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  1. 861
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    Inhibition of NOS1 promotes the interferon response of melanoma cells
  2. 862
    “…No specific treatment is currently available for COVID-19, and the discovery of effective therapeutics requires understanding the effective immunologic and immunopathologic mechanisms behind this infection. Type-I interferons (IFN-Is), as the critical elements of the immediate immune response against viral infections, can inhibit the replication and spread of the viruses. …”
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    Type-I interferons in the immunopathogenesis and treatment of Coronavirus disease 2019
  3. 863
    “…Interferons (IFNs) are an essential part of innate immunity and contribute to adaptive immune responses. …”
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    Interferon Signaling-Dependent Contribution of Glycolysis to Rubella Virus Infection
  4. 864
    “…Interferon epsilon (IFNe) is a recently described cytokine that is constitutively expressed in the female reproductive tract. …”
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    Defining a role for Interferon Epsilon in normal and complicated pregnancies
  5. 865
    “…Stimulator of interferon gene (STING), an intracellular receptor in the endoplasmic reticulum, could induce the production of cytokines such as type I interferon (IFN) by activating the cGAS-STING signal pathway. …”
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    Activation of Stimulation of Interferon Genes (STING) Signal and Cancer Immunotherapy
  6. 866
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    Remdesivir modifies interferon response in hospitalized COVID-19 patients
  7. 867
    “…While Spike mutations that enhance virus infectivity or neutralizing antibody evasion may drive the emergence of these novel variants, studies documenting a critical role for interferon responses in the early control of SARS-CoV-2 infection, combined with the presence of viral genes that limit these responses, suggest that interferons may also influence SARS-CoV-2 evolution. …”
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    Interferon resistance of emerging SARS-CoV-2 variants
  8. 868
    “…Interferons (IFN) are cytokines which, upon binding to cell surface receptors, trigger a series of downstream biochemical events including Janus Kinase (JAK) activation, phosphorylation of Signal Transducer and Activator of Transcription protein (STAT), translocation of pSTAT to the nucleus and transcriptional activation. …”
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    Small Molecule Inhibitors of Interferon‐Induced JAK‐STAT Signalling
  9. 869
    “…Plasmodium parasites that cause malaria undergo obligatory development and replication in hepatocytes before infecting red blood cells and initiating clinical disease. While type I interferons (IFNs) are known to facilitate innate immune control to Plasmodium in the liver, how they do so has remained unresolved, precluding the manipulation of such responses to combat malaria. …”
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    Direct type I interferon signaling in hepatocytes controls malaria
  10. 870
    “…INTRODUCTION: Interferon (IFN)-β is known as an environmental trigger for the occurrence of autoimmune thyroid disease (AITD). …”
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    Differential serum interferon-β levels in autoimmune thyroid diseases
  11. 871
    “…Many cytokines take part in this process, including interferon. The study aimed to quantify certain cytokines involved in the pathomechanism of primary Sjögren syndrome (IL2, IL5, IL6, IL10, IL13, TNFα, IFNγ) and determine their common clinical correlation. …”
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    Interferon Gamma Targeted Therapy: Is It Justified in Primary Sjögren’s Syndrome?
  12. 872
    “…Trisomy 21 autoimmunity and HLH are both thought to be driven by interferon gamma. Targeting therapy toward interferon signaling in both HLH and autoimmunity in trisomy 21 may have potential therapeutic benefits. …”
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    Hemophagocytic lymphohistocytosis in trisomy 21: successful treatment with interferon inhibition
  13. 873
    por Roy, Ethan, Cao, Wei
    Publicado 2022
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    Glial interference: impact of type I interferon in neurodegenerative diseases
  14. 874
    por Nocturne, Gaetane, Mariette, Xavier
    Publicado 2022
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    Interferon signature in systemic autoimmune diseases: what does it mean?
  15. 875
    “…We investigated the interplay between the type I interferon (IFN)-mediated innate immune response and MHV-68 latency using sensitive bioluminescent reporter mice. …”
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    Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo
  16. 876
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    Interferon with Dogma in Cytokine Release Syndrome and Acute Lung Injury
  17. 877
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    Editorial: Interferon and its antiviral effect in response to HBV infection
  18. 878
    por Bosco, Anthony
    Publicado 2023
    “…Decades of research has focused on the role of type I interferons in antiviral immunity and ensuing airway diseases, however, recent findings have highlighted several novel aspects of the interferon response that merit further investigation. …”
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    Emerging role for interferons in respiratory viral infections and childhood asthma
  19. 879
    “…Interferons (IFNs) are important in controlling the innate immune response to viral infections. …”
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    Interferon therapy and its association with depressive disorders – A review
  20. 880
    “…Here we show that mitogen-induced expression of interferon (IFN) regulatory factor 4 (IRF-4), a lymphoid-specific member of the IFN family of transcription factors, is Rel dependent. …”
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    Rel Induces Interferon Regulatory Factor 4 (IRF-4) Expression in Lymphocytes: Modulation of Interferon-Regulated Gene Expression by Rel/Nuclear Factor κB
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