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31341por Wang, Miaomiao, Liniger, Matthias, Muñoz-González, Sara, Bohórquez, José Alejandro, Hinojosa, Yoandry, Gerber, Markus, López-Soria, Sergio, Rosell, Rosa, Ruggli, Nicolas, Ganges, Llilianne“…The vPdR-5U-infected piglets showed only transient alpha interferon (IFN-α) responses in serum after 1 week of infection, while the vPdR-36U-infected piglets showed sustained IFN-α levels during the first 2 weeks. …”
Publicado 2020
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31342por Dreschers, Stephan, Ohl, Kim, Schulte, Nora, Tenbrock, Klaus, Orlikowsky, Thorsten W.“…Interleukin-10 (IL10) and Interferon-gamma (IFNy) further differentiate MΦ subpopulations, the anti-inflammatory MΦ-IL10 and the pro-inflammatory MΦ-IFNy subtype. …”
Publicado 2020
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31343por Matsuoka, Naoki, Fujita, Yuya, Temmoku, Jumpei, Furuya, Makiko Yashiro, Asano, Tomoyuki, Sato, Shuzo, Matsumoto, Haruki, Kobayashi, Hiroko, Watanabe, Hiroshi, Suzuki, Eiji, Kozuru, Hideko, Yastuhashi, Hiroshi, Migita, Kiyoshi“…BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by elevated interferon (IFN) signature genes. Galectin-9 (Gal-9) is a β-galactoside-binding lectin that is reportedly useful as a biomarker for IFN gene signatures. …”
Publicado 2020
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31344“…Additionally, B. subtilis-Cap inoculation resulted in increased the expression of TLR2 and TLR9 (P < 0.01), and induced the secretion of cytokines IL-1β, IL-6, interferon-γ, and β-defensin 2 (P < 0.01). CONCLUSIONS: We constructed a prototype PCV2 vaccine that can be administered orally and elicits a more robust humoral and cellular immunity than inactivated PCV2. …”
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31345por Leotta, Salvatore, Sapienza, Giuseppe, Camuglia, Maria Grazia, Avola, Giuseppe, Marco, Annalia Di, Moschetti, Gaetano, Curto Pelle, Angelo, Markovic, Uros, Milone, Giulio Antonio, Cupri, Alessandra, Bianco, Oriana, Frontini, Viviana, Spadaro, Andre, Marchese, Anna Elisa, Crocchiolo, Roberto, Milone, Giuseppe“…We chose a predefined time point, 18 days after hematopoietic stem cell transplantation (HSCT), to measure the levels of six cytokines in the plasma: soluble interleukin-2 receptor alpha (sIL2-Rα), T-cell immunoglobulin domain and mucin domain-3 (TIM-3), suppression of tumorigenicity-2 (ST-2), intercellular adhesion molecule (ICAM-1), interferon-gamma (IFN-γ), and interleukin-6 (IL-6). …”
Publicado 2020
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31346por Sun, Yao, Guo, Yongqing, Feng, Xuejian, Jia, Meng, Ai, Ning, Dong, Yue, Zheng, Yayuan, Fu, Lu, Yu, Bin, Zhang, Haihong, Wu, Jiaxin, Yu, Xianghui, Wu, Hui, Kong, Wei“…In addition, we characterized the absence of macrophage-inflammatory protein (MIP-3α) and the upregulation of interferon (IFN)-γ, interleukin (IL)-5, and IL-6 in the plasma of P301S transgenic mice, which can be served as potential plasma biomarkers in P301S Tg mice. …”
Publicado 2020
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31347por Gibaldi, Daniel, Vilar-Pereira, Glaucia, Pereira, Isabela Resende, Silva, Andrea Alice, Barrios, Leda Castaño, Ramos, Isalira Peroba, Mata dos Santos, Hílton Antônio, Gazzinelli, Ricardo, Lannes-Vieira, Joseli“…Further, T. cruzi-infected ccl3(−/−)mice presented reduced frequency of interferon-gamma (IFNγ)(+) cells and numbers of parasite-specific IFNγ-producing cells, while the T. cruzi antigen-specific cytotoxic activity was increased. …”
Publicado 2020
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31348por Yokoyama-Kokuryo, Waka, Yamazaki, Hayato, Takeuchi, Tsutomu, Amano, Koichi, Kikuchi, Jun, Kondo, Tsuneo, Nakamura, Seiji, Sakai, Ryoko, Hirano, Fumio, Nanki, Toshihiro, Koike, Ryuji, Harigai, Masayoshi“…Gene ontology analysis of the 218 genes identified “response to type I interferon (IFN)” with 24 type I IFN-related genes. …”
Publicado 2020
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31349por Toyoda, Takahide, Kamata, Toshiko, Tanaka, Kazuhisa, Ihara, Fumie, Takami, Mariko, Suzuki, Hidemi, Nakajima, Takahiro, Ikeuchi, Takayuki, Kawasaki, Yohei, Hanaoka, Hideki, Nakayama, Toshinori, Yoshino, Ichiro, Motohashi, Shinichiro“…The geometric mean number of iNKT cells in all cases was significantly decreased and the mean numbers of natural killer (NK) cells, interferon-γ-producing cells in response to αGalCer, and effector CD8+ T cells were significantly increased after the administration of αGalCer-pulsed APCs. …”
Publicado 2020
