-
30461por Brunton, Bethany, Rogers, Kai, Phillips, Elisabeth K., Brouillette, Rachel B., Bouls, Ruayda, Butler, Noah S., Maury, Wendy“…TIM-1-sufficient or TIM-1-deficient BALB/c interferon α/β receptor(-/-) mice were challenged with these viruses. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30462por Shitara, Kohei, Ueha, Satoshi, Shichino, Shigeyuki, Aoki, Hiroyasu, Ogiwara, Haru, Nakatsura, Tetsuya, Suzuki, Toshihiro, Shimomura, Manami, Yoshikawa, Toshiaki, Shoda, Kayoko, Kitano, Shigehisa, Yamashita, Makiko, Nakayama, Takayuki, Sato, Akihiro, Kuroda, Sakiko, Wakabayashi, Masashi, Nomura, Shogo, Yokochi, Shoji, Ito, Satoru, Matsushima, Kouji, Doi, Toshihiko“…Moreover, transcriptomic profiling of the liver metastasis of the patient revealed upregulation of the expression of interferon-stimulated genes, T cell activation-related genes, and antigen presentation-related genes after IT1208 administration. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30463por Ryu, Gwanghui, Kim, Dong-Kyu, Dhong, Hun-Jong, Eun, Kyoung Mi, Lee, Kyung Eun, Kong, Il Gyu, Kim, HyoYeol, Chung, Seung-Kyu, Kim, Dong-Young, Rhee, Chae-Seo, Cho, Seong-Ho, Hong, Sang Duk, Kim, Dae Woo“…Cytokine profile analysis showed that levels of Th17-associated mediators (myeloperoxidase, interleukin (IL)-8, IL-17A and IL-23), B-cell activating factor (BAFF) and Th1 cytokine (interferon-γ) were up-regulated in rNP compared to controls and pNP. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30464por McInnes, Iain B., Byers, Nicole L., Higgs, Richard E., Lee, Jonathan, Macias, William L., Na, Songqing, Ortmann, Robert A., Rocha, Guilherme, Rooney, Terence P., Wehrman, Thomas, Zhang, Xin, Zuckerman, Steven H., Taylor, Peter C.“…All JAKis tested inhibited JAK1/2-dependent cytokines (e.g., IL-6 and interferon [IFN]-γ), the JAK1/tyrosine kinase 2 (TYK2)-dependent cytokines IL-10 and IFN-α, the JAK2/2-dependent cytokines IL-3 and granulocyte-macrophage colony-stimulating factor (GM-CSF), and the JAK2/TYK2-dependent cytokine granulocyte colony-stimulating factor (G-CSF), but often to significantly differing degrees. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30465por Doyle, Erin Heather, Rahman, Adeeb, Aloman, Costica, Klepper, Arielle L., El-Shamy, Ahmed, Eng, Francis, Rocha, Chiara, Kim, Sang, Haydel, Brandy, Florman, Sander S., Fiel, M. Isabel, Schiano, Thomas, Branch, Andrea D.“…Plasmacytoid dendritic cells (pDCs) are “natural” interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make cytokines remain unanswered. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30466por Yu, Zhi-Chao, Cen, Yong-Xin, Wu, Ben-Hua, Wei, Cheng, Xiong, Feng, Li, De-Feng, Liu, Ting-Ting, Luo, Ming-Han, Guo, Li-Liangzi, Li, Ying-Xue, Wang, Li-Sheng, Wang, Jian-Yao, Yao, Jun“…Oral administration of BBR inhibited the NF-κB signal transduction pathway, reduced the expression of pro-inflammatory cytokines [interleukin (IL)-1β, IL-6, interferon-γ, and tumor necrosis factor-α], promoted the expression of anti-inflammatory cytokines (IL-10 and transforming growth factor-β), and improved the terminal ileum tissue inflammation. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30467por Kannagi, Mari, Hasegawa, Atsuhiko, Nagano, Yoshiko, Kimpara, Shuichi, Suehiro, Youko“…In addition, type I interferon (IFN) suppresses HTLV-1 expression in a reversible manner. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30468“…In four of these patients, interleukin (IL)-23, IL-27, and interferon-gamma (IFN-γ) measurements were not performed since pleural effusion samples could not be collected because the effusion had been drained prior to the study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30469por Lin, Qi, Ren, Li, Jian, Mi, Xu, Pingping, Li, Jun, Zheng, Peng, Feng, Qingyang, Yang, Liangliang, Ji, Meilin, Wei, Ye, Xu, Jianmin“…Immunohistochemistry was used to detect sphingosine-1-phosphate receptor 1 (S1PR1) and signal transducer and activator of transcription-3 (STAT3) in human colorectal tumors. IL-6 and interferon-γ were detected by enzyme-linked immunosorbent assay (ELISA). …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30470por Ho, Khanh-Van, Schreiber, Kathy L., Vu, Danh C., Rottinghaus, Susan M., Jackson, Daniel E., Brown, Charles R., Lei, Zhentian, Sumner, Lloyd W., Coggeshall, Mark V., Lin, Chung-Ho“…Of the 13 cytokines [interleukin (IL)-1β, tumor necrosis factor alpha (TNF-α), monocyte chemoattractant protein (MCP)-1, IL-6, IL-8, IL-10, IL-12, IL-17, IL-18, IL-23, IL-33, interferon (IFN)-α, IFN-γ] measured, only six were detected under the culture conditions. