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  1. 541
    por Jahun, Aminu S., Goodfellow, Ian G.
    Publicado 2021
    “…In this review, we provide a concise overview of the evidence establishing the significance of type I and type III interferon (IFN) responses in the restriction of noroviruses. …”
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    Interferon responses to norovirus infections: current and future perspectives
  2. 542
    “…Interferon-β (IFN-β) is a pleiotropic cytokine secreted in response to various pathological conditions and is clinically used for therapy of multiple sclerosis. …”
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    Interferon-β Activity Is Affected by S100B Protein
  3. 543
    “…IL-27 contributes to the immune response against viruses indirectly by increasing production of interferons (IFNs) which have various antiviral effects. …”
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    Antiviral Activities of Interleukin-27: A Partner for Interferons?
  4. 544
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    Interferon-gamma and neuropathy: balance between pain and neuroprotection
  5. 545
    por Shi, Weiye, Yao, Xu, Fu, Yu, Wang, Yingze
    Publicado 2022
    “…Interferon (IFN)-α is a cytokine that exhibits a wide range of biological activities and is used in various cancer treatments. …”
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    Interferon-α and its effects on cancer cell apoptosis
  6. 546
    “…Ropeginterferon alfa-2b is a novel mono-pegylated and extra-long-acting interferon, being developed for the treatment of myeloproliferative neoplasm (MPN) and chronic viral hepatitis. …”
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    Novel Pegylated Interferon for the Treatment of Chronic Viral Hepatitis
  7. 547
    “…Global or myeloid cell-specific deletion of interferon γ receptor (IFN-γR) markedly enhanced the crystalline silica-induced pulmonary injury in wild-type but not in NLRP3 deficient mice. …”
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    Impaired interferon-γ signaling promotes the development of silicosis
  8. 548
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    A Game of Infection – Song of Respiratory Viruses and Interferons
  9. 549
    “…BACKGROUND: To compare the effectiveness of dimethyl fumarate (DMF) with subcutaneous interferon beta-1a (IFNβ-1a) in controlling disease activity in patients with relapsing–remitting Multiple Sclerosis (MS). …”
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    Comparison of dimethyl fumarate and interferon outcomes in an MS cohort
  10. 550
    “…The detection of pathogen-associated molecular patterns can elicit the production of type-I interferons (IFNs), soluble cytokines that induce a transcriptional state inhibitory to viral replication. …”
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    Type-I Interferons in Alzheimer's Disease and Other Tauopathies
  11. 551
    “…The interferon (IFN) response is the major early innate immune response against invading viral pathogens and is even capable of mediating sterilizing antiviral immunity without the support of the adaptive immune system. …”
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    Microbiota regulation of viral infections through interferon signaling
  12. 552
    “…Herein, we report an under-appreciated role of STUB1 to dampen the interferon gamma (IFNγ) response. Genetic deletion of STUB1 increased IFNGR1 abundance on the cell surface and thus enhanced the downstream IFNγ response as showed by multiple approaches including Western blotting, flow cytometry, qPCR, phospho-STAT1 assay, immunopeptidomics, proteomics, and gene expression profiling. …”
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    STUB1 is an intracellular checkpoint for interferon gamma sensing
  13. 553
    “…PURPOSE: To evaluate the efficacy of intensive topical interferon alfa-2b (IFN) therapy in uveitic macular edema (UME). …”
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    Intensive topical interferon therapy in uveitic macular edema
  14. 554
    “…The OC microenvironment is regulated by Interferons (IFNs) known as a type of important cytokines. …”
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    The role of interferons in ovarian cancer progression: Hinderer or promoter?
  15. 555
    “…BACKGROUND: IRF9 is a transcription factor that mediates the expression of interferon-stimulated genes (ISGs) through the Janus kinase-Signal transducer and activator of transcription (JAK-STAT) pathway. …”
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    Phosphorylation of interferon regulatory factor 9 (IRF9)
  16. 556
    “…Autoantibody formation and immune complex formation are important mediators in lupus pathogenesis, but an important role of the type I interferon (IFN) pathway has been identified in SLE patients and mouse models of lupus. …”
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    Targeting type I interferons in systemic lupus erythematous
  17. 557
    por Reis, Gilmar, Moreira Silva, Eduardo A.S., Medeiros Silva, Daniela C., Thabane, Lehana, Campos, Vitoria H.S., Ferreira, Thiago S., Santos, Castilho V.Q., Nogueira, Ana M.R., Almeida, Ana P.F.G., Savassi, Leonardo C.M., Figueiredo-Neto, Adhemar D., Dias, Ana C.F., Freire Júnior, Adelino M., Bitarães, Carina, Milagres, Aline C., Callegari, Eduardo D., Simplicio, Maria I.C., Ribeiro, Luciene B., Oliveira, Rosemary, Harari, Ofir, Wilson, Lindsay A., Forrest, Jamie I., Ruton, Hinda, Sprague, Sheila, McKay, Paula, Guo, Christina M., Limbrick-Oldfield, Eve H., Kanters, Steve, Guyatt, Gordon H., Rayner, Craig R., Kandel, Christopher, Biondi, Mia J., Kozak, Robert, Hansen, Bettina, Zahoor, M. Atif, Arora, Paul, Hislop, Colin, Choong, Ingrid, Feld, Jordan J., Mills, Edward J., Glenn, Jeffrey S.
    Publicado 2023
    “…BACKGROUND: The efficacy of a single dose of pegylated interferon lambda in preventing clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid-19) is unclear. …”
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    Early Treatment with Pegylated Interferon Lambda for Covid-19
  18. 558
    “…BACKGROUND: Our aim was to determinate bone mineral density (BMD), levels of biochemical markers and cytokines in children with chronic hepatitis B treated with interferon (IFN)-alpha and to investigate effect of IFN-alpha therapy on these variables. …”
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    Bone mineral density and cytokine levels during interferon therapy in children with chronic hepatitis B: does interferon therapy prevent from osteoporosis?
  19. 559
    “…Viral infections induce CD8 T cell expansion and interferon (IFN)-γ production for defense, but the innate cytokines shaping these responses have not been identified. …”
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    Two Roads Diverged: Interferon α/β– and Interleukin 12–mediated Pathways in Promoting T Cell Interferon γ Responses during Viral Infection
  20. 560
    “…Here we demonstrate a novel function for these proteins in epithelial cells, namely, their ability to modulate signalling from type I/II interferon receptors (IFNRs). We show that LMP2A and LMP2B-expressing epithelial cells display decreased responsiveness to interferon (IFN)α and IFNγ, as assessed by STAT1 phosphorylation, ISGF3 and GAF-mediated binding to ISRE and GAS elements and luciferase reporter activation. …”
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    The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation
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