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31781por Barrachina, Laura, Remacha, Ana Rosa, Romero, Antonio, Vitoria, Arantza, Albareda, Jorge, Prades, Marta, Roca, Mercedes, Zaragoza, Pilar, Vázquez, Francisco José, Rodellar, Clementina“…BACKGROUND: This study aimed at assessing the effectiveness and safety of repeated administrations of allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α and interferon-γ in an equine model of chemically-induced osteoarthritis. …”
Publicado 2018
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31782por Zhang, Yi, Guo, Hui, Cheng, Brian Chi-Yan, Su, Tao, Fu, Xiu-Qiong, Li, Ting, Zhu, Pei-Li, Tse, Kai-Wing, Pan, Si-Yuan, Yu, Zhi-Ling“…Phosphorylation and nuclear protein levels of transcription factors (activator protein-1 [AP-1], NF-κB, interferon regulatory factor 3 [IRF3]) were decreased by DCEO. …”
Publicado 2018
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31783por Frasca, Loredana, Palazzo, Raffaella, Chimenti, Maria S., Alivernini, Stefano, Tolusso, Barbara, Bui, Laura, Botti, Elisabetta, Giunta, Alessandro, Bianchi, Luca, Petricca, Luca, Auteri, Simone E., Spadaro, Francesca, Fonti, Giulia L., Falchi, Mario, Evangelista, Antonella, Marinari, Barbara, Pietraforte, Immacolata, Spinelli, Francesca R., Colasanti, Tania, Alessandri, Cristiano, Conti, Fabrizio, Gremese, Elisa, Costanzo, Antonio, Valesini, Guido, Perricone, Roberto, Lande, Roberto“…LL37 binds nucleic acids and stimulates plasmacytoid/myeloid dendritic cells (pDC, mDCs) to secrete type I interferon (IFN-I) and pro-inflammatory factors. LL37 becomes an autoantigen for psoriatic Th1-Th17/CD8 T cells. …”
Publicado 2018
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31784por Wang, Lei, Ni, Ming, Hückelhoven-Krauss, Angela, Sellner, Leopold, Hoffmann, Jean-Marc, Neuber, Brigitte, Luft, Thomas, Hegenbart, Ute, Schönland, Stefan, Kleist, Christian, Sill, Martin, Chen, Bao-an, Wuchter, Patrick, Eckstein, Volker, Krüger, William, Hilgendorf, Inken, Yerushalmi, Ronit, Nagler, Arnon, Müller-Tidow, Carsten, Ho, Anthony D., Dreger, Peter, Schmitt, Michael, Schmitt, Anita“…A comprehensive analysis of effector and regulatory cells in patients under ECP therapy included multi-parametric flow cytometry and tetramer staining, Luminex(TM)-based cytokine, interferon-γ enzyme-linked immunospot, and chromium-51 release assays. …”
Publicado 2018
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31785“…METHODS: CD4 T cells in 98 blood samples of patients with RA (n = 78) or SpA (n = 20) were quantified by flow cytometry after stimulation with VZV antigen and the polyclonal stimulus Staphylococcus aureus enterotoxin B (SEB), and they were characterized for expression of cytokines (interferon-γ, tumor necrosis factor [TNF]-α, interleukin [IL]-2) and markers for activation (CD69), differentiation (CD127), or functional anergy programmed death 1 molecule [PD-1], cytotoxic T-lymphocyte antigen 4 [CTLA-4]. …”
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31786por Kumarasamy, Nagalingeswaran, Poongulali, Selvamuthu, Beulah, Faith Esther, Akite, Elaine Jacqueline, Ayuk, Leo Njock, Bollaerts, Anne, Demoitié, Marie-Ange, Jongert, Erik, Ofori-Anyinam, Opokua, Van Der Meeren, Olivier“…Latent TB infection was assessed at screening using an interferon-gamma (IFN-γ) release assay (IGRA). Safety and immunogenicity results up to Y1 post-vaccination were reported elsewhere. …”
Publicado 2018
