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31621por Chiu, Chun-Hsiang, Chang, Yu-Hsiu, Tao, Chi-Wei, Chang, Feng-Yee, Chiu, Kuo-Chou, Chang, Tien-Wei, Yen, Li-Chen“…Besides, the numbers of gamma interferon (IFN-γ)-secreting T cells induced by 2× MVC/Mod were also elevated 3.5-fold and 3.7- to 4.3-fold for the wild type and Delta variant. …”
Publicado 2022
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31622por Tesfaye, Fregenet, Sturegård, Erik, Walles, John, Bekele, Bayissa, Bobosha, Kidist, Björkman, Per, Jansson, Marianne“…Twenty-two TB+ women and 10 TB− women, defined according to Mtb-stimulated interferon-γ levels (≥0.35 and <0.20 IU/mL, respectively, in the Quantiferon-TB Gold-Plus assay), were included in the study. …”
Publicado 2022
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31623por Soliman, Soliman M., Aljahdali, Nesreen H., Majrashi, Kamlah Ali, El-Gameel, Sohila M., Ismael, Elshaimaa, Salem, Heba M., Mahmoud, Mahmoud A., Albaqami, Najah M., Mahjoub, Haifaa A., El-Saadony, Mohamed T., Attia, Marwa M.“…The cell-mediated immunity against the C. cerebralis cyst was also assessed via quantitative Real Time—Polymerase Chain Reaction (qRT-PCR) to show alterations in mRNA expression of the Tumor Necrosis Factor-alpha (TNF-α) and gamma Interferon (IFN-γ) cytokines qRT-PCR. In histopathological sections, cerebral tissue showed an areolar cyst wall with many protoscolices attached to the tissue. …”
Publicado 2022
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31624por Drees, Marci, Gireesh, Lija, Briody, Carol, Miller, Charlotte, Hanlin, Emily, Li, Ruoran, Wilson, William, Schwartz, Noah, Benowitz, Isaac, Glowicz, Janet, Mase, Tabe“…Employee health services (EHS) instituted a dedicated phlebotomy station to provide interferon-γ release assay (IGRA) testing for HCP at ≥8 weeks after last known exposure. …”
Publicado 2022
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31625por Elizalde, Patricia, Roldan Deamicis, Agustina, Oakley, Robert, Madera, Santiago, Cordo Russo, Rosalía, Schillaci, Roxana, Fresno, Cristóbal, Cidlowski, John, Proietti, Cecilia“…By using the Tumor Immune Estimation Resource (TIMER) we found a significant association of the expression of the gene signature and the abundance of tumor immune infiltrates, in accordance with the involvement of the gene signature in the immune response and interferon pathways. We have validated the regulation of the gene signature in MDA-MB-453 cells and found that in the presence of DHT, eviction of NErbB-2 significantly induces the mRNA expression of the genes CXCL10, HLA-A, NMI, STAT1 and TAP1, members of said gene signature. …”
Publicado 2022
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31626por Khan, Muhammad, Lin, Jie, Wang, Baiyao, Chen, Chengcong, Huang, Zhong, Tian, Yunhong, Yuan, Yawei, Bu, Junguo“…Para-inflammation and type-II interferon pathways were activated in NRGPI-high patients with an increased infiltration of Tregs and M2 macrophage indicating an exhausted immune phenotype of the tumor microenvironment. …”
Publicado 2022
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31627por Xu, Guoxin, Gong, Yanping, Lu, Fenying, Wang, Bin, Yang, Zaixing, Chen, Long, Min, Jingyu, Cheng, Cuie, Jiang, Tingwang“…Also, we determined the levels of M2 subtype anti-mitochondrial antibody (AMA-M2), interferon-gamma (IFN-γ), and tumor-necrosis factor alpha (TNFα) in serum with ELISA assay. …”
Publicado 2022
