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30501por Ortiz-Romero, Pablo Luis, Servitje, Octavio, Estrach, María Teresa, Izu-Belloso, Rosa María, Fernández-de-Misa, Ricardo, Gallardo, Fernando, López-Martínez, Noemí, Pérez-Mitru, Alejandro“…Costs for the assessed systemic treatments alone or in combination with SDT at 1, 3 and 6 months, were: Systemic retinoids [€2,026.03, €5,206.63 and €7,426.42]; Systemic retinoids + PUVA phototherapy [€3,066.50, €8,271.26 and €10,046.58]; Interferon alfa + PUVA phototherapy [€1,541.09, €5,167.57 and €6,404.55]. …”
Publicado 2020
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30502por Barré, Tangui, Marcellin, Fabienne, Di Beo, Vincent, Delorme, Jessica, Rojas Rojas, Teresa, Mathurin, Philippe, Protopopescu, Camelia, Bailly, François, Coste, Marion, Authier, Nicolas, Carrieri, Maria Patrizia, Rolland, Benjamin“…We investigated whether the arrival of new and well‐tolerated HCV treatments (direct‐acting antivirals: DAA) has improved HCV treatment uptake in French PWID compared with former treatments (pegylated interferon‐based treatments: Peg‐IFN). DESIGN: Using discrete‐time Cox proportional hazards models based on exhaustive care delivery data, we tested for associations between AUD (defined by AUD‐related long‐term illness status, diagnosis coding during hospitalization and/or AUD pharmacological treatment) and first HCV treatment delivery, after adjusting for gender, age, complementary universal health cover, liver disease severity and type of opioid agonist therapy (OAT) received. …”
Publicado 2019
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30503por Ma, Jingjiao, Wu, Rujuan, Xu, Guanlong, Cheng, Yuqiang, Wang, Zhaofei, Wang, Heng’an, Yan, Yaxian, Li, Jinxiang, Sun, Jianhe“…To further explore the potential mechanism, the type I interferon (IFN-I) antagonistic activity of the three NS1 proteins (NS1-108Q, NS1-108R, and NS1-wt) was compared in cells, which showed that the K108R mutation significantly attenuated the IFN-β antagonistic activity of the NS1 protein compared with NS1-wt and NS1-108Q. …”
Publicado 2020
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30504por Jiang, Tingwang, Huang, Yuanlan, Liu, Haohao, Xu, Qiangwei, Gong, Yanping, Chen, Yao, Hu, Xiaowei, Han, Zhijun, Gao, Mingzhu“…Real-time PCR and Western blot analysis were conducted to determine the expression levels of miR-146a, interferon gamma (IFN-γ), interleukin (IL)-17A, and REG3A. …”
Publicado 2020
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30505por Davis, Renee, Taylor, Alex, Nally, Regan, Benson, Kathleen F, Stamets, Paul, Jensen, Gitte S“…The solid fraction was the most potent inducer of Tumor Necrosis Factor-α, as well as the anti-viral cytokines interferon-γ, MCP-1 (CCL-2), MIP-1α (CCL-3), and MIP-1β (CCL-4), and induced G-CSF and b-FGF—growth-factors involved in regenerative functions—and the anti-inflammatory cytokine IL-1ra. …”
Publicado 2020
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30506por Rocco, Joseph M, York, Zachary, Shen, Chengli, Shiboski, Caroline, Cyriaque-Webster, Jennifer, McLaughlin, Janet, Borowski, Luann, Chen, Huichao, Aberg, Judith A, Dittmer, Dirk P, Ghannoum, Mahmoud, Rinaldo, Charles R, Macatangay, Bernard“…RESULTS: St A participants had higher levels of interleukin (IL)-1β, IL-6, IL-17, tumor necrosis factor alpha (TNFα), and interferon gamma (IFNγ) compared with St B and D (P = .02; P < .0001) but were not different from St C. …”
Publicado 2020
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30507por Wu, Mengjun, Zhang, Qian, Yi, Dan, Wu, Tao, Chen, Hongbo, Guo, Shuangshuang, Li, Siyuan, Ji, Changzheng, Wang, Lei, Zhao, Di, Hou, Yongqing, Wu, Guoyao“…Pathway analyses revealed that PR restored the expression of several interferon-stimulated genes and selectively upregulated the expression of guanylate-binding proteins. …”
