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583por Armstrong, John A.Materias: “…Interferon Induction ⋅ II…”
Publicado 1970
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584por Kajihara, Nabeel, Tanaka, Yoshino, Takeuchi, Riko, Kobayashi, Takuto, Tanji, Masafumi, Ataka, Tsukasa, Nakano, Shiho, Yamada, Taisho, Takaoka, Akinori, Hasegawa, Yoshinori, Seino, Ken-Ichiro, Wada, Haruka“…In this study, we indicate the importance of the interferon regulatory factor 7 (Irf7) axis, including Irf7 and its downstream factors, within tumor cells in regulating immunogenicity. …”
Publicado 2023
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585“…The immunomodulatory effect of prophylactic intravesical instillations of interferon alpha 2b (IFN-alpha-2b) on interferon gamma (IFN-gamma) and interleukin 4 (IL-4) production by peripheral blood mononuclear cells (PBMCs) from patients with superficial transitional cell carcinoma (STCC) of the bladder has been analysed. …”
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586Publicado 1992“…The interferons are cytokines with antiviral, cell growth regulatory, and immunomodulatory activities. …”
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587por Oganesyan, Vaheh, Damschroder, Melissa M., Cook, Kimberly E., Wu, Herren, Dall’Acqua, William F.“…Recombinant human interferon α-2A (rhIFN-α-2A) has been crystallized in complex with the recombinantly produced Fab fragment of a therapeutic monoclonal antibody (MEDI545; IgG1/κ) which targets several human interferon α subtypes. …”
Publicado 2008
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588por Cimini, Eleonora, Bonnafous, Cécile, Bordoni, Veronica, Lalle, Eleonora, Sicard, Helene, Sacchi, Alessandra, Berno, Giulia, Gioia, Cristiana, D’Offizi, Gianpiero, Visco Comandini, Ubaldo, Vlassi, Chrysoula, Capobianchi, Maria Rosaria, Martini, Federico, Agrati, ChiaraEnlace del recurso
Publicado 2012
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589“…The strong stimulatory action of type I interferon is due to the fact that type I interferon uses not only the interferon receptor but also CD21 as a functional receptor for B cell activation.…”
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590“…Various endometrial genes in ruminant ungulates are regulated by conceptus interferon tau (IFNT). However, the effect of each IFNT isoform has not been carefully evaluated. …”
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591por Minter, Myles Robert, Main, Bevan Scott, Brody, Kate Maree, Zhang, Moses, Taylor, Juliet Marie, Crack, Peter John“…BACKGROUND: Neuro-inflammation has long been implicated as a contributor to the progression of Alzheimer’s disease in both humans and animal models. Type-1 interferons (IFNs) are pleiotropic cytokines critical in mediating the innate immune pro-inflammatory response. …”
Publicado 2015
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592por Edvardsen, Kine, Bjånesøy, Trine, Hellesen, Alexander, Breivik, Lars, Bakke, Marit, Husebye, Eystein S., Bratland, Eirik“…Autoimmune Addison's disease (AAD) is a disorder caused by an immunological attack on the adrenal cortex. The interferon (IFN)-inducible chemokine CXCL10 is elevated in serum of AAD patients, suggesting a peripheral IFN signature. …”
Publicado 2015
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593por Meissner, E. G., Kohli, A., Virtaneva, K., Sturdevant, D., Martens, C., Porcella, S. F., McHutchison, J. G., Masur, H., Kottilil, S.“…We previously observed changes in hepatic immunity during interferon (IFN)‐free therapy that correlated with favourable outcome in subjects with early liver disease. …”
Publicado 2016
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594por Gimeno Brias, Silvia, Marsden, Morgan, Forbester, Jessica, Clement, Mathew, Brandt, Cordelia, Harcourt, Katherine, Kane, Leanne, Chapman, Lucy, Clare, Simon, Humphreys, Ian R.“…Interferon lambda (IFNλ) is a group of cytokines that belong to the IL-10 family. …”
Publicado 2018
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595por Koestner, Wolfgang, Spanier, Julia, Klause, Tanja, Tegtmeyer, Pia-K., Becker, Jennifer, Herder, Vanessa, Borst, Katharina, Todt, Daniel, Lienenklaus, Stefan, Gerhauser, Ingo, Detje, Claudia N., Geffers, Robert, Langereis, Martijn A., Vondran, Florian W. R., Yuan, Qinggong, van Kuppeveld, Frank J. M., Ott, Michael, Staeheli, Peter, Steinmann, Eike, Baumgärtner, Wolfgang, Wacker, Frank, Kalinke, Ulrich“…Studies with type I interferon (IFN-I) receptor (IFNAR)-deficient mice revealed a key role of the IFN-I axis in the protection against CVB3 infection, whereas the source of IFN-I and cell types that have to be IFNAR triggered in order to promote survival are still unknown. …”
Publicado 2018
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596por Santer, Deanna M., Minty, Gillian E. S., Golec, Dominic P., Lu, Julia, May, Julia, Namdar, Afshin, Shah, Juhi, Elahi, Shokrollah, Proud, David, Joyce, Michael, Tyrrell, D. Lorne, Houghton, Michael“…Type III interferons (IFN-lambdas(λ)) are important cytokines that inhibit viruses and modulate immune responses by acting through a unique IFN-λR1/IL-10RB heterodimeric receptor. …”
Publicado 2020
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597“…We determined that E6 but not E7 interferes with the constitutive expression of some antiviral cytokines, including interferon (IFN)-β and the IFN-stimulated gene IFIT1. …”
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598por Li, Chuan, Luo, Fengming, Liu, Chengwu, Xiong, Nian, Xu, Zhihua, Zhang, Wei, Yang, Ming, Wang, Ye, Liu, Dan, Yu, Chao, Zeng, Jia, Zhang, Li, Li, Duo, Liu, Yanbin, Feng, Mei, Liu, Ruoyang, Mei, Jiandong, Deng, Senyi, Zeng, Zhen, He, Yuanhong, Liu, Haiyan, Shi, Zhengyu, Duan, Meng, Kang, Deying, Liao, Jiayu, Li, Weimin, Liu, Lunxu“…To compare the effectiveness of a novel genetically engineered recombinant super-compound interferon (rSIFN-co) with traditional interferon-alpha added to baseline antiviral agents (lopinavir–ritonavir or umifenovir) for the treatment of moderate-to-severe COVID-19. …”
Publicado 2021
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599por Liu, Xuelan, Xi, Dexian, Xu, Aiyun, Wang, Yuan, Song, Tao, Ma, Tiantian, Ye, Hong, Li, Lin, Xu, Fazhi, Zheng, Hao, Li, Jinnian, Sun, Feifei“…The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway plays a vital role in sensing viral DNA in the cytosol, stimulating type I interferon (IFN) production and triggering the innate immune response against DNA virus infection. …”
Publicado 2022
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600por Liang, Yaxin, Liu, Rongrong, Zhang, Jiahui, Chen, Yixin, Shan, Shijuan, Zhu, Yaoyao, Yang, Guiwen, Li, Hua“…BACKGROUND: Interferon (IFN) regulatory factors (IRFs) is a kind of transcription factors, which play an important role in regulating the expression of type I IFN and related genes. …”
Publicado 2022
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