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31787por Martins, T., Sponchiado, M., Ojeda-Rojas, O. A., Gonella-Diaza, A. M., Batista, E. O. S., Cardoso, B. O., Rocha, C. C., Basso, A. C., Binelli, M.“…Conceptus signaling was monitored by transcript abundance of interferon-stimulated gene 15 (ISG15) in peripheral blood mononuclear cells isolated on D14, D16, D18 and D20. …”
Publicado 2018
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31788por Watanabe, M., Kumagai-Braesch, Makiko, Yao, M., Thunberg, S., Berglund, D., Sellberg, F., Jorns, C., Enoksson, S. Lind, Henriksson, J., Lundgren, T., Uhlin, M., Berglund, E., Ericzon, B.-G.“…After 14 days of coculture, the frequencies of CD4(+) T cells, CD8(+) T cells, and natural killer cells as well as interferon gamma (IFN-γ) production in the 2D10.4/IT2.2- and belatacept-treated groups were lower than those in the control group. …”
Publicado 2018
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31789por Spadaro, Savino, Park, Mirae, Turrini, Cecilia, Tunstall, Tanushree, Thwaites, Ryan, Mauri, Tommaso, Ragazzi, Riccardo, Ruggeri, Paolo, Hansel, Trevor T., Caramori, Gaetano, Volta, Carlo Alberto“…Biomarkers of particular interest have included interleukins (IL-6 and IL-8), interferon gamma (IFN-γ), surfactant proteins (SPD and SPB), von Willebrand factor antigen, angiopoietin 1/2 and plasminogen activator inhibitor-1 (PAI-1). …”
Publicado 2019
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31790por Gunawardana, Thushari, Ahmed, Khawaja Ashfaque, Goonewardene, Kalhari, Popowich, Shelly, Kurukulasuriya, Shanika, Karunarathna, Ruwani, Gupta, Ashish, Lockerbie, Betty, Foldvari, Marianna, Tikoo, Suresh K., Willson, Philip, Gomis, Susantha“…Multiplex gene analysis (interleukin (IL)-1, IL-4, IL-6, IL-10, IL-18, interferon (IFN)-γ, IFN-α, and lipopolysaccharide induced tumor necrosis factor (LITAF), revealed a significantly higher expression of pro-inflammatory cytokines following CpG-ODN treatment compared to the saline controls. …”
Publicado 2019
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31791por Azzam, Mahmoud Mostafa, JIANG, Shou-qun, CHEN, Jia-li, LIN, Xia-jing, GOU, Zhong-yong, FAN, Qiu-li, WANG, Yi-bing, LI, Long, JIANG, Zong-yong“…Supplemental SI at 20 mg/kg decreased (p < 0.05) the viral protein 5 (VP5) mRNA expression at 3 dpi and 7 dpi. The level of interferon gamma (IFNγ) was elevated (p < 0.05) in the infected group at 3 dpi and 7 dpi as compared with the control group, while its level was decreased (p < 0.05) by supplemental 10 mg/kg SI at 3 dpi. …”
Publicado 2019
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31792por Eisenhut, Michael“…The infection rate of mice vaccinated with BCG and exposed after 6 weeks to ULD of MTB and unvaccinated mice are compared via cultures of lung homogenates and interferon (IFN) gamma release assay. If a reduced infection rate by BCG immunization is confirmed, the experiment is repeated by giving BCG combined simultaneously or in time sequence with the enhancers of innate immunity murabutide or beta-glycan. …”
Publicado 2019
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31793por Khatlab, Angélica de Souza, Del Vesco, Ana Paula, de Oliveira Neto, Adhemar Rodrigues, Fernandes, Roberta Pereira Miranda, Gasparino, Eliane“…Eimeria spp. challenge suppressed neutral amino acid transporter 1 (B(0)AT1), peptide transporter 1 (PEPT1), toll-like receptor 5 (TLR5), interleukin 2 (IL2), and occludin (OCLN) gene expression and enhanced cationic amino acid transporter 1 (CAT-1) and interferon gamma (IFNG) gene expression. The highest PEPT1 expression level was observed in broilers fed the dl-MMet diet, and the lowest TLR5 expression level was found in broilers fed the NS diet. …”
Publicado 2019
