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30321por Fujita, K, Nakai, Y, Kawashima, A, Ujike, T, Nagahara, A, Nakajima, T, Inoue, T, Lee, C M, Uemura, M, Miyagawa, Y, Kaneda, Y, Nonomura, N“…NK cell activity was elevated from day 12 to day 28 after HVJ-E administration, whereas serum interleukin-6, interferon (IFN)-α, IFN-β and IFN-γ levels were not affected by HVJ-E treatment. …”
Publicado 2017
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30322“…RESULTS: Interleukin (IL)-10-592 AC and IL-4-589 CC/CT showed a synergistic effect on liver inflammatory injury (p<0.01), whereas interferon (IFN)-γ+874 AA and IL-2-330 TT had a synergistic impact (p<0.05). …”
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30323por Ohnishi, Junji, Ayuzawa, Satoshi, Nakamura, Seiji, Sakamoto, Shigeko, Hori, Miyo, Sasaoka, Tomoko, Takimoto-Ohnishi, Eriko, Tanatsugu, Masakazu, Murakami, Kazuo“…RESULTS: The microarray analyses revealed that the distinct transcripts in the Buddhist priests included up-regulated genes related to type I interferon (IFN) innate anti-viral responses (i.e., MX1, RSAD2, IFIT1, IFIT3, IFI27, IFI44L, and HERC5), and the genes C17orf97 (ligand of arginyltranseferase 1; ATE1), hemoglobin γA (HBG1), keratin-associated protein (KRTAP10-12), and sialic acid Ig-like lectin 14 (SIGLEC14) were down-regulated at baseline. …”
Publicado 2017
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30324por Xue, Chunxue, Wen, Mingjie, Bao, Linlin, Li, Hui, Li, Fengdi, Liu, Meng, Lv, Qi, An, Yunqing, Zhang, Xulong, Cao, Bin“…In addition to secreting IL-17A, γδT cells secreted interferon (IFN)-γ and expressed both an activation-associated molecule, natural killer group 2, member D (NKG2D), and an apoptosis-associated molecule, FasL. …”
Publicado 2017
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30325por Zhou, Saijun, Lu, Ming, Zhao, Jiantong, Liu, Shuaihui, Li, Xin, Zhang, Rui, Liu, Hongyan, Yu, Pei“…The levels of tumour necrosis factor-alpha (TNF-α),interleukin-6 (IL-6) interleukin-10 (IL-10),interleukin-12P70 (IL-12P70),interferon-gamma (IFN-γ) and monocyte chemoattractant protein −1(MCP-1) in mouse serum were quantified to assess its anti-inflammatory activity in lipopolysaccharide (LPS)-mediated systemic inflammation. …”
Publicado 2017
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30326por Leite, Aline Zazeri, Rodrigues, Nathália de Campos, Gonzaga, Marina Ignácio, Paiolo, João Carlos Cicogna, de Souza, Carolina Arantes, Stefanutto, Nadine Aparecida Vicentini, Omori, Wellington Pine, Pinheiro, Daniel Guariz, Brisotti, João Luiz, Matheucci Junior, Euclides, Mariano, Vânia Sammartino, de Oliveira, Gislane Lelis Vilela“…We find correlations between the proinflammatory interferon-gamma with Gram-negatives Bacteroides and Prevotella species, and a positive correlation between the LPS levels and P. copri reads. …”
Publicado 2017
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30327por Chen, Yung-Che, Lin, An-Shen, Hung, Yu-Chiang, Chen, Kuang-Den, Wu, Ching-Yuan, Lie, Chien-Hao, Hsiao, Chang-Chun, Chen, Chung-Jen, Liu, Shih-Feng, Fang, Wen-Feng, Chang, Jen-Chieh, Wang, Ting-Ya, Wang, Yi-Hsi, Chung, Yu-Hsiu, Chao, Tung-Ying, Leung, Sum-Yee, Su, Mao-Chang, Lin, Meng-Chih“…A total of 48 genes associated with neutrophil migration, coagulation, thrombosis and type I interferon signaling were down-regulated following rikkunshito treatment. …”
Publicado 2017
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30328por Bluen, Benjamin, Kesaris, Anna, Coppock, Dagan, Boyle, Suzanne, Chou, Edgar, Lee, Dong Heun“…BACKGROUND: Non-interferon based treatment regimens have transformed the therapeutic paradigm for hepatitis C infection. …”
Publicado 2017
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30329“…At Bach Mai, 3% of HIV patients coinfected with HCV only and 2% of HIV patients with both HCV/HBV received treatment for their HCV. Pegylated interferon+ribavirin was the only regimen used. CONCLUSION: Compared with the general Vietnamese population, HCV was more prevalent among our sample of HIV+ individuals. …”
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30330por Chaudhury, Chloe, Sheehan, Julia, Chairez, Cheryl, Akoth, Elizabeth, Gross, Chloe, Kattakuzhy, Sarah, Rosenthal, Elana, Kottilil, Shyam, Masur, Henry, Hadigan, Colleen“…BACKGROUND: Historically, eradication of HCV with interferon-based treatments was linked with decreased incidence of diabetes. …”
