado 2010
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30118por Worthington, Jenny, Bertani, Mariana, Chan, Hong-Lin, Gerrits, Bertran, Timms, John F“…We also report ErbB2-dependent down-regulation of multiple interferon-stimulated genes that may permit ErbB2-overexpressing cells to resist the anti-proliferative action of interferons. …”
Publicado 2010
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30119“…METHODS: Eight SCGB family members including SCGB3A2 (UGRP1), SCGB1C1 (ligand binding protein RYD5), SCGB1D1 (lipophilin A), SCGB1D2 (lipophilin B), SCGB1D4 (interferon-γ inducible SCGB), SCGB2A1 (mammaglobin 2), SCGB2A2 (mammaglobin 1), and SCGB3A1 (uteroglobin-related protein 2) were studied. …”
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30120por Lin, Chun-Yen, Chen, Ji-Yih, Lin, Tsung-Nan, Jeng, Wen-Juei, Huang, Chien-Hao, Huang, Chang-Wen, Chang, Su-Wei, Sheen, I-Shyan“…BACKGROUND: Single nucleotide polymorphisms (SNPs) of interleukin-28B (IL28B) have received considerable interest for their association with sustained virological response (SVR) when treating patients of genotype-1 hepatitis C virus (GT1-HCV) chronic infection with pegylated interferon and ribavirin (PegIFN/RBV). This study was to investigate the predictive power of IL28B SNPs for on-treatment responses and SVR in treatment-naïve patients with GT1-HCV chronic infection. …”
Publicado 2011
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