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30201por Baquero-Perez, Belinda, Kuchipudi, Suresh V., Ho, Jemima, Sebastian, Sujith, Puranik, Anita, Howard, Wendy, Brookes, Sharon M., Brown, Ian H., Chang, Kin-Chow“…Additionally, in chicken myotubes infected with H5N1 viruses, the induction of interferon beta (IFN-β) and IFN-inducible genes, including the melanoma differentiation-associated protein 5 (MDA-5) gene, was relatively weak compared to infection with the corresponding H2N3 virus. …”
Publicado 2014
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30202por Yin, Qingsong, Chen, Lin, Li, Qianyu, Mi, Ruihua, Li, Yufu, Wei, Xudong, Song, Yongping“…METHODS: A total of 56 DLBCL patients were recruited for analysis of T-cell subset distribution in the peripheral blood using flow cytometry; serum interferon (IFN)-γ and interleukin (IL)-4 levels using enzyme-linked immunosorbent assays; and early growth response protein 1 (EGR-1), T-bet, GATA-binding protein 3 (GATA-3), and transforming growth factor (TGF)-β mRNA levels using quantitative reverse-transcription polymerase chain reaction. …”
Publicado 2014
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30203por Schläpfer, Martin, Piegeler, Tobias, Dull, Randal O, Schwartz, David E, Mao, Mao, Bonini, Marcelo G, Z’Graggen, Birgit Roth, Beck-Schimmer, Beatrice, Minshall, Richard D“…Also blood levels of inflammatory mediators (tumor necrosis factor-α, interleukin-1β, interleukin-10, CXCL-2, interferon-γ and high mobility group protein-1) were accentuated in propofol + CLP rats compared to the isoflurane + CLP group at the same time point (P <0.04). …”
Publicado 2015
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30204por Luo, ZhaoHui, Li, Ye, Liu, XiaoFang, Luo, MengChuan, Xu, LiQun, Luo, YueBei, Xiao, Bo, Yang, Huan“…Several GO terms including the cellular response to interferon-γ, platelet degranulation, chemokine receptor binding and cytokine interactions were very important in MG pathogenesis. …”
Publicado 2015
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30205por Sun, Hsin-Yun, Hsueh, Po-Ren, Liu, Wen-Chun, Su, Yi-Ching, Chang, Sui-Yuan, Hung, Chien-Ching, Chang, Shan-Chwen“…BACKGROUND: Interferon-gamma release assays (IGRAs) have been used to identify individuals at risk for developing active tuberculosis (TB). …”
Publicado 2015
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30206por Di Bonito, Paola, Petrone, Linda, Casini, Gabriele, Francolini, Iolanda, Ammendolia, Maria Grazia, Accardi, Luisa, Piozzi, Antonella, D’Ilario, Lucio, Martinelli, Andrea“…Immunoglobulin G isotyping and interferon gamma analysis suggested a mixed Th1/Th2 immune response in both E7-PLLA(sc)-immunized and E7-APLLA(sc)-immunized mice. …”
Publicado 2015
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30207por Janowicz, Anna, Caporale, Marco, Shaw, Andrew, Gulletta, Salvatore, Di Gialleonardo, Luigina, Ratinier, Maxime, Palmarini, Massimo“…Replication of BTV8(H) was relatively poor in interferon (IFN)-competent primary ovine endothelial cells compared to replication of BTV8(L), and this phenotype was determined by several viral genomic segments, including Seg4 and Seg9. …”
Publicado 2015
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30208por Chin, Christine Lin, Chin, Hing Kah, Chin, Cara Sze Hui, Lai, Ethan Tingfeng, Ng, Say Kong“…Destabilization of dihydrofolate reductase (dhfr) selection marker by addition of AU-rich elements and murine ornithine decarboxylase PEST region was previously shown to improve the specific productivities of recombinant human interferon gamma in CHO-DG44 cells. In this study, we evaluated novel combinations of engineered motifs for further selection marker attenuation to improve recombinant human alpha-1-antitrypsin (rhA1AT) production. …”
Publicado 2015
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30209“…The Enzyme-Linked Immunosorbent Assay (ELISA) analysis was applied to evaluate the production of Interleukin 6 (IL-6), Tumor necrosis factor α (TNF-α) and Interferon β (IFN-β). Moreover, viral dynamics were analyzed using HBV DNA and HBV-related antigens (HBsAg and HBeAg). …”
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30210por Zeng, Ming, Li, Zhi-Yong, Ma, Jin, Cao, Ping-Ping, Wang, Heng, Cui, Yong-Hua, Liu, Zheng“…RESULTS: We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory mediators (Clara cell 10-kDa protein and interleukin (IL)-10), whereas down-regulated the production of Th2 response and eosinophilia promoting molecules (thymic stromal lymphopoietin, IL-25, IL-33, CD80, CD86, OX40 ligand, programmed cell death ligand 1, CCL17, CCL22, CCL11, CCL5, IL-5, IL-13, and eosinophilic cationic protein) and Th1 response and neutrophilia promoting molecules (CXCL8, CXCL5, CXCL10, CXCL9, interferon-γ, and IL-12), from sinonasal mucosa from distinct phenotypic CRS. …”
Publicado 2015
