Materias dentro de su búsqueda.
Mostrando 33,541 - 33,560 Resultados de 33,745 Para Buscar '"interferón"', tiempo de consulta: 0.70s Limitar resultados
  1. 33541
    “…PBMCs were challenged with an Australian strain of WNV (WNV(NSW2011)) and transcriptomes were quantified at 2, 6, 12 and 24 h post-infection (pi) using qRT-PCR. Type I and II interferons (IFNα, β and γ) mRNA transcription increased following WNV exposure, as did the transcripts for IL1α, IL1β, IL6, IL8, and IL22, but with slightly varying kinetics. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Kinetics of the West Nile virus induced transcripts of selected cytokines and Toll-like receptors in equine peripheral blood mononuclear cells
  2. 33542
    “…One effective approach is to modulate the crosstalk between NK cells and dendritic cells, which produce NK cell-stimulating cytokines like type I interferons (IFN), IL-12, IL-15, and IL-18 upon retrovirus sensing or infection. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Insufficient natural killer cell responses against retroviruses: how to improve NK cell killing of retrovirus-infected cells
  3. 33543
    “…BACKGROUND: Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines which participate in clearing viral infections. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    RIG-I overexpression decreases mortality of cigarette smoke exposed mice during influenza A virus infection
  4. 33544
    “…Virulent NDV was found to block toll-like receptor (TLR) 7 expression, inducing higher expression of type I interferons in chicken macrophages at the late stage of viral infection. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Enhanced Replication of Virulent Newcastle Disease Virus in Chicken Macrophages Is due to Polarized Activation of Cells by Inhibition of TLR7
  5. 33545
    “…Human infection with highly pathogenic avian influenza viruses (HPAIV) is often associated with severe tissue damage due to hyperinduction of interferons and proinflammatory cytokines. The reasons for this excessive cytokine expression are still incompletely understood, which has hampered the development of efficient immunomodulatory treatment options. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Phosphorylation of TRIM28 Enhances the Expression of IFN-β and Proinflammatory Cytokines During HPAIV Infection of Human Lung Epithelial Cells
  6. 33546
    “…SLFN12 is a particularly compelling target of further research, as this gene is known to be down-regulated during T cell activation and up-regulated by type I interferons (IFNs), which are used to treat MS.…”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Increased DNA methylation of SLFN12 in CD4(+) and CD8(+) T cells from multiple sclerosis patients
  7. 33547
    “…STAT1 has a key role in the regulation of innate and adaptive immunity by inducing transcriptional changes in response to cytokines, such as all types of interferons (IFN). STAT1 exist as two splice isoforms, which differ in regard to the C-terminal transactivation domain (TAD). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment
  8. 33548
    “…BACKGROUND: Published literature suggests that early treatment with natalizumab (“escalation strategy”) is more effective than switch within the same class of immunomodulators (interferons/glatiramer acetate, “switching strategy”) in relapsing-remitting multiple sclerosis (RRMS) patients who failed first-line self-injectable disease-modifying treatment (DMT). …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Cost-effectiveness analysis of escalating to natalizumab or switching among immunomodulators in relapsing-remitting multiple sclerosis in Italy
  9. 33549
    “…One of the key factors associated with SLE pathogenesis is excessive production of type I interferons (IFNs). This could result from increased activation of type I IFN‐stimulating pathways, but also from decreased activation of type I IFN‐inhibitory pathways. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Dysregulated Fcγ receptor IIa‐induced cytokine production in dendritic cells of lupus nephritis patients
  10. 33550
    “…Myxovirus resistance A (MxA) is an antiviral protein induced by type I interferons α and β (IFN-α and IFN-β) that can inhibit virus replication. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Association of functional polymorphisms in the MxA gene with susceptibility to enterovirus 71 infection
  11. 33551
    “…Immuno-staining for both viruses and beta-tubulin, real-time quantitative PCR and ELISA assays targeting various genes (pathogen recognition receptors, interferons (IFN) type I, cytokines, and IFN-inducible genes) and proteins were performed to analyze the cell and the tissue responses. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    In vitro and ex vivo analyses of co-infections with swine influenza and porcine reproductive and respiratory syndrome viruses
  12. 33552
    “…COVID-19 is causing inflammation via TNF-α and interferons. IL-4 plays an eminent role in the activation of the JAK-STAT pathway and leads to the disturbing pro-inflammatory cytokine as well as further cause’s male infertility. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    The role of Interleukin-4 in COVID-19 associated male infertility – A hypothesis
  13. 33553
    por Kumar, V.