Publicado 2020
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30508por Zhang, Ling, Davies, John S, Serna, Carylinda, Yu, Zhiya, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A, Hinrichs, Christian S“…In each of two transgenic murine tumor models, tumor-specific T cells constitutively expressing aIL-12 demonstrated increased antitumor efficacy, low circulating IL-12 and interferon-γ, and no weight loss. Expression of aIL-12 via a NFAT-inducible promoter resulted in coordinate expression of aIL-12 with T cell activation. …”
Publicado 2020
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30509por Santos, João Manuel, Heiniö, Camilla, Cervera-Carrascon, Victor, Quixabeira, Dafne C A, Siurala, Mikko, Havunen, Riikka, Butzow, Ralf, Zafar, Sadia, de Gruijl, Tanja, Lassus, Heini, Kanerva, Anna, Hemminki, Akseli“…Tumor reactivity was assessed by determining interferon gamma (IFNg) response of clinically relevant TILs towards autologous T-cell-depleted ex vivo tumor cultures pretreated with or without the aforementioned oncolytic adenoviruses. …”
Publicado 2020
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30510por Li, Guanfei, Yang, Lihua, Li, Dan, Zhang, Jinhong, Du, Ling, Xia, Libin, Liu, Yunhua, Hu, Wanqin“…The number of MHC-II(+), CD80(+) and CD86(+) bone marrow-derived dendritic cells (DCs) generated by female mice, and the levels of tumor necrosis factor-α and interferon-γ in the spleens of female mice were significantly decreased in the PD-L1 Ig + CD40L mAb group compared with the spontaneous abortion group. …”
Publicado 2020
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30511por Nettis, M. A., Veronese, M., Nikkheslat, N., Mariani, N., Lombardo, G., Sforzini, L., Enache, D., Harrison, N. A., Turkheimer, F. E., Mondelli, V., Pariante, C. M.“…In seven healthy males, we used repeated translocator protein-Positron Emission Tomography (TSPO-PET) dynamic scans with [(11)C]PBR28 to image brain microglial activation before and 24 h after the immune challenge interferon (IFN)-α. We also investigated the association between changes in peripheral inflammation, changes in microglial activity, and changes in mood. …”
Publicado 2020
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30512por González‐Tajuelo, Rafael, de la Fuente‐Fernández, María, Morales‐Cano, Daniel, Muñoz‐Callejas, Antonio, González‐Sánchez, Elena, Silván, Javier, Serrador, Juan Manuel, Cadenas, Susana, Barreira, Bianca, Espartero‐Santos, Marina, Gamallo, Carlos, Vicente‐Rabaneda, Esther F., Castañeda, Santos, Pérez‐Vizcaíno, Francisco, Cogolludo, Ángel, Jiménez‐Borreguero, Luis Jesús, Urzainqui, Ana“…Importantly, we found expanded populations of interferon‐γ–producing PSGL‐1(−/−) T cells and B cells and a reduced presence of regulatory T cells. …”
Publicado 2020
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30513por Seamon, Kimberly, Kurlak, Lesia O., Warthan, Michelle, Stratikos, Efstratios, Strauss, Jerome F., Mistry, Hiten D., Lee, Eun D.“…The immune cells from PE released elevated expressions of interleukin (IL)-2, IL-4, and most notably, pro-inflammatory IL-13 and IL-17α, inflammatory cytokines tumor necrosis factor (TNF)-α and interferon (IFN)-γ, and granulocyte-macrophage colony-stimulating factor (GM-CSF) compared to normal peripheral blood mononuclear cells (PBMCs). …”
Publicado 2020
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30514por Rádiková, Žofia, Penesová, Adela, Vlček, Miroslav, Havranová, Andrea, Siváková, Monika, Šiarnik, Pavel, Žitňanová, Ingrid, Imrich, Richard, Turčáni, Peter, Kollár, Branislav“…Serum levels of interleukin (IL) 1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-13, IL-17, granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor, interferon-γ and TNF-α were measured by multiplex bead assay. …”
