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31081por Menotti, Sara, Giampietro, Antonella, Raia, Salvatore, Veleno, Miriam, Angelini, Flavia, Tartaglione, Tommaso, Gaudino, Simona, Doglietto, Francesco, De Marinis, Laura, Pontecorvi, Alfredo, Bianchi, Antonio, Chiloiro, Sabrina“…A cytokine array shows the presence of gamma-interferon and interleukin-17. Patients carrying mutations in the PIT1 or PROP1 genes may present PAH. …”
Publicado 2023
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31082por Qiu, Luying, Wang, Yaxuan, Wang, Yuye, Liu, Fang, Deng, Shumin, Xue, Weishuang, Wang, Yanzhe“…We established a co-culture system with SH-SY5Y cells and microglia-conditioned medium (MCM) stimulated by lipopolysaccharide (LPS) and interferon-gamma (IFNγ). MMP9 and TIMP1 levels were measured with ELISA assay to confirm the UA effect. …”
Publicado 2023
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31083por Natoli, Valentina, Charras, Amandine, Hofmann, Sigrun R., Northey, Sarah, Russ, Susanne, Schulze, Felix, McCann, Liza, Abraham, Susanne, Hedrich, Christian M.“…To identify genes under the control of interferon (IFN), the Interferome database was consulted, and DNA Methylation Scores were calculated. …”
Publicado 2023
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31084por De Nardi, Laura, Natale, Marco Francesco, Messia, Virginia, Tomà, Paolo, De Benedetti, Fabrizio, Insalaco, Antonella“…A chest Computed Tomography (CT) scan showed bilateral bronchiectasis, parenchymal consolidation and interstitial lung disease; rheumatoid factor and type I interferon signature resulted negative, therefore excluding COatomer Protein subunit Alpha (COPA) syndrome. …”
Publicado 2023
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31085por Han, Feng, Guo, Jiayou, Mu, Mingchen, Bian, Ka, Cui, Zhenting, Duan, Qiong, Ma, Jianxin, Jin, Lai, Liu, Wentao, Chen, Fanghong“…Next, we constructed the H22 tumor-bearing mouse model and observed the abdominal girth, body weight, survival rate, and survival time in each group; we marked the proteins associated with NETs in mouse intestinal tissues by immunofluorescence; cf-DNA and cytokines in ascites such as: tumor necrosis factor alpha (TNF-α), vascular endothelial growth factor (VEGF), interleukin 6 (IL-6), matrix metalloprotein 9 (MMP-9), and interferon gamma (IFN-γ) levels in ascites were measured by enzyme-linked immunosorbent assay. …”
Publicado 2023
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31086por Cui, Wanchang, Hull, Lisa, Zizzo, Alex, Wang, Li, Lin, Bin, Zhai, Min, Xiao, Mang“…Blocking IL-18 using its endogenous binding protein (IL-18BP) increases mice survival after radiation exposure by decreasing bone marrow interferon-gamma levels. METHODS: To further characterize the roles of IL-18 in response to radiation, both wild type and IL-18 knockout (IL-18 KO) mice were exposed to 9.0 Gy total body irradiation (TBI). …”
Publicado 2023
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31087por Wang, Juan, Chen, Guiming, Li, Lei, Luo, Sidan, Hu, Bingrong, Xu, Jia, Luo, Haihua, Li, Shan, Jiang, Yong“…The dynamic profile of interferon γ (IFNγ)-inducible protein 10 (IP-10) mRNA expression induced by macrophage MRP8/14 was determined by quantitative real-time polymerase chain reaction (qPCR). …”
Publicado 2023
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31088“…RESULTS: On day 5 of surgery, the expression values of interferon gamma (increased 7.2-fold, P < .01), tumor necrosis factor alpha (increased 13-fold, P < .05), interleukin-1β (increased 4.7-fold, P < .001), and interleukin-6 (increased 4.6-fold, P < .01) increased significantly in the metformin group compared with those in the control group. …”
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31089por kotb, Raghda R., Afifi, Ahmed M., EL-Houseini, Motawa E., Ezz-Elarab, Mohamed, Basalious, Emad B., Omran, Mervat M., Abdellateif, Mona S.“…Patients were assessed after each month (cycle) for the plasma levels of CD4, CD8, CD25, Interleukins-2 (IL-2), IL-6, IL-12, Interferon-gamma (IFN- γ), Lactate dehydrogenase (LDH), and Vascular endothelial growth factor (VEGF), FOXP3 mRNA, and miRNA 21. …”
Publicado 2023
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31090por Coles, Alasdair J., Achiron, Anat, Traboulsee, Anthony, Singer, Barry A., Pozzilli, Carlo, Oreja-Guevara, Celia, Giovannoni, Gavin, Comi, Giancarlo, Freedman, Mark S., Ziemssen, Tjalf, Shiota, Debora, Rawlings, Andreea M., Wong, Alana T., Chirieac, Magdalena, Montalban, Xavier“…BACKGROUND AND OBJECTIVES: Alemtuzumab demonstrated superior efficacy versus subcutaneous interferon (IFN) beta-1a in participants with relapsing-remitting multiple sclerosis in the 2-year CARE-MS I and II trials. …”
Publicado 2023
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31091por Lian, Jing, Lin, Dongxin, Huang, Yuchan, Chen, Xiaohui, Chen, Lian, Zhang, Fan, Tang, Peiling, Xie, Jinling, Hou, Xiaotao, Du, Zhengcai, Deng, Jiagang, Hao, Erwei, Liu, Junhui“…This review aims to encapsulate the array of representative factors within the tumour’s inflammatory microenvironment, such as interleukins (IL-6, IL-10, IL-17, IL-1β), transforming growth factor-beta (TGF-β), interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α), vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMPs). …”