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31794por Mavi, Sara Ayazian, Modarressi, Mohammad Hossein, Mohebali, Mehdi, Shojaee, Saeedeh, Zeraati, Hojjat, Teimouri, Aref, Keshavarz, Hossein“…Enzyme-linked immunosorbent assay (ELISA) was used to assess total IgG, IgG1 and IgG2a antibodies and gamma interferon (IFN-γ) and interleukin-10 (IL-10) cytokines in mice sera. …”
Publicado 2019
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31795por Essien-Baidoo, Samuel, Obiri-Yeboah, Dorcas, Opoku, Yeboah Kwaku, Ayamga, Elvis, Hodi Zie, Kevin, Attoh, Daniel, Obboh, Evans, Hayfron Benjamin, Anna, Afrifa, Justice“…RESULTS: The mean age of the participants was (45.54 ± 0.7846) years with a greater proportion (84.5%) between 31 and 60 years. The mean interferon-gamma (INF-γ), interleukin- (IL-) 10, interleukin-12, and interleukin-17 were estimated to be 349.9 ± 8.391 pg/ml, 19.32 ± 0.4593 pg/ml, 19.23 ± 0.3960 pg/ml, and 24.6 ± 0.6207 pg/ml, respectively. …”
Publicado 2019
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31796por Elbaz-Hayoun, Sarah, Rinsky, Batya, Hagbi-Levi, Shira, Grunin, Michelle, Chowers, Itay“…The compounds were added to the culture medium of M1 (interferon-gamma [IFN-Ɣ] and lipopolysaccharide [LPS]) and M2a (interleukin-13 [IL-13] and IL-4) hMDMs from patients with AMD (n=7 and n=8, respectively). …”
Publicado 2019
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31797por Wong, Chee Wai, Cheung, Ning, Ho, Candice, Barathi, Veluchamy, Storm, Gert, Wong, Tina T.“…Vitreous concentrations of interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 1 beta (IL-1 β), tumor necrosis factor beta (TNF-β), granulocyte macrophage colony stimulating factor (GM-CSF), interferon gamma (IFN-γ), C reactive protein; (CRP), placental growth factor (PlGF), platelet derived growth factor BB (PDGF-BB), vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang-2) at weeks 2, 3 and 4 were compared to baseline and correlations between the cytokines with PVR severity were assessed. …”
Publicado 2019
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31798por Luan, Junjun, Fu, Jingqi, Chen, Chengjie, Jiao, Congcong, Kong, Weiwei, Zhang, Yixiao, Chang, Qing, Wang, Yanqiu, Li, Detian, Illei, Gabor G., Kopp, Jeffrey B., Pi, Jingbo, Zhou, Hua“…Renal pro-inflammatory cytokines (interferon-γ, interleukin-6, and tumor necrosis factor-α) and macrophages were also decreased. …”
Publicado 2019
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31799por Mozhgani, Sayed-Hamidreza, Piran, Mehran, Zarei-Ghobadi, Mohadeseh, Jafari, Mohieddin, Jazayeri, Seyed-Mohammad, Mokhtari-Azad, Talat, Teymoori-Rad, Majid, Valizadeh, Narges, Farajifard, Hamid, Mirzaie, Mehdi, Khamseh, Azam, Rafatpanah, Houshang, Rezaee, Seyed-Abdolrahim, Norouzi, Mehdi“…Biological network analyses indicated the involvement of hub genes in many vital pathways like JAK-STAT signaling pathway, interferon, Interleukins, and immune pathways in the normal vs. …”
Publicado 2019
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31800por Tsertsvadze, Tengiz, Gamkrelidze, Amiran, Nasrullah, Muazzam, Sharvadze, Lali, Morgan, Juliette, Shadaker, Shaun, Gvinjilia, Lia, Butsashvili, Maia, Metreveli, David, Kerashvili, Vakhtang, Ezugbaia, Marina, Chkhartishvili, Nikoloz, Abutidze, Akaki, Kvaratskhelia, Valeri, Averhoff, Francisco“…Initial treatment consisted of SOF plus ribavirin (RBV) with or without pegylated interferon (INF). Sustained virologic response (SVR) was defined as undetectable HCV RNA at least 12 weeks after the end of treatment. …”
Publicado 2020
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