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31628por Stachowicz, Aneta, Pandey, Rakhi, Sundararaman, Niveda, Venkatraman, Vidya, Van Eyk, Jennifer E., Fert-Bober, Justyna“…Silencing PAD2 confirmed the activation of M2 macrophages by increasing the antiviral innate immune response and interferon signalling. A total of 192 novel citrullination sites associated with inflammation, cell death and DNA/RNA processing pathways were identified in M1 and M2 macrophages. …”
Publicado 2022
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31629por Gulmez, Ruveyda, Ozbey, Dogukan, Agbas, Ayse, Aksu, Bagdagul, Yildiz, Nurdan, Uckardes, Diana, Saygili, Seha, Yilmaz, Esra Karabag, Yildirim, Zeynep Yuruk, Tasdemir, Mehmet, Kiykim, Ayca, Cokugras, Haluk, Canpolat, Nur, Nayir, Ahmet, Kocazeybek, Bekir, Caliskan, Salim“…Humoral (anti-SARS-CoV2 IgG, neutralizing Ab (nAb)) and cellular (interferon-gamma release assay (IGRA)) immune responses were assessed at least one month after two doses of BNT162b2 mRNA vaccine. …”
Publicado 2022
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31630por Schwarz, Sandra, Schmitz, Johanna, Löffler, Markus W, Ghosh, Michael, Rammensee, Hans-Georg, Olshvang, Evgenia, Markel, Marvin, Mockel-Tenbrinck, Nadine, Dzionek, Andrzej, Krake, Susann, Arslan, Basak, Kampe, Kapil Dev, Wendt, Anne, Bauer, Peter, Mullins, Christina S, Schlosser, Andreas, Linnebacher, Michael“…In addition, B-lymphoblastoid cells (B-LCL) were generated and used as antigen-presenting cells. pTc and TiTc were stimulated twice for 7 days using peptide pool-loaded B-LCL. Subsequently, interferon gamma (IFNγ) release was quantified by ELISpot. …”
Publicado 2022
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31631por Tanagala, Kranthi Kiran Kishore, Morin-Baxter, Joshua, Carvajal, Richard, Cheema, Maryum, Dubey, Sunil, Nakagawa, Hiroshi, Yoon, Angela, Cheng, Yi-Shing L, Taylor, Alison, Nickerson, Jeffrey, Mintz, Akiva, Momen-Heravi, Fatemeh“…Tumors with high SP140 expression showed enrichment of inflammatory response and interferon-gamma (IFN-γ) pathways in both pan-cancer analysis and HNSCC-specific analysis. …”
Publicado 2022
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31632por Marco, Iannetta, Spalliera, Ilaria, Mallegni, Flavia, Mercante, Lisa, Imeneo, Alessandra, Crea, Angela, Lorenzo, Andrea Di, Campogiani, Laura, Malagnino, Vincenzo, Angelis, Gottardo De, Cerretti, Raffaella, Andreoni, Massimo, Sarmati, Loredana“…T-cell responses were assessed with an Interferon (IFN)-γ release assay (IGRA), after overnight stimulation of heparin whole blood with pools of lyophilized peptides, covering the immunodominant sequence of the Spike (S) protein. …”
Publicado 2022
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31633“…LTBI cascade among non-US-born primary care patients [Figure: see text] IGRA: interferon-gamma release assay; TST: tuberculin skin test. …”
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31634por Lee, Subum, Seo, Ye-Jin, Choi, Je-Yong, Che, Xiangguo, Kim, Hyun-Ju, Eum, Seok-Yong, Hong, Min-Sun, Lee, Sun-Kyoung, Cho, Dae-Chul“…Selected chemokines (interleukin [IL]-8, interferon γ-induced protein 10 kDa [IP-10], monocyte chemoattractant protein [MCP]-1, and regulated upon activation, normal T cell expressed and presumably secreted [RANTES]) and osteoblast proliferation (alkaline phosphatase [ALP] and alizarin red S [ARS] staining) were measured. …”
Publicado 2022
