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661por Han, Ziying, Nogusa, Shoko, Nicolas, Emmanuelle, Balachandran, Siddharth, Taylor, John“…The best antiviral therapy is weekly administration for at least one year of high doses of interferon alpha. This efficacy of interferon therapy has been puzzling in that HDV replication in transfected cell lines is reported as insensitive to administration of interferon alpha or gamma. …”
Publicado 2011
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662por Zaidi, M. Raza, Davis, Sean, Noonan, Frances P., Graff-Cherry, Cari, Hawley, Teresa S., Walker, Robert L., Feigenbaum, Lionel, Fuchs, Elaine, Lyakh, Lyudmila, Young, Howard A., Hornyak, Thomas J., Arnheiter, Heinz, Trinchieri, Giorgio, Meltzer, Paul S., De Fabo, Edward C., Merlino, Glenn“…UVB-induced melanocyte activation, characterized by aberrant growth and migration, was abolished by antibody-mediated systemic blockade of interferon-γ (IFN-γ), but not type-I interferons. IFN-γ was produced by macrophages recruited to neonatal skin by UVB-induced ligands to the chemokine receptor Ccr2. …”
Publicado 2011
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663por Lotrich, Francis E.“…Major Depressive Disorder (MDD) during interferons (IFN-α) treatment can occur within a few months of therapy, and shares many homologies with other forms of MDD, Most patients are resilient to the side effect ofinterferon-induced depression (IFN-MDD), but 15% to 40% are vulnerable. …”
Publicado 2009
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664“…Multiple sclerosis (MS) patients of African ancestry have a more aggressive disease course than white patients and could be resistant to interferon-beta (INFB). Methods. We studied the impact of INFB in treatment-naive Afro-Caribbean (AC) with clinically definite MS using our European Database for Multiple Sclerosis (EDMUS) (2003–2010). …”
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665“…Regulation of epidermal proliferation and differentiation is critical for maintenance of cutaneous homeostasis. Interferon Regulatory Factor 6 (Irf6) deficient mice die perinatally and exhibit ectopic proliferation and defective epidermal differentiation. …”
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667por Asadi Noghabi, Ahmad Ali, Zandi, Mitra, Mehran, Abbas, Alavian, Seyed Moayed, Dehkordi, Ali Hasanpour“…The intervention included teaching them the method of self injection of Interferon alpha 2 b, giving them educational pamphlets and then following their continuing treatment with interferon. …”
Publicado 2010
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668por Konishi, Hideyuki, Okamoto, Koichi, Ohmori, Yusuke, Yoshino, Hitoshi, Ohmori, Hiroshi, Ashihara, Motooki, Hirata, Yuichi, Ohta, Atsunori, Sakamoto, Hiroshi, Hada, Natsuko, Katsume, Asao, Kohara, Michinori, Morikawa, Kazumi, Tsukuda, Takuo, Shimma, Nobuo, Foster, Graham R., Alazawi, William, Aoki, Yuko, Arisawa, Mikio, Sudoh, Masayuki“…Standard therapy involves an interferon (IFN)-α-based regimen, and efficacy of therapy has been significantly improved by the development of protease inhibitors. …”
Publicado 2012
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669por Johnston, Sara C, Lin, Kenny L, Connor, John H, Ruthel, Gordon, Goff, Arthur, Hensley, Lisa E“…RESULTS: The purpose of this study was to investigate the prophylactic and therapeutic potential of interferon-β (IFN-β) for use against monkeypox virus. …”
Publicado 2012
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670“…The cellular defense to infection depends on accurate activation of transcription factors and expression of select innate immunity genes. Interferon regulatory factor 5 (IRF5), a risk factor for systemic lupus erythematosus, is activated in response to pathogen recognition receptor engagement and downstream effector molecules. …”
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671por Feng, Yun, Diao, Ni, Shao, Lingyun, Wu, Jing, Zhang, Shu, Jin, Jialin, Wang, Feifei, Weng, Xinhua, Zhang, Ying, Zhang, Wenhong“…This study aimed to assess performance of interferon-gamma release assay (IGRA) in diagnosis of active tuberculosis (ATB) with pulmonary and extrapulmonary involvements, and to determine the diagnostic role of IGRA (T-SPOT.TB) and tuberculin skin test (TST) in BCG-vaccinated population. …”
Publicado 2012
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672por Vesenbeckh, Silvan M., Schönfeld, Nicolas, Mauch, Harald, Bergmann, Thorsten, Wagner, Sonja, Bauer, Torsten T., Rüssmann, Holger“…Interferon gamma release assays (IGRAs) are in vitro immunologic diagnostic tests used to identify Mycobacterium tuberculosis infection. …”
Publicado 2012
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674por Wimbauer, Fritz, Yang, Caihong, Shogren, Kristen L, Zhang, Minzhi, Goyal, Ribu, Riester, Scott M, Yaszemski, Michael J, Maran, Avudaiappan“…In this report, we have investigated whether interferon (IFN) pathway is involved in 2-ME-induced anti-tumor effects in osteosarcoma cells. …”
Publicado 2012
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675“…Although monocytes are normally susceptible to infection, pretreatment with pro-inflammatory cytokine interferon-γ (IFN-γ) activates cellular defense mechanisms that increase intracellular killing of Brucella and prevents bacterial replication. …”
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676“…Type I interferons (IFNα/β) provide a primary defense against infection. …”
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677“…PURPOSE: To evaluate retinopathy associated with interferon therapy in patients with chronic hepatitis C. …”
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680por Selcukbiricik, Fatih, Tural, Deniz, Senel, Tuba Elif, Sarıca, Ahmet, Soyluk, Ozlem, Serdengecti, Suheyla“…Introduction. Interferon is a glycoprotein produced by assigned cells of immune system. …”
Publicado 2012
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