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  1. 41
    por Werenne, John
    Publicado 1983
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    The Biology of the Interferon System
  2. 42
    por Stewart, William E., Lin, Leo S.
    Publicado 1979
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    Antiviral activities of interferons
  3. 43
    por Scott, Geoffrey M.
    Publicado 1986
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    Interferons: what future?
  4. 44
    Publicado 2013
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    INTERFERON: FOR THE COLD AND CANCER?
  5. 45
    por Niewold, Timothy B.
    Publicado 2020
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    Type I interferon
  6. 46
    “…Type I and Type II Interferons (IFN) are prominent members of the host innate immune response and are required for control of intracellular pathogens. …”
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    Exogenous Interferon-α and Interferon-γ Increase Lethality of Murine Inhalational Anthrax
  7. 47
    “…Transcriptional activator interferon regulatory factor (IRF)-1 and repressor IRF-2 are known to play a critical role in the regulation of interferon (IFN) responses and oncogenesis in fibroblasts. …”
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    Regulation of interferon responses in medulloblastoma cells by interferon regulatory factor-1 and -2.
  8. 48
    “…Long non-coding RNAs (lncRNAs) play critical roles in diverse cellular processes; however, their involvement in many critical aspects of the immune response including the interferon (IFN) response remains poorly understood. …”
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    Negative regulation of the interferon response by an interferon-induced long non-coding RNA
  9. 49
    “…Interferons (IFNs) are key cytokines identified in vertebrates and evolutionary dominance of intronless IFN genes in amniotes is a signature event in IFN evolution. …”
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    Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity
  10. 50
    “…BACKGROUND: Recent studies have shown that gamma interferon (IFN-γ) synergizes with the innate IFNs (IFN-α and IFN-β) to inhibit herpes simplex virus type 1 (HSV-1) replication in vitro. …”
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    Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma
  11. 51
    “…Type I Interferons (IFNs), including numerous IFNα subtypes and IFNβ, are key molecules during innate and adaptive immune responses against viral infections. …”
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    Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection
  12. 52
    Publicado 1993
    “…Th2-type immune responses are characterized by Th cells that produce increased levels of interleukin-4 (IL-4) and decreased levels of interferon gamma (IFN- gamma). The induction of either a Th1- or a Th2-like phenotype may be critically controlled by the antigen-presenting cells and their cytokines, e.g., IFN-alpha. …”
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    Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells
  13. 53
    “…Current treatment of chronic hepatitis C with pegylated interferon and ribavirin has the ability to eliminate viral infection in about half of the patients treated. …”
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    Retreatment of Patients Nonresponsive to Pegylated Interferon and Ribavirin with Daily High-Dose Consensus Interferon
  14. 54
    “…BACKGROUND: Induction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. …”
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    Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression
  15. 55
    “…Recent genome-wide association studies suggest distinct roles for 12 human interferon-alpha (IFN-α) and 3 IFN-λ subtypes that may be elucidated by defining the expression patterns of these sets of genes. …”
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    Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent
  16. 56
    “…The method was applied to mutate interferon-γ receptor 1 (IFN-γ-Rx) to increase its affinity to natural ligand IFN-γ, protein important for innate immunity. …”
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    Increasing Affinity of Interferon-γ Receptor 1 to Interferon-γ by Computer-Aided Design
  17. 57
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    Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent
  18. 58
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    Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production
  19. 59
    “…Interferons (IFNs) are a group of cellular proteins with critical roles in the regulation of immune responses in the course of microbial infections. …”
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    Interaction Between Non-Coding RNAs and Interferons: With an Especial Focus on Type I Interferons
  20. 60
    Publicado 1983
    “…The interferon (IFN)-induced enzyme 2-5A synthetase was elevated in mononuclear cells from both serum IFN-positive and -negative systemic lupus erythematosus (SLE) patients. …”
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    Interferon-induced 2'-5' adenylate synthetase in vivo and interferon production in vitro by lymphocytes from systemic lupus erythematosus patients with and without circulating interferon
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