Publicado 2017
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30331“…Most of the patients (17) were treated with older therapies (peg-interferon alpha with or without boceprevir or telaprevir) and 7 with newer DAA combinations, whereas 16 patients did not receive treatment. …”
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303324-Nitroquinoline 1-Oxide-Induced Tongue and Esophagus Carcinogenesis in Obese and Diabetic TSOD Mice“…Also, mRNA expression of eight cytokines including interleukin (IL)-1β, IL-6, IL-17, interferon (IFN)-γ, keratinocyte-derived cytokine (KC), macrophage inflammatory protein (MIP)-1α, MIP-2, and tumor necrosis factor (TNF)-α in the esophageal mucosa was assayed. …”
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30333por Li, Wenliang, Mao, Li, Cao, Yongguo, Zhou, Bin, Yang, Leilei, Han, Linxiao, Hao, Fei, Lin, Tao, Zhang, Wenwen, Jiang, Jieyuan“…Viperin is one of the hundreds of interferon-stimulated genes (ISGs), and possesses a wide range of antiviral activities. …”
Publicado 2017
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30334por Gopinathan, Unni, Øvstebø, Reidun, Brusletto, Berit Sletbakk, Olstad, Ole Kristoffer, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter“…RESULTS: In both experimental models, GSEA and IPA identified genes associated with pro-inflammatory innate immune activation, including TNF-signaling, Toll-like receptor signaling, JAK-STAT-signaling, and type I and type II interferon signaling. GSEA identified genes regulated by the presence of IL-10 with similar gene sets in both the model system and the patient plasma system. …”
Publicado 2017
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30335por Das, Arundhoti, Ranganathan, Vidya, Umar, Danish, Thukral, Shipra, George, Anna, Rath, Satyajit, Bal, Vineeta“…Based on cytokine based polarization of NCD4T cells in vitro, programming for either ‘Th1’ (interferon-gamma [IFNg]) or ‘Th2’ (interleukin [IL]-4/5/13) cytokines is thought to occur via mutually exclusive expression and functioning of T-bet or GATA-3 transcription factors (TFs). …”
Publicado 2017
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30336por Kampan, Nirmala Chandralega, Madondo, Mutsa Tatenda, McNally, Orla M., Stephens, Andrew N., Quinn, Michael A., Plebanski, Magdalena“…Functionally, TNFR2(+) Treg frequency was inversely correlated with interferon-gamma (IFN-γ) production by effector T cells, and was uniquely able to suppress TNFR2(+) T effectors. …”
Publicado 2017
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30337por Yong, Michelle K., Cameron, Paul U., Slavin, Monica A., Cheng, Allen C., Morrissey, C. Orla, Bergin, Krystal, Spencer, Andrew, Ritchie, David, Lewin, Sharon R.“…We aimed to determine the relationship between T-cell production of interferon gamma (IFN-γ) in response to phytohemagglutinin (PHA) to clinical outcomes in HSCT recipients. …”
Publicado 2017
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30338por Abreu, Soraia C., Antunes, Mariana A., Xisto, Debora G., Cruz, Fernanda F., Branco, Vivian C., Bandeira, Elga, Zola Kitoko, Jamil, de Araújo, Almair F., Dellatorre‐Texeira, Ludmilla, Olsen, Priscilla C., Weiss, Daniel J., Diaz, Bruno L., Morales, Marcelo M., Rocco, Patricia R. M.“…Only BM‐MSCs increased IL‐10 and interferon (IFN)‐γ in lung tissue. In parallel in vitro experiments, BM‐MSCs increased M2 macrophage polarization, whereas AD‐MSCs and LUNG‐MSCs had higher baseline levels of IL‐4, insulin‐like growth factor (IGF), and VEGF secretion. …”
Publicado 2017
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30339“…Patients infected with HCV GT1, 2, 4, 5 or 6 recover to a greater extent, as measured by sustained virological response (SVR), following treatment with regimens based on direct-acting antivirals (DAAs) than after treatment with older regimens based on pegylated interferon (Peg-IFN). GT3, however, is regarded as being more difficult to treat as it is a relatively aggressive genotype, associated with greater liver damage and cancer risk; some subgroups of patients with GT3 infection are less responsive to current licensed DAA treatments. …”
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30340“…The levels of the inflammatory cytokines interleukin-17 (IL-17), tumour necrosis factor-α (TNF-α), and interferon-γ (IFN-γ) were measured by enzyme-linked immunosorbent assay. …”
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