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30211por Souza, Mariana C, Silva, Johnatas D, Pádua, Tatiana A, Torres, Natália D, Antunes, Mariana A, Xisto, Debora G, Abreu, Thiago P, Capelozzi, Vera L, Morales, Marcelo M, Sá Pinheiro, Ana A., Caruso-Neves, Celso, Henriques, Maria G, Rocco, Patricia RM“…These morphological and functional changes were not associated with changes in levels of tumor necrosis factor-α, keratinocyte-derived chemokine (KC, a mouse analog of interleukin-8), or interferon-γ, which remained increased and similar to those of P. berghei animals treated with saline. …”
Publicado 2015
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30212por Dammermann, Werner, Bentzien, Frank, Stiel, Eva-Maria, Kühne, Claudia, Ullrich, Sebastian, zur Wiesch, Julian Schulze, Lüth, Stefan“…BACKGROUND: Interferon gamma release assays (IGRA) have been developed to support easy and fast diagnosis of diseases like tuberculosis, and CMV in transplant patients. …”
Publicado 2015
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30213por Cheung, Y. T., Ng, T., Shwe, M., Ho, H. K., Foo, K. M., Cham, M. T., Lee, J. A., Fan, G., Tan, Y. P., Yong, W. S., Madhukumar, P., Loo, S. K., Ang, S. F., Wong, M., Chay, W. Y., Ooi, W. S., Dent, R. A., Yap, Y. S., Ng, R., Chan, A.“…Proinflammatory plasma cytokines concentrations [interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, granulocyte–macrophage colony-stimulating factor, interferon-γ and tumor necrosis factor-α] were evaluated at 3 time points (before chemotherapy, 6 and 12 weeks after chemotherapy initiation). …”
Publicado 2015
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30214“…METHODS: Resistin along with a panel of Th1/Th2 cytokines [interferon (IFN)-gamma, interleukin (IL)-1beta, IL-2, IL-6, IL-8, IL10, IL-12, IL-13 and tumor necrosis factor (TNF)] was analyzed in 36 DBDs after the diagnosis of BD and before organ procurement and in 12 living kidney donors (LD). …”
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30215por Zhao, Xiang-Yu, Wang, Yu-Tong, Mo, Xiao-Dong, Zhao, Xiao-Su, Wang, Ya-Zhe, Chang, Ying-Jun, Huang, Xiao-Jun“…T-cell subgroups, including conventional T cells and different types of Treg cells, as well as the percentage of Ki67 expression on CD4(+)CD25(high)Foxp3(+) Treg cells, were analyzed using flow cytometry. The levels of interferon-γ (IFN-γ) and interleukin-17 (IL-17) secreted by T cells stimulated with PMA and ionomycin were also determined by flow cytometry. …”
Publicado 2015
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30216por Offerman, Kristy, Deffur, Armin, Carulei, Olivia, Wilkinson, Robert, Douglass, Nicola, Williamson, Anna-Lise“…These six viruses produced qualitatively and quantitatively distinct host responses with LSDV, followed by MVA, inducing the greatest interferon (IFN) response. FeP2 and PEPV caused very little change to host transcript abundance compared to the other 4 viruses tested. …”
Publicado 2015
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30217por LIU, MING-WEI, SU, MEI-XIAN, ZHANG, WEI, ZHANG, LIN-MING, WANG, YUN-HUI, QIAN, CHUAN-YUN“…Levels of T-helper cell type 1 (Th1) cytokines [Interleukin (IL)-2, IL-12 and interferon (IFN)-γ] and Th2 cytokines (IL-4 and IL-10) were determined using ELISA. …”
Publicado 2015
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30218por Jung, Jaesung, Kim, Nam Keun, Park, Sun, Shin, Ho-Joon, Hwang, Seong Gyu, Kim, Kyongmin“…Phyllanthus extract induced interferon-beta (IFN-β), cyclooxygenase-2 (COX-2), and interleukin-6 (IL-6) mRNA expression in HBV WT-transfected HepG2 cells, possibly via activation of extracellular signal-regulated kinases and c-jun N-terminal kinases and the induction of retinoic acid inducible gene-I, toll-like receptor 3, myeloid differentiation primary response gene 88, and/or tumor necrosis factor receptor-associated factor 6 gene expression. …”
Publicado 2015
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30219por Steinebrunner, Niels, Sprinzl, Martin F., Zimmermann, Tim, Wörns, Marcus A., Zimmerer, Thomas, Galle, Peter R., Stremmel, Wolfgang, Eisenbach, Christoph, Stein, Kerstin, Antoni, Christoph, Schattenberg, Jörn M., Pathil, Anita“…BACKGROUND: The combination of sofosbuvir (SOF), ribavirin (RBV) and peg-interferon-alfa-2a (peg-IFN-alfa-2a) as well as the combination of SOF and RBV for the treatment of patients infected with hepatitis c virus (HCV) has improved rates of sustained virological response (SVR) considerably in recent trials. …”
Publicado 2015
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30220por Spadaro, Michela, Caldano, Marzia, Marnetto, Fabiana, Lugaresi, Alessandra, Bertolotto, Antonio“…METHODS: We performed a flow cytometric analysis on peripheral blood mononuclear cells (PBMC); we collected from 23 healthy donors and 225 MS patients: untreated (n = 19) or treated with NTZ (n = 113), interferon-beta (n = 26), glatiramer acetate (n = 26), fingolimod (n = 23) and rituximab (n = 18). …”
Publicado 2015
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