Publicado 2020
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30515“…The effect of BVDV-induced autophagy on the survival of BVDV-infected host cell, cell apoptosis, and interferon (IFN) signalling was studied by flow cytometric analysis and quantitative RT-(q)PCR using shBCN1-MDBK cells. we found that infection with either CP or NCP BVDV strains induced steady-state autophagy in MDBK cells, as evident by the increased number of double- or single-membrane vesicles, the accumulation of GFP- microtubule-associated protein 1 light chain 3 (LC3) dots, and the conversion of LC3-I (cytosolic) to LC3-II (membrane-bound) forms. …”
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30516por Szymura, Szymon J., Bernal, Giovanna M., Wu, Longtao, Zhang, Zhongqin, Crawley, Clayton D., Voce, David J., Campbell, Paige-Ashley, Ranoa, Diana E., Weichselbaum, Ralph R., Yamini, Bakhtiar“…Finally, genome-wide analysis demonstrated that despite the link to the PRR system, DDX39B did not generally inhibit interferon-stimulated gene expression, but rather acted to attenuate expression of factors associated with the extracellular matrix, cellular migration, and angiogenesis. …”
Publicado 2020
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30517por Hozain, Ahmed E., Tipograf, Yuliya, Pinezich, Meghan R., Cunningham, Katherine M., Donocoff, Rachel, Queen, Dawn, Fung, Kenmond, Marboe, Charles C., Guenthart, Brandon A., O'Neill, John D., Vunjak-Novakovic, Gordana, Bacchetta, Matthew“…In bronchoalveolar lavage fluid, granulocyte-macrophage colony-stimulating factor, interleukin (IL) 4, IL-6, and IL-10 levels increased less than 6-fold, whereas interferon gamma, IL-1α, IL-1β, IL-1ra, IL-2, IL-8, IL-12, IL-18, and tumor necrosis factor alpha levels decreased from baseline to day 4. …”
Publicado 2020
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30518por Gao, Yong-hua, Guan, Wei-jie, Xu, Gang, Lin, Zhi-ya, Tang, Yan, Lin, Zhi-min, Gao, Yang, Li, Hui-min, Zhong, Nan-shan, Zhang, Guo-jun, Chen, Rong-chang“…In receiver operating characteristics analysis, serum interferon-γ-induced protein 10 yielded an area under curve of 0.67 (95' CI, 0.53-0.77; P = .018). …”
Publicado 2015
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30519por Cerri, R.L.A., Thompson, I.M., Kim, I.H., Ealy, A.D., Hansen, P.J., Staples, C.R., Li, J.L., Santos, J.E.P., Thatcher, W.W.“…Genes up- and downregulated in pregnant cows were associated with several gene ontology terms, such as defense response and interferon regulatory factor, cell adhesion, and extracellular matrix. …”
Publicado 2012
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30520por Hsu, Wei-Fan, Chen, Chi-Yi, Tseng, Kuo-Chih, Lai, Hsueh-Chou, Kuo, Hsing-Tao, Hung, Chao-Hung, Tung, Shui-Yi, Wang, Jing-Houng, Chen, Jyh-Jou, Lee, Pei-Lun, Chien, Rong-Nan, Lin, Chun-Yen, Yang, Chi-Chieh, Lo, Gin-Ho, Tai, Chi-Ming, Lin, Chih-Wen, Kao, Jia-Horng, Liu, Chun-Jen, Liu, Chen-Hua, Yan, Sheng-Lei, Bair, Ming-Jong, Su, Wei-Wen, Chu, Cheng-Hsin, Chen, Chih-Jen, Lo, Ching-Chu, Cheng, Pin-Nan, Chiu, Yen-Cheng, Wang, Chia-Chi, Cheng, Jin-Shiung, Tsai, Wei-Lun, Lin, Han-Chieh, Huang, Yi-Hsiang, Tsai, Pei-Chien, Huang, Jee-Fu, Dai, Chia-Yen, Chuang, Wan-Long, Yu, Ming-Lung, Peng, Cheng-Yuan“…In patients with chronic hepatitis C (CHC), the effects of baseline characteristics, virological profiles, and therapeutic outcome to pegylated interferon plus ribavirin (PR) therapy on autoimmune diseases are unknown. …”
Publicado 2020
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