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561“…The hyponatremia recovered 6 months after the interferon-alpha 2b therapy was completely stopped. …”
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562“…BACKGROUND: Administration of exogenous interferon-γ (IFNγ) aggravates the symptoms of multiple sclerosis (MS), whereas interferon-β (IFNβ) is used for treatment of MS patients. …”
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563“…Alpha-interferon (alpha-IFN) and gamma-interferon (gamma-IFN) are highly effective biologic agents in the treatment of chronic myelogenous leukemia (CML). 4-hydroperoxycyclophosphamide (4-HC) is the most commonly used chemotherapeutic drug when purging bone marrow contaminated with malignant cells. …”
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564por Qu, Hongren, Yang, Limin, Meng, Shanshan, Xu, Lei, Bi, Yuhai, Jia, Xiaojuan, Li, Jing, Sun, Lei, Liu, Wenjun“…Chicken interferon α (ChIFN-α) and ChIFN-β are type I IFNs that are important antiviral cytokines in the innate immune system. …”
Publicado 2013
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565por Go, Yun Young, Li, Yanhua, Chen, Zhenhai, Han, Mingyuan, Yoo, Dongwan, Fang, Ying, Balasuriya, Udeni B. R.“…The objective of this study was to investigate the effect of equine arteritis virus (EAV) on type I interferon (IFN) production. Equine endothelial cells (EECs) were infected with the virulent Bucyrus strain (VBS) of EAV and expression of IFN-β was measured at mRNA and protein levels by quantitative real-time RT-PCR and IFN bioassay using vesicular stomatitis virus expressing the green fluorescence protein (VSV-GFP), respectively. …”
Publicado 2014
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567por Börnsen, Lars, Romme Christensen, Jeppe, Ratzer, Rikke, Hedegaard, Chris, Søndergaard, Helle B., Krakauer, Martin, Hesse, Dan, Nielsen, Claus H., Sorensen, Per S., Sellebjerg, Finn“…In experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, exogenous and endogenous type I interferons restrict disease severity. Recombinant interferon-β is used for treatment of multiple sclerosis, and some untreated multiple sclerosis patients have increased expression levels of type I interferon-inducible genes in immune cells. …”
Publicado 2015
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568por Castellano, Giuseppe, Cafiero, Cesira, Divella, Chiara, Sallustio, Fabio, Gigante, Margherita, Pontrelli, Paola, De Palma, Giuseppe, Rossini, Michele, Grandaliano, Giuseppe, Gesualdo, Loreto“…INTRODUCTION: Type I interferons are pivotal in the activation of autoimmune response in systemic lupus erythematous. …”
Publicado 2015
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569por Li, Sheng, Yang, Li-juan, Wang, Ping, He, Yu-jiao, Huang, Jun-mei, Liu, Han-wei, Shen, Xiao-fei, Wang, Fei“…BACKGROUND: Type I interferons (IFN-α/β) have broad and potent immunoregulatory and antiproliferative activities. …”
Publicado 2016
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570por Miyaki, Eisuke, Hiraga, Nobuhiko, Imamura, Michio, Uchida, Takuro, Kan, Hiromi, Tsuge, Masataka, Abe-Chayama, Hiromi, Hayes, C. Nelson, Makokha, Grace Naswa, Serikawa, Masahiro, Aikata, Hiroshi, Ochi, Hidenori, Ishida, Yuji, Tateno, Chise, Ohdan, Hideki, Chayama, Kazuaki“…Interferon (IFN) inhibits hepatitis C virus (HCV) replication through up-regulation of intrahepatic IFN-stimulated gene expression but also through activation of host immune cells. …”
Publicado 2017
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571por Vasquez, Marcos, Paredes-Cervantes, Vladimir, Aranda, Fernando, Ardaiz, Nuria, Gomar, Celia, Berraondo, Pedro“…Interferon alpha (IFNα) is a cytokine approved for the treatment of several types of cancer. …”
Publicado 2016
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572por Wróblewska, Anna, Bernat, Agnieszka, Woziwodzka, Anna, Markiewicz, Joanna, Romanowski, Tomasz, Bielawski, Krzysztof P., Smiatacz, Tomasz, Sikorska, Katarzyna“…Single nucleotide polymorphisms (SNPs) within DNA region containing interferon lambda 3 (IFNL3) and IFNL4 genes are prognostic factors of treatment response in chronic hepatitis C (CHC). …”
Publicado 2016
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573“…Background: This study was performed to compare the effects of low dose interferon beta-1 (IFN-β-1) (CinnoVex, 30 mcg) and high dose IFN-β-1 (REBIF, 44 mcg) on the reduction of the number and size of plaques in magnetic resonance imaging (MRI) in patients with multiple sclerosis (MS). …”
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574por Ito, Y.“…When animals and cells are infected with a virus, interferon is produced. Viral-nucleic acid is considered to be one of actual components for interferon induction. …”
Publicado 1994
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575“…Further bioinformatics and in vitro experimental analyses found that interferon regulatory factor 1 (IRF1) acted as an essential mediator of surface CRT exposure by sequential IFNβ-cisplatin combination. …”
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576por Park, Seok-Chan, Park, Jun Young, Choi, Jin Young, Lee, Sung-Geun, Eo, Seong Kug, Oem, Jae-Ku, Tark, Dong-Seob, You, Myungjo, Yu, Do-Hyeon, Chae, Joon-Seok, Kim, Bumseok“…We intraperitoneally infected three groups of mice: wild-type (WT), mice treated with blocking anti-type I interferon (IFN)-α receptor antibody (IFNAR Ab), and IFNAR knockout (IFNAR(−/−)) mice, with four doses of SFTSV (KH1, 5 × 10(5) to 5 × 10(2) FAID(50)). …”
Publicado 2020
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577por Rocha, Rebeca Froes, Del Sarto, Juliana L., Gomes, Giovanni F., Gonçalves, Mariana P., Rachid, Milene A., Smetana, Juliana H. C., Souza, Daniele G., Teixeira, Mauro Martins, Marques, Rafael Elias“…SLEV replication in the central nervous system (CNS) induces the local production of interferons (IFNs), which are attributed to host protection. …”
Publicado 2021
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578por Shi, Danrong, Chen, Keda, Lu, Xiangyun, Cheng, Linfang, Weng, Tianhao, Liu, Fumin, Wu, Nanping, Li, Lanjuan, Yao, HangpingEnlace del recurso
Publicado 2022
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579por Carreca, Anna Paola, Gaetani, Massimiliano, Busà, Rosalia, Francipane, Maria Giovanna, Gulotta, Maria Rita, Perricone, Ugo, Iannolo, Gioacchin, Russelli, Giovanna, Carcione, Claudia, Conaldi, Pier Giulio, Badami, Ester“…IFN-γ, on the other hand, triggered the intracellular expressions of two antiviral gate-keepers in target cells, namely, myxovirus-1 (MX1) and interferon-induced protein with tetratricopeptide repeats 1 (IFIT1). …”
Publicado 2022
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580por Rajendran, Ranjithkumar, Rajendran, Vinothkumar, Gupta, Liza, Shirvanchi, Kian, Schunin, Darja, Karnati, Srikanth, Giraldo-Velásquez, Mario, Berghoff, Martin“…Recombinant beta interferons-1 (IFNβ-1) are used as first line therapies in patients with relapsing multiple sclerosis (MS), a chronic inflammatory and neurodegenerative disease of the CNS. …”
Publicado 2022
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