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31381“…Strong correlations were observed between ACE2 expression levels and multiple immune gene signatures including interferon-stimulated genes and the T cell-inflamed phenotype as well as inverse associations with angiogenesis and transforming growth factor-β signatures. …”
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31382por Riva, Antonio, Gray, Elizabeth H., Azarian, Sarah, Zamalloa, Ane, McPhail, Mark J.W., Vincent, Royce P., Williams, Roger, Chokshi, Shilpa, Patel, Vishal C., Edwards, Lindsey A.“…RESULTS: Faecal (F) IL-1β, interferon gamma, tumour necrosis factor alpha, IL-21, IL-17A/F, and IL-22 were significantly elevated in AD vs. …”
Publicado 2020
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31383por Lu, Mingmin, Tian, Xiaowei, Zhang, Yang, Aimulajiang, Kalibixiati, Wang, Wenjuan, Ehsan, Muhammad, Li, Charles, Yan, Ruofeng, Xu, Lixin, Song, Xiaokai, Li, Xiangrui“…Simultaneously, rHcADRM1 stimuli exerted critical controls on T cell cytokine secretion profiles, predominantly by restraining the secretions of interleukin (IL)-4, IL-10 and interferon-gamma. CONCLUSIONS: Importantly, HcADRM1 protein may have prophylactic potential for anti-H. contortus vaccine development. …”
Publicado 2020
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31384por Ng, Harry Ho Man, Lee, Ren Yuan, Goh, Siting, Tay, Isabel Shu Ying, Lim, Xinru, Lee, Bernett, Chew, Valerie, Li, Huihua, Tan, Benedict, Lim, Sherlly, Lim, Jeffrey Chun Tatt, Au, Bijin, Loh, Josh Jie Hua, Saraf, Sahil, Connolly, John Edward, Loh, Tracy, Leow, Wei Qiang, Lee, Joycelyn Jie Xin, Toh, Han Chong, Malavasi, Fabio, Lee, Ser Yee, Chow, Pierce, Newell, Evan W, Choo, Su Pin, Tai, David, Yeong, Joe, Lim, Tony Kiat Hon“…CD38(hi) macrophages produce more interferon γ (IFN-γ) and related cytokines, which may explain its predictive value when treated with ICB. …”
Publicado 2020
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31385por Liu, Yanhong, Xue, Ge, Li, Shuang, Fu, Yajie, Yin, Jingwen, Zhang, Runxiang, Li, Jianhong“…After 21-day IMCS (at D36), the expression levels of TLR1, TLR15 and TLR21, interleukin (IL)-8, and interferon (IFN)-γ, as well as AvBD8 in CS groups, were lower than those in CC (p < 0.05). …”
Publicado 2020
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31386por Al-Rashed, Fatema, Sindhu, Sardar, Arefanian, Hossein, Al Madhoun, Ashraf, Kochumon, Shihab, Thomas, Reeby, Al-Kandari, Sarah, Alghaith, Abdulwahab, Jacob, Texy, Al-Mulla, Fahd, Ahmad, Rasheed“…Reducing blood glucose as well as glucose fluctuations is critical to the control of T2D and its macro-/microvascular complications. The interferon regulatory factor (IRF)-5 located downstream of the nutrient sensor toll-like receptor (TLR)-4, is emerging as a key metabolic regulator. …”
Publicado 2020
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31387“…The main protective antiviral, anti-inflammatory and mucolytic mechanisms of 1,8-cineole are the induction of interferon regulatory factor 3 (IRF3), the control of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) along with decreasing mucin genes (MUC2, MUC19). …”
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31388por Yu, Xiao, Lakerveld, Anke J., Imholz, Sandra, Hendriks, Marion, ten Brink, Sofie C. A., Mulder, H. Lie, de Haan, Karen, Schepp, Rutger M., Luytjes, Willem, de Jong, Menno D., van Beek, Josine, van Kasteren, Puck B.“…During acute RSV infection, a statistically significant local upregulation of beta interferon (IFN-β), IFN-λ1, IFN-γ, interleukin 1β (IL-1β), tumor necrosis factor alpha (TNF-α), IL-6, IL-10, CXCL8, and CXCL10 was found. …”
Publicado 2020
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31389por Shi, Yulong, Luo, Peng, Wang, Weikang, Horst, Klemens, Bläsius, Felix, Relja, Borna, Xu, Ding, Hildebrand, Frank, Greven, Johannes“…This in vitro study elucidated that M1-EVs from macrophages induced by interferon-γ (IFN-γ) and lipopolysaccharide (LPS) 24 h (M1), but not M0-EVs from untreated macrophages (M0), shifted M0 into M1 phenotype via activating the nuclear factor-κB pathway. …”
Publicado 2020
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31390por Joean, Oana, Thiele, Thea, Schütz, Katharina, Schwerk, Nicolaus, Sedlacek, Ludwig, Kalsdorf, Barbara, Baumann, Ulrich, Stoll, Matthias“…All had a positive Interferon-Gamma-Release Assay (IGRA), in five patients sputum microscopy was positive for acid-fast bacilli (AFB). …”
Publicado 2020
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31391por Wei, Zhenhong, Li, Yuanting, Wei, Chaojun, Li, Yonghong, Xu, Hui, Wu, Yu, Jia, Yanjuan, Guo, Rui, Jia, Jing, Qi, Xiaoming, Li, Zhenhao, Gao, Xiaoling“…Some scientist had focused on a set of cytokines as biomarkers besides interferon- gamma (IFN-γ) to distinguish active TB and LTBI, but with considerable variance of results. …”
Publicado 2020
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31392por El-Bahr, Sabry Mohamed, Shousha, Saad, Albokhadaim, Ibrahim, Shehab, Ahmed, Khattab, Wassem, Ahmed-Farid, Omar, El-Garhy, Osama, Abdelgawad, Abdelrahman, El-Naggar, Mehrez, Moustafa, Mahmoud, Badr, Omnia, Shathele, Mohammad“…In a dose-dependent manner, ZnO-NPs upregulated the mRNA levels of antioxidant enzymes (superoxide dismutase: SOD1; catalase: CAT; glutathione peroxidase-1: GPX 1) and pro-inflammatory cytokines (interferon α: IFN-α; interleukin 6: IL-6) in liver and brain tissues. …”
Publicado 2020
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31393por Bjorvatn, Bjørn, Axelsson, John, Pallesen, Ståle, Waage, Siri, Vedaa, Øystein, Blytt, Kjersti M., Buchvold, Hogne V., Moen, Bente E., Thun, Eirunn“…The following biomarkers were measured: interleukin-1alpha, interleukin-1beta, interleukin-4, interleukin-6, interleukin-8, interleukin-10, interleukin-13, monocyte chemoattractant protein-1, interferon-gamma, and tumor necrosis factor-alpha. Multiple linear regressions with adjustment for age, sex and body mass index (study 1) and ANOVAs with repeated measures (study 2) were conducted. …”
Publicado 2020
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31394por Calles, Antonio, Aparicio, María Inmaculada, Alva, Manuel, Bringas, Marianela, Gutierrez, Natalia, Soto, Javier, Arregui, Marta, Tirado, Victoria Clara, Álvarez, Enrique Luis, del Monte-Millán, María, Massarrah, Tatiana, Galera, Mar, Álvarez, Rosa, Martín, Miguel“…In our series, hospitalization rate was 74%, 39% of patients developed acute respiratory distress syndrome (ARDS), and the case-fatality rate was 35% (8/23). 87% of patients received anti-viral treatment (87% hydroxychloroquine, 74% lopinavir/ritonavir, 13% azithromycin), 43% corticosteroids, 26% interferon-β, 4% tocilizumab, and 82% of hospitalized patients received anticoagulation. …”
Publicado 2020
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31395por Kwon, Riri, Hong, Bong-Ki, Lee, Kang-Gu, Choi, Eunbyeol, Sabbagh, Laurent, Cho, Chul-Soo, Lee, Naeun, Kim, Wan-Uk“…The immune cell subpopulation infiltrated into the tumor mass as well as the expression of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) in T cells was assessed by flow cytometry and/or immunohistochemistry. …”
Publicado 2020
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31396por Xin, Jinge, Zeng, Dong, Wang, Hesong, Sun, Ning, Khalique, Abdul, Zhao, Ying, Wu, Liqian, Pan, Kangcheng, Jing, Bo, Ni, Xueqin“…BS15 treatment exerted significant preventive effects on reversing the gut inflammation induced by excessive fluoride intake by reducing (P < 0.05) the levels of pro-inflammatory cytokines (tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ)) and remarkably increasing (P < 0.05) the level of anti-inflammatory cytokines (IL-10). …”
Publicado 2020
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31397por Song, Ahui, Wang, Jingjing, Tong, Yan, Fang, Junyan, Zhang, Yi, Zhang, Huiping, Ruan, Hongqiang, Wang, Kai, Liu, Yingli“…Furthermore, THP-1 cells (human monocytic cell line) stimulated with LPS/interferon gamma (IFN-γ) produced more anti-inflammatory cytokines after treatment with exosomes derived from BKCa channel-knockdown WJ-MSCs (si-exo). …”
Publicado 2020
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31398por Allain-Maillet, Sophie, Bosseboeuf, Adrien, Mennesson, Nicolas, Bostoën, Mégane, Dufeu, Laura, Choi, Eun Ho, Cleyrat, Cédric, Mansier, Olivier, Lippert, Eric, Le Bris, Yannick, Gombert, Jean-Marc, Girodon, François, Pettazzoni, Magali, Bigot-Corbel, Edith, Hermouet, Sylvie“…Here we analysed 42 inflammatory cytokines and report that in patients as well as in UT-7 cell lines, interleukin-1β and interferon-induced protein 10 (IP-10) were the main inflammatory molecules found to be induced by JAK2V617F, the most frequent driving mutation in MPNs. …”
Publicado 2020
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31399por Huang, Chen, Wu, Lili, Liu, Ruixia, Li, Weijing, Li, Zheng, Li, Jianqiang, Liu, Lihong, Shan, Baoen“…Interleukin-1β (IL-1β), interferon-γ (IFN-γ), interleukin-10 (IL-10), and interleukin-17A (IL-17A) appeared to be associated with the occurrence of CRS and CRES. …”
Publicado 2020
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31400IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice“…Furthermore, IL-18BP treatment inhibited the IL-18 downstream target interferon (IFN)-γ expression in mouse BM, decreased reactive oxygen species (ROS) level in the irradiated mouse heart tissues, attenuated the stress responsive factor GDF-15 (growth differentiation factor-15) and increased the intestine protector citrulline level in total body irradiated mouse serum, implicating that IL-18BP may protect multiple organs from radiation-induced inflammation and oxidative stress. …”
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