Publicado 2023
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31092por Husso, Aleksi, Pessa-Morikawa, Tiina, Koistinen, Ville Mikael, Kärkkäinen, Olli, Kwon, Hyuk Nam, Lahti, Leo, Iivanainen, Antti, Hanhineva, Kati, Niku, Mikael“…RESULTS: In the fetal intestine, critical genes mediating host-microbe interactions, innate immunity, and epithelial barrier were differentially expressed. Interferon and inflammatory signaling genes were downregulated in the intestines and brains of the fetuses from germ-free dams. …”
Publicado 2023
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31093por Imtiaz rafiqi, Shafiya, Zahid, Zeeshan, Lamendella, Regina, aghogho, olomukoro, Gionfriddo, Emanuela, Tao, Yang, Jaume, Juan C, Imam, Shahnawaz“…The enrichment of Tregs leads to the regulation of diabetogenic Th1, Th17, and interferon gamma-producing CD8 T cells (cytotoxic lymphocytes, CTLs) at PLN, PN, and spleen. …”
Publicado 2023
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31094por Li, Xiaowei, Wang, Hong, Zhang, Qidi, Sun, Xiaobin, Zhang, Mengyuan, Wang, Gongming“…After surgery, T lymphocytes, the majority of which were CD8 + T cells, infiltrated the hippocampus and secreted Interferon-γ (IFN-γ). Depletion of CD8 + T cells could inhibit the increase of IFN-γ synthesis, improve hippocampal neurogenesis, and improve postoperative cognitive function. …”
Publicado 2023
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31095“…Enrichment and immune infiltration analysis showed interferon signaling and cytokine-cytokine receptor interaction enriched in the LYRM4-AS1 high-expression phenotype, and LYRM4-AS1 showed significantly positively related to immune infiltration as well as immune checkpoints (P < 0.01). …”
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31096por Saura‐Lázaro, Anna, Bock, Peter, van den Bogaart, Erika, van Vliet, Jessie, Granés, Laura, Nel, Kerry, Naidoo, Vikesh, Scheepers, Michelle, Saunders, Yvonne, Leal, Núria, Ramponi, Francesco, Paulussen, René, de Wit, Tobias Rinke, Naniche, Denise, López‐Varela, Elisa“…INTRODUCTION: Antiretroviral therapy (ART) monitoring using viral load (VL) testing is challenging in high‐burden, limited‐resources settings. Chemokine IP‐10 (interferon gamma‐induced protein 10) strongly correlates with human immunodeficiency virus (HIV) VL. …”
Publicado 2023
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31097“…Meanwhile, high CCDC69 expression can predict better immunotherapy responses when compared with low CCDC69 expression. After the interferon-gamma treatment, the CCDC69 expression was elevated in vitro. …”
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31098por Barbosa, Jéssica Anastácia Silva, da Silva, Luana Laura Sales, João, Juliana Morelli Lopes Gonçalves, de Campos, Elaine Cristina, Fukuzaki, Silvia, Camargo, Leandro do Nascimento, dos Santos, Tabata Maruyama, dos Santos, Henrique Tibucheski, Bezerra, Suellen Karoline Moreira, Saraiva-Romanholo, Beatriz Mangueira, Lopes, Fernanda Degobbi Tenório Quirino dos Santos, Bonturi, Camila Ramalho, Oliva, Maria Luiza Vilela, Leick, Edna Aparecida, Righetti, Renato Fraga, Tibério, Iolanda de Fátima Lopes Calvo“…We evaluated the hyperresponsiveness to methacholine, exhaled nitric oxide, bronchoalveolar lavage fluid (BALF), mean linear intercept (Lm), inflammatory markers, tumor necrosis factor (TNF-α), interferon (IFN)), matrix metalloproteinases (MMPs), growth factor (TGF-β), collagen fibers, the oxidative stress marker inducible nitric oxide synthase (iNOS), transcription factors, and the signaling pathway NF-κB in the airways (AW) and alveolar septa (AS). …”
Publicado 2023
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31099por Zhang, Junmei, Sun, Li, Shi, XinWei, Li, Shipeng, Liu, Cuihua, Li, Xiaoqing, Lu, Meiping, Deng, Jianghong, Tan, Xiaohua, Guan, Wanzhen, Li, Guomin, Wen, Xinran, Liu, Ping, Li, Caifeng“…Existing research has suggested that interferon and Janus kinase played an important role in pathogenesis. …”
Publicado 2023
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31100por Zhang, Caihui, Yu, Zhongxun, Gao, Sihao, Ma, Mingsheng, Gou, Lijuan, Wang, Changyan, Wang, Lin, Li, Ji, Zhong, Linqing, Zhou, Yu, Wang, Wei, Song, Hongmei“…RESULTS: A total of 16 patients entered this study, including 3 with Aicardi-Goutières syndrome (AGS), 4 Blau syndrome, 2 chronic infantile neurologic cutaneous articular syndrome (CINCA), 2 A20 haploinsufficiency (HA20), 1 adenosine deaminase 2 deficiency(DADA2), 1 familial Mediterranean fever (FMF),1 tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS), 1 PLCγ2-associated antibody deficiency and immune dysregulation (PLAID), and 1 stimulator of interferon genes-associated vasculopathy with onset in infancy(SAVI). …”
Publicado 2023
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