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  1. 1081
    “…We report that Mal has a TLR-independent role in interferon-gamma (IFN-γ) receptor signaling. Mal-dependent IFN-γ receptor (IFNGR) signaling led to mitogen-activated protein kinase (MAPK) p38 phosphorylation and autophagy. …”
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    A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
  2. 1082
    “…Thus, bacterial suppression of autophagy not only enhances cell-autonomous survival but also suppresses more-systemic innate immune responses by limiting type I and type II interferons.…”
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    Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages
  3. 1083
    “…RESULTS: The 10 most up-regulated genes in the ventral posteromedial/posterolateral region of the thalamus were inflammatory genes, with the gene expression signature significantly enriched in interferon signaling genes. Interferon β levels were elevated in neurons, and interferon-stimulated genes were elevated mainly in microglia. …”
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    Induction of the type I interferon response in neurological forms of Gaucher disease
  4. 1084
    “…Complete deletion of interferon‐α/β receptor (Ifnar) using Ifnar1(−/−) mice significantly enhanced early microglia and macrophage activation in lesion areas. …”
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    Interferon‐beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization
  5. 1085
    “…In the United States, HCV genotype 1 constitutes about 75% of all infections. While interferon and ribavirin therapy was the cornerstone of treatment for many years, interferon-free treatments have become the standard of care with the emergence of new direct-acting agents, resulting in more effective treatment, shorter duration of therapy, better tolerability, lower pill burden, and ultimately better adherence. …”
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    Interferon-Free Treatments for Chronic Hepatitis C Genotype 1 Infection
  6. 1086
    “…PURPOSE: To investigate the effects of systemic and local interferon-beta-1a (IFN-β-1a) on prevention of epidural fibrosis using histopathological parameters. …”
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    Effects of Systemic and Local Interferon Beta-1a on Epidural Fibrosis
  7. 1087
    “…In the present study, we investigated how interferon (IFN)-α disrupts the extinction of conditioned fear and propose an approach to rescue IFN-α-induced neurologic impairment. …”
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    Minocycline attenuates interferon-α-induced impairments in rat fear extinction
  8. 1088
    “…We present a case of a young female with recurrent pericarditis due to interferon therapy. The role of interferon in adjuvant chemotherapy is well known and yields good effect, but this case highlights the very uncommon phenomena of interferon induced pericarditis and the significant distress it can cause.…”
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    Recurrent Pericarditis, an Unexpected Effect of Adjuvant Interferon Chemotherapy for Malignant Melanoma
  9. 1089
    “…Lentiviruses are able to establish persistent infection in their respective hosts despite a potent type-I interferon (IFN-I) response following transmission. …”
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    Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance
  10. 1090
    “…The use of chicken interferon gamma (chIFNγ) during vaccination is a potentially important but controversial approach that may improve the immune response to antigens. …”
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    Effects of Chicken Interferon Gamma on Newcastle Disease Virus Vaccine Immunogenicity
  11. 1091
    “…Associations between rodent transcriptomes from brain and cellular transcriptomes in response to T cell–derived cytokines suggest a strong interaction between social behavior and interferon-gamma (IFN-γ) driven responses. Concordantly, we demonstrate that inhibitory neurons respond to IFN-γ and increase GABAergic currents in projection neurons, suggesting that IFN-γ is a molecular link between meningeal immunity and neural circuits recruited for social behavior. …”
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    Unexpected role of interferon-γ in regulating neuronal connectivity and social behavior
  12. 1092
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    Interferon alpha-2b in giant ocular surface squamous neoplasia
  13. 1093
    “…Interferon-gamma (IFN-γ) is a pleiotropic cytokine that exerts anti-tumor and anti-osteoclastogenic effects. …”
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    A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma
  14. 1094
    “…This study was conducted to explore the effects of interferon tau (IFNT) on the intestinal microbiota and expression of interleukin 17 (IL-17) in the intestine of mice. …”
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    Interferon Tau Affects Mouse Intestinal Microbiota and Expression of IL-17
  15. 1095
    “…Significant impairment of the type I interferon (IFN-I) response is observed during productive HIV-1 infection. …”
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    Type I interferon responses are impaired in latently HIV infected cells
  16. 1096
    “…BACKGROUND: Interferons (IFNs) play a critical role in the host antiviral defense and are an essential component of current therapies against hepatitis C virus (HCV), a major cause of liver disease worldwide. …”
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    System-based proteomic analysis of the interferon response in human liver cells
  17. 1097
    “…Interferon (IFN) lambdas are critical antiviral effectors in hepatic and mucosal infections. …”
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    Interferon lambda 4 expression is suppressed by the host during viral infection
  18. 1098
    “…The human interferon (IFN) response is a key innate immune mechanism to fight virus infection. …”
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    The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy
  19. 1099
    “…Cutaneous reactions associated with interferons (IFNs) treatment are either localized or generalized. …”
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    Interferon-gamma-induced local leukocytoclastic vasculitis at the subcutaneous injection site
  20. 1100
    “…Post-translational protein modifications by ubiquitin and ubiquitin-like proteins, including SUMO and NEDD8, are critically involved in DNA damage response (DDR) and DNA damage tolerance (DDT). The expression of interferon-stimulated gene 15 (ISG15), the first identified ubiquitin-like protein, has recently been shown to be induced under various DNA damage conditions, such as exposure to UV, camptothecin, and doxorubicin. …”
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    Interferon-Stimulated Gene 15 in the Control of Cellular Responses to Genotoxic Stress
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