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31981por Zhang, Hai-Bin, Sun, Zhuo-Kai, Zhong, Fang-Min, Yao, Fang-Yi, Liu, Jing, Zhang, Jing, Zhang, Nan, Lin, Jin, Li, Shu-Qi, Li, Mei-Yong, Jiang, Jun-Yao, Cheng, Ying, Xu, Shuai, Cheng, Xue-Xin, Huang, Bo, Wang, Xiao-Zhong“…Immune functions, such as inflammation promotion, para-inflammation, and type I/II interferon responses, were also significantly activated. …”
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31982por Nam, Minjeong, Yun, Seung Gyu, Kim, Sang-wook, Kim, Chris Gunwoo, Cha, Jae Hyun, Lee, Cheonghwa, Kang, Seunghyuk, Park, Seul Gi, Kim, Sun Bean, Lee, Ki-Byung, Chung, You-Seung, Nam, Myung-Hyun, Lee, Chang Kyu, Cho, Yunjung“…At T(1), the levels of the receptor-binding domain antibodies (RBD Ab) and neutralizing antibodies (NAb) decreased with aging, but interferon gamma release (IGR) levels increased. The RBD Ab, NAb, and IGR levels were higher in females than in males at T(1) and T(2). …”
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31983por Wang, Huan, Shu, Jun, Zhang, Chengfei, Wang, Yang, Shi, Rongxing, Yang, Fan, Tang, Xuezhang“…The overexpression of miR-150-3p could significantly reduce the concentrations of pro-inflammatory cytokines in the cell culture medium and the expression of the miR-150-3p target T cell receptor-interacting molecule 14 (Trim14), as well as the innate immune-related factors, including nuclear factor kappa B (NF-κB) and interferon-β (IFN-β). Similarly to the in vitro findings, the miR-150-3p level in the serum EVs was significantly upregulated among the EV-treated rats. …”
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31984por Yang, Penghui, Yang, Hongmei, Zhou, Hengli, Li, Qiuyue, Wei, Sufen, Wang, Qi, Yan, Yan, Liu, Yongqiang, Pan, Huafeng, Li, Siyi“…Expression of the T helper 1 (Th1) cell markers CD4(+) and interferon-gamma (INF-γ) were tested using immunohistochemistry (IHC). …”
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31985por Konlaan, Yatik, Asamoah Sakyi, Samuel, Kumi Asare, Kwame, Amoah Barnie, Prince, Opoku, Stephen, Nakotey, Gideon Kwesi, Victor Nuvor, Samuel, Amoani, Benjamin“…Their plasma cytokine levels of interleukin (IL)-1β, IL-6, IL-10, IL-17, tumour necrosis factor-alpha (TNF-α) and interferon gamma (IFN-γ) were analysed using ELISA. …”
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31986por Church, Candice, Pulliam, Thomas, Longino, Natalie, Park, Song Y, Smythe, Kimberly S, Makarov, Vladimir, Riaz, Nadeem, Jing, Lichen, Amezquita, Robert, Campbell, Jean S, Gottardo, Raphael, Pierce, Robert H, Choi, Jaehyuk, Chan, Timothy A, Koelle, David M, Nghiem, Paul“…Characterization of peripheral blood neoantigen T cell responses was evaluated via interferon-gamma (IFNγ) ELISpot, flow cytometry and single-cell RNA sequencing. …”
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31987“…The ability of Pos3Aa-p53 crystals to remodel tumor microenvironment was investigated by examining the markers of immunogenic cell death (ICD) and the expression of PD-L1, indoleamine 2,3-dioxygenase 1, tryptophan 2,3-dioxygenase 2 and type I interferon (IFN). Finally, both unilateral and bilateral 4T1 tumor mouse models were utilized to assess the efficacy of Pos3Aa-p53 crystal-mediated p53 restoration in enhancing the antitumor activity of ICIs. …”
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31988por Wang, Yulian, Huang, Lisi, Huang, Tian, Geng, Suxia, Chen, Xiaomei, Huang, Xin, Lai, Peilong, Du, Xin, Weng, Jianyu“…In addition, the secretion of proinflammatory interferon- γ (IFN-γ) cytokine in the supplement of cellular culture was increased (4,898.58 ± 235.82 vs. 4,347.87 ± 220.02 pg/ml, p = 0.042) in the mice model of the Scl-cGVHD group, but anti-inflammatory interleukin (IL)-10 decreased (7,636.57 ± 608.05 vs. 9,563.56 ± 603.34 pg/ml, p = 0.018). …”
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31989“…These results suggest that the NV protein is an essential component in the inhibition of host type-I interferon (IFN) and the induction of viral replication. …”
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31990por Mishra, Neha, Aden, Konrad, Blase, Johanna I., Baran, Nathan, Bordoni, Dora, Tran, Florian, Conrad, Claudio, Avalos, Diana, Jaeckel, Charlot, Scherer, Michael, Sørensen, Signe B., Overgaard, Silja H., Schulte, Berenice, Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul A., Schultze, Joachim L., Walter, Jörn, Andersen, Vibeke, Dermitzakis, Emmanouil T., Schreiber, Stefan, Rosenstiel, Philip“…These modules reflected processes such as interferon signaling, erythropoiesis, and platelet aggregation. …”
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31991por Hube, Bernhard“…Pekmezovic et al. (2021) Candida pathogens induce protective mitochondria-associated type I interferon signalling and a damage-driven response in vaginal epithelial cells. …”
