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  1. 901
    “…Three different cohorts (20 healthy volunteers, 20 patients with RRMS and ongoing interferon-beta treatment and 10 patients starting on interferon-beta) will receive standard interferon-beta-1a therapy for nine days. …”
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    Immune- and miRNA-response to recombinant interferon beta-1a: a biomarker evaluation study to guide the development of novel type I interferon- based therapies
  2. 902
    “…Interferons are a group of antiviral cytokines acting as the first line of defense in the antiviral immunity. …”
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    Cross-Species Antiviral Activity of Goose Interferons against Duck Plague Virus Is Related to Its Positive Self-Feedback Regulation and Subsequent Interferon Stimulated Genes Induction
  3. 903
    “…Interferon-γ (IFN-γ) represents one of the most important innate immunity responses in a host to combat infections of many human viruses including human herpesviruses. …”
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    Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein
  4. 904
    “…Found in substantial numbers at sites of potential infection they are increased at sites of angiogenesis and can be pivotal for the sensing and clearance of a variety of pathogens. Interferons (IFNs) are cytokines that are critical for host defence against intracellular pathogens. …”
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    Interferon α2 and interferon γ induce the degranulation independent production of VEGF‐A and IL‐1 receptor antagonist and other mediators from human mast cells
  5. 905
    “…INTRODUCTION: This study was designed to assess real-world outcomes of patients with multiple sclerosis (MS) who were stable on interferon (IFN) beta therapy in the year prior to switching to another IFN beta therapy versus those who continued on the initial treatment. …”
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    Outcomes of Stable Multiple Sclerosis Patients Staying on Initial Interferon Beta Therapy Versus Switching to Another Interferon Beta Therapy: A US Claims Database Study
  6. 906
    “…Transcriptional profiling and pathway analysis revealed that patients with a decreased LV EDVi showed an induction of type I interferon (IFN) signalling (type I IFN pathway: P value < 0.001; false discovery rate < 0.001). …”
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    Elevated monocyte-specific type I interferon signalling correlates positively with cardiac healing in myocardial infarct patients but interferon alpha application deteriorates myocardial healing in rats
  7. 907
    “…Previous reports suggest that type I and type II Interferon can co-operatively inhibit some virus replication, e.g. …”
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    Hyper-activated IRF-1 and STAT1 contribute to enhanced Interferon stimulated gene (ISG) expression by Interferon α and γ co-treatment in human hepatoma cells
  8. 908
    “…BACKGROUND: Both interferon beta-1b (IFN-β-1b) and interferon beta-1a (IFN-β-1a) are immunomodulators that require regular subcutaneous self-administration by patients with multiple sclerosis (MS). …”
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    Real-World Assessment of Interferon-β-1b and Interferon-β-1a Adherence Before and After the Introduction of the BETACONNECT(®) Autoinjector: A Retrospective Cohort Study
  9. 909
    “…Using this model, we showed that hiPSC-neurons do not mount an effective interferon-mediated antiviral response following VZV infection. …”
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    Activation of Interferon-Stimulated Genes following Varicella-Zoster Virus Infection in a Human iPSC-Derived Neuronal In Vitro Model Depends on Exogenous Interferon-α
  10. 910
    “…Type I interferons (IFNs) are central mediators of anti-viral and anti-bacterial host defence. …”
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    An Emerging Role for Type I Interferons as Critical Regulators of Blood Coagulation
  11. 911
    “…Porcine interferon α (poIFN-α) is a crucial cytokine that can prevent and treat viral infections. …”
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    Analysis of the Differential Expression and Antiviral Activity of Porcine Interferon-α In Vitro
  12. 912
    “…Interferon ε (IFNε) is a unique type I IFN that has been implicated in host defense against sexually transmitted infections (STIs). …”
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    Interferon ε restricts Zika virus infection in the female reproductive tract
  13. 913
    “…PURPOSE: Dry eye disease (DED) is characterized by altered ocular surface proinflammatory and antiinflammatory factors. Interferons (IFNs) are a class of pleiotropic cytokines well known for their antimicrobial, inflammatory, and immunomodulatory roles. …”
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    Type 1–type 2 interferon imbalance in dry eye disease
  14. 914
    “…We report here the French experience on a type I interferon pathway assay that has been set up and used routinely since 2018 in Lyon, France.…”
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    Assessment of type I interferon response in routine practice in France in 2022
  15. 915
    “…OBJECTIVES: We describe a new method, FlowSpot, to assess CMV-specific T-cell response by quantification of interferon-gamma (IFN-γ). CMV-specific, T-cell-released IFN-γ was captured by flow beads and measured via flow cytometry. …”
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    Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus
  16. 916
    “…We have shown that two evolutionarily conserved defense systems, autophagy and interferon (IFN), target viral RCs and inhibit viral replication collaboratively. …”
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    CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma
  17. 917
    “…In a single experimental research, virally infected mouse models showed elevated kisspeptin levels and low interferon levels. OBJECTIVE: The objective of the study was to evaluate the serum levels of kisspeptin and interferon (INF)-beta in GW patients. …”
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    Study of serum level of kisspeptin and interferon-beta in genital wart patients
  18. 918
    “…Hyperactive interferon (IFN) signaling is a hallmark of Down syndrome (DS), a condition caused by trisomy 21 (T21); strategies that normalize IFN signaling could benefit this population. …”
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    Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome
  19. 919
    “…Dexamethasone treatment in COVID-19 patients resulted in down-regulation of genes related to type I and II interferon (IFN) signaling in whole blood immune cells. …”
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    Dexamethasone attenuates interferon-related cytokine hyperresponsiveness in COVID-19 patients
  20. 920
    “…Introduction: Cardiac fibroblasts (CF) are crucial cells in damaged heart tissues, expressing TLR4, IFN-receptor and responding to lipopolysaccharide (LPS) and interferon-β (IFN-β) respectively. While CF interact with immune cells; however, their relationship with neutrophils remains understudied. …”
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    Interferon-β decreases LPS-induced neutrophil recruitment to cardiac fibroblasts
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