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  1. 1141
    “…In addition, cells and mice deficient in type I interferon receptor (subunit interferon alpha/beta receptor 1), exhibited higher susceptibility to 22L-prion infection. …”
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  2. 1142
    “…BACKGROUND: Interferon gamma (IFN-γ) is a clinically relevant immunomodulatory cytokine that has demonstrated significant potential in the treatment and management of respiratory diseases such as tuberculosis and pulmonary fibrosis. …”
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  3. 1143
    “…Type I Interferons were first described for their profound antiviral abilities in cell culture and animal models, and later, they were translated into potent antiviral therapeutics. …”
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  4. 1144
    “…PURPOSE: Interferon alpha 2b (IFN-α2b) has been used as an adjunctive agent to treat conjunctival melanoma (CM), however its efficacy is unproved due to a paucity of data. …”
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  5. 1145
    “…Interferon (IFN)-mediated antiviral responses are central to host defence against viral infection. …”
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  6. 1146
    “…However, in mice carrying defects in the type I and type II interferon system, the virus grew to high titers and caused severe pathology. …”
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  7. 1147
    “…Sensitivity and specificity of the interferon-γ release test for active tuberculosis screening were evaluated. …”
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  8. 1148
    “…In the last few years, it has been evidenced that mammalian reovirus encodes many different determinants that are involved in regulating the induction of the interferon response or in interfering with the action of interferon-stimulated gene products. …”
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  9. 1149
  10. 1150
  11. 1151
    por Hermant, Pascale, Michiels, Thomas
    Publicado 2014
    “…Interferon (IFN)-λ forms the type III IFN family. Although they signal through distinct receptors, type I (IFN-α/β) and type III IFNs elicit remarkably similar responses in cells. …”
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  12. 1152
  13. 1153
    “…In mammalian cells, an important sensor is the stimulator of interferon genes (STING) protein, which upon activation by bacterially-derived cyclic dinucleotides (cDNs) or cytosolic dsDNA (dsDNA), triggers type I interferons and pro-inflammatory cytokine production. …”
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  14. 1154
  15. 1155
  16. 1156
    “…Here, we use an unbiased proteomic screen to assess changes in host proteins induced by US28, revealing that interferon-inducible genes are downregulated by US28. …”
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  17. 1157
    “…BACKGROUND: Interferon-gamma (IFN-γ) is an important mediator of type I immune response and has antiviral, immunoregulatory and anti-tumor properties, plays a wide range of roles in inflammation and autoimmune diseases. …”
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  18. 1158
  19. 1159
    “…Linear ubiquitination of STAT1 is removed rapidly by OTULIN upon type-I interferon stimulation, which facilitates activation of interferon-STAT1 signaling. …”
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  20. 1160
    “…These data demonstrate a new and inverse correlation between Compound C and type I interferon production in response to dsDNA signaling.…”
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