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31992por Oliver, Liliana, Alvarez, Rydell, Diaz, Raquel, Valdés, Anet, Colligan, Sean H, Nemeth, Michael J, Twum, Danielle Y F, Fernández, Audry, Fernández-Medina, Olivia, Carlson, Louise M, Yu, Han, Eng, Kevin H, Hensen, Mary L, Rábade-Chediak, Maura L, Fernández, Luis Enrique, Lee, Kelvin P, Perez, Leslie, Muhitch, Jason B, Mesa, Circe, Abrams, Scott I“…RESULTS: We demonstrated that VSSP diminished PMN-MDSCs by shunting granulocyte-monocyte progenitor differentiation toward monocytes/macrophages and DCs with heightened expression of the myeloid-dependent transcription factors interferon regulatory factor-8 and PU.1. This skewing was at the expense of expansion of granulocytic progenitors and rendered the remaining MDSCs less suppressive. …”
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31993por Duan, Cuicui, Ma, Lin, Yu, Jie, Sun, Yixue, Liu, Lifan, Ma, Fumin, Li, Xiaolei, Li, Dan“…Furthermore, OVA-specific immunoglobulin E (IgE), OVA-specific-IgG1, and plasma histamine levels were declined in mice treated with L. plantarum JC7 than in OVA-sensitised mice. In addition, interferon-γ (IFN-γ) and interleukin 10 (IL-10) levels were significantly increased, while IL-4 and IL-17A levels were clearly decreased in mice that had undergone oral administration of L. plantarum JC7, compared with OVA-sensitised mice. …”
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31994por Denicolò, Sara, Laydevant, Sophie, Fink, Julia, Geiger, Christoph, Pizzini, Alex, Sarcletti, Mario, Zschocke, Johannes, Bellmann-Weiler, Rosa, Weiss, Günter, Tancevski, Ivan“…The patient received antimycobacterial treatment combined with subcutaneous type I interferon, which eventually led to a gradual improvement over the next months. …”
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31995por Cao, Cunwei“…Our cohort studies identified three major immunodeficiencies in non-HIV patients with talaromycosis: (1) 85.9% anti-interferon-γ autoantibodies, (2) primary immunodeficiency disorders, and (3) tumors. …”
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31996por Alidjinou, Enagnon Kazali, Demaret, Julie, Corroyer-Simovic, Bénédicte, Vuotto, Fanny, Miczek, Sophie, Labreuche, Julien, Goffard, Anne, Trauet, Jacques, Lupau, Daniela, Dendooven, Arnaud, Huvent-Grelle, Dominique, Podvin, Juliette, Dreuil, Daniel, Faure, Karine, Deplanque, Dominique, Bocket, Laurence, Duhamel, Alain, Sobaszek, Annie, Hober, Didier, Hisbergues, Michael, Puisieux, Francois, Autran, Brigitte, Yazdanpanah, Yazdan, Labalette, Myriam, Lefèvre, Guillaume“…Anti–SARS coronavirus 2 IgG levels and cellular response (through interferon γ ELISpot assay) were evaluated in all participants, and neutralizing antibodies against Delta, BA.1, and BA.2 were evaluated in participants with at least one follow-up visit 1 or 3 months after the administration of the booster dose. …”
Publicado 2023
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31997por Kim, Chan, Yang, Hannah, Kim, Ilhwan, Kang, Beodeul, Kim, Hyeyeong, Kim, Hyunho, Lee, Won Suk, Jung, Sanghoon, Lim, Ho Yeong, Cheon, Jaekyung, Chon, Hong Jae“…Compared with patients with low ADA levels, patients with high ADA levels exhibited reduced serum atezolizumab concentrations, impaired CD8-positive T-cell proliferation, and had decreased interferon-γ and tumor necrosis factor-α from CD8-positive T cells compared with patients with low ADA levels. …”
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31998“…Long interspersed element type 1 (LINE-1) is the only known type of retroelement that can replicate autonomously, and its retrotransposition activity can trigger interferon (IFN) production. IFN production suppresses the infectivity of exogenous viruses, such as human immunodeficiency virus (HIV). …”
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31999por Chen, Jia, Xing, MingYou, Xu, Dong, Xie, NaNa, Zhang, WenCong, Ruan, QiuRong, Song, JianXin“…The etiological diagnostic models included the following factors: multisite metabolic characteristics, blood cell counts, inflammatory indicators (erythrocyte sedimentation rate, C-reactive protein, serum ferritin, and lactate dehydrogenase), immunological indicators (interferon gamma release assay, antinuclear antibody, and anti-neutrophil cytoplasm antibody), specific signs (weight loss, rash, and splenomegaly), and age. …”
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32000por Heath, Paul T, Galiza, Eva P, Baxter, David Neil, Boffito, Marta, Browne, Duncan, Burns, Fiona, Chadwick, David R, Clark, Rebecca, Cosgrove, Catherine A, Galloway, James, Goodman, Anna L, Heer, Amardeep, Higham, Andrew, Iyengar, Shalini, Jeanes, Christopher, Kalra, Philip A, Kyriakidou, Christina, Bradley, Judy M, Munthali, Chigomezgo, Minassian, Angela M, McGill, Fiona, Moore, Patrick, Munsoor, Imrozia, Nicholls, Helen, Osanlou, Orod, Packham, Jonathan, Pretswell, Carol H, San Francisco Ramos, Alberto, Saralaya, Dinesh, Sheridan, Ray P, Smith, Richard, Soiza, Roy L, Swift, Pauline A, Thomson, Emma C, Turner, Jeremy, Viljoen, Marianne Elizabeth, Fries, Louis, Cho, Iksung, McKnight, Irene, Glenn, Greg, Rivers, E Joy, Robertson, Andreana, Alves, Katia, Smith, Kathy, Toback, Seth“…High anti-S and neutralization responses to vaccination were evident, together with S-protein–specific induction of interferon-γ secretion in peripheral blood T cells. …”
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