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  1. 981
    por Dummer, Reinhard, Mangana, Joanna
    Publicado 2009
    “…Conventional interferons including interferon-α (IFN-α) are cytokines used for years in the treatment of solid tumors and hematological malignancies. …”
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    Long-term pegylated interferon-α and its potential in the treatment of melanoma
  2. 982
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    Local interferon-β gene therapy ameliorates adjuvant arthritis in rats
  3. 983
    “…Interferons are key modulators of the immune system, and are central to the control of many diseases. …”
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    Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells
  4. 984
    “…BACKGROUND: Studies of the host response to infection often require quantitative measurement of the antiviral type I interferons (IFN-α/β) in biological samples. The amount of IFN is either determined via its ability to suppress a sensitive indicator virus, by an IFN-responding reporter cell line, or by ELISA. …”
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    Species-independent bioassay for sensitive quantification of antiviral type I interferons
  5. 985
    por Baum, Alina, García-Sastre, Adolfo
    Publicado 2009
    “…Virus recognition and induction of interferon (IFN) are critical components of the innate immune system. …”
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    Induction of type I interferon by RNA viruses: cellular receptors and their substrates
  6. 986
    “…Hepatitis C virus is a poor inducer of interferon (IFN), although its structured viral RNA can bind the RNA helicase RIG-I, and activate the IFN-induction pathway. …”
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    Hepatitis C Virus Controls Interferon Production through PKR Activation
  7. 987
    por Chak, Eric, Saab, Sammy
    Publicado 2010
    “…The standard treatment for chronic HCV is combination therapy with pegylated interferon-α and ribavirin. Although pegylated interferon and ribavirin has been used against HCV for close to a decade, advances in therapy have centered on doses and treatment durations. …”
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    Pegylated Interferon and Ribavirin Dosing Strategies to Enhance Sustained Virologic Response
  8. 988
    “…Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by increased type I interferons (IFNs) and multiorgan inflammation frequently targeting the skin. …”
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    The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus
  9. 989
    “…It is not known if the response to β-interferon is also different. AIM: To demonstrate the decrease in relapses with β-interferon in Indian patients with multiple sclerosis. …”
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    Beta-interferons in multiple sclerosis: A single center experience in India
  10. 990
    por Nagao, Yumiko, Sata, Michio
    Publicado 2010
    “…BACKGROUND: There has been little discussion about the importance of oral management and interferon (IFN) therapy, although management of the side effects of therapy for chronic hepatitis C has been documented. …”
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    Dental problems delaying the initiation of interferon therapy for HCV-infected patients
  11. 991
    “…The objective of this study was to assess the immunomodulatory effects of interferon-β (IFN-β) on inflammatory mediators in the lung after experimental SAH. …”
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    Interferon-β attenuates lung inflammation following experimental subarachnoid hemorrhage
  12. 992
    “…METHODOLOGY/PRINCIPAL FINDINGS: Here, using an in vitro model that enables a natural route of infection, we show that interferon alpha (IFNalpha) has the previously uncharacterized capacity to induce a quiescent HSV-1 and PRV infection in porcine TG neurons that shows strong similarity to in vivo latency. …”
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    Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro
  13. 993
    “…So far, there is no consensus on how to define and interpret interferon-gamma release assays (IGRA) conversions and reversions, or how to deal with such results. …”
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    Serial testing with an interferon-γ release assay in German healthcare workers
  14. 994
    “…A., Singh, D., Ray, D., W., Donn, R. P. Interferon-inducible factor 16 is a novel modulator of glucocorticoid action.…”
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    Interferon-inducible factor 16 is a novel modulator of glucocorticoid action
  15. 995
    “…Bunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator. …”
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    The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism
  16. 996
    “…However, data concerning conversion and reversion rates in serial testing of healthcare workers (HCWs) with an interferon-γ release assay are sparse. METHODS: Between February 2007 and September 2009, 670 HCWs in the University Hospital of Porto, Portugal were tested at least twice with QuantiFERON-TB(®) Gold In-Tube (QFT) for LTBI. …”
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    Serial testing with the interferon-γ release assay in Portuguese healthcare workers
  17. 997
    “…Serum interleukin-8 (IL-8) and interferon-alpha (IFN-α) levels have been estimated from a total of 88 individuals of which 19 were disease-free healthy individuals, and 69 were patients with thyroid diseases: goitre (N = 21), autoimmune diseases (N = 16), and carcinomas (N = 32). …”
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    Clinical Utility of Serum Interleukin-8 and Interferon-Alpha in Thyroid Diseases
  18. 998
    “…These results point to a coordinated action of IFN-α, IFN-γ and IL-12 in Be1 polarization of naive B-cells, and may provide new insights into the mechanisms by which type-I-interferons favor autoimmunity.…”
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    Interferon-Alpha Triggers B Cell Effector 1 (Be1) Commitment
  19. 999
    “…BACKGROUND: Type I interferons (IFN) are a heterogeneous group of cytokines central to innate and adaptive antiviral immune responses. …”
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    Porcine type I interferons: polymorphic sequences and activity against PRRSV
  20. 1000
    “…OBJECTIVE: T cells and level of the cytokine interferon-γ (IFN-γ) are increased in adipose tissue in obesity. …”
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    Cross-Talk Between Interferon-γ and Hedgehog Signaling Regulates Adipogenesis
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