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31350por Fernández, Rocío D. V., Díaz, Ariana, Bongiovanni, Bettina, Gallucci, Georgina, Bértola, Diego, Gardeñez, Walter, Lioi, Susana, Bertolin, Yésica, Galliano, Romina, Bay, María L., Bottasso, Oscar, D'Attilio, Luciano“…In turn, TB+DM showed even higher levels of interferon gamma -IFN-γ- and hGH (vs. TB), or IL-6, C reactive protein, cortisol and hGH (vs. …”
Publicado 2020
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31351“…Moreover, PSF efficiently decreased the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-4, interferon (IFN)-γ, thromboxane A(2) (TXA(2)), and prostaglandin E(2) (PGE(2)) in lung tissues of mice infected with influenza virus (p < 0.05–0.01). …”
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31352por Li, Wei, Xia, Ying, Yang, Jing, Guo, Haitao, Sun, Guoqing, Sanyal, Arun J., Shah, Vijay H., Lou, Yongliang, Zheng, Xiaoqun, Chalasani, Naga, Yu, Qigui“…Recombinant sHVEM affected tumor necrosis factor (TNF)‐α and interferon‐γ production by T cells from patients with AH and HCs. …”
Publicado 2020
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31353por Heinemann, Nele Carolin, Tischer-Zimmermann, Sabine, Wittke, Torge Christian, Eigendorf, Julian, Kerling, Arno, Framke, Theodor, Melk, Anette, Heuft, Hans-Gert, Blasczyk, Rainer, Maecker-Kolhoff, Britta, Eiz-Vesper, Britta“…The clinical applicability was determined by small-scale T-cell enrichment using interferon- (IFN-) γ cytokine secretion assay and virus-derived overlapping peptide pools. …”
Publicado 2020
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31354“…In particular, these cells doubled their expression of the pleiotropic cytokines, interleukin-4 and interleukin-12 after FIV infection. Interferon-γ production also increased after infection with FIV whereas, TNFα expression remained constant. …”
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31355“…Another recently discovered family of sensor called stimulator of interferon (IFN) genes (STING), specifically houses on the endoplasmic reticulum (ER) and functions in association with its upstream sensor, cGAS. …”
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31356por Deutsch, Liat, Houri, Inbal, Ben-Ari, Ziv, Shlomai, Amir, Veitsman, Ella, Cohen-Ezra, Oranit, Issachar, Assaf, Mor, Orna, Gozlan, Yael, Bruck, Rafael, Menachem, Yoram, Zelber-Sagi, Shira, Katchman, Helena, Shibolet, Oren“…Treatment with first generation protease inhibitors (PI) + peg-interferon (pegIFN) and ribavirin (RBV) achieved sustained virologic response (SVR) rates of 65–75% but was associated with multiple side effects. …”
Publicado 2020
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31357“…All children received interferon alfa by aerosolisation twice a day, 14 (39%) received lopinavir–ritonavir syrup twice a day, and six (17%) needed oxygen inhalation. …”
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31358por Zhou, Qiang‐hua, Han, Hui, Lu, Jia‐bin, Liu, Ting‐yu, Huang, Kang‐bo, Deng, Chuang‐zhong, Li, Zai‐shang, Chen, Jie‐ping, Yao, Kai, Qin, Zi‐ke, Liu, Zhuo‐wei, Li, Yong‐hong, Guo, Sheng‐jie, Ye, Yun‐lin, Zhou, Fang‐jian, Liu, Ran‐yi“…IDO1 expression was positively correlated with the expression of interferon‐γ (IFNγ, P < 0.001) and immunosuppressive markers (programmed cell death protein 1, cytotoxic T‐lymphocyte‐associated protein 4 and programmed death‐ligand 1 and 2; all P < 0.05), and the infiltration of immune cells (including cytotoxic T lymphocytes, regulatory T lymphocytes, tumor‐associated macrophages, and myeloid‐derived suppressor cells; all P < 0.001) in PSCC tissues. …”
Publicado 2020
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31359“…Both CsAg17 protein and cDNA vaccines increased the proportion of CD3(+)/CD4(+) and CD3(+)/CD8(+) T cells and stimulated the production of Th1 type cytokines such as interleukin (IL)-2, IL-12, and interferon-γ, while maintaining minimum levels of Th2 cytokines. …”
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31360por Yan, Feihu, Li, Entao, Li, Ling, Schiffman, Zachary, Huang, Pei, Zhang, Shengnan, Li, Guohua, Jin, Hongli, Wang, Hualei, Zhang, Xinghai, Gao, Yuwei, Feng, Na, Zhao, Yongkun, Wang, Chengyu, Xia, Xianzhu“…Studies in mice also demonstrated that the Tibet/30 VLPs induced a more robust interleukin 4 and interferon γ response than the Nigeria 75/1 VLPs. Goats and sheep immunized with both VLPs exhibited a robust humoral and cell-mediated immune response. …”
Publicado 2020
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