-
1141por Ishibashi, Daisuke, Homma, Takujiro, Nakagaki, Takehiro, Fuse, Takayuki, Sano, Kazunori, Satoh, Katsuya, Mori, Tsuyoshi, Atarashi, Ryuichiro, Nishida, Noriyuki“…In addition, cells and mice deficient in type I interferon receptor (subunit interferon alpha/beta receptor 1), exhibited higher susceptibility to 22L-prion infection. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1142por Sweeney, Louise, McCloskey, Alice P., Higgins, Gerard, Ramsey, Joanne M., Cryan, Sally-Ann, MacLoughlin, Ronan“…BACKGROUND: Interferon gamma (IFN-γ) is a clinically relevant immunomodulatory cytokine that has demonstrated significant potential in the treatment and management of respiratory diseases such as tuberculosis and pulmonary fibrosis. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1143“…Type I Interferons were first described for their profound antiviral abilities in cell culture and animal models, and later, they were translated into potent antiviral therapeutics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1144“…PURPOSE: Interferon alpha 2b (IFN-α2b) has been used as an adjunctive agent to treat conjunctival melanoma (CM), however its efficacy is unproved due to a paucity of data. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1145“…Interferon (IFN)-mediated antiviral responses are central to host defence against viral infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1146“…However, in mice carrying defects in the type I and type II interferon system, the virus grew to high titers and caused severe pathology. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1147“…Sensitivity and specificity of the interferon-γ release test for active tuberculosis screening were evaluated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1148“…In the last few years, it has been evidenced that mammalian reovirus encodes many different determinants that are involved in regulating the induction of the interferon response or in interfering with the action of interferon-stimulated gene products. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1149por Du, Jiang‐long, Ma, Peng, Wang, Chen, Zeng, Yan, Xue, Yu‐jia, Yang, Xue‐cai, Wan, Xue‐mei, Chang, Fan‐fan, Zhao, Tian‐yu, Jia, Xiao‐ye, Wang, Hai‐zhen, Liu, Jing, Ma, Zhong‐ren, Cao, Xin, Cai, Kui‐zhengEnlace del recurso
Publicado 2019
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1150por Ansari, M Azim, Aranday-Cortes, Elihu, Ip, Camilla LC, da Silva Filipe, Ana, Lau, Siu Hin, Bamford, Connor, Bonsall, David, Trebes, Amy, Piazza, Paolo, Sreenu, Vattipally, Cowton, Vanessa M, Hudson, Emma, Bowden, Rory, Patel, Arvind H, Foster, Graham R, Irving, William L, Agarwal, Kosh, Thomson, Emma C, Simmonds, Peter, Klenerman, Paul, Holmes, Chris, Barnes, Eleanor, Spencer, Chris CA, McLauchlan, John, Pedergnana, Vincent“…Here, we examined the role played by interferon lambda-4 (IFN-λ4) on HCV diversity; IFN-λ4 plays a crucial role in spontaneous clearance or establishment of chronicity following acute infection. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1151“…Interferon (IFN)-λ forms the type III IFN family. Although they signal through distinct receptors, type I (IFN-α/β) and type III IFNs elicit remarkably similar responses in cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1152por Dias, Bruna T., Dias-Teixeira, Karina Luisa, Godinho, Joseane P., Faria, Marilia S., Calegari-Silva, Teresa, Mukhtar, Maowia M., Lopes, Ulisses, Mottram, Jeremy C., Lima, Ana Paula C. A.“…Neutrophil elastase promotes Leishmania donovani infection via interferon-β.…”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1153“…In mammalian cells, an important sensor is the stimulator of interferon genes (STING) protein, which upon activation by bacterially-derived cyclic dinucleotides (cDNs) or cytosolic dsDNA (dsDNA), triggers type I interferons and pro-inflammatory cytokine production. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1154por Pulido-Ortega, Julieta, Talamás-Rohana, Patricia, Muñoz-Ortega, Martín Humberto, Aldaba-Muruato, Liseth Rubí, Martínez-Hernández, Sandra Luz, Campos-Esparza, María del Rosario, Cervantes-García, Daniel, Leon-Coria, Aralia, Moreau, France, Chadee, Kris, Ventura-Juárez, Javier“…We have previously shown that E. histolytica binds exogenous interferon gamma (IFN-γ) on its surface, and in this study, we explored whether exogenous IFN-γ could modulate parasite virulence. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1155
-
1156por Elder, Elizabeth G., Krishna, Benjamin A., Williamson, James, Lim, Eleanor Y., Poole, Emma, Sedikides, George X., Wills, Mark, O’Connor, Christine M., Lehner, Paul J., Sinclair, John“…Here, we use an unbiased proteomic screen to assess changes in host proteins induced by US28, revealing that interferon-inducible genes are downregulated by US28. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1157“…BACKGROUND: Interferon-gamma (IFN-γ) is an important mediator of type I immune response and has antiviral, immunoregulatory and anti-tumor properties, plays a wide range of roles in inflammation and autoimmune diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1158
-
1159por Zuo, Yibo, Feng, Qian, Jin, Lincong, Huang, Fan, Miao, Ying, Liu, Jin, Xu, Ying, Chen, Xiangjie, Zhang, Hongguang, Guo, Tingting, Yuan, Yukang, Zhang, Liting, Wang, Jun, Zheng, Hui“…Linear ubiquitination of STAT1 is removed rapidly by OTULIN upon type-I interferon stimulation, which facilitates activation of interferon-STAT1 signaling. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1160por Lai, Junzhong, Luo, Xuan, Tian, Shuoran, Zhang, Xing, Huang, Shanlu, Wang, Hanze, Li, Qiumei, Cai, Shaoli, Chen, Qi“…These data demonstrate a new and inverse correlation between Compound C and type I interferon production in response to dsDNA signaling.…”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto