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31101por Yukawa, Kayo, Yamamoto-Mcguire, Satomi, Cafaro, Louis, Hong, Christine, Kamme, Fredrik, Ikezu, Tsuneya, Ikezu, Seiko“…RNA-sequence analysis of the temporal cortex tissue revealed significant enrichment of interferon-gamma and complement pathways and increased expression of antigen presenting molecules (Cd86, Cd74, and H2-Aa) in PS19 mice treated with ASO-Ttbk1, suggesting its potential effect on microglial phenotype although neurotoxic effect was absent. …”
Publicado 2023
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31102por Huang, Chung-Guei, Wu, Yi-Cheng, Hsieh, Ming-Ju, Lin, Ya-Jhu, Hsieh, Tzu-Hsuan, Huang, Po-Wei, Yang, Shu-Li, Tsao, Kuo-Chien, Shih, Shin-Ru, Lee, Li-Ang“…Age emerged as a modulating factor, dampening innate immune reactions, as evidenced by reduced interleukin-2 and interferon-γ concentrations (both adjusted P < 0.05). …”
Publicado 2023
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31103por Bella, Ángela, Arrizabalaga, Leire, Di Trani, Claudia Augusta, Gonzalez-Gomariz, Jose, Gomar, Celia, Russo-Cabrera, Joan Salvador, Olivera, Irene, Cirella, Assunta, Fernandez-Sendin, Myriam, Alvarez, Maite, Teijeira, Alvaro, Atay, Cigdem, Medina-Echeverz, José, Hinterberger, Maria, Hochrein, Hubertus, Melero, Ignacio, Berraondo, Pedro, Aranda, Fernando“…RESULTS: Intraperitoneal or locoregional administration, but not other routes of administration, resulted in a potent immune response characterized by increased levels of tumor-specific CD8(+) T lymphocytes with the ability to produce both interferon-γ and tumor necrosis factor-α. The antitumor immune response was detectable not only in the peritoneal cavity but also systemically. …”
Publicado 2023
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31104por Ling, Xinyu, Wei, Shiyou, Ling, Dandan, Cao, Siqi, Chang, Rui, Wang, Qiuyun, Yuan, Zhize“…It was then found that Srg3 can be transcriptionally activated by interferon regulatory factor 7 (Irf7), and specific inhibition of Irf7 significantly improved the symptoms of ALI. …”
Publicado 2023
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31105por Evans, Jason V, Suman, Shankar, Goruganthu, Mounika Uttam L, Tchekneva, Elena E, Guan, Shuxiao, Arasada, Rajeswara Rao, Antonucci, Anneliese, Piao, Longzhu, Ilgisonis, Irina, Bobko, Andrey A, Driesschaert, Benoit, Uzhachenko, Roman V, Hoyd, Rebecca, Samouilov, Alexandre, Amann, Joseph, Wu, Ruohan, Wei, Lai, Pallerla, Aaditya, Ryzhov, Sergey V, Feoktistov, Igor, Park, Kyungho P, Kikuchi, Takefumi, Castro, Julio, Ivanova, Alla V, Kanagasabai, Thanigaivelan, Owen, Dwight H, Spakowicz, Daniel J, Zweier, Jay L, Carbone, David P, Novitskiy, Sergey V, Khramtsov, Valery V, Shanker, Anil, Dikov, Mikhail M“…A(2B)-adenosine receptor inhibition alleviated metabolic stress, downregulated expression of adenosine-generating ectonucleotidases, increased expression of adenosine deaminase, decreased tumor growth and metastasis, increased interferon γ production, and enhanced the efficacy of antitumor therapies following combination regimens in animal models (anti–programmed cell death 1 protein vs anti–programmed cell death 1 protein plus PBF-1129 treatment hazard ratio = 11.74 [95% confidence interval = 3.35 to 41.13], n = 10, P < .001, 2-sided F test). …”
Publicado 2023
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31106por Ye, Lin, Wang, Yizhong, Xiao, Fangfei, Wang, Xufei, Li, Xiaolu, Cao, Rong, Zhang, Jiayue, Zhang, Ting“…Furthermore, Fp-EVs downregulated the expression of the proinflammatory cytokines interleukin-1β (IL-1β), IL-2, IL-6, IL-12a, IL-17a, Interferon-γ (IFN-γ), tumor necrosis factor - α (TNF-α), granulocyte-macrophage colony stimulating factor (GM-CSF) and upregulated the anti-inflammatory cytokines IL-4, IL-10, and transforming growth factor β (TGF-β) in DSS-treated mice. …”
Publicado 2023
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31107por Verdegaal, Els M E, Santegoets, Saskia J, Welters, Marij J P, de Bruin, Linda, Visser, Marten, van der Minne, Caroline E, de Kok, Pita M, Loof, Nikki M, Boekestijn, Sanne, Roozen, Inge, Westra, Inge M, Meij, Pauline, Van der Burg, Sjoerd H, Kroep, Judith R“…Patients were treated in two cohorts with or without interferon-α (IFNa), as conditioning and TIL support regimen. …”
Publicado 2023
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31108“…He tested negative for ANA, HIV, Hepatitis C, Mycobacterium TB Interferon-Gamma. The patient underwent skin biopsy and excisional lymph node biopsy. …”
