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  1. 30221
    “…We aimed to develop and validate a clinical algorithm, using baseline CD4 cell counts, HIV viral load (pVL), and interferon-gamma release assay (IGRA), to identify PLHIV who are at high risk for incident active TB in low-to-moderate TB burden settings where highly active antiretroviral therapy (HAART) is routinely provided. …”
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  2. 30222
    “…Patients’ kynurenine pathway metabolites correlated with the levels of inflammatory markers, including that of the major IDO-inducer, interferon-gamma. Indications are that the rate of de novo synthesis of nicotinamide in the kynurenine pathway correlates with increases in quinolinic acid levels up to a point where saturation of the enzyme quinolinate phosphoribosyl transferase occurs. …”
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  3. 30223
    “…HS was associated with significantly more intraoperative bleeding (mean difference [MD] 57.15, 95% confidence interval [CI] 18.83–95.46, P=0.003), and CD4/CD8 ratio (MD 0.69, 95% CI 0.61–0.77, P<0.00001), CD4 subset, platelet count (MD 213.06, 95% CI 202.59–223.53, P<0.0001), white blood cell count (MD 4.85, 95% CI 4.58–5.13, P<0.0001), interferon-gamma levels (MD 18.52, 95% CI 13.93–23.11, P<0.00001), and interleukin-2 levels (MD 20.73, 95% CI 16.05–25.41, P<0.0001). …”
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  4. 30224
    “…Tissue samples were analyzed for total IgE levels and for mRNA expression levels of interleukin (IL)-4, IL–5, IL–13, interferon (IFN)-γ, tumor necrosis factor (TNF)-α, IL-17A, IL–22, IL-23p19, transforming growth factor (TGF)-β1, TGF-β2, TGF-β3, and periostin. …”
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  5. 30225
    “…Previous studies have revealed antibody to hepatitis B core antigen (anti-HBc) levels as a predictor of treatment response in hepatitis B early antigen (HBeAg)-positive chronic hepatitis B (CHB) patients in both interferon and nucleos(t)ide analog therapy cohorts. …”
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  6. 30226
  7. 30227
    “…METHODS: Civilian, noninstitutionalized U.S. population survey participants aged 6 years and older were interviewed regarding their TB history and eligibility for the tuberculin skin test (TST) and interferon gamma release assay (IGRA) blood test. Once eligibility was confirmed, both tests were conducted. …”
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  8. 30228
    “…BACKGROUND: Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. …”
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  9. 30229
    “…Exposure to ambient PM(2.5) (particulate matter equal or smaller than 2.5 μm) was 24 hour individually collected and the collection of tears was performed to measure interleukins (IL) 2, 4, 5 and 10 and interferon gamma (IFN-γ) levels. Data from both groups were compared using Student’s t test or Mann- Whitney test for cytokines. …”
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  10. 30230
    por Getahun, Haileyesus, Matteelli, Alberto, Abubakar, Ibrahim, Aziz, Mohamed Abdel, Baddeley, Annabel, Barreira, Draurio, Den Boon, Saskia, Borroto Gutierrez, Susana Marta, Bruchfeld, Judith, Burhan, Erlina, Cavalcante, Solange, Cedillos, Rolando, Chaisson, Richard, Chee, Cynthia Bin-Eng, Chesire, Lucy, Corbett, Elizabeth, Dara, Masoud, Denholm, Justin, de Vries, Gerard, Falzon, Dennis, Ford, Nathan, Gale-Rowe, Margaret, Gilpin, Chris, Girardi, Enrico, Go, Un-Yeong, Govindasamy, Darshini, D. Grant, Alison, Grzemska, Malgorzata, Harris, Ross, Horsburgh Jr, C. Robert, Ismayilov, Asker, Jaramillo, Ernesto, Kik, Sandra, Kranzer, Katharina, Lienhardt, Christian, LoBue, Philip, Lönnroth, Knut, Marks, Guy, Menzies, Dick, Migliori, Giovanni Battista, Mosca, Davide, Mukadi, Ya Diul, Mwinga, Alwyn, Nelson, Lisa, Nishikiori, Nobuyuki, Oordt-Speets, Anouk, Rangaka, Molebogeng Xheedha, Reis, Andreas, Rotz, Lisa, Sandgren, Andreas, Sañé Schepisi, Monica, Schünemann, Holger J., Sharma, Surender Kumar, Sotgiu, Giovanni, Stagg, Helen R., Sterling, Timothy R., Tayeb, Tamara, Uplekar, Mukund, van der Werf, Marieke J., Vandevelde, Wim, van Kessel, Femke, van't Hoog, Anna, Varma, Jay K., Vezhnina, Natalia, Voniatis, Constantia, Vonk Noordegraaf-Schouten, Marije, Weil, Diana, Weyer, Karin, Wilkinson, Robert John, Yoshiyama, Takashi, Zellweger, Jean Pierre, Raviglione, Mario
    Publicado 2015
    “…In prisoners, healthcare workers, immigrants from high TB burden countries, homeless persons and illicit drug users, systematic testing and treatment of LTBI is conditionally recommended, according to TB epidemiology and resource availability. Either commercial interferon-gamma release assays or Mantoux tuberculin skin testing could be used to test for LTBI. …”
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  11. 30231
    “…The core response is type I Interferon (IFN)-driven, involving the NF-κB and MAPK signaling pathways with concomitant pro-inflammatory cytokine production, and network analysis identified STAT1, EGR1, and SRC as key hub and bottleneck genes. …”
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  12. 30232
    “…Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. …”
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  13. 30233
  14. 30234
  15. 30235
    “…In contrast HAZV is not associated with serious human disease, although infection of interferon receptor knockout mice with either CCHFV or HAZV results in similar disease progression. …”
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  16. 30236
  17. 30237
    “…Previous research has indicated that IL-17 plays a proinflammatory role by exacerbating interferon-γ (IFN-γ)-induced inflammation. However, prior to this study, it was not known whether inducible nitric oxide synthase (iNOS or NOS2), a signature molecule of inflammation, could be intensified by IL-17 when combined with IFN-γ. …”
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  18. 30238
    “…Serum samples were collected before treatment and were assayed by multiplex assays for levels of interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, interferon-γ, tumor necrosis factor-α, MMP-1, MMP-3, and MMP-9. …”
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  19. 30239
    “…Genome-wide association studies have shown that single nucleotide polymorphisms (SNPs) near IL 28B gene on chromosome 19 are strong predictors of sustained virologic response (SVR) to pegylated interferon and ribavirin. This study was aimed at analyzing the co-prevalence of two common and clinically significant SNPs in a cohort of Ligurian patients. …”
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  20. 30240
    “…In all subjects, peripheral Vδ1 and Vδ2 T cells were analyzed for cell frequencies, the activation marker CD69, the cytotoxicity markers NKG2D and NKG2A, and the intracellular cytokines tumor necrosis factor (TNF)α, interferon (IFN)γ, interleukin (IL)-17 and IL-10. RESULTS: Pregnant patients showed a decreased Vδ2/Vδ1 ratio in the third trimester, which resulted from a slightly reduced proportion of Vδ2 cells. …”
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