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Mostrando 521 - 540 Resultados de 33,745 Para Buscar '"interferón"', tiempo de consulta: 0.35s Limitar resultados
  1. 521
    “…We aimed to evaluate the chemosensitising effect of interferon-beta (IFN-β). METHODS: BxPC-3, CFPAC-1, and Panc-1 cells were pre-treated with IFN-β followed by gemcitabine monotherapy. …”
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    Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer
  2. 522
    “…Regardless of asthma severity and adequate disease management, patients may experience acute exacerbations of symptoms and a loss of disease control, often triggered by respiratory infections. The interferon (IFN) family represents a group of cytokines that play a central role in the protection against and exacerbation of various infections and pathologies, including asthma. …”
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    Insights Into Type I and III Interferons in Asthma and Exacerbations
  3. 523
    por Frisch, Steven M., MacFawn, Ian P.
    Publicado 2020
    “…Here, we critically address the bidirectional interplay between interferons (focusing on type I) and cell senescence, with important implications for health and healthspan.…”
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    Type I interferons and related pathways in cell senescence
  4. 524
    por Gupta, Rahul
    Publicado 2020
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    The double edged interferon riddle in COVID-19 pathogenesis
  5. 525
    “…Treatment is principally supportive; however, there are several agents that are using in treating of COVID-19 patients. Interferons (IFNs) have shown to be crucial in fighting with COVID-19 disease and can be a suitable candidate in treatment of these patients. …”
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    Potential role of interferons in treating COVID-19 patients
  6. 526
    por Zhang, Zhenfeng, Urban, Stephan
    Publicado 2020
    “…Cellular innate immune responses, mainly interferon (IFN) response, are crucial for controlling invading viruses, while viruses counteract these responses to favor their propagation. …”
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    Interplay between Hepatitis D Virus and the Interferon Response
  7. 527
    “…In this model, hydroxychloroquine inhibits the responsiveness of these innate immune cells to virus-like stimuli and interferons. This is associated with a suppression of histone 3 lysine 27 acetylation and histone 3 lysine 4 trimethylation of inflammation-related genes, changes in the cellular lipidome, and decreased expression of interferon-stimulated genes. …”
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    Hydroxychloroquine Inhibits the Trained Innate Immune Response to Interferons
  8. 528
    “…Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral mechanisms. …”
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    Dysregulated Interferon Response Underlying Severe COVID-19
  9. 529
    “…Like most plasma membrane proteins, type I interferon (IFN) receptor (IFNAR) traffics from the outer surface to the inner compartments of the cell. …”
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    Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads
  10. 530
    “…Key to these responses are type I, II, and III interferons (IFNs), which are involved in inducing an antiviral response, as well as controlling and suppressing inflammation and immunopathology. …”
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    Aging and Interferons: Impacts on Inflammation and Viral Disease Outcomes
  11. 531
    “…Among promising biopharmaceuticals are interferons, first described by Isaacs and Lindenmann in 1957 and approved for clinical use in humans nearly thirty years later. …”
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    Interferon-Based Biopharmaceuticals: Overview on the Production, Purification, and Formulation
  12. 532
    por Choi, Hojun, Shin, Eui-Cheol
    Publicado 2021
    “…Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Type I and III interferon (IFN) responses act as the first line of defense against viral infection and are activated by the recognition of viruses by infected cells and innate immune cells. …”
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    Roles of Type I and III Interferons in COVID-19
  13. 533
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    Considering Personalized Interferon Beta Therapy for COVID-19
  14. 534
    por Decker, Thomas
    Publicado 2021
    “…Interferons establish innate antiviral immunity. Two recent papers in JEM by Lopez et al. (2021. …”
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    The early interferon catches the SARS-CoV-2
  15. 535
    “…Here, we report that cGAS-STING–dependent type 1 interferon (IFN) response drives intestinal regeneration and animal recovery from radiation injury. …”
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    Interferon b drives intestinal regeneration after radiation
  16. 536
    por Elliott, Eric Isaac, Wang, Andrew
    Publicado 2021
    “…In this issue, van Laarhoven et al.(1) describe five immunocompromised patients with prolonged COVID-19 successfully treated with interferon gamma (IFNγ).…”
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    Interferon gamma runs interference on persistent COVID-19
  17. 537
    “…Interferons are our first line of defense against invading viruses. …”
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    Clash of the titans: interferons and SARS-CoV-2
  18. 538
    “…Interferons are innate and adaptive cytokines involved in many biological responses, in particular, viral infections. …”
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    Off balance: Interferons in COVID-19 lung infections
  19. 539
    “…Recent evidence suggests the existence of a nexus between inflammatory pathways and the female sex hormone 17β-estradiol, resulting in increased interferon-stimulated genes (ISGs), autoantibodies, and dysregulation of immune cells in SLE. …”
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    Interferon Genes Are Influenced by 17β-Estradiol in SLE
  20. 540
    por Wang, Wen-Ming, Li, Feng, Jin, Hong-Zhong
    Publicado 2021
    “…Psoriasis is a chronic inflammatory disease that involves both the innate and adaptive immune systems. Type I interferons (IFNs), the production of which is partially regulated by toll-like receptors (TLRs), play an important role in the pathogenesis of psoriasis, especially psoriasis caused by skin trauma, known as the Koebner phenomenon. …”
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    Role of interferon regulatory factor-mediated signaling in psoriasis
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