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30471“…In comparison with control diet, both LP diets decreased protein expressions of Toll-like receptor-4, nuclear factor-κB, interleukin-1β and tumor necrosis factor-α, and LPC diet further decreased protein expressions of nucleotide-binding oligomerization domain protein-1 and interferon-γ. LPC diet also increased protein expressions of G-protein coupled receptor-43, interleukin-4, transforming growth factor-β, immunoglobulin A and mucin-4, which are indicators for mucosal defense activity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30472por Zare, Nasrin, Javanmard, Shaghayegh Haghjooy, Mehrzad, Valiollah, Eskandari, Nahid, Andalib, Alireza“…Percentages of NK cells expressing CD69, NKG2D and CD16, NK cell cytotoxicity and NK cell proliferation (using flow-cytometry) as well as interferon-gamma (IFN-γ) level in the supernatant of NK cells using ELISA were also investigated. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30473por Alonso-Hearn, Marta, Canive, Maria, Blanco-Vazquez, Cristina, Torremocha, Rosana, Balseiro, Ana, Amado, Javier, Varela-Martinez, Endika, Ramos, Ricardo, Jugo, Begoña M., Casais, Rosa“…Among the DE genes in the PB and ICV samples, there were some common genes irrespective of the type of lesion including the C-X-C motif chemokine ligand 8 (CXCL8/IL8), apolipoprotein L (APOLD1), and the interferon inducible protein 27 (IFI27). The biological processes (BP) enriched in the PB gene expression profiles from the cows with diffuse lesions included the killing of cells of other organism, defense response, immune response and the regulation of neutrophil chemotaxis. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30474por Tsutsumi, Shuntaro, Sato, Tomoo, Yagishita, Naoko, Yamauchi, Junji, Araya, Natsumi, Hasegawa, Daisuke, Nagasaka, Misako, Coler-Reilly, Ariella L. G., Inoue, Eisuke, Takata, Ayako, Yamano, Yoshihisa“…Every year, oral steroid treatment was administered in 48.2–50.7% of the HAM-net-registered patients and interferon-α treatment was used in 2.6–3.5% of patients. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30475por Jagger, Brett W, Dowd, Kimberly A, Chen, Rita, Desai, Pritesh, Himansu, Sunny, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S“…Antibody responses were assayed, and immunized mice were mated and WT mice were transiently immunocompromised by administration of interferon blocking antibody, followed by ZIKV challenge. 1 week post-infection, ZIKV burden was measured via qRT-PCR. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30476por Manion, Maura, Lynn, Niamh, Pei, Luxin, Hammoud, Dima, Laidlaw, Elizabeth, Roby, Gregg, Metzger, Dorinda, Mejia, Yolanda, Lisco, Andrea, Bergin, Colm, Sereti, Irini“…No CD4 T-cell cytokine response to M. genevense genavense was detected (Fig 1). He received interferon-g and optimization of his antimycobacterial regimen with improvement of symptoms and decreased pathogen burden on repeated biopsies. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30477“…HCV treatment status was defined as prescription of pegylated interferon (PEG)/ribavirin (RBV) for >24 weeks, PEG/RBV plus boceprevir or telaprevir, or a newer DAA regimen for >8 weeks. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30478por Habuka, Rie, Aizawa, Yuta, Izumita, Ryohei, Domon, Hisanori, Terao, Yutaka, Saitoh, Akihiko“…Serum levels of proinflammatory cytokines/chemokines (fractalkine, interferon-α2, interleukin [IL]-1 receptor α, IL-6, IL-8, and IL-15) were significantly higher in PeV-A3-infected patients than in EV-infected patients (P < 0.005). …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30479“…Treatment regimens used were: Sofosbuvir (SOF)/ribavirin (RBV)/pegylated interferon (PEG-IFN), 25.2%; SOF/RBV, 62.4%; SOF/RBV/daclatasavir (DCL), 10.6%; SOF/DCL, 2.0%. …”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
30480por Gans, Hayley, Wang, Weiqi, Rosenberg-Hasson, Yael, Zerbo, Ousseny, Modaressi, Sharareh, Goddard, Kristin, Lewis, Ned, Bok, Karin, Klein, Nicola“…The mean percentage of children with increased and decreased concentrations (pg/mL) of signature CD 4+ T-cell Th1 (tumor necrosis factor alpha [TNFa], interferon gamma [IFNg]), Th2 (Interleukin [IL] IL5, IL4, IL13), T(reg) (IL10, transforming growth factor-β TCFb) and DC (IL12P40 and IL12P70) cytokines were equivalent when measured at 42 days after MMR vaccine compared with levels before vaccine (Table 1) (P ≥ 0.05 for all comparisons). …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto