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Mostrando 381 - 400 Resultados de 33,745 Para Buscar '"interferón"', tiempo de consulta: 0.26s Limitar resultados
  1. 381
    “…Transcriptomic analyses of IRF1-deficient, TNF-stimulated FLSs define the interferon (IFN) pathway as a major target of IRF1. …”
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    IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes: JAKinibs suppress the interferon response in RA-FLSs
  2. 382
    “…Interferon gamma (IFNγ) supports effector responses of CD8(+) cytotoxic T lymphocytes (CTLs) and is a surrogate marker for detection of antigen-specific T cells. …”
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    Defective Interferon Gamma Production by Tumor-Specific CD8(+) T Cells Is Associated With 5′Methylcytosine-Guanine Hypermethylation of Interferon Gamma Promoter
  3. 383
    “…This retrospective cohort study aims to investigate interferon (IFN)-associated retinopathy incidence in patients with chronic hepatitis C virus (HCV) infection treated with pegylated interferon (PegIFN) plus ribavirin (RBV). …”
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    Analysis of Different Types of Interferon-Associated Retinopathy in Patients with Chronic Hepatitis C Virus Infection Treated with Pegylated Interferon Plus Ribavirin
  4. 384
    “…Recombinant interferon (IFN) β-1b was approved by the US Food and Drug Administration as the first disease-modifying therapy (DMT) for multiple sclerosis (MS) in 1993. …”
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    Interferons and Multiple Sclerosis: Lessons from 25 Years of Clinical and Real-World Experience with Intramuscular Interferon Beta-1a (Avonex)
  5. 385
    “…In this context, single nucleotide polymorphisms (SNPs) in the locus of interferon lambda 3 and 4 genes (IFNL3/4) have been important genetic markers of responsiveness to CHC as prognostic markers for the pegylated-Interferon-alpha/ribavirin (Peg-IFN-α/RBV). …”
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    Interferon-lambda 3 and 4 Polymorphisms Increase Sustained Virological Responses and Regulate Innate Immunity in Antiviral Therapy With Pegylated Interferon-Alpha
  6. 386
    por Su, Jianguo
    Publicado 2022
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    The discovery of type IV interferon system revolutionizes interferon family and opens up a new frontier in jawed vertebrate immune defense
  7. 387
    “…Here, we show that depletion of ATRX results in an overall impaired antiviral state by decreasing transcription and subsequent secretion of type I IFNs, which is followed by reduced expression of interferon-stimulated genes (ISGs). ATRX interacts with the transcription factor interferon regulatory factor 3 (IRF3) and associates with the IFN-β promoter to facilitate transcription. …”
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    The chromatin remodeling protein ATRX positively regulates IRF3-dependent type I interferon production and interferon-induced gene expression
  8. 388
    “…BACKGROUND: Elevated levels of interferons (IFNs) are a characteristic feature of systemic autoimmune rheumatic diseases (SARDs) and may be useful in predicting impending symptomatic progression in anti-nuclear antibody-positive (ANA(+)) individuals lacking a SARD diagnosis. …”
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    Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA(+) individuals without a systemic autoimmune rheumatic disease diagnosis
  9. 389
    “…When RNA viruses infect cells, viral RNA induces activation of retinoic acid-induced gene I and melanoma differentiation gene 5, which initiates downstream molecules and finally produces type I interferon (IFN-I) to regulate antiviral immune responses. …”
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    Avian Metapneumovirus Subgroup C Phosphoprotein Suppresses Type I Interferon Production by Blocking Interferon Regulatory Factor 3 Nuclear Translocation
  10. 390
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    Comparative effectiveness and safety of ribavirin plus interferon-alpha, lopinavir/ritonavir plus interferon-alpha, and ribavirin plus lopinavir/ritonavir plus interferon-alpha in patients with mild to moderate novel coronavirus disease 2019: study protocol
  11. 391
    “…BACKGROUND: Increased type 2 interferon (i.e., IFN-γ) signaling has been shown to be involved in airway inflammation in a subset of asthma patients who often show high levels of airway neutrophilic inflammation and poor response to corticosteroid treatment. …”
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    Parkin promotes airway inflammatory response to interferon gamma
  12. 392
    por Qing, Furong, Liu, Zhiping
    Publicado 2023
    “…Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs)-mediated signaling pathway and is essential for the production of type I interferon (IFN-I). …”
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    Interferon regulatory factor 7 in inflammation, cancer and infection
  13. 393
    “…Insufficient cytotoxic T lymphocyte infiltration and the accumulation of immunosuppressive cells within tumours are the primary factors responsible for the inadequate clinical effectiveness of breast cancer treatment. The stimulator of interferon genes (STING) represents a pivotal protein in the innate immune response. …”
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    Targeting the stimulator of interferon genes (STING) in breast cancer
  14. 394
    por Rich, Sheldon
    Publicado 2003
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    Shortcomings in Pharmacy Benefit Forecasting - Interferon Beta Products
  15. 395
    “…Cytosolic DNA activates the stimulator of interferon response genes (STING), a key signal transducer which triggers type I interferon (IFN-I) expression; hence, STING activation is expected to induce IFN-I response and adipocyte dysfunction. …”
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    Stimulator of Interferon Genes (STING) Triggers Adipocyte Autophagy
  16. 396
    “…Purpose: Increased type 2 interferon (i.e., IFN-γ) signaling has been shown to be involved in airway inflammation in a subset of asthma patients who often show high levels of airway neutrophilic inflammation and poor response to corticosteroid treatment. …”
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    Parkin Promotes Airway Inflammatory Response to Interferon Gamma
  17. 397
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    Editorial: Interferons: key modulators of the immune system in cancer
  18. 398
    “…Interferon-gamma (IFN-gamma) mediates diverse functions in bone marrow-derived phagocytes, including phagocytosis and microbe destruction. …”
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    Interferon-gamma alters the phagocytic activity of the mouse trophoblast
  19. 399
    por Rönnblom, Lars, Alm, Gunnar V
    Publicado 2003
    “…Patients with systemic lupus erythematosus (SLE) have ongoing interferon-α (IFN-α) production and serum IFN-α levels are correlated with both disease activity and severity. …”
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    Systemic lupus erythematosus and the type I interferon system
  20. 400
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    Chlorambucil and interferon for low grade non-Hodgkin's lymphoma.
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