    Publicado 2020
    “…Upon recognition of MAMPs and DAMPs, TLRs activate downstream signaling pathways releasing several pro-inflammatory mediators [cytokines, chemokines, interferons, and reactive oxygen and nitrogen species (ROS or RNS)], which cause acute inflammation meant to control the pathogen and repair the damage. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets
  14. 33554
    “…Genes encoding various interferons, cytokines, chemokines, and mediators of JAK-STAT pathway were positively regulated in leukemia, NAFLD, and T2D cases. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A meta-analysis of comorbidities in COVID-19: Which diseases increase the susceptibility of SARS-CoV-2 infection?
  15. 33555
    “…Therefore, we performed experiments in domestic pigs to analyze the kinetics of representative circulating interferons (IFNs), interleukins (ILs), growth factors, tumor necrosis factors (TNFs), and chemokines induced by infection of type II virulent ASFV SY18. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Cytokine Storm in Domestic Pigs Induced by Infection of Virulent African Swine Fever Virus
  16. 33556
    “…STING is an endoplasmic reticulum (ER)-resident protein critical for sensing cytoplasmic DNA and promoting the production of type I interferons; however, the role of STING in B cell receptor (BCR) signaling remains unclear. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    STING regulates BCR signaling in normal and malignant B cells
  17. 33557
    “…Data suggest that some classes of DMT, including type 1 interferons and glatiramer acetate, may not significantly impair the response to vaccination. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Vaccine Considerations for Multiple Sclerosis in the COVID-19 Era
  18. 33558
    “…We previously reported haploinsufficiency of suppressor of cytokine signaling 1 (SOCS1), a negative regulator of type I and II interferons, as a genetic risk factor for MIS-C. OBJECTIVES: We aimed to identify additional genetic mechanisms underlying susceptibility to severe acute respiratory syndrome coronavirus 2–associated MIS-C. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C)
  19. 33559
    “…Type I interferons (IFN), a family of cytokines widely expressed in various tissues, play important roles in anti-infection immunity. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    Brucella spp. Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production
  20. 33560
    por de Cevins, Camille, Luka, Marine, Smith, Nikaïa, Meynier, Sonia, Magérus, Aude, Carbone, Francesco, García-Paredes, Víctor, Barnabei, Laura, Batignes, Maxime, Boullé, Alexandre, Stolzenberg, Marie-Claude, Pérot, Brieuc P., Charbit, Bruno, Fali, Tinhinane, Pirabakaran, Vithura, Sorin, Boris, Riller, Quentin, Abdessalem, Ghaith, Beretta, Maxime, Grzelak, Ludivine, Goncalves, Pedro, Di Santo, James P., Mouquet, Hugo, Schwartz, Olivier, Zarhrate, Mohammed, Parisot, Mélanie, Bole-Feysot, Christine, Masson, Cécile, Cagnard, Nicolas, Corneau, Aurélien, Brunaud, Camille, Zhang, Shen-Ying, Casanova, Jean-Laurent, Bader-Meunier, Brigitte, Haroche, Julien, Melki, Isabelle, Lorrot, Mathie, Oualha, Mehdi, Moulin, Florence, Bonnet, Damien, Belhadjer, Zahra, Leruez, Marianne, Allali, Slimane, Gras-Leguen, Christèle, de Pontual, Loïc, Fischer, Alain, Duffy, Darragh, Rieux-Laucat, Fredéric, Toubiana, Julie, Ménager, Mickaël M.
    Publicado 2021
    “…We also found a weak response to type I and type II interferons, hyperinflammation, and response to oxidative stress related to increased HIF-1α and Vascular endothelial growth factor (VEGF) signaling. …”
    Enlace del recurso
    Enlace del recurso
    Enlace del recurso
    Online Artículo Texto
    A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis
Herramientas de búsqueda: RSS