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31635por Vaxevanis, Christoforos K., Bauer, Marcus, Subbarayan, Karthikeyan, Friedrich, Michael, Massa, Chiara, Biehl, Katharina, Al-Ali, Haifa Kathrin, Wickenhauser, Claudia, Seliger, Barbara“…Abbreviations: Ab, antibody; alloSCT, allogenic stem cell transplant; AML, acute myeloid leukemia; BGN, biglycan; BM, bone marrow; BMB, bone marrow biopsy; casp1, caspase 1; CTLA-4, cytotoxic T lymphocyte-associated protein 4; DAMP, danger-associated molecular pattern; ECM, extracellular matrix; FCS, fetal calf serum; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HD, healthy donor; HSPC, hematopoietic stem and progenitor cell; HSC, hematopoietic stem cell; IFN, interferon; IHC, immunohistochemistry; IL, interleukin; MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm; MSI, multispectral imaging; NGS, next-generation sequencing; NLRP3, NLR family pyrin domain containing 3; OS, overall survival; PBMC, peripheral blood mononuclear cell; PD-1, programmed cell death protein 1; PD-L1, programmed death-ligand 1, PFS, progression-free survival; PRR, pattern recognition receptor; SC, stem cell; SLRP, small leucine-rich proteoglycan; TGF, transforming growth factor; TIRAP, toll/interleukin 1 receptor domain-containing adapter protein; TLR, toll-like receptor; Treg, regulatory T cell.…”
Publicado 2022
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31636por Huang, Huaying, Jin, Ke, Ouyang, Ke, Jiang, Zhengyi, Yang, Zhan, Hu, Nannan, Dai, Yan, Zhang, Yaqin, Zhang, Qian, Han, Ying, Zhao, Jie, Lin, Hong, Wang, Chunhui, Wang, Chunyan, Sun, Xuewei, Lu, Dafeng, Zhu, Jin, Li, Jun“…Effects of CyPA inhibitor Cyclosporine A (CsA) on cytokines and SFTSV replication in THP-1 cells was also detected. 8-week-old Interferon-α/β Receptor (IFNAR) knockout (IFNAR-/-) C57BL/6 mice were divided into mock group, 10(6)TCID(50) SFTSV (Untreated) group and 10(6)TCID(50) SFTSV+CsA (CsA-treated) group. …”
Publicado 2022
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31637por Huang, Bin, Gui, Mengxuan, Ni, Zhuona, He, Yanbin, Zhao, Jinyan, Peng, Jun, Lin, Jiumao“…We found that 5-FU, CPT-11, and l-OHP caused intestinal injury, inflammatory cytokine (gamma interferon [IFN-γ], tumor necrosis factor alpha [TNF-α], interleukin-1β [IL-1β], and IL-6) secretion, and gut microbiota disorder. …”
Publicado 2022
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31638Infants with Down syndrome and congenital heart disease have altered peri-operative immune responsespor Zakharchenko, Lyudmyla, EL-Khuffash, Afif, Hurley, Tim, Kelly, Lynne, Melo, Ashanti, Padden, Maureen, Franklin, Orla, Molloy, Eleanor J.“…METHODS: Infants with DS/CHD, infants without DS but with CHD (CHD only) and healthy infants were prospectively recruited and serial serum cytokines evaluated peri-operatively using multiplex ELISA: tumour necrosis factor (TNF)-α and TNF-β; interferon (IFN)-γ, interleukin (IL)-1α, IL-2, IL-6, IL-8, IL-18, IL-1β, IL-10, and IL-1ra; vascular endothelial growth factor (VEGF); granulocyte macrophage colony-stimulating factor (GM-CSF); and erythropoietin (EPO). …”
Publicado 2022
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31639por Küçükköse, Emre, Heesters, Balthasar A, Villaudy, Julien, Verheem, André, Cercel, Madalina, van Hal, Susan, Boj, Sylvia F, Borel Rinkes, Inne H M, Punt, Cornelis J A, Roodhart, Jeanine M L, Laoukili, Jamila, Koopman, Miriam, Spits, Hergen, Kranenburg, Onno“…Therapy efficacy correlated with the formation of tertiary lymphoid structures (TLS)—containing B cells and juxtaposed T cells—and with expression of an interferon-γ signature together with the B cell chemoattractant CXCL13. …”
Publicado 2022
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31640“…Preoperative interleukin (IL)-4, IL-6, IL-10, tumor necrosis factor-α, interferon-γ, and PCT levels were higher in the infection group than in the non-infection group (P < 0.05), and there were no significant differences in the IL-2 Levels between the two groups (P > 0.05). …”
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