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31109por Davis, M. J., Martin, R. E., Pinheiro, G. M., Hoke, E. S., Moyer, S., Ueno, K., Rodriguez-Gil, J. L., Mallett, M. A., Khillan, J. S., Pavan, W. J., Chang, Y. C., Kwon-Chung, K. J.“…The infection pathobiology in SJL/J mice and susceptible mice was similar for the first 7–10 days then markedly diverged toward pathogen clearance. Interferon-gamma (IFN-γ) expression was critical for SJL/J resistance while tumor necrosis factor-alpha was also important. …”
Publicado 2023
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31110por Schutt, William R., Conde, Jonas N., Mladinich, Megan C., Himmler, Grace E., Mackow, Erich R.“…ZIKV persistence requires inhibiting interferon (IFN) responses that direct viral clearance. …”
Publicado 2023
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31111por Xie, Ye, Yao, Jia, Yan, Mengchao, Lin, Yan, Wei, Jiayun, Wang, Haiping, Mao, Yongcui, Liu, Pinyan, Li, Xun“…Using immunohistochemistry, quantitative polymerase chain reaction, and immunofluorescence techniques, we evaluated the therapeutic effect of UC-MSCs pretreated with interferon alpha 2 (IFN-α2) (pre-MSCs) in an animal model of cirrhosis. …”
Publicado 2023
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31112por Yankelevich, Maxim, Thakur, Archana, Modak, Shakeel, Chu, Roland, Taub, Jeffrey, Martin, Alissa, Schalk, Dana L., Schienshang, Amy, Whitaker, Sara, Rea, Katie, Lee, Daniel W., Liu, Qin, Shields, Anthony, Cheung, Nai-Kong, Lum, Lawrence G.“…More than 50% of evaluable patients showed augmented immune responses to GD2+ targets after GD2BATs as measured by interferon-gamma (IFN-γ) EliSpots, Th1 cytokines, and/or chemokines. …”
Publicado 2023
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31113por Huang, Yating, Zhang, Qiuwan, Cao, Wenjiao, Zhang, Qinyu, Wang, Lulu, Lai, Dongmei“…Moreover, we investigated whether activated hAECs stimulated by the proinflammatory cytokines tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) were more effective than native hAECs in repairing ovarian injury induced by chemotherapy. …”
Publicado 2023
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31114por Skarbinski, Jacek, Ni, Yuching, Wick, Jenna M, Chitnis, Amit S, Krueger, Amy L, Jaganath, Devan, Wong, Robert J, Halmer, Nicole“…TB infection screening was defined as testing with interferon gamma release assay or tuberculin skin test. …”
Publicado 2023
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31115“…The most significantly regulated gene set of each miRNA related to cell cycle (hsa-miRNA-144-3p and -5p [P(adj) = 4 × 10(−40) and P(adj) = 4 × 10(−6)], -miR-17-5p [P(adj) = 9.5 × 10(−23)], -miR-30e-5p [P(adj) = 8.2 × 10(−18)], -miR-130a-3p [P(adj) = 5 × 10(−15)]), integrin cell surface interaction (-miR-223-3p [P(adj) = 2.4 × 10(−7)]), and interferon signaling (-miR-142-3p [P(adj) = 5 × 10(−11)]). …”
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31116por Yu, Yeping, Chang, Ling, Hu, Qingluan, Zhu, Jianjun, Zhang, Jianjun, Xia, Qiang, Zhao, Jie“…Administration of DMX, the activator of stimulator of interferon genes (STING), was performed to investigate the effects of the STING-related pathway on APAP-treated P2rx1(−/−) mice. …”
Publicado 2023
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31117por Wang, Lei, Zhang, Guoan, Sun, Wenjie, Zhang, Yan, Tian, Yi, Yang, Xiaohui, Liu, Yingfu“…These genes were organized into seven co-expression modules associated with relevant pathways, including interferon signaling, T-cell receptor signaling, and specific granule pathways. …”
Publicado 2023
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31118por Apte, Sachin M, Vadhan-Raj, Saroj, Cohen, Lorenzo, Bassett, Roland L, Gordon, Ilyssa O, Levenback, Charles F, Ramirez, Pedro T, Gallardo, Stacie T, Patenia, Rebecca S, Garcia, Michael E, Iyer, Revathy B, Freedman, Ralph S“…A priming and post-chemotherapy schedule of the myeloid cell mobilizing and immune stimulatory growth factor, granulocyte monocyte stimulating factor (GM-CSF, Leukine(®)) and the MO/MA activating cytokine recombinant interferon gamma 1b (rIFN-γ1b, Actimmune(®)) has been developed. …”
Publicado 2006
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31119“…Several cytokines--interleukin 2 (IL-2), tumour necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma)--and prostaglandin E2 (PGE2) known to modulate tumour growth and metastasis were examined to determine whether they regulate nm23 expression in JAR in vitro. …”
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31120por Kroesen, B. J., Buter, J., Sleijfer, D. T., Janssen, R. A., van der Graaf, W. T., The, T. H., de Leij, L., Mulder, N. H.“…Elevated plasma levels of tumour necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) were detected at the MTD. …”
Publicado 1994
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