-
32441por Grine, Lynda, Steeland, Sophie, Van Ryckeghem, Sara, Ballegeer, Marlies, Lienenklaus, Stefan, Weiss, Siegfried, Sanders, Niek N., Vandenbroucke, Roosmarijn E., Libert, Claude“…To investigate the production of type I interferons in response to imiquimod-containing Aldara cream, IFNβ-luciferase reporter mice were imaged in vivo and ex vivo. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32442“…Diese verfügen über Proteine, die als Rezeptoren (beispielsweise toll-like-Rezeptoren, Komplementrezeptoren) für bestimmte Erregerstrukturen und für die löslichen Produkte des unspezifischen Immunsystems (Akutphaseproteine, die Faktoren des Komplementsystems, Cytokine, Chemokine und Interferone) dienen. Auf die Wirkung und Funktion der Cytokine, Chemokine und Interferone wird in ▸ Kapitel 8 gesondert eingegangen.…”
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32443“…Many studies have reported that the combination of interferons and NRTI causes the loss of hepatitis B surface antigen (HBsAg), which is suggestive of seroconversion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32444“…Accelerated prion infections have been seen in interleukin-10 knockout mice, and type 1 interferons have been found to be protective against these diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32445“…Amongst the results, we identified five popular targets of use: IL6 and IL1 inhibitors, interferons, mesenchymal stem cells treatment, and anti-spike antibodies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32446por Tanaka, Mizuki, Hasegawa, Shiori, Nakao, Satoshi, Shimada, Kazuyo, Mukai, Ririka, Matsumoto, Kiyoka, Nakamura, Mitsuhiro“…Moreover, individuals receiving platinum compounds, sulfonamides (plain), interferons, and antivirals for HCV infection therapy should be carefully observed for DIHL for at least several months.…”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32447por Björnsson, Einar S., Medina‐Caliz, Inmaculada, Andrade, Raul J., Lucena, M. Isabel“…No relapses of AIH were observed when IS was stopped after interferons, imatinib, diclofenac, and methylprednisolone. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32448Deciphering the Fine-Tuning of the Retinoic Acid-Inducible Gene-I Pathway in Teleost Fish and Beyondpor Jami, Raphaël, Mérour, Emilie, Lamoureux, Annie, Bernard, Julie, Millet, Jean K., Biacchesi, Stéphane“…Interferons are the first lines of defense against viral pathogen invasion during the early stages of infection. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32449por Fillatreau, Simon“…Bradford et al.(1) now provide evidence that autoantibodies can also be protective by neutralizing type I interferons (IFNs) and restraining the activation of pathogenic B cells.…”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32450“…SIMPLE SUMMARY: The development of colorectal cancer (CRC) can be affected by various inflammatory mediators, such as tumor necrosis factor, nuclear factor kappa B, interleukins, and interferons. Moreover, these inflammatory mediators can be reciprocally affected by gut microbiota. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32451“…(https://doi.org/10.1084/jem.20171749) report an unanticipated role for cGAMP in priming and activation of inflammasomes in addition to its well-characterized function as an endogenous second messenger inducing type I interferons in the cytosolic DNA-sensing pathway.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32452por Ullah, Tomalika R., Johansen, Matt D., Balka, Katherine R., Ambrose, Rebecca L., Gearing, Linden J., Roest, James, Vivian, Julian P., Sapkota, Sunil, Jayasekara, W. Samantha N., Wenholz, Daniel S., Aldilla, Vina R., Zeng, Jun, Miemczyk, Stefan, Nguyen, Duc H., Hansbro, Nicole G., Venkatraman, Rajan, Kang, Jung Hee, Pang, Ee Shan, Thomas, Belinda J., Alharbi, Arwaf S., Rezwan, Refaya, O’Keeffe, Meredith, Donald, William A., Ellyard, Julia I., Wong, Wilson, Kumar, Naresh, Kile, Benjamin T., Vinuesa, Carola G., Kelly, Graham E., Laczka, Olivier F., Hansbro, Philip M., De Nardo, Dominic, Gantier, Michael P.“…TANK-binding kinase 1 (TBK1) is a key signalling component in the production of type-I interferons, which have essential antiviral activities, including against SARS-CoV-2. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32453por Liu, Siqi, Chen, Jueqi, Cai, Xin, Wu, Jiaxi, Chen, Xiang, Wu, You-Tong, Sun, Lijun, Chen, Zhijian J“…RNA virus infections are detected by the RIG-I family of receptors, which induce type-I interferons through the mitochondrial protein MAVS. …”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32454por Coroadinha, Ana Sofia“…Some of these RFs are ubiquitously expressed in mammalian cells, while others are cell-specific, and others still are expressed only upon induction by danger signals as type I interferons. Cell restriction factors have evolved to protect the organism against infectious diseases and tissue damage. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32455“…Additional agents, such as rimantadine and intranasal interferons, and newer approaches, including thе use of combination chemotherapy, offer promise for the improved management of viral respiratory tract infections.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32456Publicado 2022“…Deacetylation of specific lysine residues in the DNA-binding domain of the transcription factors IRF3 and IRF7 by SIRT1 is necessary for liquid–liquid phase separation and transactivation of type I interferons. SIRT1 agonists partially restored the impaired innate immune responses in senescent cells and aged mice, suggestive of a possible strategy for preventing innate immunosenescence.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32457por Ben-Efraim, S.“…Interleukins 2, 4, 6, 7, 12 and the interferons were extensively tested for their therapeutic effectiveness in experimental tumour models and in cancer clinical trials. …”
Publicado 1997
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
32458“…NETs contribute to the pathogenesis of autoimmunity by exposing cryptic autoepitopes, which may facilitate the generation of autoantibodies, induce the production of interferons, and activate the complement cascade. In SLE, augmented disease activity and renal disease are associated with increased NET formation, so that NETs could serve as a marker for the monitoring of disease activity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32459por Dickinson, Matthew, Kliszczak, Anna E., Giannoulatou, Eleni, Peppa, Dimitra, Pellegrino, Pierre, Williams, Ian, Drakesmith, Hal, Borrow, Persephone“…Human immunodeficiency virus type 1 (HIV-1) infection triggers rapid induction of multiple innate cytokines including type I interferons, which play important roles in viral control and disease pathogenesis. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
32460por Padayachee, Yorissa, Flicker, Sabine, Linton, Sophia, Cafferkey, John, Kon, Onn Min, Johnston, Sebastian L., Ellis, Anne K., Desrosiers, Martin, Turner, Paul, Valenta, Rudolf, Scadding, Glenis Kathleen“…Unsurprisingly it has a strong immune defense system, with involvement of innate (e.g., epithelial barrier, muco- ciliary clearance, nasal secretions with interferons, lysozyme, nitric oxide) and acquired (e.g., secreted immunoglobulins, lymphocytes) arms. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto